More than speculation: adaptive evolution in species from microbes to man
Excerpt from:ย Genetic Variation of an Odorant Receptor OR7D4 and Sensory Perception of Cooked Meat Containing Androstenone
โIt is tempting to speculate that certain ORs or variants of ORs influence dietary selection. These ORs might be selected during human evolution based on the available food source in a given habitat.โ (Lunde et al., 2012)
————————————————–
My Comment:
I addressed this speculation with my model of nutrient chemical calibration of individual survival where the nutrient chemicals are metabolized to pheromones that standardize and control reproduction and species survival (Kohl, 2012).
This is what occurs in species from microbes to man, but it is best detailed using the honeybee model organism and what is currently known about the molecular biology, which allows the epigenetic effects of nutrient chemicals and pheromones to be the primary determining factors for species survival (i.e., not random mutations).
As suggested by these authors in the quote above, nutrient chemicals establish the ecological niches, which establish the social niches. In vertebrates the social niches are linked by pheromones to neurogenic niches in the hypothalamus that alter luteinizing hormone, olfactory bulb neurogenesis and hippocampal neurogenesis, learning and memory.
Of course, because I’ve dismissed evolutionary theory that involves random mutations, and used the epigenetic effects of olfactory/pheromonal input on OR variants, which provide a clear evolutionary trail that can be followed from unicellular organisms to insects to humans, my work has been largely ignored. So, it is great to see others speculate about what I have modeled across species from microbes to man. Perhaps now evolutionary theorists, philosophers, and theologians can compare alternative comprehensive models of individual and species survival based on what’s known about current molecular biology.
References (all open access publications)
(Kohl, 2012) Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors. Socioaffective Neuroscience & Psychology, 2: 17338. https://dx.doi.org/10.3402/snp.v2i0.17338
See also: (Jones et al., 2012) The genomic basis of adaptive evolution in threespine sticklebacks. Nature, 484, 7392:55-61
Jones, F. C., Grabherr, M. G., Chan, Y. F., Russell, P., Mauceli, E., Johnson, J., et al. (2012). The genomic basis of adaptive evolution in threespine sticklebacks. Nature, 484(7392), 55-61.
Kohl, J. V. (2012). Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors. Socioaffective Neuroscience & Psychology, 2, 17338 – DOI: 17310.13402/snp.v17332i17330.17338.
Lunde, K., Egelandsdal, B. r., Skuterud, E., Mainland, J. D., Lea, T., Hersleth, M., et al. (2012). Genetic Variation of an Odorant Receptor OR7D4 and Sensory Perception of Cooked Meat Containing Androstenone. PLoS ONE, 7(5), e35259.
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< 1 MIN READ
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Non-random evolution of a “molecular handshake”
2 MIN READ
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Adaptive evolution: Genetic selection against some disorders
3 MIN READ
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Constraints on mutational drift
< 1 MIN READ
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Music to our ears and song in birds: a common sense approach
2 MIN READ
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Functional vomeronasal receptor genes in primates?
2 MIN READ
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Non-random adaptive evolution: fast forward to March 2013
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Non random adaptive evolution
< 1 MIN READ
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Random mutations theory and pervasive mosaic evolution (the brain)
2 MIN READ
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The hormone-miRNA axis, life span, and sexual orientation
3 MIN READ
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Random mutations theory and pervasive mosaic evolution (the body)
2 MIN READ
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Is there a model for that?
3 MIN READ
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One of the clearest examples of epigenetic effects
< 1 MIN READ
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The challenges of a Darwinian approach to anything
3 MIN READ
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A key mutational event? More story-telling. Olfaction modulates vision.
4 MIN READ
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A key mutational event? That’s not very likely.
3 MIN READ
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Desmond Morris Syndrome: No selective advantage
2 MIN READ
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Fatal attractions: a fear of pheromones
2 MIN READ
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Olfactory modulation of visual perception
2 MIN READ
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Genetic Influences on Epigenetically Effected Disease
2 MIN READ
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Do molecular mechanisms vary across species?
2 MIN READ
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Forum discussions: the most complained about member (866 words)
3 MIN READ
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Creation vs Evolution: Expression of a newly found gene
2 MIN READ
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The Knowing Nose: Chemical Signals Communicate Human Emotions
< 1 MIN READ
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Human Pheromones: Epigenetic Effects of Odors and Their Affects on Behavior
2 MIN READ
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Waiting “forever” for something to happen for the “first” time
2 MIN READ
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The end of random mutations theory
2 MIN READ
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Diet epigenetically effects development of the primate brain
< 1 MIN READ
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A “new” form of natural selection?
2 MIN READ
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Pheromonemotionally speaking
2 MIN READ
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Human Pheromones: theory vs models
3 MIN READ
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Human pheromones: another attempt to change the concept
3 MIN READ
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The Missing Transgenerational Epigenetic Links
2 MIN READ
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Playing with breasts (e.g, with a new THEORY of why only heterosexual men love them)
3 MIN READ
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Epigenetic effects on stochastic gene expression and evolutionary psychology
2 MIN READ
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“Just-So” stories vs scientific explanations
2 MIN READ
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Adaptive evolution or not: cone receptors in the eye vs odor receptors
2 MIN READ
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Insect to human cognition
2 MIN READ
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More complicated than 1-2-3
2 MIN READ
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Bio-CHEMICAL complexity
< 1 MIN READ
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What to do with research results: Warning!
2 MIN READ
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Mischaracterizations of adaptive evolution by psychologists and biologists
2 MIN READ
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Did we descend from lottery winners (Part 2)
2 MIN READ
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Did we descend from lottery winners or due to adaptive evolution
2 MIN READ
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ENCODE: extant vs extinct species and a clash of world views
4 MIN READ
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Domain-specific Mental modules and models for behavior
2 MIN READ
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Biological facts constrain proponents of random mutations theory
2 MIN READ
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Pheromones, Reciprocity, and Prosocial Behavior
3 MIN READ
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Envisioning, hindsight bias, plagiarism, or cheating
3 MIN READ
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Woefully ignorant politicians and popular science
2 MIN READ
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Pheromones and multicellularity
< 1 MIN READ
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Epigenetic effects on the evolution of behavior
2 MIN READ
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Human pheromones and the definition of life
2 MIN READ
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Classical (Pavlovian) conditioning vs operant conditioning (“training”)
2 MIN READ
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Pheromones and the phylogeny of operant and classical conditioning
2 MIN READ
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More bird-brained behavior
2 MIN READ
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Human pheromones are like sugar (and spice)
< 1 MIN READ
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A neuroscientific perspective on neurobiological differences in everyone
2 MIN READ
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Human pheromones and inner conflict about evolution (1102 words)
4 MIN READ
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Receptor-mediated biological cause and effect
2 MIN READ
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A detailed model of physical reality and natural selection (722 words)
3 MIN READ
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Evolution of the nervous system: conserved GnRH
< 1 MIN READ
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Aging Is Recorded in Our Genes
2 MIN READ
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Human Pheromone Facts and the Out of Africa Theory
3 MIN READ
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ecological social neurogenic niche
2 MIN READ
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A thought experiment
3 MIN READ
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Brain Activation Areas of Sexual Arousal with Olfactory Stimulation in Men
2 MIN READ
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No New Neurons for Smell?
2 MIN READ
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Bickering theorists: opinions about selfish genes and group selection
2 MIN READ
1
Human pheromones and the visual appeal of other people (Part Three)
2 MIN READ
0
Human pheromones and the visual appeal of other people (Part one)
2 MIN READ
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Human Pheromones and Consilience
2 MIN READ
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Cultural processes are biologically based
2 MIN READ
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Pattern recognition: How rational is that?
2 MIN READ
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Adam’s rib: Pheromones and the adaptive evolution of human sexuality
2 MIN READ
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Creation vs Evolution? Pre-existing genetic variation, not random mutation
2 MIN READ
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Human pheromones and your immune system
< 1 MIN READ
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No fooling; visual appeal is not determined by what we see
2 MIN READ
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A fallacious leap? Ancestral and derived traits
3 MIN READ
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Human Pheromones in Socioaffective Neuroscience & Psychology
2 MIN READ
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Pheromones and the โBruce effectโ in wild or domesticated horses and primates
2 MIN READ
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They are what they eat, and so are we
2 MIN READ
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How memory works
2 MIN READ
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History of intelligence (550 words)
2 MIN READ
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A Preoccupation With Modesty…
2 MIN READ
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Creation of different species without physical barriers (Part Two)
2 MIN READ
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Pheromones: from microbes to man
< 1 MIN READ
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The biology of behavior: Seeing more clearly
< 1 MIN READ
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Creation of different species without physical barriers (Part One)
< 1 MIN READ
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Effects of pheromones on menstrual synchrony and a gay man
2 MIN READ
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Teaching science to the religious: theories of development
2 MIN READ
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Did viruses make mammals communicate with pheromones?
2 MIN READ
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Do Pheromones Play a Role in Our Sex Lives: Scientific American
< 1 MIN READ
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Human Pheromones: 2010 Powerpoint slides and 2011 poster presentation
2 MIN READ
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Epigentics and the baby connectome
2 MIN READ
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Cookbook chemistry: food odors and hormones
< 1 MIN READ
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Epigenetics and the connectome
2 MIN READ
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Human pheromones and food odors
< 1 MIN READ
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The Perversion of Science by Evolutionary Psychologists
5 MIN READ
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Pheromones and the Evolution of Drug Resistance
< 1 MIN READ
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Human skull study causes evolutionary headache
< 1 MIN READ
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Docosahexaenoic acid and autism: praying for hope, or preying on hope
< 1 MIN READ
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Baiting evolutionary psychologists and others who damn religion
3 MIN READ
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Human pheromones provide clues to personality
< 1 MIN READ
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Show me the science!
5 MIN READ
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How pheromones work (in 57 words or more)
< 1 MIN READ
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Pheromone-enhanced behavior in sexually inexperienced females
2 MIN READ
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Cosmetics: are they useful or do they just make us feel good?
< 1 MIN READ
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Avian ‘Axe effect’ attracts attention of females and males
2 MIN READ
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The Mind’s Eyes: Mindful modeling of brain directed behavior
2 MIN READ
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Scents of Adolescence: Are you blind?
< 1 MIN READ
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Human Pheromones and the Biology of Behavior
5 MIN READ
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Human pheromones: social odors and food odors
< 1 MIN READ
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Avian recognition of human faces
< 1 MIN READ
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Human Pheromones Affect Women's Behavior
2 MIN READ
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A lesser role for olfaction and pheromones in humans?
1 MIN READ
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Creating a Myth
< 1 MIN READ
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Pheromones in birds, other mammals, and us
< 1 MIN READ
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The great pheromone myth revisited (including biological factors in the development of sexuality)
4 MIN READ
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The great pheromone myth revisited (including biological factors in the development of sexuality)
4 MIN READ
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Social selection: genetic contribution of viruses to life on earth
< 1 MIN READ
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Dogs and humans: Then and now
< 1 MIN READ
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Wikipedia comments by James V. Kohl
5 MIN READ
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Excellent new book about pheromones
< 1 MIN READ
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Study design| Psychophysics experiment | Perspective on conditioning
< 1 MIN READ
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Adrenarche and odor preferences
2 MIN READ
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For ethologists: Observation does not trump molecular biology
2 MIN READ
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Human Pheromones and The Philosophy of Science
2 MIN READ
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Genes, Hormones, and Behavior (for other scientists)
4 MIN READ
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Love at first sight: Selective breeding, pheromones, and Divine intervention
3 MIN READ
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A fundamental attribution error: Love at first sight
3 MIN READ
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Human Pheromones
< 1 MIN READ
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Pheromones and olfaction in the birds and the bees: from yeasts to you
2 MIN READ
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Debunking the myth of pheromones
< 1 MIN READ
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Tears and fears of pheromones
2 MIN READ
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Exotic Pheromones and Concentrates
2 MIN READ
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Marketing vs. the truth about human pheromones
2 MIN READ
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Human Pheromones, The Scent of Eros, and Cultural Evolution
< 1 MIN READ
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Molecular biology and social science theory
2 MIN READ
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Epigenetics, science fiction, and scientific fact
2 MIN READ
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Results: increased flirtatious behavior and self-reported attraction
2 MIN READ
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Is it what he or she sees in you, or is it your pheromones?
2 MIN READ
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Product comparisons and human pheromone sciences
3 MIN READ
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Conditioning of the human pair bond by human pheromones
< 1 MIN READ
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Conditioned sexual arousal to odor
2 MIN READ
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Scent signals
< 1 MIN READ
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Comparing visual to olfactory/pheromonal input
< 1 MIN READ
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Pheromones and signature mixtures
2 MIN READ
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Comparative biology of pheromonal communication
< 1 MIN READ
1
Food preferences and mate preferences
< 1 MIN READ
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Presentation on Human Pheromones delivered on August 3, 2010
2 MIN READ
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Sold on the human VNO?
< 1 MIN READ
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Effects of pheromones attributed to touch (in mice)
< 1 MIN READ
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How pheromones work by James V. Kohl
2 MIN READ
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Pheromones of pregnant women effect prolactin in men
< 1 MIN READ
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Another book author's comment on "The Great Pheromone Myth"
< 1 MIN READ
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Human Pheromones and Face Preferences
< 1 MIN READ
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Human Pheromones and WHR: Pure conjecture?
< 1 MIN READ
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An attempt to change the concept
< 1 MIN READ
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Luteinizing hormone, sex, and smell (18 years later)
2 MIN READ
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