Cryo-EM from atoms to ecosystems

Summary: I’m not going to continue repeating myself indefinitely. See: Reduced protein synthesis in schizophrenia patient-derived olfactory cells The reduced protein synthesis is a clear link from the virus-driven degradation of messenger RNA to all pathology. October 5, 2017 Lactate Metabolism in Human Lung Tumors Reported as: Study challenges long-standing concept in cancer metabolism “We were completely shocked by our findings,” said Dr. Ralph DeBerardinis, Professor at CRI, Director of CRI’s Genetic and Metabolic Disease Program, and Chief of the Division…

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Predicting who wins the 2017 Nobel Prizes (7)

Conclusion: The biggest threat to humanity is not the “Big Bang” theory of creation or the “Big Bang” theory of how life on Earth might end after an explosion of cosmic proportions. The biggest threat has always been “human idiocy.” 2017 Nobel Peace Prize Awarded to International Campaign to Abolish Nuclear Weapons “for its work to draw attention to the catastrophic humanitarian consequences of any use of nuclear weapons and for its ground-breaking efforts to achieve a treaty-based prohibition of…

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Until death: Virus-driven failure of multisensory integration (1)

Martha McClintock‘s works inspired my works. Publication of “The Scent of Eros: Mysteries of Odor Human Sexualty” (1995) led Denise Chen to study olfaction and pheromones. See for example: Encoding human sexual chemosensory cues in the orbitofrontal and fusiform cortices. Her student, Wen Zhou, returned to China and she is the senior author of Olfaction Warps Visual Time Perception. Since 1995, all accurate representations of how foraging behavior links food odors and pheromones from feedback loops to sexual reproduction and…

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Lethal virus kills 5 billion people?

Entertaining yourself to death

Summary: Food energy is required for the creation of enzymes that metabolize the food, which links the metabolism to the pheromone-controlled physiology of reproduction in species from microbes to humans via alternative splicings of pre-mRNAs, which are now called microRNAs in more than 65,000 published works. The horrid tradjedy of of yet another preventable death by suicide extends those works to preventing the cause of death of those killed by Stephen Paddock. Vegas gunman transferred $100K, set up cameras at…

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Predicting who wins the 2017 Nobel Prizes (6)

I failed to correctly predict who would win this year’s Nobel Prize in Chemistry, but there is still hope for my prediction of who will win the Nobel Peace Prize. I thought Lynn Zechiedrich would win for linking cryo-EM to the Structural diversity of supercoiled DNA Our cryo-ET, biochemical, and computational studies show the astounding versatility and dynamism of DNA depending on the degree of supercoiling. DNA simultaneously exists in a largely inactive B-form with bases tucked in and protected…

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Predicting who wins the 2017 Nobel Prizes (5)

Summary: If he was not still dead, the 1965 Nobel Laureate, Richard P. Feynman might claim that this year’s Physics Prize was awarded for “human idiocy.” Nobel Prize in Physics Awarded to LIGO Black Hole Researchers Einstein’s General Theory of Relativity, pronounced in 1916, suggested that matter and energy would warp the geometry of space-time the way a heavy sleeper sags a mattress, producing the effect we call gravity. His equations described a universe in which space and time were…

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Predicting who wins the 2017 Nobel Prizes (4)

As you wait to learn who won the 2017 Nobel Prize in Physics and in Chemistry, please consider how these recent reports will be linked from electrons to ecosystems. Every aspect must start with the creation of energy, which must link chemistry to biophysically constrained biologically based life on Earth in the context of the physiology of pheromone-controlled reproduction and Schrodinger’s claims in “What is Life? (1944). Without mention of the anti-entropic virucidal energy of sunlight, the theories of physicists…

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Thanks again for asking about DNA methylation

Re: RNA-directed DNA methylation (1996) See: From Fertilization to Adult Sexual Behavior Molecular epigenetics. It is now understood that certain genes undergo a process called “genomic or parental imprinting.” Early in embryonic development attached methyl groups become removed from most genes. Several days later, methyl groups are reattached in appropriate sites. Fascinatingly, some such genes reestablish methylation patterns based upon whether the chromosomal segment carrying the gene came from maternal or paternal chromosomes. See also: RNA-directed DNA methylation: an epigenetic…

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Predicting who wins the 2017 Nobel Prizes (3)

Summary: The unique mechanism detailed in the context of “Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression” is obviously not a unique mechanism. The mechanism exemplifies the fact that RNA-directed DNA methylation is energy-dependent and the fact that virus-driven energy theft causes the degradation of messenger RNA, which serious scientists have linked to all pathology. My failure to accurately predict who would win the 2017 Nobel Prize in Physiology or Medicine can now be placed into…

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Lethal virus kills 5 billion people?

Predicting who wins the 2017 Nobel Prizes (2)

Summary: Endogenous RNA interference is the energy-dependent epigenetic link from the physiology of pheromone-controlled reproduction to biophysically constrained viral latency. The stress-linked virus-driven degradation of messenger RNA has been linked to all pathology. Three Americans win Nobel medicine prize for body rhythm work [But they failed to link Americanism to Creationism] I predicted that Wen Zhou would win for linking the energy-dependent creation of G protein-coupled receptors to all biodiversity via olfaction and the space-time continuum in the context of…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, mathematicians, statisticians, philosophers and theologians. replaced: Randomness and Divine Providence Supported by the John Templeton...Read more