Iron, ferritin, thyroxine

By: James V. Kohl | Published on: June 26, 2015

The picture includes vegetation and rock formations. It is from Capital Reef in Utah. No serious scientist has ever suggested a link from the formations to biologically-based cause and effect outside the context of what is known about RNA-mediated events that link iron metabolism to hormones and the physiology of nutrient-dependent reproduction in all genera via amino acid substitutions.

Biologically recycled continental iron is a major component in banded iron formations
Excerpt:

These results show that Fe sources and pathways for BIFs reflect the interplay between abiologic (hydrothermal) and biologic processes, where the latter reflects DIR that operated on a basin-wide scale in the Archean.

Reported as:

Iron: A biological element?

Excerpt: 
The idea that an organism could metabolize iron may seem strange today, but Earth was very different 2.5 billion years ago. With little oxygen in the atmosphere, many organisms derived energy by metabolizing iron instead of oxygen.

My comment: Does anyone who is not a evolutionary theorist not know of the link from iron to biologically-based cause and effect in species from microbes to man? Has any serious scientist provided evidence that links biologically-based cause and effect to metabolism across 2.5 billion years?
See instead: Oxidation of cellular amino acid pools leads to cytotoxic mistranslation of the genetic code
Excerpt:

Reactive oxygen species (ROS) generated under oxidative stress via the Fenton reaction are capable of catalyzing the conversion of Phe to m-Tyr, which could potentially threaten the fidelity of protein synthesis in the absence of editing (Maskos et al., 1992; Stadtman and Levine, 2003).

Is anyone too biologically uninformed to realize that the conserved molecular mechanisms of biophysically constrained nutrient-dependent protein folding link iron metabolism from our gut microbes to survival of our species and to the survival of other species via RNA-mediated metabolic networks and genetic networks?
One need only start with the light-induced de novo creation of amino acids to link RNA-mediated amino acid substitutions from ecological variation to ecological adaptations in all genera via their physiology of reproduction. If you start with mutations and evolution, you can’t make sense of the obvious link from iron to ferritin and thyroxine via metabolic networks and genetic networks in species from microbes to humans.
The Molecular Biology of Human Iron Metabolism
Conclusion

…iron homeostasis is important to understand the range of disorders that involve iron deficiency or iron excess. Factors that reduce hepcidin, including essentially any form of chronic liver disease, can lead to the hyperabsorption of iron and to iron overload.41–43 Conversely, excess hepcidin, as in states of chronic disease or chronic inflammation, impairs iron recycling, causing iron-restricted anemia.

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