Pharmacogenomics

The Virus-Driven Suicide March for Science

Genetic analysis of α-synuclein 3′ untranslated region and its corresponding microRNAs in relation to Parkinson’s compared to dementia with Lewy bodies My summary: Genetic predispositions and energy-dependent microRNA biogenesis link top-down causation to the biophysically constrained transgenerational epigenetic inheritance of neuronal type-specific expression.  Energy-dependent variability in endogenous RNA interference and the SNCA gene contribute to synucleinopathies in the context of two different human pathologies. Virus-driven energy theft is linked to the regulation of the α-synuclein (SNCA) gene and the etiology…

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Viruses in pathogenic variants disrupt alternative splicings (3)

See: Viruses in pathogenic variants disrupt alternative splicings (2) See also: What is life without sunshine? Translational applications in exosome research: From biomarker discovery to biomarker discovery Exosomes—small, membrane-derived extracellular vesicles capable of carrying diverse biological cargo including proteins and microRNAs—have been found in a broad range of biological fluids and appear to be predominantly involved in cell-to-cell communication. Their natural characteristics make them uniquely suited for research and clinical applications, including as biomarkers both for diseases and for intrinsic…

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Sal Giardina: apologetics revisited

March 26, 2017 Sal Giardina wrote: “James, I appreciate your responding to my posts but I would prefer that your input would be related to the content of the post.” My reply: If you do not want people to learn how my claims are linked to yours, please tell me that you intend to continue with apologetics rather the concept of energy as information. Apologetics: … the religious discipline of defending or proving the truth of religious doctrines through systematic…

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Energy-dependent pheromone-controlled entropy (2)

See also: Energy-dependent pheromone-controlled entropy (1) Let’s make peer review scientific …peer review is often biased and inefficient. It is occasionally corrupt, sometimes a charade, an open temptation to plagiarists. Even with the best of intentions, how and whether peer review identifies high-quality science is unknown. It is, in short, unscientific. The androgynous baby-faced boy or girl pictured among those wearing pink “crotch” hats appears to representing others at the March for Women. The sign may also be representing the…

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Energy-dependent pheromone-controlled entropy (1)

Let’s make peer review scientific …peer review is often biased and inefficient. It is occasionally corrupt, sometimes a charade, an open temptation to plagiarists. Even with the best of intentions, how and whether peer review identifies high-quality science is unknown. It is, in short, unscientific. A recent PubMed search for more peer-reviewed articles that mention microRNA returned a link to this published work. “Genetic 3’UTR variation is associated with human pigmentation characteristics and sensitivity to sunlight” One energy-dependent variation links…

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Sunlight: the essence of precision medicine and world peace

See for review: The essence of precision medicine See for comparison: We not only reject Trump’s values and policies, we also renew our commitment to a future where both the church and the academy will foster attitudes and actions so that human beings and the whole of creation can thrive. We join our hearts, our minds, our voices, and our actions with those of religious believers–Christians, Jews, Muslims, and people of all faiths, as well as with secular people of…

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Charles Darwin refutes theistic evolution

Charles Darwin wrote: IF under changing conditions of life… …variability is generally related to the conditions of life… …we cannot tell how much to attribute to the accumulative action of natural selection, and how much to the definite action of the conditions of life. …during the process of modification, each has become adapted to the conditions of life… Charles Darwin placed his energy-dependent “conditions of life” first. He knew that natural selection could not occur outside the context of the…

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Stuart Kauffman refutes theistic evolution

See also: Virus-driven energy theft and premature death Biodiversity is autocatalytic (Senior author Stuart Kauffman) …it was recently shown using the RAF algorithm that the metabolic network of Escherichia coli forms a large autocatalytic set of close to 1800 reactions (Sousa et al., 2015). As far as we know, this is the first formal proof that living organisms (or at least essential parts thereof) are indeed autocatalytic sets. Reported as: “Autocatalytic biodiversity hypothesis aims to supplant Darwin’s ‘war of the…

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Natural selection for codon optimality and quantum viruses

Life is Quantum Life is energy-dependent. Energy is information. Life is not quantum except in the context of hydrogen-atom energy transfer in DNA base pairs in solution. Claims that do not also address the effects of virus-driven energy theft fail to link what is know about quantum physics from the creation of the sun to quantum biology. That is why Matti Pitkanen and other plagiarists must take my model and use it as if they knew how to link ecological…

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Energy-dependent oscillating gene networks organize life

Nascent, innate, intrinsic, and biofunctional are among the “weasel words” used by theorists who ignore the fact that all life-sustaining energy comes from the sun via hydrogen-atom transfer in DNA base pairs in solution. See how Jon Lieff continues to misrepresent that fact, by placing everything known about RNA-mediated cell type differentiation back into the context of evolution. Like all pseudoscientists, he starts with energy but fails to mention where the energy came from or where it goes when virus-driven…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, mathematicians, statisticians, philosophers and theologians. replaced: Randomness and Divine Providence Supported by the John Templeton...Read more