histone modifications

Thanks again for asking about DNA methylation

Re: RNA-directed DNA methylation (1996) See: From Fertilization to Adult Sexual Behavior Molecular epigenetics. It is now understood that certain genes undergo a process called “genomic or parental imprinting.” Early in embryonic development attached methyl groups become removed from most genes. Several days later, methyl groups are reattached in appropriate sites. Fascinatingly, some such genes Thanks again for asking about DNA methylation

Chromatin: The structure of DNA (2)

A Genetically Encoded Probe for Live-Cell Imaging of H4K20 Monomethylation Excerpt (with my emphasis): Highlights •    A histone H4K20me1-specific live-cell probe, H4K20me1-mintbody, was developed. •    Dynamics and replication timing of Xi were visualized. •    Critical amino acids for the stability and/or folding of the mintbody were revealed. Reported as: Catching histones by the tail: A Chromatin: The structure of DNA (2)

Food supplement or licensed immunostimulant?

Glucan from Food Supplement to a Licensed Drug   Excerpt: “…β-glucan possesses a significant immunostimulating activity in a wide variety of species, including earthworms, shrimp, fish, chicken, rats, rabbits, guinea pigs, sheep, pigs, cattle, and, last but not least, humans. Based on these results, it has been concluded that β-glucan represents a type of immunostimulanting Food supplement or licensed immunostimulant?

Energy-dependent RNA methylation (6)

After I published Nutrient-dependent/pheromone-controlled adaptive evolution: a model, Lynnette Ferguson and Justin O’Sullivan invited me to submit this review of nutritional epigenetics for inclusion in a special issue of the journal “Nutrients.” Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems (April 10, 2014) Abstract: This atoms to ecosystems model of ecological adaptations links nutrient-dependent epigenetic Energy-dependent RNA methylation (6)

Epigenetic (re)programming of behavior (3)

Bipolar drug turns foraging ants into scouts Excerpt: “DNA methylation has become nearly synonymous with epigenetics,” says Brendan Hunt, an insect geneticist at the University of Georgia in Griffin. “This research brings needed attention to the importance of other epigenetics marks, like histone modifications.” “We finally have a mechanism to understand ‘nurture’ in molecular terms,” Epigenetic (re)programming of behavior (3)