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Welcome to RNA-Mediated

A Message From J.V.Kohl:

Here you will find information that links physics, chemistry, and molecular epigenetics via RNA-mediated events such as the de novo creation of olfactory receptor genes in order to encourage a public discussion of a paradigm shift.

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microRNA-mediated cures (1)

See first: Naturally attenuated viral endemicity (10) All effective cancer therapies and drug therapies are energy-dependent and microRNA-mediated. Princeton team disables long-targeted gene behind spread of major cancers 11/29/21 This discovery has its roots in 2004 research in which Princeton scientists identified a gene implicated in metastatic breast cancer, called metadherin, or MTDH. Prevent obfuscation of facts that link energy-dependent changes in single nucleotide polymorphisms (SNPs) in microRNAs to all effective cancer treatments via the RBP-noncoding RNA regulation network. Read:…

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Naturally attenuated viral endemicity (10)

See: Naturally attenuated viral endemicity (9) Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life” 4/25/20 links God’s Creation of energy-as-information from Peptide synthesis at the origin of life 11/13/20 to naturally attenuated viral endemicity across kingdoms via food energy-dependent pheromone-regulated genetic processes of reproduction. See for comparison: Kinematic self-replication in reconfigurable organisms This suggests other unique and useful phenotypes can be rapidly reached from wild-type organisms without selection or genetic engineering… Conclusion: Even if the behaviors…

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Naturally attenuated viral endemicity (9)

Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life” 4/25/20 links God’s Creation of energy-as-information from Peptide synthesis at the origin of life 11/13/20 to naturally attenuated viral endemicity across kingdoms via food energy-dependent pheromone-regulated genetic processes of reproduction. The facts of life have been linked from light-activated carbon fixation in microbes to pheromone-regulated reproduction in cyanobacteria and in humans via Regulation of FSH Synthesis by Differentially Expressed miR-488 in Anterior Adenohypophyseal Cells 11/15/21; From Fertilization to…

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Naturally attenuated viral endemicity (8)

See first: Naturally attenuated viral endemicity (7) “MicroRNA-101-3p Modulates Mitochondrial Metabolism via the Regulation of Complex II Assembly 11/19/21 …we describe a new role for miR-101-3p as a modulator of mitochondrial metabolism via its regulation of multiple mitochondrial processes, including mtDNA transcription and complex II biogenesis.” See also: Weeklong improved colour contrasts sensitivity after single 670 nm exposures associated with enhanced mitochondrial function 11/24/21 Exposure to long wavelength light (650–900 nm) in animals improves mitochondrial function, increasing ATP production and…

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Naturally attenuated viral endemicity (7)

Amino acid homeostasis for a Happy New Year! 12/31/14 Works by Christ et al., continue to attest to the rejuvenating power of blood. For example, in the context of epigenetic pharmacology and regenerative medicine, one protein in the blood has been linked to health via nutrient-dependent amino acid substitutions that differentiate all cell types in all individuals of all species. For comparison to what is known to all intelligent serious scientists about how energy-dependent single nucleotide polymorphisms in microRNAs alter…

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Naturally attenuated viral endemicity (6)

See first: Naturally attenuated viral endemicity (5) 11/15/21 Blog post # 1600 is based on a search for microRNA that returns 130,538 items There are now 130,965 results. This was added on 11/23/21 Insights into Health-Promoting Effects of Plant MicroRNAs: A Review The authors link God’s Creation of energy-as-information to light-activated microRNA biogenesis in plants. The signalling pathways link the ATP-dependent creation of RNA and the pheromone-regulated genetic processes of reproduction in species from cyanobacteria to humans. Naturally occurring light-activated…

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Naturally attenuated viral endemicity (5)

Blog post # 1600 is based on a search for microRNA that returns 130,538 items See: Next-gen Epigenetics to Understand Why We Age In his 11/16/21 webinar, David A. Sinclair will link God’s Creation of energy-as-information to naturally_attenuated microRNA-mediated viral_latency via the pH-dependent physiology of pheromone-regulated genetic processes in species from cyanobacteria to humans. His act of defiance will end the pseudoscientific nonsense touted by neo-Darwinian evolutionary theorists and Big Bang cosmologists. Atheists, Communists, conspiracy theorists, and Democrats may continue…

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Naturally attenuated viral endemicity (4)

Peptide synthesis at the origin of life 11/13/20 and Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20 link the ATP-dependent Creation of RNA 9/11/64 to …protection of the skin of P. azureus adults against increased O2 levels and UV exposure on land compared with aquatic environments. See: The peptide secreted at the water to land transition in a model amphibian has antioxidant effects 11/10/21 …PaT-2 is the first peptide expressed during the ontogeny of P. azureus, right before the…

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Naturally attenuated viral endemicity (3)

See first: Naturally attenuated viral endemicity (2) Conclusion: Energy-dependent changes in angstroms to ecosystems must be linked to the functional structure of supercoiled DNA via peptide synthesis at the origin  of life and single nucleotide polymorphisms (SNPs) in microRNAs. See also: Spatiotemporal regulation and roles of reproductive phasiRNAs in plants 11/11/21 …co-suppression was discovered as a pioneer silencing phenomenon of RNA interference (RNAi) in petunia in 1990… President Joe Biden’s scientific advisor, Eric Lander linked the facts about co-suppression and…

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Naturally attenuated viral endemicity (2)

It’s Veterans Day and my oath of enlistment has not expired. Therefore, I will try again to put constraints on virus-driven pathology (naturally attenuated viral endemicity) into the context of the American Legion’s motto: “For God and County” See for instance: eBook: Gene Interference This eBook explores how messenger RNA (mRNA) technology works and what other therapeutic applications it might yield. It also reviews how researchers are working to apply mRNA — and other RNA technologies — to potentially treat…

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