RNA methylation

Epigenetic effects of stress by Bruce McEwen (1)

A rendering of how changes in an electron’s motion (bottom view) alter the scattering of light (top view), as measured in a new experiment that scattered more than 500 photons of light from a single electron. Previous experiments had managed to scatter no more than a few photons at a time. Credit: Extreme Light Laboratory|University of Nebraska-Lincoln Summary: In the early 1990’s, Bruce McEwen inspired my life’s works, which link the epigenetic effects of nutrient-stress and/or social stress to the fact…

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The emergence of light as energy from a life-giving star (3)

See also: The emergence of light as energy from a life-giving star (2) A rendering of how changes in an electron’s motion (bottom view) alter the scattering of light (top view), as measured in a new experiment that scattered more than 500 photons of light from a single electron. Previous experiments had managed to scatter no more than a few photons at a time. Credit: Extreme Light Laboratory|University of Nebraska-Lincoln One billion suns: World’s brightest laser sparks new behavior in…

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The emergence of light as energy from a life-giving star (2)

Conclusion: …all experimental evidence of biophysically constrained life on Earth begins with the creation of the sun’s energy, not with a Universe that is always looking. See: The emergence of light as energy from a life-giving star June 20, 2017 Some science journalists seem to be following my blog posts so that they can attack my claims and continue to obfuscate cause and effect.  It is difficult to place their obfuscation into the context of coincidence. For example, in my…

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MicroRNAs GnRH and the failure of sex research

Summary: “The Bull Sperm MicroRNAome and the Effect of Fescue Toxicosis on Sperm MicroRNA Expression” accurately represents what is known about food energy-dependent RNA-mediated cell type differentiation in species from soil microbes to humans. MicroRNAs are not new players in the hypothalamic control of fertility and the effects of food odors and pheromones on microRNAs link energy-dependent changes in hormones to behavior. That fact was detailed two decades ago in our Hormones and Behavior review. Now see: [MicroRNAs: new players…

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CRISPR Cas9 technology refutes theistic evolution

Summary: RNA-guided human genome engineering presents a direct conflict to claims made in the context of CRISPR–Cas9 editing, which creates more mutations. The repair of mutations is nutrient energy-dependent and virus-driven energy theft is biophysically constrained by the physiology of pheromone-controlled reproduction. The unexpected mutations are examples of ignorance expressed by theorists in the claims about evolution. The theorists seem reluctant to admit to the facts about RNA-mediated cell type differentiation because it is energy-dependent, and most of them don’t…

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From E. coli to monkeys and mankind: Theories vs models (2)

Dedicated to Dr. Tom Jordan and Priscilla Jordan on the day of their retirement from the Baptist ministry, May 28, 2017. They always encouraged me to learn more about the “Laws of Biology” and link the Laws from energy as information to all biodiversity on Earth via the physiology of reproduction. See also: From E. coli to monkeys and mankind: Theories vs models High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding (5/23/127) …changes in observed association…

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Food energy-dependent epigenetic adaptation

Mechanism of transmembrane signaling by sensor histidine kinases, was reported as Scientists investigate how the sense of smell works in bacteria …the signaling and inactive states differ only very slightly at the nitrate-binding site – by 0.5-1 angstroms, which is approximately one fifth of the size of the ion itself (1 angstrom is 10-10 meters). However, when this ion binds to the sensor, it causes huge changes in the protein: The helices of different monomers begin to move in different…

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Cytosis in the light of evolution

In the Light of Evolution Excerpt 1 (with my emphasis) Evolutionary Biology bring together a collection of articles exploring how evolutionary principles applied across the spectrum of biology can shed light on a diverse range of topics from molecules to ecosystems, and with a particular emphasis on human genetics, interactions with the environment, and health and disease. Selected research articles will be included in addition to invited reviews and comment. My 2014 invited review of nutritional epigenetics was returned without…

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UV light and non-coding RNA

UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene …these events underlie a switch to expression of short mRNA isoforms and preferential use of alternative last exons in a number of genes, including ASCC3. Intriguingly, the switch between ASCC3 isoforms occurs on more than one level, in that the long mRNA isoform encodes a protein, functioning in the context of the ASCC complex and required for maintaining transcriptional suppression in the late stages of…

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Nothing evolved into all biodiversity on Earth

Ricki Lewis introduces more confusion into the question about “Wwhich came first, the chicken or the egg. She uses the evolved chicken to make chicken soup.” Did Christianity Speed Chicken Evolution? by Ricki Lewis. The selected genes encode the thyroid-stimulating hormone receptor (TSHR) and β-carotene dioxygenase 2 (BCDO2). Their DNA sequences echo positive selection: mutation changing an amino acid from the ancestral to the derived species. Ricki Lewis is a science writer with a PhD in genetics. She defined positive…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, mathematicians, statisticians, philosophers and theologians. replaced: Randomness and Divine Providence Supported by the John Templeton...Read more