A lighting requirement for life
(click to enlarge)
Some Principles of Causal Analysis in Genetics (1936)
Extract:
high frequency radiation and particles of high velocity are very important components of the environment, causing heritable changes by a process called mutation. Even if we could conduct our experiments behind 30 metres of lead the fact that mutation has a temperature coefficient is enough to show that it depends in part on energy fluctuations which are uncontrollable.
Mutations must be controlled. See also: Life on Earth – Flow of Energy and Entropy
Excerpt:
The concept of negative entropy (first introduced by E. Schrodinger – ref [2]) or information (Shannon – ref [20]) and the ability of the Biosphere to effectively extract it from the Sun’s radiation is very important for life on Earth.
My comment: Haldane bastardized Darwin’s theory via use of Hugo de Vries definition of “mutation” before Schrodinger commented on an obvious fact. Schrodinger considered the anti-entropic energy of the sun to be a source of information. Information about the epigenetic landscape is linked to the physical landscape of DNA via nutrient-dependent RNA-mediated events and cell type differentiation in all genera. A recently published journal article links the anti-entropic epigenetic effect of the sun’s biological energy to the controlled design of a membrane that is required for photosynthesis. See:
IM30 triggers membrane fusion in cyanobacteria and chloroplasts
Excerpt:
A central role of IM30 in triggering membrane fusion explains the various pleiotropic functions ascribed to IM30 in the past, mainly based on studies using higher plants, algae or cyanobacteria with decreased IM30 contents. Lipid transport24,44, vesicle budding or fission19, protein translocation and insertion29,45,46, membrane modification28,47, as well as biogenesis of photosystems21,30,48 have been ascribed to IM30.
My comment: The biogenesis of photosystems can now be compared to claims that link abiogenesis to their evolution. Biogenesis was reported as:
Excerpt: The study elucidating the role of IM30 involved biologists, chemists, biochemists, and biophysicists…
My comments: Any elucidation of facts that link the sun’s biological energy from the de novo creation of light-induced amino acids to the creation of proteins and the membrane that enables the biophysically constrained chemistry of photosynthesis must involve biologists, chemists, biochemists, and biophysicists. Otherwise, the link from RNA-directed DNA methylation and RNA-mediated amino acid substitutions to cell type differentiation in all cells of all individuals of all genera may be lost in the reporting of results from different disciplines or different research groups.
Taken separately, the findings from separate disciplines and different research groups led one cosmologist to complain “…you are continually confusing physicists with biologists. The article is about physics, not biology.”
The article was: Is cosmology having a creative crisis?
Excerpt:
The Big Bang is a story about entropy.
My comment: Entropy cannot be linked to the biological basis of life without the anti-entropic epigenetic effects of the sun. Nevertheless, I bowed out of the discussion after an apology. Clearly, the differences between most physicists and most biologists are insurmountable. Physicists cannot seem to communicate across disciplines and explain the interactions among metabolic networks and genetic networks. To them, and to many evolutionary biologists and most human ethologists, the biggest question about biologically-based cause and effect is likely to be “What about birds?”
Dobzhansky (1964) alluded to this problem with the question about birds in Biology, molecular and organismic. He wrote:
…the only worthwhile biology is molecular biology. All else is “bird watching” or “butterfly collecting.” Bird watching and butterfly collecting are occupations manifestly unworthy of serious scientists!”
Then he added a caveat.
Such pronunciamentos can be dismissed as merely ridiculous. They are, however, caricatures of opinions entertained by some intelligent and reasonable people, whose views deserve an honest and careful consideration and analysis. Science must cope with new problems that arise and devise new approaches to old problems. Some lines of research become less profitable and less exciting and others more so.”
Dobzhansky (1964) also noted that
Ingram and others found that hemoglobin S differs from A in the substitution of just a single amino acid, valine in place of glutamic acid in the beta chain of the hemoglobin molecule.
Since then, the only productive lines of research have been less profitable than those pursued by researchers whose funding comes from the evolution industry and/or the big bang cosmology industry
See, for comparison: Top-down causation: an integrating theme within and across the sciences?
Abstract excerpt:
The idea of top-down causation is intimately related to concepts of emergence; indeed, it is a key factor in strong theories of emergence.
Article conclusion:
…the papers in this Theme Issue largely are explanatory of known aspects of science—that is, they are post hoc explanations. What is crucially needed is predictions of new tests that will confirm the hypothesis that top-down causation is real, and not just an epiphenomenon. The papers by Jaeger (microbiology) and Noble (physiology) are strong steps forward in this regard. This is perhaps the area where most needs to be done, across the board in all domains. Areas where striking progress is being made in this regard are epigenetics [22] and social neuroscience [23]. These papers are in fact dealing with top-down causation: the way they provide experimental confirmation of this concept needs to be made more explicit.
My comment: The idea that the Big Bang story about entropy could be linked to the emergence of life or to any aspect of life via the papers by Jaeger (microbiology) and Noble (physiology) in the context of top-down causation via an amino acid substitution or anything else that might differentiate the cell types of all genera is absurd. Simply put, the Big Bang cosmology industry has failed to link biologically-based cause and effect from the sun’s biological energy to life on earth and to the biodiversity of morphological phenotypes and behavioral phentypes.
For comparison, the ability of biologists, chemists, biochemists, and biophysicists to link a fusion protein to the creation of the membrane that constrains the chemistry of photosynthesis links their ability to
1) start with the de novo creation of light-induced amino acids, and link it to
2) the amino acids substitutions in proteins that determine the cell types of all individuals of all genera via the physiology of reproduction.
Successful reproduction enables the fixation of the energy required for cell type replication in organized genomes. Cells and species need energy to survive. Mutations perturb protein folding, which prevents the most successful use of energy. That’s how mutations are linked to pathology.
Haldane and others linked mutations to evolution, which explains why biologists, chemists, biochemists, and biophysicists have had a difficult time Combating Evolution to Fight Disease.
Excerpt:
Molecular biology and evolutionary biology have been separate disciplines and scientific cultures: The former is mechanistic and focused on molecules; the latter is theoretical and focused on populations. However, these domains are beginning to converge in laboratories addressing molecular mechanisms that explain how evolutionary processes work, and bring these processes to bear on medical problems such as cancer and infectious disease. Each discipline can be viewed as a missing link in the other’s description of biology, and in medicine.
My comment: Focus on theory and populations has contributed very little to what is known about the conserved molecular mechanisms of biologically-based cause and effect.
See this excerpt from my 4 published comments on Combating Evolution to Fight Disease
Darwin probably anticipated the insemination of population genetics that led to the bastardization of his detailed observations in the “Modern Synthesis.” He politely insisted that ‘conditions of life’ be considered before natural selection.
In our 1996 Hormones and Behavior review we linked Darwin’s nutrient-dependent ‘conditions of life’ to RNA-mediated cell type differentiation in species from microbes to man via their pheromone-controlled physiology of reproduction. See our section on molecular epigenetics in From Fertilization to Adult Sexual Behavior. We did not specifically mention the role of nutrients, but in subsequent works, I linked our model — as have others — to the hormone-organized and hormone-activated nutrient-dependent behaviors of other species.
Understanding that behaviors do not emerge in the context of mutations is crucial to the understanding of biologically-based cause and effect that links the epigenetic landscape to the physical landscape of DNA via cell type differentiation in all cells of all individuals of all genera. Caveat, there may be exceptions if species somehow emerge outside the context of everything currently known about the biophysically constrained chemistry of RNA-mediated protein folding.
If an emerged species if found, its emergence should be studied. Until then, serious scientists have guidelines that can be incorporated into their studies of biologically-based cause and effect that has been linked to the brain and human behavior. See for example: Comparative approaches in evolutionary psychology: molecular neuroscience meets the mind
Abstract Excerpt:
Claims regarding evolved, uniquely human, psychological constructs should be constrained by the rigorous evidentiary standards that are routine in other sciences.
See also:
In the comments on this article (free registration is required), I wrote:
New data on how genetic predispositions are epigenetically linked to phenotypically distinct neuroanatomy and behaviors is provided in the honeybee model. Across-species comparisons from insects to vertebrates clearly show that the epigenetic influence of food odors and pheromones continues throughout the life of organisms that collectively survive whereas individuals do not. These comparisons also attest to the relative salience of sensory input from the rearing environment. For example, when viewed from the consistency of animal models and conditioned behaviors, food odors are obviously more important to food selection than is our visual perception of food. Animal models affirm that food odor makes food either appealing or unappealing. Animal models reaffirm that it is the pheromones of other animals that makes them either appealing or unappealing.
Socioaffective neuroscience and psychology may progress more quickly by keeping these apparent facts in mind: Olfaction and odor receptors provide a clear evolutionary trail that can be followed from unicellular organisms to insects to humans (Keller et al., 2007; Kohl, 2007; Villarreal, 2009; Vosshall, Wong, & Axel, 2000).”
— Kohl, JV (2012) Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors Socioaffective Neuroscience & Psychology 2012; 2: 17338 – DOI: 10.3402/snp.v2i0.17338
Login to the “Frontiers” site and see the comments by George Ellis:
This is absolutely correct and forms part of the larger concept that top-down causation is a key factor not just in the way the brain works but in broader contexts in biology and even physics….
See also:
George Ellis: Great links, thanks. I’m intrigued by your work on pheromones. It is just possible it might relate to the issue of primordial emotional systems…
My comment: George Ellis is the co-author of Affective Neuronal Selection: The Nature of the Primordial Emotion Systems, which is an excellent review of what we detailed in our 1996 Hormones and Behavior review article. That invited review led to more details in another invited review that was published in 2001 as Human pheromones: integrating neuroendocrinology and ethology. My group’s 2001 invited review won the same award for linking neuroendocrinology and ethology that Jack Panksepp’s group won in 2002 for publication of Comparative approaches in evolutionary psychology: molecular neuroscience meets the mind
George FR Ellis appears to understand the links from physics to the biophysically constrained chemistry of nutrient-dependent RNA-mediated amino acid substitutions. He may also understand the link from protein folding to the primordial emotional systems of flies. However, he has made it clear to me that he does not want to discuss that link. For contrast:
Flies appear to have primordial emotional systems: See: Study reveals fruit flies exhibit the building blocks of emotion.
Excerpt:
we put forth the view that emotions are a type of internal brain state with certain general properties that can exist independently of subjective, conscious feelings, which can only be studied in humans
My comment: Their view is placed into the context of an experiment that linked visual stimuli designed to mimic an overhead predator to induction of a persistent and scalable internal state of defensive arousal in flies. That keeps people focused on what they have been taught to believe is a link from visual stimuli to behavior. The results can also be placed into the context of population genetics that link the nutrient-dependent pheromone-controlled ecological adaptation of insects to human behavior.
The behavior of all genera obviously arises in the context of ecological variation. Ecological variation in the supply of nutrient energy that links all morphological and behavioral phenotypes to all others via the conserved molecular mechanisms studied by biologists, chemists, biochemists, and biophysicists. Only evolutionary theorists and Big Bang cosmologists continue to place studies by serious scientists into the context of ridiculous theories that link mutations to evolution without linking the sun’s biological energy to nutrient availability. Theoretical physicists and evolutionary theorists skip from emergence to evolution with no links at all to biologically-based cause and effect. That’s why their theories must change, like the weather.
For example, serious scientists now know:
Excerpt:
The outside of the spools are coated in molecules called methyl markers. Under certain conditions, the methyl markers flag a gene, and the section will uncoil. That gene is now exposed to messenger RNA, which picks up the code and begins the process of making proteins.
Changes in DNA with the weather do not seem to link mutations to anything except pathology. Excess sun exposure is now linked to skin cancer, for example. But see: Vitamin B3 and DNA repair. Other experimental evidence of biologically-based cause and effect also links nutrient-dependent RNA-directed DNA methylation to DNA repair from the balance of viral microRNAs and nutrient-dependent microRNAs. The balance limits virus-driven entropic elasticity and genomic entropy. For example, RNA-mediated amino acid substitutions repair DNA.
DNA repair mechanisms are linked from the de novo creation of light-induced amino acids to the RNA-mediated amino acid substitutions that stabilize nutrient-dependent protein folding in all genera during life history transitions that link the physiology of reproduction to the fixation of beneficial amino acid substitutions. The anti-entropic epigenetic effect of nutrient-dependent microRNAs control the entropic elasticity caused by viral microRNAs.
The nutrient-dependent microRNAs typically seem to prevent the viral microRNAs from causing the perturbed protein folding that links viruses to pathology. The microRNAs, for example, are responsible for RNA-mediated DNA repair and healthy longevity in the absence of nutrient stress and or social stress that virus-driven immune system changes use to contribute to diseases that are manifested during the life histories of species from honeybees to humans.
See also: Nutrient-dependent/pheromone-controlled adaptive evolution: a model.
Excerpt:
The honeybee already serves as a model organism for studying human immunity, disease resistance, allergic reaction, circadian rhythms, antibiotic resistance, the development of the brain and behavior, mental health, longevity, diseases of the X chromosome, learning and memory, as well as conditioned responses to sensory stimuli (Kohl, 2012).
Evolutionary theorists and theoretical physicists have no model organism and no model of how the Big Bang story about entropy becomes a story about ecological variation that leads to ecological adaptation via the biophysically constrained RNA-mediated chemistry of nutrient-dependent protein folding in all genera. Without a model, theorists have only their stories.
See: Scientific method: Defend the integrity of physics
Excerpt:
The imprimatur of science should be awarded only to a theory that is testable. Only then can we defend science from attack.
Revisit this claim from Panksepp et al (2002)
Claims regarding evolved, uniquely human, psychological constructs should be constrained by the rigorous evidentiary standards that are routine in other sciences.
See also: Bacteriophages isolated from chicken meat and the horizontal transfer of antimicrobial resistance genes, which was reported as:
Excerpt:
nearly half of the 50 chicken meat samples purchased from supermarkets, street markets, and butchers in Austria contained viruses that are capable of transferring antibiotic resistance genes from one bacterium to another—or from one species to another.
My comment: This links viruses and viral microRNAs from entropic elasticity to cell type differentiation via nutrient-dependent microRNAs that repair DNA damage. That is how microRNAs link the epigenetic landscape to the physical landscape of DNA via RNA-directed DNA methylation and RNA-mediated amino acid substitutions that stabilize the organized genomes of all genera.
Anyone who was taught to believe in the pseudoscientific nonsense about mutations that lead to antibiotic resistance will probably need to re-educate themselves and learn to accept biological facts that link ecological variation to ecological adaptations. Accepting ridiculous theories is no longer an option for anyone who wishes to maintain any scientific credibility.
If, instead, viruses initially got their genes from their hosts, the de novo creation of amino acids and the creation of the membrane that enables the biophysically constrained chemistry of photosynthesis and RNA-mediated cell type differentiation in all genera could have been perturbed by the ingestion of animals by other animals. A difference of a few amino acids in plant viruses and animal viruses might be all that was required to link viral microRNAs to perturbed protein folding and pathology in every generation of every animal species that ingested the cells of another animal species. That’s food for thought, literally.
In the context of thoughts about food, it is interesting to note that some researchers have been examining the link from viruses to cell type differentiation for several decades. See for example:
Gene Silencing without DNA: RNA-Mediated Cross-Protection between Viruses (1999)
The DNA-binding properties of polyomavirus large T antigen are altered by ATP and other nucleotides (1991)
See also: A dynamic evolutionary and functional landscape of plant phased small interfering RNA (May 16, 2015)
The fact that some researchers are only now beginning to understand the the links from viruses to RNA-mediated gene silencing and cell type differentiation attests to the power of evolutionists and big bang cosmologists to keep the focus on their ridiculous theories. Their theories continue to kill millions of people each year who die needlessly because the theorists have never learned how cell type differentiation occurs, which is why their ridiculous theorists do not address biologically-based cause and effect.
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Darwinian adaptation: a clear evolutionary trail?
4 MIN READ
0
Agilent technology and energy-dependent autophagy
8 MIN READ
0
Elsevier fails to support the concept of autophagy
4 MIN READ
0
From Autophagy.pro (transitions)
4 MIN READ
0
The overwhelming ignorance of sex researchers (2)
4 MIN READ
0
Energy-dependent base editing and correction of mutations (2)
9 MIN READ
0
The overwhelming ignorance of sex researchers
5 MIN READ
0
Mouse morphs and primate diversity in 50 years
7 MIN READ
0
Exposing the 2nd Law to more ridicule (1)
6 MIN READ
0
Reporting new scientific truths is not allowed in the USA (2)
6 MIN READ
0
Light activated error-free DNA repair (3)
3 MIN READ
0
Light-activated error free DNA repair (2)
8 MIN READ
0
MicroRNAs and the Cassandra syndrome (revisited)
4 MIN READ
0
A null mutation and healthy longevity?
4 MIN READ
0
Achromobacter and killer theories
2 MIN READ
0
Natural selection for racism and all pathology
6 MIN READ
0
Pheromones biophysically constrain RNA-mediated biodiversity (1)
5 MIN READ
0
The next reformation: 500 years too late? (1)
< 1 MIN READ
0
The next reformation: 500 years too late? (2)
2 MIN READ
0
Until death: Virus-driven failure of multisensory integration (3)
4 MIN READ
0
Energy-dependent structure and function: Until death (3)
3 MIN READ
0
Energy-dependent structure and function: Until death (2)
5 MIN READ
0
Energy-dependent structure and function: Until death (1)
4 MIN READ
0
Until death: Virus-driven failure of multisensory integration (1)
4 MIN READ
0
Criticisms of a validated model
9 MIN READ
0
Predicting who wins the 2017 Nobel Prizes
4 MIN READ
0
Sexual communication signals: New Insights!
10 MIN READ
0
Host-derived creation of all pathology (1 of 2)
5 MIN READ
0
Human Idiocy: The failure to link energy from electrons to ecosystems
19 MIN READ
0
Your indifference is killing you and others
5 MIN READ
0
Your indifference is killing you and others (4)
4 MIN READ
0
Robert Sapolsky’s legacy of atheistic pseudoscientific nonsense
4 MIN READ
0
Can protein folding chemistry be understood by theorists?
5 MIN READ
0
Evolutionary congruence (losers) vs ecological adaptation (winners)
3 MIN READ
0
Irreconcilable differences: food energy vs de novo assembly
2 MIN READ
0
Energy-dependent physical and biophysical constraints (10)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (8)
5 MIN READ
0
Energy-dependent physical and biophysical constraints (7)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (6)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (3)
2 MIN READ
0
Cell type assembly and the space-time continuum
2 MIN READ
0
The emergence of light as energy from a life-giving star (2)
2 MIN READ
0
God’s shrinking role in salvation (2)
5 MIN READ
0
Food energy-dependent cell type differentiation (2)
10 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models (5)
5 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (5)
4 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (3)
5 MIN READ
0
Energy as information and constrained endogenous RNA interference (4)
7 MIN READ
0
Draining the academic swamp of parasites
3 MIN READ
0
The Virus-Driven Suicide March for Science
5 MIN READ
0
Open Science: Closed to facts about microRNAs
6 MIN READ
0
Viruses in pathogenic variants disrupt alternative splicings (2)
3 MIN READ
0
Respiration-dependent endogenous RNA interference
4 MIN READ
0
Functionally interdependent editing and methylation
4 MIN READ
0
Cytosis: Biology Content
7 MIN READ
0
Harvard researchers support young earth creationism
< 1 MIN READ
0
Virulence and your UTI
2 MIN READ
0
Thinking about energy is not radical re-thinking
6 MIN READ
0
Proof: Sunlight is energy as information
< 1 MIN READ
0
Energy-dependent pheromone-controlled entropy (2)
6 MIN READ
0
Ab initio cell wall invention, emergence, and evolution (2)
8 MIN READ
0
Energy-dependent allelic imbalances, viruses, and pathology
3 MIN READ
0
Biologically uninformed biologists fight back and lose
3 MIN READ
0
Stuart Kauffman refutes theistic evolution
3 MIN READ
0
May the anti-entropic force of sunlight be with you
4 MIN READ
0
Energy is information. Objections over ruled. You’re fired!
7 MIN READ
0
Happy Darwin Day (2017)
4 MIN READ
0
Physicists: Desperate Acts (revisited)
6 MIN READ
0
Dobzhansky 1973 and precision medicine (4)
5 MIN READ
0
Science journalists or paid propagandists? (4)
6 MIN READ
0
Dobzhansky 1973 and precision medicine
6 MIN READ
0
Science journalists or paid propagandists? (2)
3 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016
12 MIN READ
0
Energy-dependent oscillating gene networks organize life
4 MIN READ
0
Dietary lutein and pheromone-controlled brain development
4 MIN READ
0
Anti-entropic virucidal energy as information
10 MIN READ
0
Bio-functional information
3 MIN READ
0
Explorers who do not know what is known (2)
6 MIN READ
0
Energy-dependent de novo creation and neurogenesis
7 MIN READ
0
Combating evolution: Battlefield medicine vs politicized science
6 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Light, behavior and autophagy, a gender-specific risk factor
4 MIN READ
0
Controlled amino acid treatment of all pathology
4 MIN READ
0
Optogenetics: Let there be virucidal light!
2 MIN READ
0
RNA-mediated “repurposing” is autophagy
2 MIN READ
0
RNA-mediated "repurposing" is autophagy
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (8)
4 MIN READ
0
Energy-dependent maternal-to-zygotic transition
6 MIN READ
1
Virus-driven mutation or amino acid substitution
5 MIN READ
0
Epigenetically effected energy-dependent fluorescence
5 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (7)
3 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (5)
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (3)
< 1 MIN READ
0
Epigenetics and autophagy vs mutations and evolution
< 1 MIN READ
0
From Precis to Proof in 6000 years (3)
2 MIN READ
0
From precis to pre-mRNA and proof of concept in F1, F2, F3
6 MIN READ
0
From Precis to Proof in 6000 years
9 MIN READ
0
Coulombic interactions facilitate polycombic adaptation
5 MIN READ
0
Top-down adaptation vs bottom-up evolution
6 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (3)
< 1 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (2)
3 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
Biological evolution as a philosophy, not a science
6 MIN READ
0
Olfactory receptor pseudo-pseudogenes
2 MIN READ
0
Did evolution autophosphorylate your kinases? (3)
2 MIN READ
1
Pheromone-controlled autophagy
4 MIN READ
0
Virus-mediated hecatombic evolution
2 MIN READ
0
Hecatombic evolution via oncocers and oncohistones
9 MIN READ
0
Nutrient-dependent autophagy
3 MIN READ
0
Life is energy-dependent task management (2)
3 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
Hypothesis free pseudoscience vs facts (5)
6 MIN READ
0
Hypothesis free pseudoscience vs facts (2)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (1)
5 MIN READ
0
Base pairs, olfaction and RNA thermometers
4 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
DNA repair via junk DNA (1)
5 MIN READ
0
Energy-dependent cellular communication
3 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Anthetical conclusions
3 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
The Origin of Information (2)
6 MIN READ
0
Did “Nature” kill Steve Jobs? (3)
10 MIN READ
0
Funding the Human Genome Project-Write
2 MIN READ
0
MicroRNAs and sexual orientation
8 MIN READ
0
RNA methylation, learning, memory and behavior,
< 1 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
RNA methylation
2 MIN READ
0
Model vs theory: Progress report!
8 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
Energy-dependent RNA methylation (8)
4 MIN READ
0
Energy-dependent RNA methylation (6)
9 MIN READ
0
Thermotolerance and longevity (2)
3 MIN READ
0
War Games: False Flag Terrorism
5 MIN READ
0
Energy-dependent biodiversity
5 MIN READ
0
The tipping point? 50, 000 publications (2)
2 MIN READ
0
Magic, Miracle, or Molecular Mechanism (3)
2 MIN READ
0
Countdown to Genetics and Genomics
< 1 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
Wasted Templeton Funding (4)
3 MIN READ
0
RNA splicing, genetic variation, and disease
2 MIN READ
0
Half truths support theories without facts
4 MIN READ
0
Ricki Lewis’ Time Machine (3)
5 MIN READ
0
Creating nutrient-dependent life with enough genes to survive
3 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Energy-dependent purpose vs teleophobic telorexia
12 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Do not miss the misrepresentations
2 MIN READ
0
Energy dependent RNA-mediated immunity (5)
4 MIN READ
0
Energy dependent RNA-mediated immunity (4)
6 MIN READ
0
Energy dependent RNA-mediated immunity (3)
8 MIN READ
0
Energy dependent RNA-mediated immunity (2)
10 MIN READ
0
RNA-mediated DNA modifications
5 MIN READ
0
The toxic river of neo-Darwinian pseudoscience
3 MIN READ
0
Science vs semantics
4 MIN READ
0
From angstroms to ecosystems and entropy
2 MIN READ
0
Bacteria see the light and they adapt (2)
5 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands (2)
3 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
0
Bringing RNA back to epigenetics (20 years later)
11 MIN READ
0
Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9 MIN READ
0
Nutrient-dependent RNA-mediated cause and effect
3 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA
2 MIN READ
0
Bacteria see the light and they adapt
7 MIN READ
0
The Light and Darkness of “Evolution 2.0”
11 MIN READ
0
Will modern human populations adapt to the Zika virus?
5 MIN READ
0
Models of scientific literacy
3 MIN READ
0
Organic Compounds and the Miracle of Smell and Taste
7 MIN READ
0
Cancer: Evolution 2.0’s Blind Spot
13 MIN READ
0
Despicable fools?
4 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Virus-perturbed alternative splicings
3 MIN READ
0
Cytogenetic approaches link biosystems to ecosystems
3 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (5)
10 MIN READ
0
Brain evolution?
< 1 MIN READ
0
Origin and evolution of the genetic code
2 MIN READ
0
Center stage RNA-mediated events (since 1996)
3 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Ecological law, cooperation, and DNA repair
4 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
Amino acid substitutions, stress, and human behavior
3 MIN READ
0
RNA-mediated theory killers (11) (12) (13) (14) (15)
7 MIN READ
0
Finding peace and π in the light of H bond energy (2)
8 MIN READ
0
MicroRNA-mediated RNA epigenetics
2 MIN READ
0
RNA methylation, RNA-directed DNA methylation, learning and memory
3 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Epigenetic (re)programming of behavior (3)
5 MIN READ
0
Assumptions prove ignorance
5 MIN READ
0
Neo-Darwinian sink testing
2 MIN READ
0
NORAD: air defense and defense against genomic entropy
7 MIN READ
0
Life history transitions and RNA-mediated survial
2 MIN READ
0
Did Brain Atrophy Evolve?
2 MIN READ
0
Did Dobzhansky see the UV light of creation?
10 MIN READ
0
RNA-mediated theory killers (6) (7) (8) (9) (10)
5 MIN READ
0
Does metabolism link beneficial mutations to cancer?
10 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs (3)
3 MIN READ
0
Manufacturing fossil “evidence”
4 MIN READ
0
RNA-mediated theory killers (3)
7 MIN READ
0
Essential pseudoscientific concepts of atheism
3 MIN READ
0
RNA-mediated theory killers (2)
8 MIN READ
0
RNA-mediated theory killers
6 MIN READ
0
Natural cooperation and Evolution 2.0
6 MIN READ
0
A million dollar paradox?
2 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (4)
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (5)
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
0
Teaching the biologically uninformed
3 MIN READ
0
Rivals cast doubt on facts about HGT
2 MIN READ
0
Innovative Neurotechnologies Link Sunlight to Precision Medicine
4 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs
9 MIN READ
0
The Sherlock lab: Beneficial mutations
5 MIN READ
0
Neo-Darwinism vs the neocortex
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair
2 MIN READ
0
Organization of biological sequences
2 MIN READ
0
Plasma created by sunlight and RNA–mediated epigenetic heredity
2 MIN READ
0
Positive feedback loops and epigenetic traps
2 MIN READ
0
Behavioral Immune System model
4 MIN READ
0
Stress-perturbed mitochondrial dysfunction
4 MIN READ
0
Understanding cell type differentiation
3 MIN READ
0
Let there be anti-entropic light (3)
6 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Neuroplasticity
4 MIN READ
0
Sensationalizing no new mechanism
2 MIN READ
0
Cell type differentiation: atoms to ecosystems
2 MIN READ
0
Too complex for the Complex Biological Systems Alliance
4 MIN READ
0
Rediscovering quantum behavior
2 MIN READ
0
From dust to genomic entropy?
3 MIN READ
0
Virus, transposon and plasmid evolution
< 1 MIN READ
0
Models are not theories (2)
2 MIN READ
0
Models are not theories (1)
2 MIN READ
0
Fossils vs cell types and the brain
3 MIN READ
0
Can veterans and other prisoners escape pseudoscience?
2 MIN READ
0
eQTLs and ecological adaptation
< 1 MIN READ
0
RNA central and RNA-mediated.com
6 MIN READ
0
Ecological speciation. Get it, theorists?
< 1 MIN READ
0
Designing, engineering, and protecting biodiversity
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Controled Stem Cell Expansion
3 MIN READ
0
Neo-Darwinian logic is nonsense
3 MIN READ
0
FREE* SAMPLE: Histone modification
4 MIN READ
0
700 million years of evolution?
5 MIN READ
0
Biophysically constrained or unconstrained?
2 MIN READ
0
Mutated mitochondrial genes vs Supercoiled DNA
2 MIN READ
0
RNA-mediated retrotransposon-mediated biodiversity
3 MIN READ
0
Mystery machine vs model (3)
2 MIN READ
0
Mystery machine vs model (2)
2 MIN READ
0
Mystery machine vs model
2 MIN READ
0
Mystery machine vs medical intelligence
2 MIN READ
0
The Current State of Neuroscience
3 MIN READ
0
Cancer: forward and reverse
2 MIN READ
0
Energy and evolution: another opinion?
2 MIN READ
0
Bird watchers and RNAs in cancers
2 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Microbes to humans 2015 Nobel Prize
2 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Viruses come alive: Tree of life pseudoscience
6 MIN READ
0
Theorists have not seen the light (2)
3 MIN READ
0
Hijacked light energy and vertebrate pathology
4 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
A 5-10K comparison of design principles to evolution
3 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Pathology: Eating and breathing viruses
2 MIN READ
0
Nucleic acids: Stability of DNA/RNA
2 MIN READ
0
Exosomes and the RNA-mediated future of medicine (3)
2 MIN READ
0
Exosomes and the RNA-mediated future of medicine (2)
< 1 MIN READ
0
Exosomes and the RNA-mediated future of medicine
5 MIN READ
0
Multi-omic analysis features (SNPs, miRNA)
3 MIN READ
0
Anti-entropic effects on the origin of life
< 1 MIN READ
0
Somatic hypermutation vs RNA-mediated events
2 MIN READ
0
From fertilization to RNA-mediated events and back
2 MIN READ
0
Phytochemical link from the sun to cell types
2 MIN READ
0
Metabolic competition and cancer
2 MIN READ
0
Natural selection: an anti-entropic force?
2 MIN READ
0
Genome sequencing, cadherins, and quantum consciousness
6 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Creating genes and species
3 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
A “new” code enables ecological adaptation
4 MIN READ
0
Thermotolerance and Longevity
57 MIN READ
0
RNA-mediated permanent symbioses
11 MIN READ
0
Is life the balance between quantum and classical physics?
3 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
RNA-mediated X chromosome inactivation
3 MIN READ
0
The “great filter” is an epigenetic trap
4 MIN READ
0
Atomic-resolution of cell type signaling
4 MIN READ
0
Unraveling evolutionary pseudoscience
2 MIN READ
0
Eibi Nevo gets it wrong
3 MIN READ
0
Rs3827760 is Val370Ala and EDARV370A
3 MIN READ
0
From “Blood Music” to Evolution 2.0
5 MIN READ
0
Olfaction & the octopus and human genomes
3 MIN READ
0
Protosuns, prebiotic molecules, proteins, and people
4 MIN READ
0
Mammalian-wide interspersed repeats (MIRs)
2 MIN READ
0
Ecological speciation vs revised evolutionary syntheses
6 MIN READ
0
Ecology replaces the extended evolutionary synthesis
4 MIN READ
0
The stability of organized genomes (4)
3 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
The stability of organized genomes (2)
5 MIN READ
0
Epimutation.com: a domain of confusion
8 MIN READ
0
Light -induced nucleic acid-mediated gene duplication?
< 1 MIN READ
0
Is the best Chinese research from China?
3 MIN READ
0
The stability of organized genomes
5 MIN READ
0
Viruses, amino acids, and somatic cell types (3)
9 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
Big Bang Cosmology vs Reality
< 1 MIN READ
0
RNA-mediated terms of virus-induced en-deer-ment
2 MIN READ
0
Domestication via a single amino acid substitution
2 MIN READ
0
Hematopoiesis and practopoiesis
4 MIN READ
0
RNA-mediated morphological AND behavioral phenotypes
2 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Is photic-zone ribosomal diversity linked to all biodiversity?
2 MIN READ
0
Picornaviruses moving between primates (or not)
2 MIN READ
0
The pseudoscientific nonsense of behaviorists
< 1 MIN READ
0
Riding the wrong direction
3 MIN READ
0
Decreased phenotypic variation: Faith in Facts
7 MIN READ
1
Faithfully repaired DNA
5 MIN READ
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
MicroRNA – controlled ecological adaptations
5 MIN READ
0
Celebrating independence from ridiculous theories
3 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
The sum of our RNA-mediated parts
2 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
Unconscious affect (revisited)
2 MIN READ
0
Iron, ferritin, thyroxine
2 MIN READ
0
“Evolution” of sex differences?
2 MIN READ
0
Olfactory perception of genetic information
2 MIN READ
2
RNA-mediated cell type differentiation: Honeybee
< 1 MIN READ
0
Nutrient stress-induced RNA-mediated pathology
< 1 MIN READ
0
Amino acid substitutions are not mutations
2 MIN READ
0
RNA-mediated events from A to Z
2 MIN READ
0
What I cannot create I eliminate from discussion
3 MIN READ
0
RNA-mediated development (2)
< 1 MIN READ
0
RNA-mediated development
2 MIN READ
0
Creating and maintaining the human virome
2 MIN READ
0
Healthy mutants
2 MIN READ
0
Uniquely epigenomic gene regulation
2 MIN READ
0
MicroRNAs and inappropriate functions
2 MIN READ
0
Rejecting pseudoscientific nonsense
6 MIN READ
1
Living the life that randomness created? (Sarcasm alert)
3 MIN READ
0
30 years of theoretical nonsense
3 MIN READ
0
microRNAs, glycosylation, and genomes
4 MIN READ
0
Unknown mechanisms and conclusions
2 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Physicians who practice evolutionary medicine?
3 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Tweaking the story to fit the theory
5 MIN READ
0
Appetite for ingesting theories (raw)
< 1 MIN READ
0
I forgot. How do mutations cause evolution?
4 MIN READ
0
One amino acid substitution, genes, and brain activity
3 MIN READ
0
Batch effect vs epigenetic effects
3 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
Missing a fact: microRNAs are genomic biomarkers
4 MIN READ
1
Bee-birthed epigenetics and primate cell types
5 MIN READ
0
Scientists lose. A sci-fi author gains credibility
2 MIN READ
0
Vitamin B3 and DNA repair
4 MIN READ
0
Bees and primates automagically evolve
3 MIN READ
0
Ignoring systems complexity (it’s too complicated)
3 MIN READ
0
Five years of Ferguson
2 MIN READ
0
Computing via phosphorylation and fixation
3 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
The microbiome, pharmacogenetics, and privacy
< 1 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Protein isoforms do not evolve
3 MIN READ
0
Tissue type variation and expression of genes
< 1 MIN READ
0
From gut bacteria to breast milk and back
5 MIN READ
0
Chance mutations — not natural selection
5 MIN READ
0
Viruses in gut microbes
4 MIN READ
0
How to find a “holy grail” under your nose
3 MIN READ
0
Physics, chemistry, light, and life
2 MIN READ
0
Finding odor and taste receptors everywhere
6 MIN READ
0
Linking the origin of birds to dinosaurs
< 1 MIN READ
0
An epigenetic mark links algae, worms, and flies
2 MIN READ
0
Effect and affect of a single base-pair change
4 MIN READ
0
Tet3 regulation of nutrient-dependent cell type differentiation
4 MIN READ
0
Thermodynamics and protein folding landscapes
2 MIN READ
0
RNA-mediated silencing of a chromosome
3 MIN READ
0
Viruses, proteins, and gut metagenomes do not evolve
< 1 MIN READ
0
Pathology constrains X-linked evolution
2 MIN READ
0
Re-inventing a completely new thing
4 MIN READ
0
Feedback loops link insects to human brains
2 MIN READ
0
Viruses and cell type differentiation
3 MIN READ
0
RNA-mediated cell types and precision medicine
5 MIN READ
0
DNA Methylation and organized genomes (2)
10 MIN READ
0
DNA Methylation and organized genomes
7 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
Biology by itself
2 MIN READ
0
Amino acid-dependent cell type differentiation
8 MIN READ
0
Nutrient-dependent RNA interference (2)
4 MIN READ
0
Nutrient-dependent RNA interference
4 MIN READ
0
Mutisensory integration: watching the paradigm shift
12 MIN READ
0
Origin of life and cancer (1,2,3)
2 MIN READ
0
A genetic variant refutes neo-Darwinism
6 MIN READ
0
MicroRNAs and invasive phenotypes
< 1 MIN READ
0
Silencing genes and serious scientists
3 MIN READ
0
Nutrient-dependent microRNAs control cell types
6 MIN READ
0
MicroRNAs and memory
< 1 MIN READ
0
Deeply ingrained thoughts
< 1 MIN READ
0
Graphic misrepresentations of ecological adaptation
2 MIN READ
0
Too many targets for theories
3 MIN READ
0
Methylation maintains cell type differences (2)
2 MIN READ
0
Methylation maintains cell type differences
3 MIN READ
0
Creating nothing but a theory (3)
4 MIN READ
3
Creating nothing but a theory (2)
4 MIN READ
0
Creating nothing but a theory
4 MIN READ
0
Viruses and ecologically adapted animals
2 MIN READ
0
2 genes in 2 species (too expensive and too insignificant)
11 MIN READ
0
The quantum / classical RNA-mediated ‘tipping point’
3 MIN READ
0
Epigenetic effects of soil bacteria on plants
< 1 MIN READ
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Anti-entropic solar energy
5 MIN READ
0
Mimicking claims and ignoring facts
4 MIN READ
0
Correctly modeling life on this planet
3 MIN READ
0
Correctly modeling ecological adaptation
4 MIN READ
0
Behavior (4): All responses are RNA-mediated in birds
4 MIN READ
0
Questions about life’s diversity
21 MIN READ
0
UV-light mutations and gene loss (not gain)
5 MIN READ
0
Virus-driven origin of life
2 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
Walk towards the light
< 1 MIN READ
0
Two types of microRNA are not double agents
2 MIN READ
0
Epigenetics Skeptism
5 MIN READ
0
Assembling yourself: Molecular self / other recognition
4 MIN READ
0
What about birds?
5 MIN READ
0
Virus-driven cell type differentiation
2 MIN READ
0
RNA directed DNA methylation and cell types
4 MIN READ
0
Implicating microRNAs in cancer
2 MIN READ
0
Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs
2 MIN READ
0
Reverse phosphorylation
7 MIN READ
0
RNA-mediated repurposing in microbes and adaptations in primate brains
2 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
From 3-D to epigenetically-effected 4-D genome make-up
5 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
An epigenetic trap (the prequel)
5 MIN READ
0
Imagining that data historically supports evolutionary theory
7 MIN READ
0
Atheism: Arrogant, useless, and divisive ignorance
7 MIN READ
0
The anti-entropic force of "Nature"
2 MIN READ
0
Nutritional epigenetics, exercise, and immune system integrity
4 MIN READ
0
What if Darwin was not still dead?
2 MIN READ
0
Military combat training to fight disease (2)
3 MIN READ
0
Military combat training to fight disease
3 MIN READ
0
Theoretical physics and molecular biology
5 MIN READ
0
Atoms to ecosystems is not almost a molecular ecology
3 MIN READ
0
Epigenetic effects of viruses on cellular homeostasis (2)
2 MIN READ
0
RNA-mediated epigenetic modification via DNA-methylation
4 MIN READ
0
Quantum physics, quantum biology, and quantum consciousness
4 MIN READ
0
How fast can evolutionary theory be changed?
5 MIN READ
0
Biological energy and a microbiome model of a light-driven time machine
3 MIN READ
0
The biologically-based origin of the mammalian placenta (2)
6 MIN READ
0
Quantum Superpositions: let there be light
4 MIN READ
0
Are viruses microRNAs? (2)
5 MIN READ
0
Are viruses microRNAs?
3 MIN READ
0
Sneaking up from behind (2)
3 MIN READ
0
Sneaking up from behind
4 MIN READ
0
Quantum entanglement, mass, and biomass
4 MIN READ
0
Physicists: Desperate Acts
16 MIN READ
0
An epigenetic trap (the sequel)
10 MIN READ
0
Mute points: most are afraid to mention them
6 MIN READ
0
All of “like kind” (Part 2)
2 MIN READ
0
All of "like kind" in the (bigger) family
6 MIN READ
1
Environment epigenetically shapes the immune system
3 MIN READ
0
Beneficial microbes kill beneficial mutations
4 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
A single amino acid substitution differentiates cell types of E. coli
3 MIN READ
0
Unconstrained evolutionary innovability
4 MIN READ
0
RNA-protein interactions reveal biophysical to ecological landscapes
2 MIN READ
0
Mutagenesis: Replacing facts with theories
5 MIN READ
0
ISHE's human ethology group
2 MIN READ
0
Amino acid homeostasis for a Happy New Year!
6 MIN READ
0
Understanding cell type differentiation
3 MIN READ
0
From Hydra to humans vs a Lakatosian research program
4 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
Removing natural selection; reshaping the horse; adjusting evolutionary theory
4 MIN READ
0
Communication, not mutations
2 MIN READ
0
Models by evolutionary biologists are not models
2 MIN READ
0
The future of physics predicts no future for evolutionary theory
3 MIN READ
0
Model organisms: the birds and the bees
3 MIN READ
0
Chemical ecology and RNA-mediated control of DNA loops
< 1 MIN READ
0
Atoms to ecosystems: Evolutionary theory vs the coelacanth
6 MIN READ
0
Jumping back: Science or Pseudoscience? (2)
2 MIN READ
0
Jumping back: Science or Pseudoscience?
6 MIN READ
0
Single-cell level assay of protein biosynthesis and degradation
2 MIN READ
0
Glycine and GnRH: Am I being pedantic?
4 MIN READ
0
Extensive molecular evidence vs ridiculous theories
2 MIN READ
0
Dual genomes: exposing the evolution industry
5 MIN READ
0
One test of bioenergetic health?
2 MIN READ
0
Meaningful dialogue, anonymous fools and idiot minions
4 MIN READ
0
Epigenetic pharmacology and RNA-mediated transciptional landscapes
3 MIN READ
0
RNA-mediated events and "The Theory of Everything"
4 MIN READ
0
Sackler Colloquium: Effects or AFFECTS on Behavior
2 MIN READ
0
Thermodynamic constraints and ecological adaptations sans evolution
6 MIN READ
0
Eliminating correlations from evolutionary ecology
6 MIN READ
0
RNA-mediated species specificity
2 MIN READ
0
Are mutations beneficial?
4 MIN READ
0
The key to science: experimental evidence
5 MIN READ
0
Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
0
There’s a model for that!
5 MIN READ
0
Biologists puzzled by evolved RNAs and decaying DNA
6 MIN READ
0
SNPs and millions of small variations in the human genome
3 MIN READ
0
More than a bag of chemicals?
2 MIN READ
0
Achiral GnRH: no prophesy, just prediction
9 MIN READ
0
Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
0
Making sense of quotes scattered across disciplines
2 MIN READ
0
Intelligent viruses and cancers?
10 MIN READ
0
Complex behaviors of cell types in cancer
6 MIN READ
0
De novo DNA methylation?
3 MIN READ
0
RNA eclipses the importance of DNA to cell type differentiation
4 MIN READ
0
We need pattern recognition, not proclamations
3 MIN READ
0
We need pattern recognition, not a prologue
6 MIN READ
0
Pharmacogenomics
3 MIN READ
0
Sexual differentiation of cell types in plants
2 MIN READ
0
A model of MHC 'evolution'
2 MIN READ
0
From deep time into real time: What evolutionary processes?
10 MIN READ
0
In theory, or supported by experimental evidence?
5 MIN READ
0
It’s cell type differention, not cell fate determination (2)
3 MIN READ
0
Are evolutionary theorists 'nob ends'?
5 MIN READ
2
ALPHA GENOMIX
7 MIN READ
2
No excuses: Creation and the meaning of organismal complexity
7 MIN READ
0
Nutrient-dependent gene duplication in plants (but not animals?)
4 MIN READ
0
Evolutionary theorists justify fear of the Ebola viruses
2 MIN READ
0
Evolutionary theorists and evolutionary theists live under rocks
< 1 MIN READ
0
No understanding of biodiversity
2 MIN READ
0
Understanding physical forces of ecological variation and adaptation
< 1 MIN READ
0
Eliminating evolutionary theory
3 MIN READ
0
Behavioral ecology: please continue to believe in our fantasies
3 MIN READ
0
2014 and 2004 Nobel Prize in Medicine
3 MIN READ
0
RNA-mediated events: chromosomal rearrangements and genomic rearrangements
2 MIN READ
2
How much good can be attributed to social science theories?
< 1 MIN READ
0
RNA-mediated genetic engineering (Part 3)
< 1 MIN READ
0
RNA-mediated genetic engineering (Part 2)
3 MIN READ
0
RNA-mediated genetic engineering
2 MIN READ
0
RNA-mediated events are not a matter of faith
2 MIN READ
0
Color vision refutes the evolutionary dogma of gene duplication
4 MIN READ
0
Unassailable evidence vs assumptions
4 MIN READ
0
Forces of "Nature" limit dissemination of information
4 MIN READ
0
Genomic surveillance ends our world of RNA-mediated ecological adaptations
2 MIN READ
0
Systems biology and memory disorders
3 MIN READ
0
RNA-mediated cell type differentiation and behavior
3 MIN READ
0
Different physical locations and different molecular mechanisms of health and disease
2 MIN READ
0
Metabolism, fixation, health or neurodegerative disorder
2 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Physics denied; pseudoscientific nonsense accepted
2 MIN READ
0
Ecological variation and niche construction: 1, 2, 3
6 MIN READ
0
Epigenetically-effected metabolic shifts and ecological adaptations
3 MIN READ
0
Evolving DNA before RNA
4 MIN READ
0
Stop evolutionary theorists. Kill cancers
3 MIN READ
0
Did our adapted mind evolve? (Revisited)
2 MIN READ
0
De novo gene Creation sans evolution of genes via mutations
4 MIN READ
0
Did our adapted mind evolve?
6 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Miracles are not miracles to evolutionary theorists
2 MIN READ
0
Mathematical model: microRNA and epigenetic regulation
2 MIN READ
0
Seemingly futile cycles are not thermodynamically futile
3 MIN READ
0
Do bacterial proteins evolve?
3 MIN READ
0
“Kardashians” in science
< 1 MIN READ
0
Probable changes in connectivity
2 MIN READ
0
New technique used in report of atomic-level ecological adaptations
3 MIN READ
0
Can epigenetic inheritance occur without concurrent changes in morphology AND behavior?
3 MIN READ
0
Memory of repression and memory of behavior (2)
< 1 MIN READ
0
Memory of repression and memory of behavior
2 MIN READ
0
Quantum physics meets Evolutionary Psychology News
2 MIN READ
0
Nutrient-dependent pheromone-controlled exercise-induced physiques
< 1 MIN READ
0
Watching and waiting for more retractions
2 MIN READ
0
RNA-mediated ecological adaptations of teeth
4 MIN READ
0
A molecular visualizer of worthwhile molecular biology
2 MIN READ
0
RNA-mediated species diversification from microbes to primates
3 MIN READ
0
RNA-mediated events found everywhere
2 MIN READ
0
Reseachers think copy number variation is genetically determined
< 1 MIN READ
0
Some neuroscientists think a mutation led to human language development
< 1 MIN READ
0
Genotype, observed phenotype, and distinctly disordered behaviors
3 MIN READ
0
Is the problem an internet echo or Feierman's ethics?
2 MIN READ
0
Behavior (3): All responses are RNA-mediated in bees
3 MIN READ
0
RNA-mediated ecological adaptation is not evolution
2 MIN READ
0
Exploding genomes and chromosomal rearrangements via RNA-mediated events
2 MIN READ
0
Behavior (2): All responses are RNA-mediated not genetically-determined
4 MIN READ
0
Behavior: The first response is RNA-mediated not genetically-determined
3 MIN READ
0
Mechanisms that are not understood increase clarity
4 MIN READ
2
Pattern recognition and conserved receptors (TAARs)
5 MIN READ
0
Nutrient-dependent erythropoiesis and anemia
6 MIN READ
0
Evolutionary heritage or ecological adaptation? Racism versus reality
4 MIN READ
0
A relatively young branch of science called epigenetics
4 MIN READ
0
Insect homology and diversity attributed to mutations
2 MIN READ
0
Baby talk: More misrepresentations of ecological adaptations
2 MIN READ
0
Comparing divergent model organisms
2 MIN READ
1
A microRNA-mediated mechanism that is epigenetically inherited
2 MIN READ
0
Epimutations: Attacking pseudoscientific dogmas
4 MIN READ
0
Order and disorder: Ecological adaptations not mutations
6 MIN READ
0
microRNAs and species relationships
3 MIN READ
0
Drunks and Monkeys: Pseudoscientific nonsense
2 MIN READ
0
The quantum biology of consciousness
3 MIN READ
0
Behavior is receptor-mediated
10 MIN READ
0
Genes and Race: Human History?
2 MIN READ
0
Soft atheism: a case for Creation
< 1 MIN READ
0
Nutrition, pheromones and cancer (2)
2 MIN READ
0
Ecologically linked adapted ants and brains
2 MIN READ
0
MiRNAs methylation and ecological adaptation sans mutations
2 MIN READ
0
Not focused and self-aggrandizing
2 MIN READ
0
Nutrient-dependent cooperation vs cannibalism (video)
2 MIN READ
0
Another powerful refutation of mutation-initiated natural selection
4 MIN READ
0
The new light of chromosomal rearrangements
3 MIN READ
0
Darwinian theories vs Darwin's facts
2 MIN READ
0
Chromosomal rearrangements and ecological adaptations
4 MIN READ
0
The wrong picture of our evolution
4 MIN READ
0
96 fixed amino acid substitutions, not 96 genes
6 MIN READ
0
Jay R. Feierman
3 MIN READ
0
Don't tell the Creationists
2 MIN READ
0
Targeting a cancer gene
2 MIN READ
0
Alternative splicings (very technical)
2 MIN READ
0
Pulses of olfactory/pheromonal input
2 MIN READ
0
Social experiences epigenetically effect gene networks
2 MIN READ
0
Pheromone-controlled thermodynamics and cancer
2 MIN READ
0
Seeds of life: astrobiological theory and mutations theory
3 MIN READ
0
Your comment is awaiting moderation
2 MIN READ
0
Nutrient-dependent pheromone-controlled stickleback evolution
2 MIN READ
0
Functional coding variants are not mutations
2 MIN READ
0
Mirror neurons and microRNA: theory vs biological facts
4 MIN READ
0
Understanding the role of mutations and evolution
4 MIN READ
0
Evolution: innovations may have non-adaptive origins (sans mutations)
2 MIN READ
0
Are pheromones responsible for human body odour assessment?
2 MIN READ
0
Hormones effect sensitivity to androsterone
2 MIN READ
0
Epigenetic effects underlie sexual preferences IV
< 1 MIN READ
0
Music to our ears and song in birds: a common sense approach
2 MIN READ
0
A newly discovered hypothalamic neurogenic niche in the brain
< 1 MIN READ
0
Random mutations theory and pervasive mosaic evolution (the brain)
2 MIN READ
0
The challenges of a Darwinian approach to anything
3 MIN READ
0
Fatal attractions: a fear of pheromones
2 MIN READ
0
Sex differences in Alzheimer's and everything else
2 MIN READ
0
The Knowing Nose: Chemical Signals Communicate Human Emotions
< 1 MIN READ
0
Human Pheromones: Epigenetic Effects of Odors and Their Affects on Behavior
2 MIN READ
0
How Species Diversify
2 MIN READ
0
The same neural mechanisms are at work in worms and humans
2 MIN READ
0
Pheromonemotionally speaking
2 MIN READ
0
Playing with breasts (e.g, with a new THEORY of why only heterosexual men love them)
3 MIN READ
0
Epigenetic effects of docosahexaenoic acid (DHA) on the primate brain
2 MIN READ
0
Embracing galaxy-wide, cellular, and brain complexity
2 MIN READ
0
Bio-CHEMICAL complexity
< 1 MIN READ
0
Pheromones and multicellularity
< 1 MIN READ
0
Epigenetic effects on the evolution of behavior
2 MIN READ
0
CB Nemeroff: Off Restriction
< 1 MIN READ
0
Chemical signaling may shed light on how the brain reacts to its environment
2 MIN READ
0
Species specificity in gene expression in the brain
2 MIN READ
0
Children’s healthy diets lead to healthier IQ
< 1 MIN READ
0
Human Pheromones: Diversity of signaling pathways and a common response (Part 2)
2 MIN READ
0
Human pheromones are like sugar (and spice)
< 1 MIN READ
0
Bee research, human sweet perception, human pheromones, and metabolic disorders
< 1 MIN READ
0
Human pheromones and inner conflict about evolution (1102 words)
4 MIN READ
0
A thought experiment
3 MIN READ
0
Brain Activation Areas of Sexual Arousal with Olfactory Stimulation in Men
2 MIN READ
0
Human pheromones: Olfaction, odor receptors, learning, memory, mood, brains and behavior
< 1 MIN READ
0
Human pheromone- and nutrient-dependent brain development and behavior
2 MIN READ
0
Human pheromones and the visual appeal of other people (Part Three)
2 MIN READ
0
Human pheromones and the visual appeal of other people (Part Two)
2 MIN READ
0
Human pheromones and brain development
2 MIN READ
0
More than speculation: adaptive evolution in species from microbes to man
2 MIN READ
0
Human pheromones and your immune system
< 1 MIN READ
0
A fallacious leap? Ancestral and derived traits
3 MIN READ
0
Modeling odor processing in microbes, mice, and mankind
2 MIN READ
0
Human Pheromones in Socioaffective Neuroscience & Psychology
2 MIN READ
0
Pheromones and the “Bruce effect” in wild or domesticated horses and primates
2 MIN READ
0
They are what they eat, and so are we
2 MIN READ
0
How memory works
2 MIN READ
0
A Preoccupation With Modesty…
2 MIN READ
0
Pheromones: from microbes to man
< 1 MIN READ
0
The biology of behavior: Seeing more clearly
< 1 MIN READ
0
Effects of pheromones on menstrual synchrony and a gay man
2 MIN READ
0
Did viruses make mammals communicate with pheromones?
2 MIN READ
0
Do Pheromones Play a Role in Our Sex Lives: Scientific American
< 1 MIN READ
0
Human Pheromones: 2010 Powerpoint slides and 2011 poster presentation
2 MIN READ
0
Epigentics and the baby connectome
2 MIN READ
0
Cookbook chemistry: food odors and hormones
< 1 MIN READ
0
Epigenetics and the connectome
2 MIN READ
0
Human pheromones and food odors
< 1 MIN READ
0
Pheromones and the Evolution of Drug Resistance
< 1 MIN READ
0
Docosahexaenoic acid and autism: praying for hope, or preying on hope
< 1 MIN READ
0
Timing is key in the proper wiring of the brain: study
2 MIN READ
0
Human pheromones provide clues to personality
< 1 MIN READ
0
Human Pheromones may influence brain chemistry into adulthood
< 1 MIN READ
0
Human Pheromones and sex differences in brain maturation
< 1 MIN READ
0
Progress in brain research (e.g., starting over)
< 1 MIN READ
0
How pheromones work (in 57 words or more)
< 1 MIN READ
0
Pheromone-enhanced behavior in sexually inexperienced females
2 MIN READ
0
Avian ‘Axe effect’ attracts attention of females and males
2 MIN READ
0
The Mind’s Eyes: Mindful modeling of brain directed behavior
2 MIN READ
0
Human pheromones: social odors and food odors
< 1 MIN READ
0
Honeybees, food odors, and perfume
< 1 MIN READ
0
Avian recognition of human faces
< 1 MIN READ
0
Human Pheromones Affect Women's Behavior
2 MIN READ
0
A lesser role for olfaction and pheromones in humans?
1 MIN READ
0
Creating a Myth
< 1 MIN READ
0
Pheromones in birds, other mammals, and us
< 1 MIN READ
0
The great pheromone myth revisited (including biological factors in the development of sexuality)
4 MIN READ
0
The great pheromone myth revisited (including biological factors in the development of sexuality)
4 MIN READ
0
Social selection: genetic contribution of viruses to life on earth
< 1 MIN READ
0
Dogs and humans: Then and now
< 1 MIN READ
0
Wikipedia comments by James V. Kohl
5 MIN READ
0
Excellent new book about pheromones
< 1 MIN READ
0
Study design| Psychophysics experiment | Perspective on conditioning
< 1 MIN READ
0
Adrenarche and odor preferences
2 MIN READ
0
For ethologists: Observation does not trump molecular biology
2 MIN READ
0
Human Pheromones and The Philosophy of Science
2 MIN READ
0
Genes, Hormones, and Behavior (for other scientists)
4 MIN READ
0
Love at first sight: Selective breeding, pheromones, and Divine intervention
3 MIN READ
0
A fundamental attribution error: Love at first sight
3 MIN READ
0
Human Pheromones
< 1 MIN READ
0
Pheromones and olfaction in the birds and the bees: from yeasts to you
2 MIN READ
0
Debunking the myth of pheromones
< 1 MIN READ
0
Tears and fears of pheromones
2 MIN READ
0
Exotic Pheromones and Concentrates
2 MIN READ
0
Marketing vs. the truth about human pheromones
2 MIN READ
0
Epigenetics, science fiction, and scientific fact
2 MIN READ
0
Results: increased flirtatious behavior and self-reported attraction
2 MIN READ
0
Pheromones and sexual behavior in birds
< 1 MIN READ
0
Is it what he or she sees in you, or is it your pheromones?
2 MIN READ
0
Product comparisons and human pheromone sciences
3 MIN READ
0
Conditioning of the human pair bond by human pheromones
< 1 MIN READ
0
Conditioned sexual arousal to odor
2 MIN READ
0
Scent signals
< 1 MIN READ
0
Pheromones and signature mixtures
2 MIN READ
0
Comparative biology of pheromonal communication
< 1 MIN READ
1
Food preferences and mate preferences
< 1 MIN READ
0
Presentation on Human Pheromones delivered on August 3, 2010
2 MIN READ
0
Sold on the human VNO?
< 1 MIN READ
0
Effects of pheromones attributed to touch (in mice)
< 1 MIN READ
0
How pheromones work by James V. Kohl
2 MIN READ
0
Pheromones of pregnant women effect prolactin in men
< 1 MIN READ
0
Another book author's comment on "The Great Pheromone Myth"
< 1 MIN READ
0
An attempt to change the concept
< 1 MIN READ
0
Luteinizing hormone, sex, and smell (18 years later)
2 MIN READ
0
[…] See also: A lighting requirement for life. […]
Tight DNA packaging protects against ‘jumping genes,’ potential cellular destruction
https://www.sciencedaily.com/releases/2016/09/160901125055.htm
Thanks to Teresa Binstock for bringing this article about supercoiled DNA to my attention. “Tight DNA packaging” and “tightly coiled DNA” are terms used to obfuscate the facts about supercoiled DNA that have already linked viral latency to all pathology.
Supercoiled DNA protects the organized genomes of all living genera from virus-driven entropy. That fact has been the focus of my efforts here and at RNA-mediated.com
Why is Teresa Binstock — co-author of our 1996 Hormones and Behavior review — the only one who seems to be following the literature on RNA-mediated cell type differentiation?
All serious scientists already know that heterochromatin function is nutrient energy-dependent and transgenerationally inherited via epigenetic effects of sensory input that alters the microRNA/messenger balance. Epigenetically altered morphological and behavioral phenotypes are linked from the innate immune system to heterochromatin function because it top-down causation did not link the immune system from metabolic networks to genetic networks in all organisms, the biodiversity of life on Earth would not exist.
Direct interrogation of the role of H3K9 in metazoan heterochromatin function
https://genesdev.cshlp.org/content/early/2016/08/26/gad.286278.116
Abstract: A defining feature of heterochromatin is methylation of Lys9 of histone H3 (H3K9me), a binding site for heterochromatin protein 1 (HP1). Although H3K9 methyltransferases and HP1 are necessary for proper heterochromatin structure, the specific contribution of H3K9 to heterochromatin function and animal development is unknown. Using our recently developed platform to engineer histone genes in Drosophila, we generated H3K9R mutant flies, separating the functions of H3K9 and nonhistone substrates of H3K9 methyltransferases. Nucleosome occupancy and HP1a binding at pericentromeric heterochromatin are markedly decreased in H3K9R mutants. Despite these changes in chromosome architecture, a small percentage of H3K9R mutants complete development. Consistent with this result, expression of most protein-coding genes, including those within heterochromatin, is similar between H3K9R and controls. In contrast, H3K9R mutants exhibit increased open chromatin and transcription from piRNA clusters and transposons, resulting in transposon mobilization. Hence, transposon silencing is a major developmental function of H3K9.
VARIATION IN “JUNK” DNA LEADS TO TROUBLE
https://today.duke.edu/2016/08/variation-%E2%80%9Cjunk%E2%80%9D-dna-leads-trouble
Between you and your neighbor, there’s only about 0.1 percent difference between your two sets of DNA. Even more, scientists think that this small difference affects the way many parts of the human body are designed: eye color, hip shape, and your chance of becoming sick.
“Variation is not only important for how genes and proteins function, but it can also occur in the noncoding, repetitive portions of the genome. “What we found in this study is probably the tip of the iceberg. There could be all sorts of functional consequences to having variation within the complex, repetitive portion of the genome that we don’t know about yet.”