Human Pheromones: Epigenetic Effects of Odors and Their Affects on Behavior
Society for the Scientific Study of Sexuality, Tampa, FL
Nov 8-11. Poster A-18 (Scheduled for presentation Nov 9)
Background:A detailed model explains how chemical ecology drives adaptive evolution via 1) ecological niche construction, 2) social niche construction, 3) neurogenic niche construction, and 4) socio-cognitive niche construction (Kohl, 2012). That model is used to exemplify the effects of olfactory/pheromonal conditioning, which alters genetically predisposed, nutrient chemical -dependent, hormone-driven mammalian behavior and choices for pheromones that control reproduction via their effects on luteinizing hormone (Kohl, 1992).
Model: In this diagrammatic representation of the model [soon to be linked here], nutrient chemicals are metabolized to pheromones that condition behavior in precisely the same way that food odors condition behavior associated with food preferences. The epigenetic effects of olfactory/pheromonal input calibrate and standardize molecular mechanisms for genetically predisposed receptor-mediated changes in intracellular signaling and stochastic gene expression in gonadotropin releasing hormone (GnRH) neurosecretory neurons of brain tissue. For example: glucose (Roland & Moenter, 2011) and pheromones alter the secretion of GnRH and luteinizing hormone (LH). Parenthetically, a form of GnRH that is also linked to sexual orientation appears to control the feedback loops of developmental processes required for nutrient chemical ingestion, movement, reproduction, and the diversification of species from microbes to man.
Additional Considerations (not shown): The honeybee is an invertebrate model of adaptively evolved social behavior. The concept that is extended is the epigenetic tweaking of immense gene networks in superorganisms that solve problems through the exchange and the selective cancellation and modification of signals. In the context of what has also been referred to as “biological embedding,” olfaction and odor receptors provide a clear evolutionary trail that can be followed from unicellular organisms to insects to humans. It is now clearer how an environmental drive evolved from that of nutrient chemical ingestion in unicellular organisms to that of socialization in insects. It is also clear that, in mammals, food odors and pheromones cause changes in hormones such as LH, which has developmental affects on sexual behavior in nutrient chemical-dependent reproductively fit individuals across species of vertebrates.
This model of systems biology represents the conservation of bottom-up organization and top-down activation via:
1.Nutrient-dependent stress-induced and social stress-induced intracellular changes in the homeostatic balance of microRNA(miRNA) and messenger RNA (mRNA);
2.Intermolecular changes in DNA (genes);
3.Non-random experience-dependent stochastic variations in de novo gene expression for odor receptors;
4.The required gene-cell-tissue-organ-organ system pathway that links sensory input directly to gene activation in neurosecretory cells of the brain;
5.The required reciprocity that links gene expression to behavior that alters gene expression (i.e., from genes to behavior and back).
Conclusions: Across species comparisons of epigenetic effects on genetically predisposed nutrient-dependent and hormone-driven invertebrate and vertebrate social and sexual behavior indicate that human pheromones also alter the development of the brain and behavior via the same molecular mechanisms. Those molecular mechanisms must be conserved across all species for adaptive evolution of the human brain and human behavior to occur (e.g., via properly timed reproductive sexual behavior of mammals). Note: In mammals, LH secretion is the measurable proxy for genetically predisposed differences in hypothalamic GnRH pulse frequency and amplitude and the downstream effects of GnRH on the HPG and HPA axes that provide feedback to the GnRH neuronal system, which is the central regulator of genetically predisposed nutrient chemical-dependent individual survival and pheromone-dependent species survival.
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No New Neurons for Smell?
2 MIN READ
0
Bickering theorists: opinions about selfish genes and group selection
2 MIN READ
1
Human pheromones: Olfaction, odor receptors, learning, memory, mood, brains and behavior
< 1 MIN READ
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A nutrient chemical and pheromone-dependent neurogenic niche
2 MIN READ
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Passing On Stress
2 MIN READ
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Human pheromone- and nutrient-dependent brain development and behavior
2 MIN READ
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Human pheromones and the visual appeal of other people (Part Three)
2 MIN READ
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Human pheromones and the visual appeal of other people (Part Two)
2 MIN READ
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Human pheromones and the visual appeal of other people (Part one)
2 MIN READ
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Human pheromones and brain development
2 MIN READ
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Human Pheromones and Consilience
2 MIN READ
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More than speculation: adaptive evolution in species from microbes to man
2 MIN READ
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Pattern recognition: How rational is that?
2 MIN READ
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Pre-existing genetic variability or random mutations: a matter of priorities and choices
2 MIN READ
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Human Pheromones and Common Scents: Plants and Perfume
< 1 MIN READ
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Creation vs Evolution? Pre-existing genetic variation, not random mutation
2 MIN READ
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Human pheromones and your immune system
< 1 MIN READ
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Human Pheromones: extremely technical representation of the concept
2 MIN READ
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A fear of pheromones (revisited)
3 MIN READ
0
A fallacious leap? Ancestral and derived traits
3 MIN READ
0
Human Pheromones in Socioaffective Neuroscience & Psychology
2 MIN READ
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Pheromones and the “Bruce effect” in wild or domesticated horses and primates
2 MIN READ
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Love is a receptor-mediated event: the pervasive influence of the late Robert L. Moss
3 MIN READ
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They are what they eat, and so are we
2 MIN READ
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How memory works
2 MIN READ
0
History of intelligence (550 words)
2 MIN READ
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A Preoccupation With Modesty…
2 MIN READ
0
Creation of different species without physical barriers (Part Two)
2 MIN READ
0
Pheromones: from microbes to man
< 1 MIN READ
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The biology of behavior: Seeing more clearly
< 1 MIN READ
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Explaining a good theory
< 1 MIN READ
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Creation of different species without physical barriers (Part One)
< 1 MIN READ
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Effects of pheromones on menstrual synchrony and a gay man
2 MIN READ
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Did viruses make mammals communicate with pheromones?
2 MIN READ
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Do Pheromones Play a Role in Our Sex Lives: Scientific American
< 1 MIN READ
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Human Pheromones: 2010 Powerpoint slides and 2011 poster presentation
2 MIN READ
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Epigentics and the baby connectome
2 MIN READ
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Cookbook chemistry: food odors and hormones
< 1 MIN READ
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Epigenetics and the connectome
2 MIN READ
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Human pheromones and food odors
< 1 MIN READ
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Misrepresentations of biologically based cause and effect:
3 MIN READ
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The Perversion of Science by Evolutionary Psychologists
5 MIN READ
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Pheromones and the Evolution of Drug Resistance
< 1 MIN READ
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Human skull study causes evolutionary headache
< 1 MIN READ
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Docosahexaenoic acid and autism: praying for hope, or preying on hope
< 1 MIN READ
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Timing is key in the proper wiring of the brain: study
2 MIN READ
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Behavioral epigenetics
2 MIN READ
0
Baiting evolutionary psychologists and others who damn religion
3 MIN READ
0
Human pheromones provide clues to personality
< 1 MIN READ
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Human Pheromones may influence brain chemistry into adulthood
< 1 MIN READ
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Human Pheromones and sex differences in brain maturation
< 1 MIN READ
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Progress in brain research (e.g., starting over)
< 1 MIN READ
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Show me the science!
5 MIN READ
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Baiting the behaviorist(s)
3 MIN READ
0
Theory versus biological facts: Mental modules and models for behavior
2 MIN READ
0
An organizing principle for our sense of smell
< 1 MIN READ
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How pheromones work (in 57 words or more)
< 1 MIN READ
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Men and women who stare at goats…
2 MIN READ
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The Sex Lives of Insects: Part III
3 MIN READ
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The Sex Lives of Insects (Part II)
3 MIN READ
0
The Sex Lives of Insects
< 1 MIN READ
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Pheromone-enhanced behavior in sexually inexperienced females
2 MIN READ
0
The “yuck” factor: aversion to social odors?
2 MIN READ
0
Avian ‘Axe effect’ attracts attention of females and males
2 MIN READ
0
The Mind’s Eyes: Mindful modeling of brain directed behavior
2 MIN READ
0
Study results: Human pheromones affect women’s behavior
< 1 MIN READ
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Human Pheromones and the Biology of Behavior
5 MIN READ
0
Human pheromones: social odors and food odors
< 1 MIN READ
0
Honeybees, food odors, and perfume
< 1 MIN READ
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Avian recognition of human faces
< 1 MIN READ
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Human Pheromones Affect Women's Behavior
2 MIN READ
0
A lesser role for olfaction and pheromones in humans?
1 MIN READ
0
Creating a Myth
< 1 MIN READ
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Study results: Human pheromones influence human behavior
2 MIN READ
0
Pheromones in birds, other mammals, and us
< 1 MIN READ
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The great pheromone myth revisited (including biological factors in the development of sexuality)
4 MIN READ
0
The great pheromone myth revisited (including biological factors in the development of sexuality)
4 MIN READ
0
Social selection: genetic contribution of viruses to life on earth
< 1 MIN READ
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Dogs and humans: Then and now
< 1 MIN READ
0
Wikipedia comments by James V. Kohl
5 MIN READ
0
Excellent new book about pheromones
< 1 MIN READ
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Study design| Psychophysics experiment | Perspective on conditioning
< 1 MIN READ
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Adrenarche and odor preferences
2 MIN READ
0
For ethologists: Observation does not trump molecular biology
2 MIN READ
0
Human Pheromones and The Philosophy of Science
2 MIN READ
0
Genes, Hormones, and Behavior (for other scientists)
4 MIN READ
0
Too many good-smelling males is not good
< 1 MIN READ
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Love at first sight: Selective breeding, pheromones, and Divine intervention
3 MIN READ
0
A fundamental attribution error: Love at first sight
3 MIN READ
0
Human Pheromones
< 1 MIN READ
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Pheromones and olfaction in the birds and the bees: from yeasts to you
2 MIN READ
0
Debunking the myth of pheromones
< 1 MIN READ
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Human pheromones in tears automagically effect testosterone
2 MIN READ
0
Tears and fears of pheromones
2 MIN READ
0
Exotic Pheromones and Concentrates
2 MIN READ
0
Marketing vs. the truth about human pheromones
2 MIN READ
0
Human Pheromones, The Scent of Eros, and Cultural Evolution
< 1 MIN READ
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Molecular biology and social science theory
2 MIN READ
0
Study Results: Human pheromones increase flirtatious behavior and ratings of attraction
2 MIN READ
0
Epigenetics, science fiction, and scientific fact
2 MIN READ
0
Results: increased flirtatious behavior and self-reported attraction
2 MIN READ
0
Is it what he or she sees in you, or is it your pheromones?
2 MIN READ
0
Product comparisons and human pheromone sciences
3 MIN READ
0
Conditioning of the human pair bond by human pheromones
< 1 MIN READ
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Human pheromones work by effecting hormones that affect behavior
2 MIN READ
0
Conditioned sexual arousal to odor
2 MIN READ
0
Scent signals
< 1 MIN READ
0
Pheromones and signature mixtures
2 MIN READ
0
Comparative biology of pheromonal communication
< 1 MIN READ
1
Food preferences and mate preferences
< 1 MIN READ
0
Presentation on Human Pheromones delivered on August 3, 2010
2 MIN READ
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American and Canadian Mensa Presentation
< 1 MIN READ
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Sold on the human VNO?
< 1 MIN READ
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Effects of pheromones attributed to touch (in mice)
< 1 MIN READ
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How pheromones work by James V. Kohl
2 MIN READ
0
Pheromones of pregnant women effect prolactin in men
< 1 MIN READ
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Another book author's comment on "The Great Pheromone Myth"
< 1 MIN READ
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The Great Pheromone Myth (opinion/review)
19 MIN READ
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An attempt to change the concept
< 1 MIN READ
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Scent of a woman: Men’s Testosterone Responses to Women's Scent
< 1 MIN READ
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Luteinizing hormone, sex, and smell (18 years later)
2 MIN READ
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