Social experiences epigenetically effect gene networks

(click to enlarge)
October 13, 2013, from Searching for the Mind with Jon Lieff, M.D.
Excerpt 1: “The gene networks of social experience are consistent through many animals.”
My comment: Not just many animals; the gene networks of social experiences must be consistent in all animals that adaptively evolved. You cannot get from microbes to man with any consistent model of cause and effect until you realize that the molecular mechanisms that enable cause and effect are conserved. Simply put, “Olfaction and odor receptors provide a clear evolutionary trail that can be followed from unicellular organisms to insects to humans.” (excerpted from: Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors)
Excerpt 2: “Signaling molecules trigger receptors on the cell surface, then a cascade to the nucleus stimulates the genes.”
My comment: The signaling molecules present in social experiences that trigger the de novo creation of these receptors and their activation are called pheromones. The production of pheromones is nutrient-dependent, and pheromones are species-specific social signals that control reproduction, which enables adaptive evolution. See: Nutrient-dependent/pheromone-controlled adaptive evolution: a model
Excerpt 3: “The response to social situations, also, alters RNA editing and transcription, changing the entire network of genetic signals, just as if it were a brain with a new circuit.”
My comment: The response to nutrients associated with food odors also alters RNA editing and transcription, which links those alterations to species-specific pheromones and the alterations in the microRNA / messenger RNA balance and the brain circuitry that enables each of us to respond differently to the challenges of nutrition (nutrient-stress) and socialization (social stress). Whether that stress is beneficial or detrimental, our responses are recorded with each experience via the ability of olfaction and the de novo creation of olfactory receptor genes that link the epigenetic “landscape” to the physical landscape of DNA in the organized genomes of species from microbes to man.
Summary: More than anyone else, Jon Lieff appears to have ‘captured the essence’ of my decades-old model. He has done this while I am ‘in prep’ with an article that explains the complex thermodynamics required for organism-level thermoregulation. In that article, which is a continuation of the draft: Nutrient-dependent / Pheromone-controlled thermodynamics and thermoregulation,
Additional considerations: I continue to add details with citations and full references to supporting published research that will enable others to follow the trail of biological facts across a continuum of adaptations driven by the epigenetic effects of olfaction and nutrition, and by the epigenetic effects of pheromones and socialization on immune system function. This continuum incorporates epigenetically altered alternative splicings and beneficial stochastic gene expression during ecological, social, neurogenic, and socio-cognitive niche construction. These 4 stages of niche construction enable our networks of genes to respond to social experiences via precisely the same molecular mechanisms that have been detailed in the honeybee model organism, which is why I used the honeybee model organism as an example of epigenetic cause and effect in: Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors.
Others will, no doubt, begin to see the importance of detailing the biological basis of cause and effect so that the details can be compared to experimentally unsubstantiated claims of mutation-initiated natural selection. Those ridiculous claims have perturbed scientific progress just as perturbed epigenetic effects on stochastic gene expression cause cancer.
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0
Dobzhansky 1973 and precision medicine (5)
3 MIN READ
0
Dobzhansky 1973 and precision medicine (4)
5 MIN READ
0
Dobzhansky 1973 and Precision Medicine (2)
5 MIN READ
0
Dobzhansky 1973 and precision medicine
6 MIN READ
0
Twisted theories and weaponized facts
3 MIN READ
0
Autophagy: from pre-mRNAs to microRNAs, enhancers, QTLs et al.
6 MIN READ
0
Mutations: the “driving force” behind human brain complexity?
6 MIN READ
0
Mutations: the "driving force" behind human brain complexity?
6 MIN READ
0
Science journalists or paid propagandists? (3)
6 MIN READ
0
Evolved patterns of brain stimulation
3 MIN READ
0
Energy-dependent hydrogen bonds in supercoiled DNA
7 MIN READ
0
Energy-dependent chirality (2)
3 MIN READ
0
Energy-dependent chirality
6 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5 MIN READ
0
Vietnam Veterans and others with glioblastoma
3 MIN READ
0
Energy-dependent sensory maps (1996-2016)
5 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016
12 MIN READ
0
Energy-dependent oscillating gene networks organize life
4 MIN READ
0
2016 obfuscated facts about energy as information
5 MIN READ
0
Dietary lutein and pheromone-controlled brain development
4 MIN READ
0
Re-inventing mutation-driven evolution
3 MIN READ
0
Bio-functional information
3 MIN READ
0
Bird-brained theorists
< 1 MIN READ
0
Expunging the distinguished public
2 MIN READ
0
Explorers who do not know what is known (2)
6 MIN READ
0
Autophagy is the antiphage defense strategy
3 MIN READ
0
Energy-dependent de novo creation and neurogenesis (2)
5 MIN READ
0
Energy-dependent de novo creation and neurogenesis
7 MIN READ
0
Theories vs facts about polycombic adaptation
3 MIN READ
0
Tasting light links energy from creation to adaptation
9 MIN READ
0
Politicized science: The demise of RNA-mediated.com?
3 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Metabolic Phenotyping Research
2 MIN READ
0
De novo gene creation: Ignoring the experimental evidence
7 MIN READ
0
Controlled amino acid treatment of all pathology
4 MIN READ
0
Energy-dependent purifying selection / autophagy (3)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (4)
2 MIN READ
0
Energy-dependent purifying selection / autophagy
2 MIN READ
0
Optogenetics: Let there be virucidal light!
2 MIN READ
0
Survivors of RNA-mediated terrorism
5 MIN READ
0
Building delicious base pairs in class. It’s elementary Watson and Crick
3 MIN READ
0
Building delicious base pairs in class. It's elementary Watson and Crick
3 MIN READ
0
RNA-mediated “repurposing” is autophagy
2 MIN READ
0
RNA-mediated "repurposing" is autophagy
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (8)
4 MIN READ
0
Energy-dependent maternal-to-zygotic transition
6 MIN READ
1
Virus-driven mutation or amino acid substitution
5 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (7)
3 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (3)
< 1 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (2)
2 MIN READ
0
From precis to pre-mRNA and proof of concept in F1, F2, F3
6 MIN READ
0
From Precis to Proof in 6000 years (2)
5 MIN READ
0
From Precis to Proof in 6000 years
9 MIN READ
0
Coulombic interactions facilitate polycombic adaptation
5 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (3)
< 1 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (2)
3 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
Polycombic ecological adaptation as a science, not a theory
3 MIN READ
0
Biological evolution as a philosophy, not a science
6 MIN READ
0
80 years of causal analysis (1936 – 2016)
11 MIN READ
0
Did evolution autophosphorylate your kinases? (3)
2 MIN READ
1
Predictable idiosyncratic evolved convergence
3 MIN READ
0
Pheromone-controlled autophagy
4 MIN READ
0
Virus-mediated hecatombic evolution
2 MIN READ
0
Hecatombic evolution via oncocers and oncohistones
9 MIN READ
0
Did evolution autophosphorylate your kinases? (2)
5 MIN READ
1
Nutrient-dependent autophagy
3 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy (2)
6 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy
3 MIN READ
0
Hypothesis free pseudoscience vs facts (5)
6 MIN READ
0
Hypothesis free pseudoscience vs facts (1)
5 MIN READ
0
The last RNA-mediated theory killer
< 1 MIN READ
0
Chromatin: The structure of DNA (2)
8 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
Unconstrained mutations, Zika virus, Kallmann’s syndrome
4 MIN READ
0
How did the innate immune system evolve?
4 MIN READ
0
Increased soil pH and nutrient availability
4 MIN READ
0
Energy-dependent cellular communication
3 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Antithetical conclusions (7)
3 MIN READ
0
Antithetical conclusions (5)
4 MIN READ
0
Antithetical conclusions (6)
3 MIN READ
0
Antithetical conclusions (4)
3 MIN READ
0
Anthetical conclusions (2)
5 MIN READ
0
Anthetical conclusions
3 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
Pseudoscientists ignore what serious scientists prove
6 MIN READ
0
GC-rich neo-Darwinian train wreck
5 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (3)
< 1 MIN READ
0
Biophysically constrained cell type differentiation
3 MIN READ
0
From angstroms to ecosystems
7 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
Q and A: Energy-dependent cell type differentiation
10 MIN READ
0
Virus-driven downsizing of the human brain
2 MIN READ
0
MicroRNAs and sexual orientation
8 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
RNA methylation
2 MIN READ
0
Model vs theory: Progress report!
8 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
Cracking the Olfactory Code?
5 MIN READ
0
Modelling life scientifically: RNA-mediated events
12 MIN READ
0
Energy-dependent RNA methylation (6)
9 MIN READ
0
Thermotolerance and longevity (2)
3 MIN READ
0
Virus-driven energy theft: definition?
5 MIN READ
0
The tipping point? 50, 000 publications (2)
2 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (5)
6 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
Wasted Templeton Funding (4)
3 MIN READ
0
Wasted Templeton Funding (3)
2 MIN READ
0
Wasted Templeton Funding (2)
2 MIN READ
0
Millions of water molecules vs years of evolution
2 MIN READ
0
Magic, Miracle, or Molecular Mechanism?
10 MIN READ
0
Ricki Lewis’ Time Machine (4)
8 MIN READ
0
Creating and/or programming the immune system
< 1 MIN READ
0
Half truths support theories without facts
4 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Jay R. Feierman: twenty years of antagonism
5 MIN READ
0
Energy dependent RNA-mediated immunity (5)
4 MIN READ
0
Energy dependent RNA-mediated immunity (4)
6 MIN READ
0
Energy-dependent RNA-mediated immunity (1)
10 MIN READ
0
Science vs semantics
4 MIN READ
0
From angstroms to ecosystems and entropy
2 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
0
Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9 MIN READ
0
The Light and Darkness of “Evolution 2.0”
11 MIN READ
0
Will modern human populations adapt to the Zika virus?
5 MIN READ
0
Models of scientific literacy
3 MIN READ
0
Neuroscience Virtual Event vs AAAS Symposium
3 MIN READ
0
Cancer: Evolution 2.0’s Blind Spot
13 MIN READ
0
Despicable fools?
4 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Virus-perturbed alternative splicings
3 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (5)
10 MIN READ
0
The unoffically uninvited
3 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs (4)
4 MIN READ
0
Juvenile hormone links atoms to ecosystems
3 MIN READ
0
Stress-induced energy-dependent DNA repair
4 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
RNA methylation, RNA-directed DNA methylation, learning and memory
3 MIN READ
0
Perry Marshall: too much information for atheist PZ Myers
3 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
Assumptions prove ignorance
5 MIN READ
0
Life history transitions and RNA-mediated survial
2 MIN READ
0
Manufacturing fossil “evidence”
4 MIN READ
0
RNA-mediated theory killers (5)
2 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs (2)
< 1 MIN READ
0
Essential pseudoscientific concepts of atheism
3 MIN READ
0
Natural cooperation and Evolution 2.0
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
0
MicroRNAs vs Red Queen hypothesis
4 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs
9 MIN READ
0
Sulfated steroids and RNA-mediated identity codes
< 1 MIN READ
0
RNA-mediated everything
4 MIN READ
0
Phenols: Laws of physics meet biology
2 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
Models are not theories (2)
2 MIN READ
0
MicroRNA-encoded behavior
7 MIN READ
0
Fossils vs cell types and the brain
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Neo-Darwinian logic is nonsense
3 MIN READ
0
700 million years of evolution?
5 MIN READ
0
Mystery machine vs model (2)
2 MIN READ
0
Checkpoint checkmate: viruses lose if conditions of life win
< 1 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Gene creation (revisited)
2 MIN READ
0
Hijacked light energy and vertebrate pathology
4 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
The creation and activation of GPCRs
4 MIN READ
0
A 5-10K comparison of design principles to evolution
3 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Nucleic acids: Stability of DNA/RNA
2 MIN READ
0
Exosomes and the RNA-mediated future of medicine (2)
< 1 MIN READ
0
New anti-entropic microbes
3 MIN READ
0
Natural selection: an anti-entropic force?
2 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Creating genes and species
3 MIN READ
0
Thermotolerance and Longevity
57 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
The “great filter” is an epigenetic trap
4 MIN READ
0
Information and communication (2)
6 MIN READ
0
Olfaction & the octopus and human genomes (2)
4 MIN READ
0
Ecological speciation vs revised evolutionary syntheses
6 MIN READ
0
The stability of organized genomes (4)
3 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
Epimutation.com: a domain of confusion
8 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
RNA-mediated terms of virus-induced en-deer-ment
2 MIN READ
0
Hematopoiesis and practopoiesis
4 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Riding the wrong direction
3 MIN READ
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
MicroRNA – controlled ecological adaptations
5 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
Unconscious affect (revisited)
2 MIN READ
0
Virus-driven death by evolutionary theory
3 MIN READ
0
Olfactory perception of genetic information
2 MIN READ
2
Is SUMOylation RNA-directed DNA methylation?
2 MIN READ
0
Amino acid substitutions are not mutations
2 MIN READ
0
“First” evidence
5 MIN READ
0
RNA-mediated development (2)
< 1 MIN READ
0
Uniquely epigenomic gene regulation
2 MIN READ
0
Living the life that randomness created? (Sarcasm alert)
3 MIN READ
0
Ignoring top-down causation
2 MIN READ
0
microRNAs, glycosylation, and genomes
4 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Viruses and the human-like microbiome
3 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
Appetite for ingesting theories (raw)
< 1 MIN READ
0
One amino acid substitution, genes, and brain activity
3 MIN READ
0
Batch effect vs epigenetic effects
3 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
Bee-birthed epigenetics and primate cell types
5 MIN READ
0
A lighting requirement for life
11 MIN READ
3
Bees and primates automagically evolve
3 MIN READ
0
Ignoring systems complexity (it’s too complicated)
3 MIN READ
0
Computing via phosphorylation and fixation
3 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Tissue type variation and expression of genes
< 1 MIN READ
0
From gut bacteria to breast milk and back
5 MIN READ
0
How to find a “holy grail” under your nose
3 MIN READ
0
MicroRNAs and the exposome
5 MIN READ
0
Epigenetics vs the fossil record
4 MIN READ
0
Thermodynamics and protein folding landscapes
2 MIN READ
0
RNA-mediated cell types and precision medicine
5 MIN READ
0
DNA Methylation and organized genomes
7 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
Nutrient-dependent RNA interference (2)
4 MIN READ
0
The Darwin Code by Greg Bear
13 MIN READ
0
Nutrient-dependent RNA interference
4 MIN READ
0
A genetic variant refutes neo-Darwinism
6 MIN READ
0
The miRNA/mRNA balance: a suboptimal strategy?
2 MIN READ
0
Nutrient-dependent microRNAs control cell types
6 MIN READ
0
MicroRNAs and memory
< 1 MIN READ
0
Too many targets for theories
3 MIN READ
0
Methylation maintains cell type differences (2)
2 MIN READ
0
Methylation maintains cell type differences
3 MIN READ
0
Creating nothing but a theory (3)
4 MIN READ
3
Creating nothing but a theory
4 MIN READ
0
Viruses and ecologically adapted animals
2 MIN READ
0
2 genes in 2 species (too expensive and too insignificant)
11 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Anti-entropic solar energy
5 MIN READ
0
Correctly modeling life on this planet
3 MIN READ
0
Correctly modeling biological energy
2 MIN READ
0
Correctly modeling ecological adaptation
4 MIN READ
0
Behavior (4): All responses are RNA-mediated in birds
4 MIN READ
0
UV-light mutations and gene loss (not gain)
5 MIN READ
0
Virus-driven origin of life
2 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
Assembling yourself: Molecular self / other recognition
4 MIN READ
0
What about birds?
5 MIN READ
0
RNA directed DNA methylation and cell types
4 MIN READ
0
Implicating microRNAs in cancer
2 MIN READ
0
Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs
2 MIN READ
0
Reverse phosphorylation
7 MIN READ
0
RNA-mediated repurposing in microbes and adaptations in primate brains
2 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
From 3-D to epigenetically-effected 4-D genome make-up
5 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
An epigenetic trap (the prequel)
5 MIN READ
0
Imagining that data historically supports evolutionary theory
7 MIN READ
0
The anti-entropic force of "Nature"
2 MIN READ
0
Nutritional epigenetics, exercise, and immune system integrity
4 MIN READ
0
What if Darwin was not still dead?
2 MIN READ
0
Atoms to ecosystems is not almost a molecular ecology
3 MIN READ
0
Epigenetic effects of viruses on cellular homeostasis (2)
2 MIN READ
0
Biological energy and a microbiome model of a light-driven time machine
3 MIN READ
0
The biologically-based origin of the mammalian placenta (2)
6 MIN READ
0
Quantum Superpositions: let there be light
4 MIN READ
0
Are viruses microRNAs? (2)
5 MIN READ
0
Sneaking up from behind
4 MIN READ
0
Physicists: Desperate Acts
16 MIN READ
0
An epigenetic trap (the sequel)
10 MIN READ
0
All of “like kind” (Part 2)
2 MIN READ
0
All of "like kind" in the (bigger) family
6 MIN READ
1
Environment epigenetically shapes the immune system
3 MIN READ
0
Beneficial microbes kill beneficial mutations
4 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
A single amino acid substitution differentiates cell types of E. coli
3 MIN READ
0
Unconstrained evolutionary innovability
4 MIN READ
0
RNA-protein interactions reveal biophysical to ecological landscapes
2 MIN READ
0
Mutagenesis: Replacing facts with theories
5 MIN READ
0
ISHE's human ethology group
2 MIN READ
0
Amino acid homeostasis for a Happy New Year!
6 MIN READ
0
From Hydra to humans vs a Lakatosian research program
4 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
Removing natural selection; reshaping the horse; adjusting evolutionary theory
4 MIN READ
0
The future of physics predicts no future for evolutionary theory
3 MIN READ
0
Model organisms: the birds and the bees
3 MIN READ
0
Chemical ecology and RNA-mediated control of DNA loops
< 1 MIN READ
0
Atoms to ecosystems: Evolutionary theory vs the coelacanth
6 MIN READ
0
Jumping back: Science or Pseudoscience?
6 MIN READ
0
Single-cell level assay of protein biosynthesis and degradation
2 MIN READ
0
Glycine and GnRH: Am I being pedantic?
4 MIN READ
0
Extensive molecular evidence vs ridiculous theories
2 MIN READ
0
Dual genomes: exposing the evolution industry
5 MIN READ
0
One test of bioenergetic health?
2 MIN READ
0
Meaningful dialogue, anonymous fools and idiot minions
4 MIN READ
0
Epigenetic pharmacology and RNA-mediated transciptional landscapes
3 MIN READ
0
RNA-mediated events and "The Theory of Everything"
4 MIN READ
0
Sackler Colloquium: Effects or AFFECTS on Behavior
2 MIN READ
0
Thermodynamic constraints and ecological adaptations sans evolution
6 MIN READ
0
Eliminating correlations from evolutionary ecology
6 MIN READ
0
RNA-mediated species specificity
2 MIN READ
0
Are mutations beneficial?
4 MIN READ
0
The key to science: experimental evidence
5 MIN READ
0
Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
0
There’s a model for that!
5 MIN READ
0
Biologists puzzled by evolved RNAs and decaying DNA
6 MIN READ
0
More than a bag of chemicals?
2 MIN READ
0
Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
0
Making sense of quotes scattered across disciplines
2 MIN READ
0
Intelligent viruses and cancers?
10 MIN READ
0
Complex behaviors of cell types in cancer
6 MIN READ
0
De novo DNA methylation?
3 MIN READ
0
We need pattern recognition, not proclamations
3 MIN READ
0
We need pattern recognition, not a prologue
6 MIN READ
0
Pharmacogenomics
3 MIN READ
0
Sexual differentiation of cell types in plants
2 MIN READ
0
A model of MHC 'evolution'
2 MIN READ
0
From deep time into real time: What evolutionary processes?
10 MIN READ
0
In theory, or supported by experimental evidence?
5 MIN READ
0
Are evolutionary theorists 'nob ends'?
5 MIN READ
2
ALPHA GENOMIX
7 MIN READ
2
No excuses: Creation and the meaning of organismal complexity
7 MIN READ
0
Nutrient-dependent gene duplication in plants (but not animals?)
4 MIN READ
0
Evolutionary theorists justify fear of the Ebola viruses
2 MIN READ
0
Evolutionary theorists and evolutionary theists live under rocks
< 1 MIN READ
0
No understanding of biodiversity
2 MIN READ
0
Understanding physical forces of ecological variation and adaptation
< 1 MIN READ
0
Eliminating evolutionary theory
3 MIN READ
0
Behavioral ecology: please continue to believe in our fantasies
3 MIN READ
0
2014 and 2004 Nobel Prize in Medicine
3 MIN READ
0
RNA-mediated events: chromosomal rearrangements and genomic rearrangements
2 MIN READ
2
RNA-mediated genetic engineering (Part 3)
< 1 MIN READ
0
RNA-mediated genetic engineering (Part 2)
3 MIN READ
0
RNA-mediated genetic engineering
2 MIN READ
0
RNA-mediated events are not a matter of faith
2 MIN READ
0
Color vision refutes the evolutionary dogma of gene duplication
4 MIN READ
0
Unassailable evidence vs assumptions
4 MIN READ
0
Forces of "Nature" limit dissemination of information
4 MIN READ
0
Genomic surveillance ends our world of RNA-mediated ecological adaptations
2 MIN READ
0
Systems biology and memory disorders
3 MIN READ
0
RNA-mediated cell type differentiation and behavior
3 MIN READ
0
Metabolism, fixation, health or neurodegerative disorder
2 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Physics denied; pseudoscientific nonsense accepted
2 MIN READ
0
Ecological variation and niche construction: 1, 2, 3
6 MIN READ
0
Epigenetically-effected metabolic shifts and ecological adaptations
3 MIN READ
0
Evolving DNA before RNA
4 MIN READ
0
Stop evolutionary theorists. Kill cancers
3 MIN READ
0
De novo gene Creation sans evolution of genes via mutations
4 MIN READ
0
Did our adapted mind evolve?
6 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Miracles are not miracles to evolutionary theorists
2 MIN READ
0
Mathematical model: microRNA and epigenetic regulation
2 MIN READ
0
Seemingly futile cycles are not thermodynamically futile
3 MIN READ
0
Do bacterial proteins evolve?
3 MIN READ
0
Probable changes in connectivity
2 MIN READ
0
New technique used in report of atomic-level ecological adaptations
3 MIN READ
0
Can epigenetic inheritance occur without concurrent changes in morphology AND behavior?
3 MIN READ
0
Memory of repression and memory of behavior (2)
< 1 MIN READ
0
Memory of repression and memory of behavior
2 MIN READ
0
Quantum physics meets Evolutionary Psychology News
2 MIN READ
0
Nutrient-dependent pheromone-controlled exercise-induced physiques
< 1 MIN READ
0
Watching and waiting for more retractions
2 MIN READ
0
RNA-mediated ecological adaptations of teeth
4 MIN READ
0
RNA-mediated species diversification from microbes to primates
3 MIN READ
0
Some neuroscientists think a mutation led to human language development
< 1 MIN READ
0
Genotype, observed phenotype, and distinctly disordered behaviors
3 MIN READ
0
Is the problem an internet echo or Feierman's ethics?
2 MIN READ
0
Behavior (3): All responses are RNA-mediated in bees
3 MIN READ
0
RNA-mediated ecological adaptation is not evolution
2 MIN READ
0
Exploding genomes and chromosomal rearrangements via RNA-mediated events
2 MIN READ
0
Behavior (2): All responses are RNA-mediated not genetically-determined
4 MIN READ
0
Behavior: The first response is RNA-mediated not genetically-determined
3 MIN READ
0
Mechanisms that are not understood increase clarity
4 MIN READ
2
Nutrient-dependent erythropoiesis and anemia
6 MIN READ
0
Evolutionary heritage or ecological adaptation? Racism versus reality
4 MIN READ
0
A relatively young branch of science called epigenetics
4 MIN READ
0
Biophysically constrained beginnings of RNA and DNA
4 MIN READ
0
Baby talk: More misrepresentations of ecological adaptations
2 MIN READ
0
Comparing divergent model organisms
2 MIN READ
1
A microRNA-mediated mechanism that is epigenetically inherited
2 MIN READ
0
Epimutations: Attacking pseudoscientific dogmas
4 MIN READ
0
Order and disorder: Ecological adaptations not mutations
6 MIN READ
0
microRNAs differentiate neuronal cell types
3 MIN READ
0
microRNAs and species relationships
3 MIN READ
0
Drunks and Monkeys: Pseudoscientific nonsense
2 MIN READ
0
The quantum biology of consciousness
3 MIN READ
0
Behavior is receptor-mediated
10 MIN READ
0
Genes and Race: Human History?
2 MIN READ
0
Soft atheism: a case for Creation
< 1 MIN READ
0
Nutrition, pheromones and cancer (2)
2 MIN READ
0
Ecologically linked adapted ants and brains
2 MIN READ
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MiRNAs methylation and ecological adaptation sans mutations
2 MIN READ
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Nutrient-dependent cooperation vs cannibalism (video)
2 MIN READ
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Cell-type differentiation
2 MIN READ
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Another powerful refutation of mutation-initiated natural selection
4 MIN READ
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Darwinian theories vs Darwin's facts
2 MIN READ
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The wrong picture of our evolution
4 MIN READ
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96 fixed amino acid substitutions, not 96 genes
6 MIN READ
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Targeting a cancer gene
2 MIN READ
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Alternative splicings (very technical)
2 MIN READ
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Pheromone-controlled thermodynamics and cancer
2 MIN READ
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Your comment is awaiting moderation
2 MIN READ
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Functional coding variants are not mutations
2 MIN READ
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Mirror neurons and microRNA: theory vs biological facts
4 MIN READ
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Understanding the role of mutations and evolution
4 MIN READ
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Alzheimer's, microRNAs, and olfaction
< 1 MIN READ
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Evolution: innovations may have non-adaptive origins (sans mutations)
2 MIN READ
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Pheromones and cancer
4 MIN READ
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Are pheromones responsible for human body odour assessment?
2 MIN READ
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Nutrient-dependent / pheromone-controlled social structure
2 MIN READ
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Random mutations: nothing adaptive in 3 billion years
< 1 MIN READ
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Hormones effect sensitivity to androsterone
2 MIN READ
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A flawed model: no tripartate synapse in the adult brain
3 MIN READ
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Evolved development of olfactory systems
2 MIN READ
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A “new” view of evolution sans mutations
< 1 MIN READ
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Epistasis as the primary factor in molecular evolution
4 MIN READ
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Epigenetics and metabolism converge with pheromone production
2 MIN READ
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Behavioral epigenetics in ecological context
2 MIN READ
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Epigenetic maintenance of transcription / neuronal migration
2 MIN READ
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Epigenetics and evolutionary success
< 1 MIN READ
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Non-random evolution of a “molecular handshake”
2 MIN READ
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Adaptive evolution: Genetic selection against some disorders
3 MIN READ
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Constraints on mutational drift
< 1 MIN READ
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Epigenetic effects underlie sexual preferences IV
< 1 MIN READ
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Music to our ears and song in birds: a common sense approach
2 MIN READ
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Thinking about what we know (or not)
2 MIN READ
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A mathematical model of phenotypic cause, effects on genes, and affects on behavior
2 MIN READ
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Functional vomeronasal receptor genes in primates?
2 MIN READ
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Non random adaptive evolution
< 1 MIN READ
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A newly discovered hypothalamic neurogenic niche in the brain
< 1 MIN READ
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Epigenetic effects underlie sexual preferences II
3 MIN READ
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Fish Odor Syndrome
< 1 MIN READ
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Is there a model for that?
3 MIN READ
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One of the clearest examples of epigenetic effects
< 1 MIN READ
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Pheromone-induced learning: a NEW model?
2 MIN READ
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Epigenetic effects underlie sexual preferences (duh, and food preferences)
2 MIN READ
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Epigenetic effects on chromatin and regulatation of gene expression (in Archaea?)
2 MIN READ
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The genetics myth meets the great pheromone myth
2 MIN READ
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The challenges of a Darwinian approach to anything
3 MIN READ
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A key mutational event? More story-telling. Olfaction modulates vision.
4 MIN READ
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A key mutational event? That’s not very likely.
3 MIN READ
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Mutated genes and accidental intelligence?
< 1 MIN READ
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The Quest for Human Pheromones by Karl Grammer
< 1 MIN READ
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Desmond Morris Syndrome: No selective advantage
2 MIN READ
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Olfactory modulation of visual perception
2 MIN READ
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Genetic Influences on Epigenetically Effected Disease
2 MIN READ
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Why we love: Helen Fisher
< 1 MIN READ
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Disorders of development: altered microRNA / messenger RNA balance
< 1 MIN READ
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Eat like a monkey; act like a monkey
2 MIN READ
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Do molecular mechanisms vary across species?
2 MIN READ
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Human Pheromones: Epigenetic Effects on Hormones and Their Affects on Behavior
3 MIN READ
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Creation vs Evolution: Expression of a newly found gene
2 MIN READ
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Evolution at work sans random mutations
2 MIN READ
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Epistasis: Epigenetic effects of nutrient chemicals and their metabolism to pheromones
< 1 MIN READ
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Sex differences in Alzheimer's and everything else
2 MIN READ
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Sex differences in Alzheimer’s and everything else
2 MIN READ
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Are human pheromones chemosignals?
2 MIN READ
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The logic of gene regulatory networks
3 MIN READ
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Human Pheromones: Epigenetic Effects of Odors and Their Affects on Behavior
2 MIN READ
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Creating new genes (and controlling diversity)
2 MIN READ
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How Species Diversify
2 MIN READ
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Epigenetic effects of viruses on cellular homeostasis
< 1 MIN READ
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The same neural mechanisms are at work in worms and humans
2 MIN READ
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Diet epigenetically effects development of the primate brain
< 1 MIN READ
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Human pheromones determine our social behavior (REJECTED)
3 MIN READ
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Human pheromones: epigenetic effects
< 1 MIN READ
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Human pheromones: another attempt to change the concept
3 MIN READ
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Human pheromones and the fusiform fooled you area for face recognition
3 MIN READ
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The Missing Transgenerational Epigenetic Links
2 MIN READ
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Society for Social Neuroscience Presentation scheduled 10/11/12
2 MIN READ
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Epigenetic effects on stochastic gene expression and evolutionary psychology
2 MIN READ
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Genetic test predicts autism risk
< 1 MIN READ
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The Ghost in Your Genes – BBC Horizon
< 1 MIN READ
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Embracing galaxy-wide, cellular, and brain complexity
2 MIN READ
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“Just-So” stories vs scientific explanations
2 MIN READ
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Adaptive evolution or not: cone receptors in the eye vs odor receptors
2 MIN READ
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Insect to human cognition
2 MIN READ
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More complicated than 1-2-3
2 MIN READ
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Docosahexaenoic acid vs. creative use of mutations in natural selection
3 MIN READ
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What to do with research results: Warning!
2 MIN READ
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Mischaracterizations of adaptive evolution by psychologists and biologists
2 MIN READ
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Human pheromones and the epigenetic effects of isolation
2 MIN READ
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Transgenerational epigenetic inheritance of sexual orientation
2 MIN READ
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Unconscious affects on incalculable genomic interactions
3 MIN READ
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Natural selection and the behavior of whole organisms
< 1 MIN READ
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Natural selection: New insights are unlikely
< 1 MIN READ
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Natural Selection and the Complexity of the Genome
2 MIN READ
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ENCODE: extant vs extinct species and a clash of world views
4 MIN READ
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Human pheromones: an epigenetic continuum from microbes to mammals
3 MIN READ
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Biological facts constrain proponents of random mutations theory
2 MIN READ
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Pheromones, Reciprocity, and Prosocial Behavior
3 MIN READ
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Is the language of God the god problem? (1530 words)
6 MIN READ
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Envisioning, hindsight bias, plagiarism, or cheating
3 MIN READ
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The Epigenetics of Drug Development and Cholesterol Levels
< 1 MIN READ
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Woefully ignorant politicians and popular science
2 MIN READ
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Human pheromones, nutrition, DNA, epigenetics (2)
2 MIN READ
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Human pheromones and autism spectrum disorders (2)
2 MIN READ
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Epigenetic alterations due to stress
< 1 MIN READ
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Epigenetic effects on the evolution of behavior
2 MIN READ
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Human pheromones and diet-mediated life-extension
< 1 MIN READ
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Copulins: Human pheromones effect physiology and affect social behavior
2 MIN READ
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Human pheromones and the definition of life
2 MIN READ
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Human pheromones and autism spectrum disorders
2 MIN READ
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Human pheromones, the social brain and simple math computations
2 MIN READ
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Chemical signaling may shed light on how the brain reacts to its environment
2 MIN READ
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Children’s healthy diets lead to healthier IQ
< 1 MIN READ
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Transgenerational epigenetic inheritance via nutrient chemicals
1 MIN READ
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Human pheromones and IQ via neurogenic and socio-cognitive niche construction
2 MIN READ
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Human pheromones, nutrition, DNA, epigenetics
2 MIN READ
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Human Pheromones: Diversity of signaling pathways and a common response
< 1 MIN READ
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Niche construction: ecological, social, neurogenic, and socio-cognitive
2 MIN READ
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Human pheromones in business strategy
< 1 MIN READ
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Is oxygen required for sensing nutrient chemicals and pheromones?
2 MIN READ
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Human Pheromones and Free Will: a response to Gazzaniga
2 MIN READ
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Flies Evolve to Count (not)
< 1 MIN READ
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Human pheromones and altruism
3 MIN READ
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Human Pheromones and Multi-level selection
< 1 MIN READ
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Nutrient mixture and memory in patients with early Alzheimer’s
< 1 MIN READ
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Human pheromones and multi-level selection
< 1 MIN READ
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Bee research, human sweet perception, human pheromones, and metabolic disorders
< 1 MIN READ
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Human pheromones and inner conflict about evolution (1102 words)
4 MIN READ
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Where is the love?
3 MIN READ
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Human pheromones and the viruses that make us
2 MIN READ
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A detailed model of physical reality and natural selection (722 words)
3 MIN READ
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Evolution of the nervous system: conserved GnRH
< 1 MIN READ
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Hacking the Genome
< 1 MIN READ
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Human Pheromones and Comparative Epigenomics
2 MIN READ
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Aging Is Recorded in Our Genes
2 MIN READ
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Human Pheromone Facts and the Out of Africa Theory
3 MIN READ
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ecological social neurogenic niche
2 MIN READ
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Smelling the difference between young and old
< 1 MIN READ
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Human pheromones and the visual appeal of other people (Part Four)
3 MIN READ
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A thought experiment
3 MIN READ
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No New Neurons for Smell?
2 MIN READ
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Bickering theorists: opinions about selfish genes and group selection
2 MIN READ
1
Human pheromones: Olfaction, odor receptors, learning, memory, mood, brains and behavior
< 1 MIN READ
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A nutrient chemical and pheromone-dependent neurogenic niche
2 MIN READ
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Passing On Stress
2 MIN READ
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Human pheromone- and nutrient-dependent brain development and behavior
2 MIN READ
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Human pheromones and the visual appeal of other people (Part Three)
2 MIN READ
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Human pheromones and the visual appeal of other people (Part Two)
2 MIN READ
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Human pheromones and the visual appeal of other people (Part one)
2 MIN READ
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Human pheromones and brain development
2 MIN READ
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Human Pheromones: The smell of the scientific universe expanding
< 1 MIN READ
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Pre-existing genetic variability or random mutations: a matter of priorities and choices
2 MIN READ
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Human Pheromones and Common Scents: Plants and Perfume
< 1 MIN READ
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Adam’s rib: Pheromones and the adaptive evolution of human sexuality
2 MIN READ
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Human pheromones and your immune system
< 1 MIN READ
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People select specific fragrances that suit their individual body odor
< 1 MIN READ
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Human Pheromones: extremely technical representation of the concept
2 MIN READ
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Human Pheromones: but No VNO; No Erox; No Human Pheromone Sciences
3 MIN READ
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A fallacious leap? Ancestral and derived traits
3 MIN READ
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Modeling odor processing in microbes, mice, and mankind
2 MIN READ
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Human Pheromones in Socioaffective Neuroscience & Psychology
2 MIN READ
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Love is a receptor-mediated event: the pervasive influence of the late Robert L. Moss
3 MIN READ
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Exercise Alters Epigenetics
2 MIN READ
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How could antibiotics alleviate symptoms of schizophrenia?
2 MIN READ
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The biology of behavior: Seeing more clearly
< 1 MIN READ
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Explaining a good theory
< 1 MIN READ
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Researchers Investigate Epigenetic Patterns In Multiple Conditions
< 1 MIN READ
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Genes not culture drive humans forward (an antithetical approach)
< 1 MIN READ
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Do Pheromones Play a Role in Our Sex Lives: Scientific American
< 1 MIN READ
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Human Pheromones: 2010 Powerpoint slides and 2011 poster presentation
2 MIN READ
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Is Love in the Air? Human Pheromones and Axillary Chemistry by George Preti
3 MIN READ
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Another Remembered Present
2 MIN READ
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Pheromones and food odors add more than just color to your world
4 MIN READ
0
Misrepresentations of biologically based cause and effect:
3 MIN READ
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Human skull study causes evolutionary headache
< 1 MIN READ
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Docosahexaenoic acid and autism: praying for hope, or preying on hope
< 1 MIN READ
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Timing is key in the proper wiring of the brain: study
2 MIN READ
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Cause and effect in biology
< 1 MIN READ
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Progress in brain research (e.g., starting over)
< 1 MIN READ
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Show me the science!
5 MIN READ
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Baiting the behaviorist(s)
3 MIN READ
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Ethics, aphrodisiacs, and pheromones
< 1 MIN READ
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Digit ratio does not predict attractiveness of body odor
< 1 MIN READ
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An organizing principle for our sense of smell
< 1 MIN READ
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Epigenetics of food odors, nutrition, and pheromones
< 1 MIN READ
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Pheromones and falling in love (circa 1974)
< 1 MIN READ
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Trust the science. Don’t trust the hype
2 MIN READ
0
Men and women who stare at goats…
2 MIN READ
0
The Sex Lives of Insects: Part III
3 MIN READ
0
The Sex Lives of Insects (Part II)
3 MIN READ
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The Sex Lives of Insects
< 1 MIN READ
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The epigenetics of food choice and mate choice
< 1 MIN READ
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Pheromones and detectable odors
2 MIN READ
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Epigenetic ‘memory’ key to nature versus nurture
< 1 MIN READ
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Avian ‘Axe effect’ attracts attention of females and males
2 MIN READ
0
Study results: Human pheromones affect women’s behavior
< 1 MIN READ
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Human Pheromones and the Biology of Behavior
5 MIN READ
0
Honeybees, food odors, and perfume
< 1 MIN READ
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Pheromones and a realistic model of sexual differentiation
3 MIN READ
0
Sniffing out your nightlife / Pheromone-infused nightclubs
< 1 MIN READ
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Erox rises from the ashes
< 1 MIN READ
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Avian recognition of human faces
< 1 MIN READ
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Human Pheromones Affect Women's Behavior
2 MIN READ
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A lesser role for olfaction and pheromones in humans?
1 MIN READ
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Creating a Myth
< 1 MIN READ
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Study results: Human pheromones influence human behavior
2 MIN READ
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Natural scent of women linked to increased testosterone and seduction
< 1 MIN READ
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Genes, Hormones, and Behavior (for other scientists)
4 MIN READ
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Too many good-smelling males is not good
< 1 MIN READ
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Human pheromones in tears automagically effect testosterone
2 MIN READ
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Human Pheromones, The Scent of Eros, and Cultural Evolution
< 1 MIN READ
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Dialogue on pheromones: Avery Gilbert / James V. Kohl
2 MIN READ
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Mammalian pheromones are not a myth
3 MIN READ
0
Study Results: Human pheromones increase flirtatious behavior and ratings of attraction
2 MIN READ
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Results: increased flirtatious behavior and self-reported attraction
2 MIN READ
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Pheromones and sexual behavior in birds
< 1 MIN READ
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American and Canadian Mensa Presentation
< 1 MIN READ
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The Great Pheromone Myth (opinion/review)
19 MIN READ
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Human Pheromones and Face Preferences
< 1 MIN READ
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Human Pheromones, DHEA and WHR
2 MIN READ
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Welcome to Pheromones.com
< 1 MIN READ
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Human Pheromones and Brain activation
2 MIN READ
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Human pheromones do not create desire . . . they enhance it!
< 1 MIN READ
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Scent of a woman: Men’s Testosterone Responses to Women's Scent
< 1 MIN READ
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Earlier evidence: pheromones influence testosterone in men
< 1 MIN READ
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