hormone-organized

Polycombic ecological adaptation as a science, not a theory (2)

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Evolutionary Constraints in the β-Globin Cluster: The Signature of Purifying Selection at the δ-Globin (HBD) Locus and Its Role in Developmental Gene Regulation Conclusion: … the results here presented indicate that purifying selection is driving not only HBD evolution but also its neighbor pseudogene, HBBP1. In the light of recent advances in the characterization of … Polycombic ecological adaptation as a science, not a theory (2)

Virus-driven sex differences?

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DNA methylation on N6-adenine in mammalian embryonic stem cells Excerpt: DNA methylation is a crucial component of epigenetic regulation that controls many important aspects of mammalian biology, such as imprinting, X chromosome inactivation and tumorigenesis1, 2. My comment: Nutrient-dependent RNA-directed DNA methylation links RNA-mediated amino acid substitutions to protein folding chemistry during thermodynamic cycles of … Virus-driven sex differences?

Epigenetic (re)programming of behavior (3)

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Bipolar drug turns foraging ants into scouts Excerpt: “DNA methylation has become nearly synonymous with epigenetics,” says Brendan Hunt, an insect geneticist at the University of Georgia in Griffin. “This research brings needed attention to the importance of other epigenetics marks, like histone modifications.” “We finally have a mechanism to understand ‘nurture’ in molecular terms,” … Epigenetic (re)programming of behavior (3)

RNA-mediated theory killers (2)

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RNA-mediated theory killers… This is a continuation that will become a series that links the million dollar paradox to the $100,000 prize offered for finding the origin of information at Evolution 2.0, which obviously will be a continuation of Schrodinger’s claims and Dobzhansky’s claims along with the claims of others I have repeatedly mentioned here. … RNA-mediated theory killers (2)

RNA-mediated morphological AND behavioral phenotypes

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The New Genetics and Natural versus Artificial Genetic Modification Excerpt: In order to survive, the organism needs to engage in natural genetic modification in real time, an exquisitely precise molecular dance of life with RNA and DNA responding to and participating in “downstream” biological functions. My comment：RNA-mediated gene duplications and fixation of RNA-mediated amino acid … RNA-mediated morphological AND behavioral phenotypes

2 genes in 2 species (too expensive and too insignificant)

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Characterisation of two Neurogenin genes from the brook lamprey Lampetra planeri and their expression in the lamprey nervous system by Ricardo Lara Ramirez et al. Abstract excerpt: “Here we report the isolation of two Neurogenin genes, LpNgnA and LpNgnB, from the lamprey Lampetra planeri. Phylogenetic analyses show both genes have orthologues in other lamprey species … 2 genes in 2 species (too expensive and too insignificant)

MiRNAs methylation and ecological adaptation sans mutations

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MiRNAs methylation and ecological adaptation sans mutations  “Our 2003 Molecular and Cellular Biology paper …opened the mechanistic ‘black box’ of the developmental origins of adult disease susceptibility, and firmly placed the word, epigenetics, in the vernacular of this research field.”  — Randy Jirtle (2009) Our 1996 Hormones and Behavior paper included a section on molecular epigenetics with … MiRNAs methylation and ecological adaptation sans mutations