Energy expertise, evolution of yeasts, and better beer

Energy Expertise: Excerpt: Chris Hittinger studies the diversity and evolution of yeast carbon metabolism, which is controlled by a complex system of interacting genes that respond to different carbon sources and determine the organism’s energy-use strategy. By understanding how evolution has sculpted and rewired yeast gene networks to meet their different ecological needs, Hittinger hopes to better understand how to engineer complex biological systems to meet our energy needs. ​   My comment: Doxycycline induction appears to be used without…

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Innovative Neurotechnologies Link Sunlight to Precision Medicine

Brain Research Through Advancing Innovative Neurotechnologies “…is part of a new Presidential focus aimed at revolutionizing our understanding of the human brain.” It has been linked to the Presidential focus on Precision Medicine via nutrient-dependent RNA-mediated amino acid substitutions, which are essential to the stability of organized genomes. For example, fixation of amino acid substitutions in the context of the physiology of reproduction is linked to cell type differentiation in all individuals of all species via the conserved molecular mechanisms that…

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Hydrogen-Atom Transfer in DNA Base Pairs

I requested a reprint of this article from the senior author on 10/29/15 and received it on 12/18/15.  Scientific progress moves fast, and Hydrogen-Atom Transfer in DNA Base Pairs (2) appears before the continuation of this post is linked to Hydrogen-Atom Transfer in DNA Base Pairs (3) and others in this series. Ultraviolet Absorption Induces Hydrogen-Atom Transfer in G⋅C Watson–Crick DNA Base Pairs in Solution [subscription required] It was reported as: Researchers observe one of the world’s fastest chemical reactions…

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Phenols: Laws of physics meet biology

Can the second law of thermodynamics hold in cell cultures? Excerpt: …for in vivo systems, the rules for self-organization require further investigations (Stuart, 1995), especially for multi-cellular organisms considering the exchange of matter between different cell types. Knowing this will allow us to better predict the emergent properties of the “real” living systems. My comment: When Jay R. Feierman realizes how ridiculous his comments about mutations and evolution have become, he posts  links to articles like this one to the…

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Plasma created by sunlight and RNA–mediated epigenetic heredity

Australian student confirms that giant plasma tubes are floating above Earth Excerpt: The region of space around the Earth occupied by its magnetic field, called the magnetosphere, is filled with plasma created by the atmosphere being ionised by sunlight. My comment: Scientists have believed in the creation of these structures for more than 60 years. Now visual evidence confirms structures exist that are created by sunlight on contact with the Earth’s atmosphere. This reminds me of what someone who was…

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Positive feedback loops and epigenetic traps

Transcription factor trapping by RNA in gene regulatory elements Conclusion: …bidirectional transcription of active enhancers and promoters evolved, in part, to facilitate trapping of TFs at specific regulatory elements. The model also suggests that transcription of regulatory elements produces a positive-feedback loop that may contribute to the stability of gene expression programs in cells. The contribution of this TF trapping mechanism to cellular regulation has yet to be established but will be important to elucidate in future studies because much…

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Let there be anti-entropic light (3)

See also: Let there be anti-entropic light (1) and Let there be anti-entropic light (2) NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program and Putting chromatin in its place: the pioneer factor NeuroD1 modulates chromatin state to drive cell fate decisions were reported as: Master switch for brain development found Excerpts: 1)  …the brain is also one of the most complex organs in the body, and very little is understood about the molecular pathways that guide…

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Theorists can’t understand biology

See also: Neuroplasticity Thanks to Teresa Binstock for calling my attention to this:   Thanks to Anna Di Cosmo for calling the attention of others to this: My comment: Attempts to explain the “binding problem” of integration in the context of ecoimmunology and disease ecology compared to emergence and evolution are examples of how much pseudoscientific nonsense has been accepted and touted in the context of the neo-Darwinian “Modern Synthesis.” For comparison, serious scientists have detailed a model of top-down…

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Physicists: Desperate Acts

Participation on the FB group Thinking Allowed Original led to an invite by Ulla Mattfolk to participate on her secret group  Quantum Biology, coherence and decoherence. On January 22 at 11:45pm, discussion led me to ask whether biophotonic energy differences could be recognized by the photons at the quantum level of their interactions/energies. I thought the answer might explain biodiversity via a link from quantum level self – other recognition to immune system recognition and to macromolecular self – other recognition. My focus has been on well-established…

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Biophysically constrained beginnings of RNA and DNA

Any anonymous participant in the discussion of: DNA may have had humble beginnings as nutrient carrier (Sep 01, 2014 by Adam Hadhazy) asks: “when are you going to keep quiet?” In a series of responses, I have explained the problem I have with honoring his request. The following excerpts from Wikipedia and other sources are loosely strung together because there is no point to providing more extensive details of biologically-based cause and effect until others accept the fact that mutations…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, mathematicians, statisticians, philosophers and theologians. replaced: Randomness and Divine Providence Supported by the John Templeton...Read more