Somatic hypermutation vs RNA-mediated events

By: James V. Kohl | Published on: September 5, 2015

Change in environment can lead to rapid evolution, researchers say

135 genes evolved in response to the new environment. Most of the changes in the gene expression were internal and dealt with a fish’s biological processes such as metabolism, immune function and development.

My comments:

1) Journal article excerpt: “… few studies have been able to capture the initial patterns of plasticity and subsequent adaptive divergence of traits in natural populations.”
All experimental evidence links physics and chemistry via molecular epigenetics. Viral microRNAs link entropic elasticity to genomic entropy. Nutrient-dependent microRNAs link RNA-mediated DNA repair to healthy longevity via RNA-mediated amino acid substitutions that stabilize organized genomes.

Nutrient-dependent/pheromone-controlled adaptive evolution: a model

Excerpt: “Animal models are often used to model human physical and mental disorders. The honeybee already serves as a model organism for studying human immunity, disease resistance, allergic reaction, circadian rhythms, antibiotic resistance, the development of the brain and behavior, mental health, longevity, diseases of the X chromosome, learning and memory, as well as conditioned responses to sensory stimuli (Kohl, 2012).”
2) Can anything that pseudoscientists claim occurs in the context of evolution occur outside the context of what is known to serious scientists about G protein-coupled receptors?

Study reveals the genetic start-up of a human embryo

Comment by Andrew Jones (aka anonymous_9001)

Kohl doesn’t understand what happens during differentiation and confuses differentiation of cells during maturation of a single organism over its lifetime with changes occurring over multiple generations.
Duplications do not occur in somatic cells during maturation and neither do amino acid substitutions. All of your cells have the exact same genome besides RBCs and immune system cells that undergo somatic hypermutation.

Andrew Jones (aka anonymous_9001) also wrote: Criticisms of the nutrient-dependent pheromone-controlled evolutionary model 
He may be the most ignorant of all people who have ever graduated college with a degree in biology.
See for contrast: Amino Acid Difference Formula to Help Explain Protein Evolution

The conclusions stated above are subject to the limitations of statistical inference, but correlations of this magnitude with all 190 amino acid pairs cannot be due to chance.

Nothing in Biology Makes Any Sense Except in the Light of Evolution

“…the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla. ( p. 127)”

Andrew Jones and others like him may continue their attempts to tell others about how evolution does not occur.
I reiterate:

Andrew Jones claims that:
Duplications do not occur in somatic cells during maturation and neither do amino acid substitutions.

RNA-mediated gene duplication: the rat preproinsulin I gene is a functional retroposon
RNA-mediated epigenetic regulation of DNA copy number
RNA-mediated gene activation
RNA-mediated epigenetic regulation of gene expression
rna mediated and anything published to this blog site.
Ask yourself whether you think that Change in environment can lead to rapid evolution via somatic hypermutations, or if ecological variation is linked to ecological adaptation via RNA-mediated events that link the nutrient-dependent physiology of reproduction to cell type differentiation in all cells of all individuals of all living genera.

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