Eutrophication and phosphorylated biodiversity

In Chinese philosophy, yin and yang (also yin–yang or yin yang, 陰陽 yīnyáng “dark–bright”) describe how seemingly opposite or contrary forces may actually be complementary, interconnected, and interdependent in the natural world, and how they may give rise to each other as they interrelate to one another. Last night I dreamed that someone added color to this symbol and represented it as a spinning disk (in a publication from the Nature publishing group).  The specifics of the dream helped me…

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Alternative splicing: a new therapy?

Summary: All cell type differences in all individuals of all living genera have since been linked from energy-dependent changes in the microRNA/messenger RNA balance to healthy longevity, or from the virus-driven degradation of messenger RNA to all pathology via the activation of genes or via the loss of genes, which is determined by the alternative splicings. New therapy rejuvenates old cells in the lab, which now behave like young cells Splicing factors are crucial proteins that help gene perform their…

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Selfish X-linked alleles and X chromosome inactivation

From Fertilization to Adult Sexual Behavior In our section on molecular epigenetics from 1996 we wrote: Genomic-imprinting is also manifest in specific parts of the X-inactivation region’s related XIST gene. Here male- and female-specific methyl-group patterns participate in X-inactivation in females and also in the preferential inactivation of the paternal X in human placentae of female concepti (Harrison, 1989; Monk, 1995). This process indicates that tissues of the early conceptus can sense and react differentially to epigenetic sexual dimorphisms on…

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Pheromones biophysically constrain base editing and RNA editing

Summary: …they [Koonin’s group] substitute what they consider to be a plausible hypothesis. It places their observations into the context of a universal trend that is conserved in all life after the trend emerged, which was sometime before the last universal common ancestor of all extant organisms emerged and began to evolve. Social behaviour shapes hypothalamic neural ensemble representations of conspecific sex Published online 18 October 2017 The vibrational theory of olfaction for the win Published 31 October 2017 Neuronal…

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From base editing to RNA editing (5)

1) Maturity’ molecule helps adolescent brain grow up   2) Geneticists are starting to unravel evolution’s role in mental illness: Hints emerge that past environments could have influenced psychiatric disorders   Please try to link the maturity molecule to the evolution of mental illness outside the context of food energy-dependent base editing, RNA editing, RNA-mediated amino acid substitutions and the pheromone-controlled physiology of reproduction that stabilizes the organized genomes of all living genera via chromosomal rearrangements.   Then see:Oppositional COMT…

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From base editing to RNA editing (4)

Summary: To claim evolution, Koonin must link food energy from the pheromone-controlled physiology of reproduction to fixation of a beneficial mutation in the organized genome of one species that evolved into another species. Search Results for “base editing” = 82 blog posts starting with Cell-type differentiation on February 7, 2014 Search Results for “RNA editing” = 95 blog posts starting with In theory, or supported by experimental evidence? October 22, 2014 See for comparison PubMed: “base editing” (33 citations) and…

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The next reformation: 500 years too late? (3)

Historical perspective: October 31, 1517 was the first Reformation Day At the October 24, 2017 premiere of “Light Unshackled” (in Morganton, Georgia), I learned how the dramatic history of “The Reformation” was linked from the unnecessary suffering and premature death of many people to the life’s works of John Calvin, the leading French Protestant Reformer. Phillip Mills, Phillip Mills, Jr. and others helped me realize that John Calvin’s works led to an attempt by the Templeton Foundation to bastardize what…

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Cryo-EM: More than a suggestion

Cryo-EM imaging suggests how the double helix separates during replication October 23, 2017   Details in the structure not previously seen reveal how various protein subunits of the twin hexamers latch on to the double helix, via tiny loop-like structures. What are the subunits of protein? The subunits of proteins are called amino acids. I will not stop saying that cryo-EM links what is known about energy-dependent changes in the microRNA/messenger RNA balance from electrons to ecosystems via fixation of…

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Exome Sequencing Impact in Routine Care

Summary: They placed the pseudoscientific nonsense about selection for beneficial mutations into the context of positive selection for mutations, which are caused by the virus-driven degradation of messenger RNA. The mutations have been linked to all pathology. It’s as if all theorists want to become known as “biologically uninformed science idiots” via their associations with others who have touted claims about “beneficial mutations.” US Air Force Studying Impact of Exome Sequencing in Routine Care Who, among my fellow veterans, and…

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Virulence: Out of stock

Virulence: An Infectious Card Game This product is currently out of stock and is on backorder. For comparison, pre-orders of “Cytosis: A Cell Biology Board Game”  are being shipped this month, and the “board game” adds “depth” to what could already have been learned from the “card game.” I ordered two cases of “Cytosis.” Players start with the creation of energy and link ATP from the creation of RNA to the creation of all biophysically constrained life on Earth. Players…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, mathematicians, statisticians, philosophers and theologians. replaced: Randomness and Divine Providence Supported by the John Templeton...Read more