James Kohl

Long-term adaptation replaces evolution

Long-term adaptation is energy-dependent and biophysically constrained by the pheromone-controlled physiology of reproduction, which links the fixation of amino acid substitutions in organized genomes to all morphological and behavioral diversity. The molecular details of adaptation refute every aspect of neo-Darwinian pseudoscientific nonsense that has ever been touted by biologically uninformed science idiots. New discovery challenges long-held evolutionary theory Monash scientists involved in one of the world’s longest evolution experiments have debunked an established theory with a study that provides a…

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Exome Sequencing Impact in Routine Care

Summary: They placed the pseudoscientific nonsense about selection for beneficial mutations into the context of positive selection for mutations, which are caused by the virus-driven degradation of messenger RNA. The mutations have been linked to all pathology. It’s as if all theorists want to become known as “biologically uninformed science idiots” via their associations with others who have touted claims about “beneficial mutations.” US Air Force Studying Impact of Exome Sequencing in Routine Care Who, among my fellow veterans, and…

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Proteins “evolve” (revisited)

Complex evolutionary footprints revealed in an analysis of reused protein segments of diverse lengths Reported by Jay R. Feierman to the evolutionary psychology Yahoo Group as: Recycling at the molecular level: Protein evolution Reuse patterns in protein space reflect 3.7 billion y of evolution (58), restrained by the underlying physicochemical qualities of covalently linked amino acids. Autophagy links chirality from energy-dependent changes in electrons to ecosystems. For comparison, their claim is consistent with ridiculous misrepresentations of food energy-dependent biophysically constrained…

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For God and Country

Losers: Rediscovering an epigenetic key (2)

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity “Validation of associations reported elsewhere,” includes the detailed associations from 1996 in the molecular epigenetics section of: From fertilization to adult sexual behavior  and in my 2013 refutation of neo-Darwinian theories: Nutrient-dependent/pheromone-controlled adaptive evolution: a model  (Val370Ala is also known as rs3827760, also known as 1540T/C, 370A. It is a SNP in the ectodysplasin A receptor EDAR gene on chromosome 2.) Excerpt: Two additional recent reports link substitution…

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Losers: rediscovering an epigenetic key

Epigenetic mechanisms modulate differences in Drosophila foraging behavior Little is known about how genetic variation and epigenetic marks interact to shape differences in behavior. Reported as: An epigenetic key to unlock behavior change October 16, 2017 “One of the big questions in the Child & Brain Development program over the years has been how experience gets embedded in our biology and the mechanisms for that,” says Sokolowski. See for comparison: See Brain on stress: How the social environment gets under…

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Virulence: Out of stock

Virulence: An Infectious Card Game This product is currently out of stock and is on backorder. For comparison, pre-orders of “Cytosis: A Cell Biology Board Game”  are being shipped this month, and the “board game” adds “depth” to what could already have been learned from the “card game.” I ordered two cases of “Cytosis.” Players start with the creation of energy and link ATP from the creation of RNA to the creation of all biophysically constrained life on Earth. Players…

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For God and Country

Faith in evolution: Paleontology as a molecular science

Keeping the faith For the last 20 years, Mary Schweitzer, a paleontologist at North Carolina State University in Raleigh, has amassed a wealth of evidence that she’s isolated protein fragments from dinosaurs as much as 80 million years old. That bucks the conventional wisdom among paleontologists who argue that proteins, which are made of chains of amino acids, can’t survive more than 1 million years or so. So far, no group other than Schweitzer and her collaborators has managed to…

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Lethal virus kills 5 billion people?

Until death: Virus-driven failure of multisensory integration (3)

What Your Nose Knows: Sense of Smell and Your Health August 2016 What the Nose Knows May Affect Your Brain Health October 2017 Doty’s research found a strong connection between low scores on a 40-item smell test and damage to this area of the brain. His recent article in The Lancet outlines possible ways that sense of smell and overall brain health could be linked and “may be the genesis of many neurodegenerative diseases. See: ”Olfactory dysfunction in neurodegenerative diseases:…

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For God and Country

Energy-dependent structure and function: Until death (5)

Summary: If a player starts with evolution instead of the creation of energy that links ATP to the creation of RNA, the player is a loser. Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge. — Kalevi Kull Secular: Ancient Viruses Are Buried in Your DNA (2017) by…

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For God and Country

Energy-dependent structure and function: Until death (4)

The structure-energy landscape of NMDA receptor gating The NMDA receptor gating is complex, exhibiting multiple closed, open, and desensitized states; however, central questions regarding the conformations and energetics of the transmembrane domains as they relate to the gating states are still unanswered. Reported as: Molecule Movements Through Nerve Cells Could Lead to Multi-functional Drugs The subunits sit on each side of the channel and activate when they bind both glutamate and glycine neurotransmitter ligands and trigger the signaling pathway that…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, mathematicians, statisticians, philosophers and theologians. replaced: Randomness and Divine Providence Supported by the John Templeton...Read more