Energy-dependent biodiversity (4)
(click to enlarge)
Excerpt:
In an attempt to do damage control, one of the organizers of the Royal Society paradigm shift meeting (not Denis Noble) sent me an email, which follows, asking that I stop referring to the Royal Society meeting as such. Why? Because he speaks for scientists who think they can control the scientific discourse as it was controlled at the time of Darwin.
My comment: Re: The need for discussion of viruses (e.g., phages)
Quorum Sensing Determines the Choice of Antiphage Defense Strategy in Vibrio anguillarum
The application of the defense strategy appears here (2002):
Higher Abundance of Bacteria than of Viruses in Deep Mediterranean Sediments
The strategy links the innate immune system to energy-dependent healthy longevity or from virus-driven energy theft to all pathology.
See also: Counting viruses and bacteria in photosynthetic microbial mats.
The ratio has been linked from the sun’s quantized anti-entropic virucidal energy to RNA-mediated DNA repair via hydrogen-atom transfer in DNA base pairs in solution. The energy transfer links the innate immune system and microRNA flanking sequences from angstroms to ecosytems in the context of the physiology of reproduction and supercoiled DNA.
The facts are neo-Darwinian theory killers that have been ignored for more than 20 years. Whose lives did they think they were toying with — besides their own? The Precision Medicine Initative and National Microbiome Initiative have already linked the metabolic networks and genetic networks of all living genera with facts about RNA-mediated protein folding chemistry. It’s biophysically constrained! Surprise! Contraint-breaking mutations cannot be linked to Mutation-Driven Evolution outside the context of mathematical models, definitions and ridiculous assumptions (reported by you with exquisite consistency and clarity).
So now, they plan a meeting; try to quell discussion of virus-driven energy theft and disease and then want to discuss damage control with you.
Get ’em, Suzan!
See also: Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape
Reported as:
Missense mutations (that change one amino acid for another) in histone H3 can produce a so-called oncohistone and are found in a number of pediatric cancers. For example, the lysine-36–to-methionine (K36M) mutation is seen in almost all chondroblastomas. Lu et al. show that K36M mutant histones are oncogenic, and they inhibit the normal methylation of this same residue in wild-type H3 histones. The mutant histones also interfere with the normal development of bone-related cells and the deposition of inhibitory chromatin marks.
My comment: I cannot keep up with the amount of pseudoscientific nonsense that is being touted in the last few attempt to save the careers of those who have placed all virus-driven energy theft into the context of mutations and/or natural selection and evolution.
Today, I found this domain: Oncohistone.com I suspect it was established to compete with information dissemination at RNA-mediated.com
But why? They are not linking energy-dependent changes in angstroms to ecosystems via RNA-mediated amino acid substitutions. They are not linking virus-driven energy theft to all pathology. They are linking a definition of missense mutations (that change one amino acid for another) to what they expect others to call oncohistones. That will help them continue to link mutations to pathology without linking virus-driven energy theft to the mutations.
I can’t remember if I already posted about that to this blog. But I wanted to ensure I placed it into the context of the domain they established and Suzan Mazur’s update on the Royal Society meeting.
The desperation is showing in every area of research where scientists have clung to definitions and assumptions for far too long.
See for comparison: MicroRNA-based regulation of epithelial–hybrid–mesenchymal fate determination
Energy-dependent changes in hydrogen-atom transfer in DNA base pairs in solution link microRNA-based regulation of all cell type fate determination to healthy longevity or from virus-driven energy theft to pathology.
In Energy-dependent biodiversity (2) I mentioned this:
All the confusion about linking the mouse model to humans via energy-dependent hydrogen-atom transfer in DNA base pairs, which are linked to supercoiled DNA and protection of organized genomes from virus-driven energy theft and genomic entropy is missing.
My comment: The confusion must be viewed in the context of this article: Structure of the T4 baseplate and its function in triggering sheath contraction
Reported as: How viruses infect bacteria: A tale of a tail
The scientists were also able to identify a minimal set of molecular components in the baseplate that work together like miniature gears to control the activity of the virus’s tail. These components, and the underlying functional mechanism, are the same across many viruses and even bacteria that use similar tail-like structures to inject toxins into neighboring cells.
“These findings are important for our understanding of how these contractile tail-like systems work,” says Leiman. “But they also set a benchmark for the complexity of biological systems that can be described at the atomic level.” The human body contains almost as many bacteria as human cells (30-40 trillion), and the human gut microbiota will likely represent an important target for personalized medicine in the future. “It is clear that we need to understand the detailed mechanisms by which these bacteria interact with each other and how phages are involved in these interactions.”
See also: Evolutionary ‘probables’ a positive step
Excerpt:
The new method samples evolutionary histories, called phylogenetic networks, and makes suggested connections between closely related species, or even multiple individuals within species.
“That’s one of the nice things about the Bayesian approach and why we went in that direction,” he said. “We don’t give biologists a single answer. We don’t say, ‘Here’s your optimal evolutionary history.’ We say, ‘Here’s a sample of evolutionary histories the method found while walking the space of possible evolutionary histories.'”
My comment: They don’t say anything about the fact that the history of any species is nutrient energy-dependent and controlled by the physiology of reproduction. If you asked them, they might claim that Mother Nature caused everything to happen automagically.
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3 MIN READ
0
RNAi: From magic bullet to billion dollar baby
4 MIN READ
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
Pseudoscientists ignore what serious scientists prove
6 MIN READ
0
GC-rich neo-Darwinian train wreck
5 MIN READ
0
Biophysically constrained cell type differentiation
3 MIN READ
0
From angstroms to ecosystems
7 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
Virus-driven downsizing of the human brain (3)
4 MIN READ
0
Do weak bosons evolve into leptons?
4 MIN READ
0
Q and A: Energy-dependent cell type differentiation
10 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
The end of neo-Darwinism
5 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity
4 MIN READ
0
Did “Nature” kill Steve Jobs? (3)
10 MIN READ
0
Funding the Human Genome Project-Write
2 MIN READ
0
RNA-mediated programming of E.coli
< 1 MIN READ
0
Did “Nature” kill Steve Jobs?
3 MIN READ
0
Virus-driven downsizing of the human brain (2)
< 1 MIN READ
0
RNA methylation (revisited)
< 1 MIN READ
0
Placing boundaries where none exist
< 1 MIN READ
0
Virus-driven downsizing of the human brain
2 MIN READ
0
MicroRNAs and sexual orientation
8 MIN READ
0
RNA methylation, learning, memory and behavior,
< 1 MIN READ
0
Innate immunity and multiplexing
7 MIN READ
0
RNA methylation (2)
7 MIN READ
0
Amino acids and virus penetration
3 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
Masters of deception about nature (2)
7 MIN READ
0
Masters of deception about nature
8 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
Cracking the Olfactory Code?
5 MIN READ
0
RNA methylation, behavior, and disease
6 MIN READ
0
Modelling life scientifically: RNA-mediated events
12 MIN READ
0
Energy-dependent RNA methylation (9)
2 MIN READ
0
Energy-dependent RNA methylation (10)
4 MIN READ
0
Energy-dependent RNA methylation (8)
4 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (6)
9 MIN READ
0
Energy-dependent RNA methylation (5)
3 MIN READ
0
Energy-dependent RNA methylation (4)
5 MIN READ
0
Energy-dependent RNA methylation (3)
10 MIN READ
0
Energy-dependent RNA methylation (1)
6 MIN READ
0
Secular humanism and ecoterrorism
4 MIN READ
0
Thermotolerance and longevity (2)
3 MIN READ
0
War Games: False Flag Terrorism (2)
4 MIN READ
0
War Games: False Flag Terrorism
5 MIN READ
0
Virus-driven energy theft: definition?
5 MIN READ
0
The tipping point? 50,000 publications (4)
3 MIN READ
0
Energy-dependent biodiversity (3)
7 MIN READ
0
Energy-dependent biodiversity (2)
2 MIN READ
0
Energy-dependent biodiversity
5 MIN READ
0
The tipping point? 50,000 publications (3)
6 MIN READ
0
Neo-Darwinism failed in 1995
3 MIN READ
0
Countdown to Genetics and Genomics
< 1 MIN READ
0
Magic, Miracle, or Molecular Mechanism (2)
8 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (5)
6 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (2)
7 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
Wasted Templeton Funding (4)
3 MIN READ
0
RNA splicing, genetic variation, and disease
2 MIN READ
0
Wasted Templeton Funding (3)
2 MIN READ
0
Wasted Templeton Funding (2)
2 MIN READ
0
From nothing to life and death everywhere
5 MIN READ
0
Molecular Diagnostics: What is unprotected life (4)
2 MIN READ
0
Molecular Microbial Ecology
8 MIN READ
0
Virus-driven sex differences?
2 MIN READ
0
Ricki Lewis’ Time Machine (4)
8 MIN READ
0
YEC compared to Perry Marshall’s opinions
4 MIN READ
0
Ricki Lewis’ Time Machine (3)
5 MIN READ
0
Creating nutrient-dependent life with enough genes to survive (2)
3 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Jay R. Feierman: twenty years of antagonism
5 MIN READ
0
Energy dependent RNA-mediated immunity (3)
8 MIN READ
0
Energy dependent RNA-mediated immunity (2)
10 MIN READ
0
Energy-dependent RNA-mediated immunity (1)
10 MIN READ
0
RNA-mediated DNA modifications
5 MIN READ
0
Science vs semantics
4 MIN READ
0
Bacteria see the light and they adapt (2)
5 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11 MIN READ
0
Bacteria see the light and they adapt
7 MIN READ
0
Will modern human populations adapt to the Zika virus?
5 MIN READ
0
Models of scientific literacy
3 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
Juvenile hormone links atoms to ecosystems
3 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
Finding peace and π in the light of H bond energy (2)
8 MIN READ
0
Perry Marshall: too much information for atheist PZ Myers
3 MIN READ
0
Assumptions prove ignorance
5 MIN READ
0
NORAD: air defense and defense against genomic entropy
7 MIN READ
0
Manufacturing fossil “evidence”
4 MIN READ
0
RNA-mediated theory killers (3)
7 MIN READ
0
RNA-mediated regulatory mechanisms link microbes to humans (3)
5 MIN READ
0
Essential pseudoscientific concepts of atheism
3 MIN READ
0
RNA-mediated theory killers
6 MIN READ
0
RNA-mediated everything
4 MIN READ
0
Plasma created by sunlight and RNA–mediated epigenetic heredity
2 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Neuroplasticity
4 MIN READ
0
Sensationalizing no new mechanism
2 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
Fossils vs cell types and the brain
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Controled Stem Cell Expansion
3 MIN READ
0
Human pheromone deniers: What’s next?
5 MIN READ
0
FREE* SAMPLE: Histone modification
4 MIN READ
0
Mystery machine vs model (2)
2 MIN READ
0
Epigenetic inheritance of stress-perturbed protein folding
2 MIN READ
0
Energy and evolution: another opinion?
2 MIN READ
0
Microbes to humans 2015 Nobel Prize
2 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Viruses come alive: Tree of life pseudoscience
6 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
A Darwinian pediatrician and expected life span
2 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Exosomes and the RNA-mediated future of medicine
5 MIN READ
0
Genome sequencing, cadherins, and quantum consciousness
6 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
A “new” code enables ecological adaptation
4 MIN READ
0
Information and communication (2)
6 MIN READ
0
Eibi Nevo gets it wrong
3 MIN READ
0
Ecology replaces the extended evolutionary synthesis
4 MIN READ
0
Viruses, amino acids, and somatic cell types
4 MIN READ
0
Hematopoiesis and practopoiesis
4 MIN READ
0
Koonin: viruses killed neo-Darwinism
3 MIN READ
0
Riding the wrong direction
3 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
Becoming biologically informed (2)
3 MIN READ
0
The RNA-mediated sum of our parts
2 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
Nutrient stress-induced RNA-mediated pathology
< 1 MIN READ
0
Creating and maintaining the human virome
2 MIN READ
0
Ignoring top-down causation
2 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
Ignoring systems complexity (it’s too complicated)
3 MIN READ
0
Computing via phosphorylation and fixation
3 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
How to find a “holy grail” under your nose
3 MIN READ
0
Physics, chemistry, light, and life
2 MIN READ
0
Epigenetics vs the fossil record
4 MIN READ
0
Thermodynamics and protein folding landscapes
2 MIN READ
0
RNA-mediated silencing of a chromosome
3 MIN READ
0
Feedback loops link insects to human brains
2 MIN READ
0
DNA Methylation and organized genomes (2)
10 MIN READ
0
Amino acid-dependent cell type differentiation
8 MIN READ
0
Mutisensory integration: watching the paradigm shift
12 MIN READ
0
Origin of life and cancer (1,2,3)
2 MIN READ
0
Silencing genes and serious scientists
3 MIN READ
0
The miRNA/mRNA balance: a suboptimal strategy?
2 MIN READ
0
Too many targets for theories
3 MIN READ
0
Methylation maintains cell type differences
3 MIN READ
0
Creating nothing but a theory
4 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Anti-entropic solar energy
5 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
Walk towards the light
< 1 MIN READ
0
Two types of microRNA are not double agents
2 MIN READ
0
Epigenetics Skeptism
5 MIN READ
0
Is DNA-directed transcription RNA-mediated?
2 MIN READ
0
Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs
2 MIN READ
0
Reverse phosphorylation
7 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
From 3-D to epigenetically-effected 4-D genome make-up
5 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
Nutritional epigenetics, exercise, and immune system integrity
4 MIN READ
0
Biological energy and a microbiome model of a light-driven time machine
3 MIN READ
0
Quantum Superpositions: let there be light
4 MIN READ
0
All of "like kind" in the (bigger) family
6 MIN READ
1
Environment epigenetically shapes the immune system
3 MIN READ
0
Beneficial microbes kill beneficial mutations
4 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
Unconstrained evolutionary innovability
4 MIN READ
0
Mutagenesis: Replacing facts with theories
5 MIN READ
0
From Hydra to humans vs a Lakatosian research program
4 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
Chemical ecology and RNA-mediated control of DNA loops
< 1 MIN READ
0
Jumping back: Science or Pseudoscience?
6 MIN READ
0
Extensive molecular evidence vs ridiculous theories
2 MIN READ
0
Dual genomes: exposing the evolution industry
5 MIN READ
0
Sackler Colloquium: Effects or AFFECTS on Behavior
2 MIN READ
0
Thermodynamic constraints and ecological adaptations sans evolution
6 MIN READ
0
RNA-mediated species specificity
2 MIN READ
0
Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
0
SNPs and millions of small variations in the human genome
3 MIN READ
0
More than a bag of chemicals?
2 MIN READ
0
Making sense of quotes scattered across disciplines
2 MIN READ
0
We need pattern recognition, not a prologue
6 MIN READ
0
Sexual differentiation of cell types in plants
2 MIN READ
0
A model of MHC 'evolution'
2 MIN READ
0
In theory, or supported by experimental evidence?
5 MIN READ
0
No understanding of biodiversity
2 MIN READ
0
Behavioral ecology: please continue to believe in our fantasies
3 MIN READ
0
2014 and 2004 Nobel Prize in Medicine
3 MIN READ
0
Forces of "Nature" limit dissemination of information
4 MIN READ
0
Metabolism, fixation, health or neurodegerative disorder
2 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Did our adapted mind evolve?
6 MIN READ
0
Miracles are not miracles to evolutionary theorists
2 MIN READ
0
A molecular visualizer of worthwhile molecular biology
2 MIN READ
0
Insect homology and diversity attributed to mutations
2 MIN READ
0
The quantum biology of consciousness
3 MIN READ
0
Don't tell the Creationists
2 MIN READ
0
Are pheromones responsible for human body odour assessment?
2 MIN READ
0
Evolutionarily innovative DNA mistakes?
< 1 MIN READ
0
Human pheromones and the definition of life
2 MIN READ
0
Adam’s rib: Pheromones and the adaptive evolution of human sexuality
2 MIN READ
0
Study results: Human pheromones influence human behavior
2 MIN READ
0
Exotic Pheromones and Concentrates
2 MIN READ
0
