Sex differences and thermodynamics: transcription vs mutations and racism

By: James V. Kohl | Published on: February 17, 2014

Transcriptomic dissection of sexual differences in Bemisia tabaci, an invasive agricultural pest worldwide

Excerpt: “…in the near future, a study may also be focused about the Bt-tra2 splicing patterns in females with different types and densities of the bacterial symbionts.
My comments: The conserved molecular mechanisms of nutrient-dependent sex differences and thermodynamics in the metabolism of nutrients by gut bacteria to insect sex pheromones control the physiology of reproduction in all species that sexually reproduce. I have detailed that fact in my model. The integrated roles of nutrient-dependent thermodynamics of intercellular signaling, alternative splicings of pre-mRNA, stochastic gene expression and organism-level thermoregulation are exemplified with experimental evidence of biologically based cause and effect in different model organisms. I explained how the epigenetic landscape becomes the physical landscape of DNA in the organized genomes of species from microbes — to humans infected with malarial parasites (e.g., Plasmodium spp).

Temperature alters Plasmodium blocking byWolbachia

Excerpt: Based on our data it would be remarkable if the interactions between Wolbachia, the mosquito vector and human malaria parasites were unaffected by such variation [in ambient temperature].
My comment: Ambient temperature-dependent ecological adaptations to the parasite are manifested in the hemoglobin variant: hemoglobin S (the sickle cell variant). Evolutionary theorists have portrayed this variant as if it were a mutation. In their portrayal, sickle cell disease may seem to some people to be associated with skin pigmentation and other phenotypic traits that non-scientists also associate with behavioral traits. This grossly inaccurate portrayal of biologically based cause and effect by theorists has led some people to consider racial differences in the context of medical practices, which may be a beneficial consideration for those who self-identify with different groups. It has led others to consider links between mutation-driven evolution and racism associated with individuals that racists might think belong to different groups.
Please join the publishers of “Nature” who — with publication of  SCIENTIFIC REPORTS  — extend to you a warm open-access invitation to educate yourselves and join others in the 21st century (see for example: “Evolution: A View from the 21st Century”) at a time when the biological plausibility of ecological adaptations has already replaced the theory of mutation-driven evolution with experimental evidence of cause and effect such as the evidence in the two reports linked above.
“The systems view of proteins implies that they evolve by natural genetic engineering rather than by localized mutation.” — James A. Shapiro, page 97  (link opens free book pdf)  “Evolution: A View from the 21st Century” (2011)
For a contrasting misrepresentation of cause and effect, see: “Mutation-Driven Evolution” ” (1) Mutation is the source of all genetic variation on which any form of evolution is dependent. Mutation is the change of genomic structure and includes nucleotide substitution, insertion/deletion, segmental gene duplication, genomic duplication, changes in gene regulatory systems, transposition of genes, horizontal gene transfer, etc. (2) Natural selection is for saving advantageous mutations and eliminating harmful mutations. Selective advantage of the mutation is determined by the type of DNA change, and therefore natural selection is an evolutionary process initiated by mutation. It does not have any creative power in contrast to the statements made by some authors.” — Masatoshi Nei, page 196 Mutation-Driven Evolution (2013)
No experimental evidence supports the statistical misrepresentations used in the context of mutation-driven evolution, which is why I think these two articles are important.
1) Transcriptomic dissection of sexual differences in Bemisia tabaci, an invasive agricultural pest worldwide
2) Temperature alters Plasmodium blocking byWolbachia
I reiterate: They can also be viewed in the context of my model, which is briefly detailed in this 5.5 minute video and in this poster session full text here.
For more information on why open-access publications will continue to be the most important souce of information that might otherwise be academically suppressed, see:  Why I Started Publishing In Open-Access Journals, And Why You Should Too
See also: Accelerating Science Awards Program: The video features six teams of scientists whose innovative reuse of existing research enabled important advances in medical treatment and detection, ecology and science education.
One of the teams focuses on malaria.
This is a list of questionable, scholarly open-access publishers


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