WHO’s ignorance: From roots to shoots (1) Amino acid substitutions within or near the active site of the viral neuraminidase (NA) may affect influenza virus fitness. See: Neuraminidase inhibitor susceptibility and neuraminidase enzyme kinetics of human influenza A and B viruses circulating in Thailand in 2010–2015 The authors cite the World Health Organization’s Summary of … WHO’s ignorance: From roots to shoots (2)
For review, see: Magic traits vs Biophysical constraints across the time-space continuum of energy-dependent top-down causation. If you ignore everything known to serious scientists about the energy-dependent microRNA-mediated differentiation of all cell types in species from yeasts to mammals, you get this: Using human genetics to understand the disease impacts of testosterone in men and … Magic traits vs biophysical constraints (1)
More than 504 publications added on microRNAs during the past 10 days include some of the following details. Characteristic Dissection of Xanthomonas oryzae pv. oryzae Responsive MicroRNAs in Rice MicroRNAs (miRNAs) are crucial player in plant-pathogen interaction. If you ignore the fact that light-activated microRNA biogenesis biophysically constrains viral latency, you will fail to link … The tipping point (revisited): 97K (2)
Natural common descent driven by natural mutation (at protein, cis-regulatory & epigenetic levels) channeled by selection (natural, sexual, purifying etc), taking place over the last 4 billion years. Now what’s YOUR model, Kohl? You’ve been terrible at explaining it. — Rulon J. Downard 1/29/20 See for comparison: The pheromone darcin drives a circuit for innate … Richard Axel refutes theistic evolution
Dobzhansky (1973) linked a single amino acid substitution to all morphological, behavioral and ethnic differences in primates. Taylor et al (2015) linked two amino acid substitutions to the weekend resurrection of the ecologically adapted bacterial flagellum. The new coronavirus from Wuhan flies in the faces of biologically uninformed science idiots who represent biophysically constrained biodiversity … From Wuhan to you (3)
These cells increase in number in the aging brain, and are induced by viral infections… For the patented treatment with naturally occurring energy-dependent biophysically constrained RNA interference, see: RNA-Guided Human Genome Engineering 5. Repetitive elements or endogenous viral elements can be targeted with engineered Cas+gRNA systems in microbes, plants, animals, or human cells to reduce … Viral microRNA-mediated pathology (1)
Unraveling the Molecular Signature of Extracellular Vesicles From Endometrial-Derived Mesenchymal Stem Cells: Potential Modulatory Effects and Therapeutic Applications 12/20/19 Photosynthesis has been linked to: The biological mechanisms underlying endMSCs function have been associated to their immunomodulatory capacity (Nikoo et al., 2012), which is mediated—at least in part—by indoleamine 2,3-dioxygenase-1, cyclooxygenase-2, IL-10, and IL-27 (Peron et … MicroRNA-mediated healthy longevity (3)
1/9/20 Selected additions from my PubMed search for: microRNA Too many additions link energy-dependent changes in microRNA biogenesis from the virus-driven degradation of messenger RNA to cancer. See for example: GALE Promotes the Proliferation and Migration of Glioblastoma Cells and Is Regulated by miR-let-7i-5p Epidemiological evidence for associations between variants in microRNA or biosynthesis genes … MicroRNA-mediated healthy longevity (1)
Looking for some evolutionary biology reading in 2020? Don’t miss our “In the Light of #Evolution” series, comprising #openaccess Research, Reviews, Q&As – and more – on how an #evolutionary perspective informs all areas of #biology Looking for refutations of pseudoscientific nonsense touted by evolutionary biologists and Big Bang cosmologists? See how light-activated microRNA biogenesis … Bruce McEwen’s legacy: sympatric speciation (5)
The ever increasing number of publications that link microRNA-mediated top down causation to prevention of virus-driven pathology attests to the facts from Biology could be so much more 11/22/19 …all that hard-earned expertise can get in the way. After all, nature isn’t neatly divided along disciplinary lines, so understanding it requires an integrated way of … Bruce S. McEwen’s legacy: sympatric speciation (2)
