Nutrigenomics

Long-term adaptation replaces evolution (2)

The food energy-dependent “doubling up” on ‘junk DNA’ is biophysically constrained by the physiology of pheromone-controlled reproduction. The metabolism of food to species-specific pheromones links the conserved molecular mechanisms of RNA-mediated cell type differentiation in all individuals of all living genera to healthy longevity via what is known about amino acid substitutions in supercoiled DNA, which link energy-dependent changes in chirality to autophagy. Supercoiled DNA is far more dynamic than the ‘Watson-Crick’ double … Researchers have imaged in unprecedented detail the…

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Lethal virus kills 5 billion people?

Until death: Virus-driven failure of multisensory integration (2)

Summary: The virus-driven degradation of messenger RNA is clearly linked to frontotemporal dementia (FTD) by altered language, personality, behavior, cognition and motor function. What causes FTD? If the virus-driven degradation of messenger RNA causes all pathology, I would expect to find a link from microRNAs to the pathology and to the effective treatment. The social and economic burden of frontotemporal degeneration Reported as: Study reveals staggering economic burden of dementia in younger people Frontotemporal degeneration (FTD) accounts for 20 to…

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Biophysically constrained intelligence vs human idiocy

Microbes Mind Forum Research on origins, evolution, and syntheses of life How did self-organization and evolution give rise to complex, life-like systems and how can these dynamics inform our futures? How can we move beyond the Tragedy of the Commons as a necessary outcome of evolutionary dynamics to evolve toward sustainable futures, channeled by constraints that unleash innovative potential, designing multi-agent, problem-solving systems. Eshel Ben-Jacob is Professor of Physics of Complex Systems and holds the Maguy-Glass Chair in Physics at…

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Cryo-EM from atoms to ecosystems

Summary: I’m not going to continue repeating myself indefinitely. See: Reduced protein synthesis in schizophrenia patient-derived olfactory cells The reduced protein synthesis is a clear link from the virus-driven degradation of messenger RNA to all pathology. October 5, 2017 Lactate Metabolism in Human Lung Tumors Reported as: Study challenges long-standing concept in cancer metabolism “We were completely shocked by our findings,” said Dr. Ralph DeBerardinis, Professor at CRI, Director of CRI’s Genetic and Metabolic Disease Program, and Chief of the Division…

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Predicting who wins the 2017 Nobel Prizes (5)

Summary: If he was not still dead, the 1965 Nobel Laureate, Richard P. Feynman might claim that this year’s Physics Prize was awarded for “human idiocy.” Nobel Prize in Physics Awarded to LIGO Black Hole Researchers Einstein’s General Theory of Relativity, pronounced in 1916, suggested that matter and energy would warp the geometry of space-time the way a heavy sleeper sags a mattress, producing the effect we call gravity. His equations described a universe in which space and time were…

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Thanks again for asking about DNA methylation

Re: RNA-directed DNA methylation (1996) See: From Fertilization to Adult Sexual Behavior Molecular epigenetics. It is now understood that certain genes undergo a process called “genomic or parental imprinting.” Early in embryonic development attached methyl groups become removed from most genes. Several days later, methyl groups are reattached in appropriate sites. Fascinatingly, some such genes reestablish methylation patterns based upon whether the chromosomal segment carrying the gene came from maternal or paternal chromosomes. See also: RNA-directed DNA methylation: an epigenetic…

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Lethal virus kills 5 billion people?

Predicting who wins the 2017 Nobel Prizes

The Nobel Prize in Physiology or Medicine 2017 will be announced on Monday 2 October, 11:30 a.m. at the earliest. The Nobel Prize in Physics 2017 will be announced on Tuesday 3 October, 11:45 a.m. at the earliest. The Nobel Prize in Chemistry 2017 will be announced on Wednesday 4 October, 11:45 a.m. at the earliest. The Nobel Prize in Literature 2017 According to tradition, the Swedish Academy will set the date for its announcement later. The Nobel Peace Prize…

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1996-2016: Ignoring alternative splicings of pre-mRNA

Range of diseases may result when brain self-regulation goes awry, researchers say There is no such thing as self-regulation of the brain. Regulation is food energy-dependent and biophysically constrained by changes in the microRNA/messenger RNA balance. The entire range of diseases is linked from the virus-driven degradation of messenger RNA to the mutations that some theorists claim may sometimes be beneficial.The theorists the make those ridiculous claims are biologically uninformed science idiots. See for comparison: Microprocessor Recruitment to Elongating RNA…

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For God and Country

Life and death via chemical effects on photosynthesis

Summay: “…chemosignals are a promising approach both to modeling posttraumatic stress disorders in humans [36] and to searching for mehods of their treatment.” Serious scientists linked the sense of smell in bacteria from the physiology of pheromone-controlled reproduction in all living genera to our visual perception of energy and mass in the context of the space time continuum. The fact that food odors and pheromones biophysically constrain cell type differentiation in mammals was first placed into the context of [Pheromonal…

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For God and Country

Sci-Hub vs limits on the dissemination of information

The ideology of “Americanism” is not consistent with the tactics of academics and politicians that constrain release of accurate information about  biologically-based cause and effect. …Americanism is an ideology, or belief in devotion, loyalty, or allegiance to the United States of America, or to its flag, traditions, customs, culture, symbols, institutions, or form of government.[2] In the words of Theodore Roosevelt, “Americanism is a question of spirit, conviction, and purpose, not of creed or birthplace.”[3] Americanism has two different meanings.…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, mathematicians, statisticians, philosophers and theologians. replaced: Randomness and Divine Providence Supported by the John Templeton...Read more