RNA-directed DNA methylation

From base editing to RNA editing (3)

Summary: Claims about spontaneous deamination fail to link energy-dependent changes from base editing to RNA-mediated DNA repair of damage caused by the virus-driven degradation of messenger RNA. Highly efficient RNA-guided base editing in mouse embryos 27 February 2017 They reported the use of RNA-programmable deaminases to make various animal models with single amino-acid substitutions.They linked the single amino acid substitutions from the correction of nonsense mutations in the future to the correction of genetic defects in human embryos. Reported as:…

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From base editing to RNA editing

Base Editing Now Able to Convert Adenine-Thymine to Guanine-Cytosine “Nature conveniently provides us with cytosine deaminase enzymes that operate on DNA,” Liu tells The Scientist. The creation of quantized energy in sunlight links energy as information from electrons to ecosystems via the physiology of reproduction in all living genera. The claim that “Nature” provides us with cytosine deaminase enzymes makes it seem that the enzymes emerged and automagically evolved to become purposeful and meaningful in the context of ridiculous theories…

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Loss of energy as information (1)

Summary: Koonin claims that the theories of population geneticists have replaced what he calls the just-so stories of adaptationists with testable predictions. He claims that serious scientists should attempt to falsify the ridiculous theories touted by people like him, so that the ongoing use of ridiculous mathematical models can improve our understanding of evolution. I think Koonin may be attempting to address the concerns brought forward after another biologically uninformed science idiot claimed that my refutation of neo-Darwinian pseudoscientific nonsense…

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Long-term adaptation replaces evolution (3)

Summary: Koonin thinks that serious scientists who have linked the creation of energy to all biodiversity via the physiology of pheromone-controlled reproduction in species from microbes to humans must prove that everything the serious scientists know did not occur randomly after the sun’s anti-entropic virucidal energy emerged from nothing. Other pseudoscientists have taken a step towards refuting Koonin’s moronic claim with publication of: A mammalian blood odor component serves as an approach-avoidance cue across phylum border – from flies to…

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Long-term adaptation replaces evolution (2)

The food energy-dependent “doubling up” on ‘junk DNA’ is biophysically constrained by the physiology of pheromone-controlled reproduction. The metabolism of food to species-specific pheromones links the conserved molecular mechanisms of RNA-mediated cell type differentiation in all individuals of all living genera to healthy longevity via what is known about amino acid substitutions in supercoiled DNA, which link energy-dependent changes in chirality to autophagy. Supercoiled DNA is far more dynamic than the ‘Watson-Crick’ double … Researchers have imaged in unprecedented detail the…

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Proteins “evolve” (revisited)

Complex evolutionary footprints revealed in an analysis of reused protein segments of diverse lengths Reported by Jay R. Feierman to the evolutionary psychology Yahoo Group as: Recycling at the molecular level: Protein evolution Reuse patterns in protein space reflect 3.7 billion y of evolution (58), restrained by the underlying physicochemical qualities of covalently linked amino acids. Autophagy links chirality from energy-dependent changes in electrons to ecosystems. For comparison, their claim is consistent with ridiculous misrepresentations of food energy-dependent biophysically constrained…

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For God and Country

Losers: Rediscovering an epigenetic key (2)

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity “Validation of associations reported elsewhere,” includes the detailed associations from 1996 in the molecular epigenetics section of: From fertilization to adult sexual behavior  and in my 2013 refutation of neo-Darwinian theories: Nutrient-dependent/pheromone-controlled adaptive evolution: a model  (Val370Ala is also known as rs3827760, also known as 1540T/C, 370A. It is a SNP in the ectodysplasin A receptor EDAR gene on chromosome 2.) Excerpt: Two additional recent reports link substitution…

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Virulence: Out of stock

Virulence: An Infectious Card Game This product is currently out of stock and is on backorder. For comparison, pre-orders of “Cytosis: A Cell Biology Board Game”  are being shipped this month, and the “board game” adds “depth” to what could already have been learned from the “card game.” I ordered two cases of “Cytosis.” Players start with the creation of energy and link ATP from the creation of RNA to the creation of all biophysically constrained life on Earth. Players…

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For God and Country

Faith in evolution: Paleontology as a molecular science

Keeping the faith For the last 20 years, Mary Schweitzer, a paleontologist at North Carolina State University in Raleigh, has amassed a wealth of evidence that she’s isolated protein fragments from dinosaurs as much as 80 million years old. That bucks the conventional wisdom among paleontologists who argue that proteins, which are made of chains of amino acids, can’t survive more than 1 million years or so. So far, no group other than Schweitzer and her collaborators has managed to…

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For God and Country

Energy-dependent structure and function: Until death (5)

Summary: If a player starts with evolution instead of the creation of energy that links ATP to the creation of RNA, the player is a loser. Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge. — Kalevi Kull Secular: Ancient Viruses Are Buried in Your DNA (2017) by…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, mathematicians, statisticians, philosophers and theologians. replaced: Randomness and Divine Providence Supported by the John Templeton...Read more