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Welcome to RNA-Mediated

A Message From J.V.Kohl:

Here you will find information that links physics, chemistry, and molecular epigenetics via RNA-mediated events such as the de novo creation of olfactory receptor genes in order to encourage a public discussion of a paradigm shift.

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Epigenetic inheritance of spatiotemporal regulation (3)

May 24, 2018
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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Summary: Wen Zhou’s group has linked the creation of anti-entropic virucidal light from the quantized energy-dependent creation of microRNAs to the food energy-dependent neuroendocrine origins of human behavior via the pheromone-controlled physiology of reproduction and fixation of RNA-mediated amino acid substitutions in species from microbes to humans. Simply put, she has linked quantum physics to quantum souls via what is known about biophysically constrained viral latency in the context of the cell biology game Cytosis and the future of biology.…

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The Social Brain of Autism

May 23, 2018
James Kohl
RNA Directed
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Perception of social interaction compresses subjective duration in an oxytocin-dependent manner “…perceived time, rather than being a faithful representation of physical time, is highly idiosyncratic and ingrained with one’s personality trait. Moreover, they suggest that oxytocin is involved in mediating time perception of social interaction, further supporting the role of oxytocin in human social cognition.” Wen Zhou’s group linked our visual perception of mass and energy to our social perception of time in the context of individual differences in how…

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Epigenetic inheritance of spatiotemporal regulation (2)

May 23, 2018
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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See: Epigenetic inheritance of spatiotemporal regulation Summary: Food energy-dependent changes in base pairs have repeatedly been linked to spatiotemporal regulation of mRNA translation via the pheromone-controlled physiology of reproduction and microRNA-mediated amino acid substitutions that stabilize organized genomes. See:  Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes One SNP rs4713668 (P=4.62 × 10−4) identified in our study, was in LD (r2=0.65) with rs3227, which is one of the three variants recently…

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Epigenetic inheritance of spatiotemporal regulation

May 22, 2018
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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Excerpt: The perception of time thus varies between people and may depend at least in part on personality. These results open up a new avenue for studying and manipulating how we process social situations. This could eventually benefit people who struggle with social interactions, such as those with autism spectrum disorders. Link opens the pdf: Olfaction Warps Visual Time Perception Concluding paragraph: In physics, space-time is warped by the distribution of mass and energy in it (Hwaking 1988). Our findings,…

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The origin of information (5,4,3,2,1)

May 21, 2018
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Human Brain, Light Energy, microRNA editing, Model Organisms, Physics, RNA Directed, RNA-directed DNA methylation, Subatomic
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Summary: These findings reveal a new GLU biosynthetic pathway, which could contribute to some of the sunlight-induced neurobehavioral changes. The claims about new biosynthetic pathways should be placed into the context of what is known about the energy-dependent origin of all pathways. Researchers may have solved origin-of-life conundrum …the conditions that produce nucleic acid precursors also create the starting materials needed to make natural amino acids and lipids. That suggests a single set of [light activated] reactions could have given…

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Cracks in The Granite Wall (1)

May 17, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News
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Researchers in Thailand linked US military service in Thailand during the time of the war in Vietnam from the time of the Korean War to denuclearization of North Korea via energy-dependent changes in the influenza B virus.   From scientific creationists in South Korea: A Single Amino Acid at the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses   They obviously know how to create a virus that would decimate human populations in North Korea and in other…

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The tipping point (revisited): 73,000 publications

May 16, 2018
James Kohl
Adaptations, Autophagy, Cytosis, Diseases & Disorders, Ecology
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Summary: The Bill and Melinda Gates Foundation appears to be funding misrepresentations of what serious scientists know about biophysically constrained viral latency, as if no one knew that the effect of virus-driven energy theft in a computer processing unit (CPU) is the same as the effect of bacteriophages on the human brain. The countdown that led scientific creationists in South Korea to force the denuclearization of North Korea started 2 years ago (today). 5, 4, 3, 2, 1 Predicting microRNA-disease…

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The eternal significance of microRNAs (10)

May 16, 2018
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, RNA Directed
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ETERNAL:  lasting or existing forever; without end or beginning. SYNONYMS everlasting, never-ending, endless, perpetual, undying, immortal, abiding, permanent, enduring, infinite, boundless, timeless IN CONTEXT (of truths, values, or questions) valid for all time; essentially unchanging EXAMPLE: eternal truths of art and life” EXAMPLE:  The Vietnam Veterans Memorial Wall is a wall of eternal significance. The parents of the architect left China before the Communist take-over. Scientific creationists from South Korea have since linked the efforts of the US Military forces…

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The eternal significance of microRNAs (9)

May 16, 2018
James Kohl
Adaptations, Alternative Splicings, biophotonics, Cytosis, Diseases & Disorders, Ecology, Model Organisms, RNA Directed
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Ancient origins of viruses discovered …many of the viruses infecting us today have ancient evolutionary histories that date back to the first vertebrates and perhaps the first animals in existence. Viruses do not have evolutionary histories. They adapt to hosts by stealing the quantized energy that is required for fixation of RNA-mediated amino acid substitutions in organized genomes. For example, a report of fixation of one amino acid substitution in the influenza B virus, forced denuclearizaton in North Korea. God-less…

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The eternal significance of microRNAs (8)

May 15, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, microRNA editing, RNA Directed, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity
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Use of definitions in attempts to explain any aspect of species-specific biophysically constrained cell type differentiation and aging has been replaced by the use of model systems of biological processes.  Biological processes can be compared to so-called “evolutionary processes” to show that only biological processes need to be considered in the context of Darwin’s “conditions of life” or answers to the the question  What is Life? Schrödinger (1944). K. L. Mettinger et al. (eds.), Exosomes, Stem Cells and MicroRNA, Advances…

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