Model vs theory: Progress report!
(click to enlarge)
On June 14, 2013,
1) Nutrient-dependent/pheromone-controlled adaptive evolution: a model and
2) Mutation-Driven Evolution
were published with divergent/opposite conclusions.
1) …the largest contributor to the development of our personal preferences may be the unconscious epigenetic effects of food odors and pheromones on hormones that organize and activate behavior. If so, the model represented here is consistent with what is known about the epigenetic effects of ecologically important nutrients and pheromones on the adaptively evolved behavior of species from microbes to man. Minimally, this model can be compared to any other factual representations of epigenesis and epistasis for determination of the best scientific ‘fit’.
2) …genomic conservation and constraint-breaking mutation is the ultimate source of all biological innovations and the enormous amount of biodiversity in this world. In this view of evolution there is no need of considering teleological elements.
Since June 14, 2013, no experimental evidence of nutrient energy-dependent biologically-based cause and effect has supported the constraint-breaking mutation claim. All experimental evidence of nutient energy-dependent biologically-based cause and effect has supported my claims about the role that RNA-mediated amino acid substitutions play in the nutrient-dependent pheromone-controlled organization and activation of supercoiled DNA in all living genera.
For example, on June 13, 2014, this article was published. Strong male bias drives germline mutation in chimpanzees
Abstract introduction:
Germline mutation determines rates of molecular evolution, genetic diversity, and fitness load.
My comment: This forced a change in the representations made by neo-Darwinian theorists. The change was reported as: Human & Chimp Genes May Have Diverged Twice As Long Ago As We Thought.
Less than one year after comparisons of our divergent conclusions could have been made, the problem with Nei’s misrepresentations in Mutation-driven evolution became clear. Supposedly, mutations must accumulate before they somehow cause a species-wide change, but examples of nutrient-dependent amino acid substitutions that alter cell type differentiation show how quickly fixation occurs via the physiology of reproduction. Thus, the time frame for species-wide fixation of mutations, which no experimental evidence suggests ever occurs, must be extended.
If animal models are used by theorists to teach people about the pseudoscientific nonsense that population geneticists invented to explain ecological adaptations, they must keep trying to link mutations from ecological variation to to energy-dependent ecological adaptations. However, a ssertions that the mutation-driven evolution of biodiversity is an established fact can be compared to what is known by serious scientists.
For example: Denis Noble: ” I would certainly go along with the view that gradual mutation followed by selection has not, as a matter of fact, been demonstrated to be necessarily a cause of speciation. Many of those who defend the modern synthesis would say, “Well, it has been.” But what you find when you look at the examples modern synthesists give is that they are for the gradual transition of one species into another in the historical record.”–
Replace the Modern Synthesis (Neo-Darwinism): An Interview With Denis Noble (5/9/14)
See also:
VIDEO
For comparison, see:
VIDEO
My comment: For an example of what happened in less than two years after comparisons
could have been made between the conclusions from 1)
Nutrient-dependent/pheromone-controlled adaptive evolution: a model and 2)
Mutation-Driven Evolution,
See:
Excerpt:
When proteins and sugars are mixed together and heated, new chemical compounds are formed
…our findings represent a real advance in the area of milk proteins and indicate that f-cMRP and cMRP could be recommended for use as potential antioxidants and cardioprotective ingredients for various functional, pharmaceutical, and dairy applications.
My comment: Nutrient energy-dependent thermodynamic cycles of protein biosynthesis and degradation are perturbed by virus-driven energy theft, which is why it is important to know that the bull sperm microRNAome and brain development in human infant is linked by the energy-dependent changes in microRNAs in breast milk, which are linked to the human microRNAome via everything currently known about metabolic networks and genetic networks in all living genera.
For an example of what happened in less than 3 years after comparisons could have been made between the conclusions from 1) Nutrient-dependent/pheromone-controlled adaptive evolution: a model and 2) Mutation-Driven Evolution,
See: Epigenetics and Genetics of Viral Latency (May 11, 2016)
Excerpt:
…viral latency is responsible for life-long pathogenesis and mortality risk…
My comment: Transgenerational epigenetic inheritance of virus-driven DNA damage is exemplified in the craniofacial deformities linked from the Zika virus to the development of the human brain.
See also: Kinds of top-down causation with my emphasis (June 1, 2016)
Excerpt:
The selection of native nucleic acid folding (an irreducible higher level variable) is an epigenetic effect,with broad implications for the evolution of plants and their viruses. The folding structure (a higher level variable) corresponds to an equivalence class of lower level sequences, and is the biologically relevant variable determining the selection that occurs. How do we demonstrate this top-down causation? This has been shown in detail experimentally by Shepherd et al. [171].
My comment: George Ellis admits that he knows about the experimental evidence of top-down causation that Shepherd et al. (2006) linked from energy-dependent biophysically constrained protein folding chemistry via nucleic acid folding conservation. The authors claimed that nucleic acid folding conservation:
…is the selective principle behind a high-frequency single-nucleotide reversion observed in a three-nucleotide mutated motif of the Maize streak virus replication associated protein (Rep) gene. In silico and in vitro studies showed that the three-nucleotide mutation adversely affected Rep nucleic acid folding, and that the single-nucleotide reversion [C(601)A] restored wild-type-like folding.
See also: In the present study, the effects of a two amino acid substitution (LLCNE to LLCLK) in the MSV RepA pRBR-interaction motif on both virus replication in maize culture cells and infectivity in maize were determined.
My comment: They linked a single energy-dependent nucleotide reversion to repair of DNA damage via the effects of a two amino acid substitution. Questions about what caused the DNA damage have only recently begun to be asked. Neo-Darwinian theorists simply assumed that mutations caused the DNA damage and that beneficial mutations were naturally selected. In other words, they assumed that all energy-dependent biodiversity could be explained in the context of the emergence of the first cell and mutation-driven evolution of all other cell types.
See also: The Broader View – with my emphasis (June 1, 2016)
Abstract:
The conclusion arising from the arguments given in this book is that there are other forms of causation than those encompassed by physics and physical chemistry alone, or even in genetics and neuroscience.
Excerpt:
…a discrete biological function can only rarely be attributed to an individual molecule, in the sense that the main purpose of haemoglobin is to transport gas molecules in the bloodstream. In contrast, most biological functions arise from interactions among many components. For example, in the signal transduction system in yeast that converts the detection of a pheromone into the act of mating , there is no single protein responsible for amplifying the input signal.
My comment: Ellis quotes from: Hartwell et al. (1999) From molecular to modular cell biology .
Conclusion:
Finally, we emphasize the importance of integrating experimental approaches with modelling and conceptual frameworks. The best test of our understanding of cells will be to make quantitative predictions about their behaviour and test them. This will require detailed simulations of the biochemical processes taking place within the modules. But making predictions is not synonymous with understanding. We need to develop simplifying, higher-level models and find general principles that will allow us to grasp and manipulate the functions of biological modules. The next generation of students should learn how to look for amplifiers and logic circuits, as well as to describe and look for molecules and genes (Box 3). Connecting different levels of analysis — from molecules, through modules, to organisms — is essential for an understanding of biology that will satisfy human curiosity.
My comment: There is no evidence presented in the book that Ellis is beginning to understand what is known to many others about energy-dependent biologically-based cause and effect. How could he not?
He already acknowledged the two most important claims I made in the context of Understanding and accounting for relational context is critical for social neuroscience
See the comments section:
This is absolutely correct and forms part of the larger concept that top-down causation is a key factor not just in the way the brain works but in broader contexts in biology and even physics.
Great links, thanks. I’m intrigued by your work on pheromones. It is just possible it might relate to the issue of primordial emotional systems…
I responded: Start with yeasts: Signaling Crosstalk: Integrating Nutrient Availability and Sex The nutrient-dependent production of the alpha mating pheromone exemplifies cell type differentiation at the advent of sexual reproduction, and when concentrated it elicits a luteinizing hormone (LH) response from the cultured pituitary cells of a mammal, the rat.
Tomorrow marks the third anniversary during which my review has been ignored by people like George Ellis, who still seem to be trying to defend ridiculous theories that have never integrated experimental evidence of biologically-based cause and effect.
See also: Destiny Isn’t Completely Written in Your Genes (June 10, 2016)
My comment:
“Your genes are profoundly important in determining your future, but the workings of the cell are complex and those sequences are not all that’s in play.”
Thanks for that clear conclusion. Finally, serious scientists can begin to make faster progress because others are being forced to admit that “…viral latency is responsible for life-long pathogenesis and mortality risk…” — See: “Epigenetics and Genetics of Viral Latency” (May 11, 2016)
Virus-driven theft of quantized energy causes the dysfunctions in the “…workings of the cell…”
See also: Is There a Fountain of Youth in Our DNA? by Brian Alexander
See:
Conclusion:
…the long gene list we discovered should serve as an important launching point for future studies into the still mysterious molecular mechanisms underlying learning and memory.
My comment: They link the conserved molecular mechanisms of epigenetically-effected RNA-mediated learning and memory to this representation of biologically-based cause and effect.
The honeybee already serves as a model organism for studying human immunity, disease resistance, allergic reaction, circadian rhythms, antibiotic resistance, the development of the brain and behavior, mental health, longevity, diseases of the X chromosome, learning and memory, as well as conditioned responses to sensory stimuli (Kohl, 2012 ). — Nutrient-dependent/pheromone-controlled adaptive evolution: a model (2o13).
See also: Study of individual neurons in flies reveals memory-related changes in gene activity
Excerpts:
…certain genes involved in creating long-term memories in the brain are the same ones that the eye uses for sensing light.
Although studies in other organisms, including humans, have detected sensory genes in areas of the brain unrelated to the sensory organ itself, this may be the first study to link these genes to memory formation.
My comment: Anna Di Cosmo, John Hewitt, Luca Turin, and Tim Bredy, will be able to link this from quantized energy-dependent changes in hydrogen-atom transfer in DNA base pairs in solution to ecological, social, neurogenic, and sociocognitive niche construction in species from microbes to humans via the conserved molecular mechanisms of RNA-mediated cell type differentiation they have learned about.
Unfortunately, many other researchers will not recognize that the quantized energy-dependent de novo creation of G protein-coupled receptors links chemotaxis to phototaxis in that order. That’s why others do not seem to know that the virus-driven theft of quantized energy is linked to all pathology. They’ve been taught that humans are primarily visual creatures in the context of ridiculous theories, like the one that links “Quantum Darwinism” from natural selection to the mutation-driven evolution of biodiversity.
NASA, Jesus & Templeton? (June 3, 2016)
Excerpt:
Religion has nothing to do with science and the NASA Astrobiology Program has squandered precious public funds — 5% of its annual budget — for an investigation into how the world’s religions might respond to the discovery of life on other planets. It has handed over $1.108M to a religious think tank, a nonprofit corporation with wealth management professionals on its board that already has in excess of $23M in assets.
My comment: Young earth creationists linked virus-driven energy theft to all pathology in “Viral Genome Junk Is Bunk”
I repeat: Paul M. Lieberman did that in “Epigenetics and Genetics of Viral Latency ”
See also: What is life when it is not protected from virus driven entropy
Templeton funds those who keep the focus on “Quantum Darwinism” instead of Schrodinger’s claims about the anti-entropic quantized energy of sunlight in “What is Life?” (1944). For example, the effects of virucidal UV light have been linked from RNA-mediated DNA repair to biophysically constrained energy-dependent cell type differentiation in all living genera.
When energy-dependent microRNA flanking sequences are linked to learning and memory, questions about the connection between morphological and behavioral biodiversity will be answered in the context of Darwin’s nutrient energy-dependent “conditions of life” and the physiology of reproduction, which links supercoiled DNA to the protection of all organized genomes from virus-driven energy theft and genomic entropy. I don’t think those answers will lie outside the context of what most creationists have been taught to believe.
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From E. coli to monkeys and mankind: Theories vs models (4)
2 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models (2)
6 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models
7 MIN READ
0
Food energy-dependent epigenetic adaptation (3)
3 MIN READ
0
Food energy-dependent epigenetic adaptation (2)
< 1 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (6)
8 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (5)
4 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (4)
2 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability
8 MIN READ
0
Energy as information and constrained endogenous RNA interference (4)
7 MIN READ
0
What energy source do proteins prefer?
6 MIN READ
0
Energy-dependent microRNA biogenesis
4 MIN READ
0
Draining the academic swamp of parasites
3 MIN READ
0
Dispensing with all pseudoscientific nonsense about evolution (1)
5 MIN READ
0
Virus-driven downsizing of the human brain (4)
2 MIN READ
0
Open Science: Closed to facts about microRNAs
6 MIN READ
0
Viruses in pathogenic variants disrupt alternative splicings (2)
3 MIN READ
0
Cytosis: Gameplay Runthrough
3 MIN READ
0
Synthetic RNA-based switches
2 MIN READ
0
Functionally interdependent editing and methylation
4 MIN READ
0
Cytosis: Biology Content
7 MIN READ
0
Cytosis: A Cell Biology Board Game
< 1 MIN READ
0
Sal Giardina: apologetics revisited
8 MIN READ
0
Virulence and your UTI
2 MIN READ
0
Life in your UV light-constrained galaxy
5 MIN READ
0
Thinking about energy is not radical re-thinking
6 MIN READ
0
Food for thought: Penrose v Ellis (1)
5 MIN READ
0
Energy-dependent pheromone-controlled entropy (3)
2 MIN READ
0
Energy-dependent pheromone-controlled entropy (4)
3 MIN READ
0
Proof: Sunlight is energy as information
< 1 MIN READ
0
Energy-dependent pheromone-controlled entropy (2)
6 MIN READ
0
The essence of precision medicine: drug targets or healthy longevity?
4 MIN READ
0
Allen Institute confirms food energy is information
6 MIN READ
0
RNA-mediated adult learning, memory, and neurogenesis
3 MIN READ
0
Ab initio cell wall invention, emergence, and evolution (1)
2 MIN READ
0
Theistic evolutionists fight back and lose (3)
4 MIN READ
0
Theistic evolutionists fight back and lose (2)
4 MIN READ
0
Theistic evolutionists fight back and lose
4 MIN READ
0
Young earth creationists refute theistic evolution
3 MIN READ
0
Bill Gates refutes theistic evolution (sequel)
8 MIN READ
0
Bill Gates refutes theistic evolution
4 MIN READ
0
Emily Witkin refutes theistic evolution
2 MIN READ
0
RNA editing refutes theistic evolution
4 MIN READ
0
Pseudoscientists fail to refute theistic evolution
4 MIN READ
0
Stuart Kauffman refutes theistic evolution
3 MIN READ
0
May the anti-entropic force of sunlight be with you
4 MIN READ
0
Francis S. Collins refutes theistic evolution
6 MIN READ
0
Energy is information. Objections over ruled. You’re fired!
7 MIN READ
0
George Church refutes theistic evolution (3)
5 MIN READ
0
George Church refutes theistic evolution (2)
2 MIN READ
0
George Church refutes theistic evolution
5 MIN READ
0
Bacteriophages prove evolution is a lie
2 MIN READ
0
Natural selection for codon optimality and quantum viruses
5 MIN READ
0
Physicists: Desperate Acts (revisited)
6 MIN READ
0
Energy as information and constrained endogenous RNA interference (3)
4 MIN READ
0
Energy as information and constrained endogenous RNA interference (2)
2 MIN READ
0
Virus-driven energy theft and premature death
3 MIN READ
0
Fighting for virus-driven pathology
5 MIN READ
0
ATP-dependent creation of RNA
2 MIN READ
0
Dobzhansky 1973 and precision medicine (5)
3 MIN READ
0
Atomic theory vs facts about hydrogen-atom transfer
4 MIN READ
0
Dobzhansky 1973 and Precision Medicine (2)
5 MIN READ
0
Trump’s appeal to common sense (2)
3 MIN READ
0
Science journalists or paid propagandists? (4)
6 MIN READ
0
Dobzhansky 1973 and precision medicine
6 MIN READ
0
Twisted theories and weaponized facts
3 MIN READ
0
Autophagy: from pre-mRNAs to microRNAs, enhancers, QTLs et al.
6 MIN READ
0
Mutations: the “driving force” behind human brain complexity?
6 MIN READ
0
Mutations: the "driving force" behind human brain complexity?
6 MIN READ
0
Science journalists or paid propagandists? (2)
3 MIN READ
0
Critical values expose virus-driven energy theft (2)
4 MIN READ
0
Critical values expose virus-driven energy theft
6 MIN READ
0
Anti-entropic energy and the “Music of Life”
3 MIN READ
0
Anti-entropic energy and the "Music of Life"
3 MIN READ
0
Evolved patterns of brain stimulation
3 MIN READ
0
Chirality is reality
6 MIN READ
0
Energy-dependent hydrogen bonds in supercoiled DNA
7 MIN READ
0
Energy-dependent chirality (2)
3 MIN READ
0
Energy-dependent chirality
6 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5 MIN READ
0
Vietnam Veterans and others with glioblastoma
3 MIN READ
0
Energy-dependent sensory maps (1996-2016)
5 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016
12 MIN READ
0
Energy-dependent oscillating gene networks organize life
4 MIN READ
0
2016 obfuscated facts about energy as information
5 MIN READ
0
More refutations of neo-Darwinian nonsense
7 MIN READ
0
Anti-entropic virucidal energy as information
10 MIN READ
0
Bio-functional information
3 MIN READ
0
Bird-brained theorists
< 1 MIN READ
0
Energy-dependent natural translational selection
4 MIN READ
0
Autophagy is the antiphage defense strategy
3 MIN READ
0
Energy-dependent de novo creation and neurogenesis (2)
5 MIN READ
0
Energy-dependent de novo creation and neurogenesis
7 MIN READ
0
Theories vs facts about polycombic adaptation
3 MIN READ
0
Tasting light links energy from creation to adaptation
9 MIN READ
0
Politicized science: The demise of RNA-mediated.com?
3 MIN READ
0
Combating evolution: Battlefield medicine vs politicized science
6 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Metabolic Phenotyping Research
2 MIN READ
0
Phylogenetic similarity sans energy
2 MIN READ
0
Happy biophysically constrained Thanksgiving (in the USA)
3 MIN READ
0
De novo gene creation: Ignoring the experimental evidence
7 MIN READ
0
Light, behavior and autophagy, a gender-specific risk factor
4 MIN READ
0
Energy-dependent purifying selection / autophagy (2)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (3)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (5)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (6)
3 MIN READ
0
Energy-dependent purifying selection / autophagy
2 MIN READ
0
Optogenetics: Let there be virucidal light!
2 MIN READ
0
Base pairs, amino acids and phenotypes
10 MIN READ
0
Survivors of RNA-mediated terrorism
5 MIN READ
0
Building delicious base pairs in class. It’s elementary Watson and Crick
3 MIN READ
0
Building delicious base pairs in class. It's elementary Watson and Crick
3 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (8)
4 MIN READ
0
Energy-dependent maternal-to-zygotic transition
6 MIN READ
1
Virus-driven mutation or amino acid substitution
5 MIN READ
0
Epigenetically effected energy-dependent fluorescence (2)
6 MIN READ
0
Epigenetically effected energy-dependent fluorescence
5 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (7)
3 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (5)
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (3)
< 1 MIN READ
0
Top-down adaptation vs bottom-up evolution
6 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
Polycombic ecological adaptation as a science, not a theory
3 MIN READ
0
Attacking Young Earth Creationists
5 MIN READ
0
80 years of causal analysis (1936 – 2016)
11 MIN READ
0
Did evolution autophosphorylate your kinases? (3)
2 MIN READ
1
Predictable idiosyncratic evolved convergence
3 MIN READ
0
The natural success of RNAi and failed treatment
7 MIN READ
0
Hecatombic evolution via oncocers and oncohistones
9 MIN READ
0
Did evolution autophosphorylate your kinases? (2)
5 MIN READ
1
Did evolution autophosphorylate your kinases?
5 MIN READ
1
Nutrient-dependent autophagy
3 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy (2)
6 MIN READ
0
The last RNA-mediated theory killer (2)
7 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy
3 MIN READ
0
Life is energy-dependent task management (2)
3 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
Hypothesis free pseudoscience vs facts (5)
6 MIN READ
0
Hypothesis free pseudoscience vs facts (4)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (2)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (1)
5 MIN READ
0
Base pairs, olfaction and RNA thermometers
4 MIN READ
0
Chromatin: The structure of DNA (2)
8 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
A working model of “captured” genes
6 MIN READ
0
The Aquatic Ape / Waterside Ape divergence
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
Displays of ecological adaptation (2)
3 MIN READ
0
Displays of ecological adaptation
2 MIN READ
0
Unconstrained mutations, Zika virus, Kallmann’s syndrome
4 MIN READ
0
Virus-driven energy theft causes cancer
2 MIN READ
0
Linking RNA structure to function
3 MIN READ
0
The Aquatic Ape: New evidence?
4 MIN READ
0
Plant microRNAs slow virus-driven aging
3 MIN READ
0
Protecting 4 billion people from virus-driven entropy
< 1 MIN READ
0
Increased soil pH and nutrient availability
4 MIN READ
0
Energy-dependent cellular communication
3 MIN READ
0
Virus-driven energy theft: honeybee model
3 MIN READ
0
Antithetical conclusions (7)
3 MIN READ
0
Antithetical conclusions (5)
4 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
RNAi: From magic bullet to billion dollar baby
4 MIN READ
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (3)
< 1 MIN READ
0
Biophysically constrained cell type differentiation
3 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
Q and A: Energy-dependent cell type differentiation
10 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
The end of neo-Darwinism
5 MIN READ
0
The Origin of Information (2)
6 MIN READ
0
The tipping point? 50,000 publications (5)
3 MIN READ
0
RNA-mediated programming of E.coli
< 1 MIN READ
0
Did “Nature” kill Steve Jobs? (2)
6 MIN READ
0
Did “Nature” kill Steve Jobs?
3 MIN READ
0
Virus-driven downsizing of the human brain (2)
< 1 MIN READ
0
Virus-driven downsizing of the human brain
2 MIN READ
0
MicroRNAs and sexual orientation
8 MIN READ
0
RNA methylation, learning, memory and behavior,
< 1 MIN READ
0
Innate immunity and multiplexing
7 MIN READ
0
RNA methylation (2)
7 MIN READ
0
Amino acids and virus penetration
3 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
RNA methylation
2 MIN READ
0
Masters of deception about nature (2)
7 MIN READ
0
Masters of deception about nature
8 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
Cracking the Olfactory Code?
5 MIN READ
0
RNA methylation, behavior, and disease
6 MIN READ
0
Modelling life scientifically: RNA-mediated events
12 MIN READ
0
Energy-dependent RNA methylation (10)
4 MIN READ
0
Energy-dependent RNA methylation (8)
4 MIN READ
0
Energy-dependent RNA methylation (6)
9 MIN READ
0
Energy-dependent RNA methylation (3)
10 MIN READ
0
Energy-dependent RNA methylation (2)
5 MIN READ
0
Thermotolerance and longevity (2)
3 MIN READ
0
Energy-dependent biodiversity (3)
7 MIN READ
0
Countdown to Genetics and Genomics
< 1 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
Wasted Templeton Funding (4)
3 MIN READ
0
MicroRNAs and/or QTLs: Who buried what?
2 MIN READ
0
Wasted Templeton Funding (3)
2 MIN READ
0
A bumper crop of virus-infected weeds and people
2 MIN READ
0
Magic, Miracle, or Molecular Mechanism?
10 MIN READ
0
Molecular Diagnostics: What is unprotected life (4)
2 MIN READ
0
Molecular Diagnostics: What is unprotected life (3)
5 MIN READ
0
Molecular Microbial Ecology
8 MIN READ
0
Molecular Diagnostics: What is unprotected life? (2)
7 MIN READ
0
Molecular Diagnostics: What is unprotected life?
2 MIN READ
0
Ricki Lewis’ Time Machine (4)
8 MIN READ
0
Creating and/or programming the immune system
< 1 MIN READ
0
Ricki Lewis’ Time Machine (3)
5 MIN READ
0
Creating nutrient-dependent life with enough genes to survive
3 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Virus-driven disorder prevention and health promotion
6 MIN READ
0
Jay R. Feierman: twenty years of antagonism
5 MIN READ
0
Energy dependent RNA-mediated immunity (6)
5 MIN READ
0
Do not miss the misrepresentations
2 MIN READ
0
Energy dependent RNA-mediated immunity (5)
4 MIN READ
0
Energy dependent RNA-mediated immunity (4)
6 MIN READ
0
Energy dependent RNA-mediated immunity (3)
8 MIN READ
0
RNA-mediated DNA modifications
5 MIN READ
0
Science vs semantics
4 MIN READ
0
Bacteria see the light and they adapt (2)
5 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands (2)
3 MIN READ
0
Bringing RNA back to epigenetics (20 years later)
11 MIN READ
0
Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11 MIN READ
0
Bacteria see the light and they adapt
7 MIN READ
0
Organic Compounds and the Miracle of Smell and Taste
7 MIN READ
0
Despicable fools?
4 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Cytogenetic approaches link biosystems to ecosystems
3 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (5)
10 MIN READ
0
The radical pair mechanism of ecological speciation
3 MIN READ
0
Center stage RNA-mediated events (since 1996)
3 MIN READ
0
The unoffically uninvited
3 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs (4)
4 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
Another failed rescue attempt
5 MIN READ
0
Stress-induced energy-dependent DNA repair
4 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Ecological genomics: teleophobes respond (too late)
10 MIN READ
0
Intelligent RNAs vs evolved genes
2 MIN READ
0
Ecological law, cooperation, and DNA repair
4 MIN READ
0
Amino acid substitutions, stress, and human behavior
3 MIN READ
0
RNA-mediated theory killers (11) (12) (13) (14) (15)
7 MIN READ
0
RNA methylation, RNA-directed DNA methylation, learning and memory
3 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Epigenetic (re)programming of behavior (3)
5 MIN READ
0
Perry Marshall: too much information for atheist PZ Myers
3 MIN READ
0
Assumptions prove ignorance (2)
5 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
Assumptions prove ignorance
5 MIN READ
0
NORAD: air defense and defense against genomic entropy
7 MIN READ
0
Life history transitions and RNA-mediated survial
2 MIN READ
0
Did Dobzhansky see the UV light of creation?
10 MIN READ
0
Researchers rename, reshuffle, and reveal their ignorance
3 MIN READ
0
RNA-mediated theory killers (6) (7) (8) (9) (10)
5 MIN READ
0
Manufacturing fossil “evidence”
4 MIN READ
0
RNA-mediated theory killers (4)
9 MIN READ
0
A million dollar paradox?
2 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (4)
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs
9 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair
2 MIN READ
0
Plasma created by sunlight and RNA–mediated epigenetic heredity
2 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Cell type differentiation: atoms to ecosystems
2 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
Models are not theories (2)
2 MIN READ
0
MicroRNA-encoded behavior
7 MIN READ
0
Fossils vs cell types and the brain
3 MIN READ
0
Can veterans and other prisoners escape pseudoscience?
2 MIN READ
0
RNA central and RNA-mediated.com
6 MIN READ
0
Designing, engineering, and protecting biodiversity
3 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Neo-Darwinian logic is nonsense
3 MIN READ
0
700 million years of evolution?
5 MIN READ
0
RNA-mediated retrotransposon-mediated biodiversity
3 MIN READ
0
Preventing genomic entropy
4 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
Theorists have not seen the light (2)
3 MIN READ
0
Hijacked light energy and vertebrate pathology
4 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
The creation and activation of GPCRs
4 MIN READ
0
A 5-10K comparison of design principles to evolution
3 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Pathology: Eating and breathing viruses
2 MIN READ
0
Exosomes and the RNA-mediated future of medicine
5 MIN READ
0
From fertilization to RNA-mediated events and back
2 MIN READ
0
Phytochemical link from the sun to cell types
2 MIN READ
0
New anti-entropic microbes
3 MIN READ
0
Natural selection: an anti-entropic force?
2 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Creating genes and species
3 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
The “great filter” is an epigenetic trap
4 MIN READ
0
Information and communication (2)
6 MIN READ
0
Unraveling evolutionary pseudoscience
2 MIN READ
0
From “Blood Music” to Evolution 2.0
5 MIN READ
0
Ecological speciation vs revised evolutionary syntheses
6 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
Light -induced nucleic acid-mediated gene duplication?
< 1 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
Big Bang Cosmology vs Reality
< 1 MIN READ
0
RNA-mediated morphological AND behavioral phenotypes
2 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Is photic-zone ribosomal diversity linked to all biodiversity?
2 MIN READ
0
Riding the wrong direction
3 MIN READ
0
Decreased phenotypic variation: Faith in Facts
7 MIN READ
1
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
Celebrating independence from ridiculous theories
3 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
RNA-mediated cell type differentiation: Honeybee
< 1 MIN READ
0
Amino acid substitutions are not mutations
2 MIN READ
0
What I cannot create I eliminate from discussion
3 MIN READ
0
Creating and maintaining the human virome
2 MIN READ
0
Living the life that randomness created? (Sarcasm alert)
3 MIN READ
0
microRNAs, glycosylation, and genomes
4 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Viruses and the human-like microbiome
3 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
A lighting requirement for life
11 MIN READ
3
Scientists lose. A sci-fi author gains credibility
2 MIN READ
0
Vitamin B3 and DNA repair
4 MIN READ
0
Bees and primates automagically evolve
3 MIN READ
0
Ignoring systems complexity (it’s too complicated)
3 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Protein isoforms do not evolve
3 MIN READ
0
Tissue type variation and expression of genes
< 1 MIN READ
0
Chance mutations — not natural selection
5 MIN READ
0
Viruses in gut microbes
4 MIN READ
0
How to find a “holy grail” under your nose
3 MIN READ
0
Physics, chemistry, light, and life
2 MIN READ
0
pH, water, amino acids and protein folding
4 MIN READ
0
An epigenetic mark links algae, worms, and flies
2 MIN READ
0
Pathology constrains X-linked evolution
2 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
Nutrient-dependent RNA interference
4 MIN READ
0
A genetic variant refutes neo-Darwinism
6 MIN READ
0
MicroRNAs and invasive phenotypes
< 1 MIN READ
0
Nutrient-dependent microRNAs control cell types
6 MIN READ
0
Life: conserved ion and amino acid transporters
3 MIN READ
0
MicroRNAs and memory
< 1 MIN READ
0
Deeply ingrained thoughts
< 1 MIN READ
0
UV-light mutations and gene loss (not gain)
5 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
RNA directed DNA methylation and cell types
4 MIN READ
0
Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs
2 MIN READ
0
RNA-mediated repurposing in microbes and adaptations in primate brains
2 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
From 3-D to epigenetically-effected 4-D genome make-up
5 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
An epigenetic trap (the prequel)
5 MIN READ
0
Imagining that data historically supports evolutionary theory
7 MIN READ
0
What if Darwin was not still dead?
2 MIN READ
0
Military combat training to fight disease (2)
3 MIN READ
0
Epigenetic effects of viruses on cellular homeostasis (2)
2 MIN READ
0
Quantum physics, quantum biology, and quantum consciousness
4 MIN READ
0
How fast can evolutionary theory be changed?
5 MIN READ
0
Quantum Superpositions: let there be light
4 MIN READ
0
Sneaking up from behind (2)
3 MIN READ
0
Mute points: most are afraid to mention them
6 MIN READ
0
All of "like kind" in the (bigger) family
6 MIN READ
1
Environment epigenetically shapes the immune system
3 MIN READ
0
Beneficial microbes kill beneficial mutations
4 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
A single amino acid substitution differentiates cell types of E. coli
3 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
Removing natural selection; reshaping the horse; adjusting evolutionary theory
4 MIN READ
0
Atoms to ecosystems: Evolutionary theory vs the coelacanth
6 MIN READ
0
Jumping back: Science or Pseudoscience? (2)
2 MIN READ
0
Glycine and GnRH: Am I being pedantic?
4 MIN READ
0
Extensive molecular evidence vs ridiculous theories
2 MIN READ
0
Dual genomes: exposing the evolution industry
5 MIN READ
0
Thermodynamic constraints and ecological adaptations sans evolution
6 MIN READ
0
Eliminating correlations from evolutionary ecology
6 MIN READ
0
RNA-mediated species specificity
2 MIN READ
0
Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
0
Biologists puzzled by evolved RNAs and decaying DNA
6 MIN READ
0
More than a bag of chemicals?
2 MIN READ
0
Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
0
Making sense of quotes scattered across disciplines
2 MIN READ
0
Complex behaviors of cell types in cancer
6 MIN READ
0
De novo DNA methylation?
3 MIN READ
0
We need pattern recognition, not a prologue
6 MIN READ
0
Pharmacogenomics
3 MIN READ
0
From deep time into real time: What evolutionary processes?
10 MIN READ
0
In theory, or supported by experimental evidence?
5 MIN READ
0
It’s cell type differention, not cell fate determination (2)
3 MIN READ
0
Are evolutionary theorists 'nob ends'?
5 MIN READ
2
ALPHA GENOMIX
7 MIN READ
2
No excuses: Creation and the meaning of organismal complexity
7 MIN READ
0
Nutrient-dependent gene duplication in plants (but not animals?)
4 MIN READ
0
Evolutionary theorists justify fear of the Ebola viruses
2 MIN READ
0
Evolutionary theorists and evolutionary theists live under rocks
< 1 MIN READ
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No understanding of biodiversity
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2014 and 2004 Nobel Prize in Medicine
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RNA-mediated events: chromosomal rearrangements and genomic rearrangements
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RNA-mediated genetic engineering (Part 2)
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RNA-mediated events are not a matter of faith
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Color vision refutes the evolutionary dogma of gene duplication
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Unassailable evidence vs assumptions
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Forces of "Nature" limit dissemination of information
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Genomic surveillance ends our world of RNA-mediated ecological adaptations
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Physics, Chemistry, and Molecular biology (PCMb)
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Physics denied; pseudoscientific nonsense accepted
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Ecological variation and niche construction: 1, 2, 3
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Epigenetically-effected metabolic shifts and ecological adaptations
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Evolving DNA before RNA
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Stop evolutionary theorists. Kill cancers
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Did our adapted mind evolve? (Revisited)
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Did our adapted mind evolve?
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RNA-directed DNA methylation and RNA-mediated events
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Miracles are not miracles to evolutionary theorists
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Mathematical model: microRNA and epigenetic regulation
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Seemingly futile cycles are not thermodynamically futile
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Do bacterial proteins evolve?
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Probable changes in connectivity
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Memory of repression and memory of behavior (2)
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Memory of repression and memory of behavior
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Quantum physics meets Evolutionary Psychology News
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Nutrient-dependent pheromone-controlled exercise-induced physiques
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A molecular visualizer of worthwhile molecular biology
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RNA-mediated species diversification from microbes to primates
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Some neuroscientists think a mutation led to human language development
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Is the problem an internet echo or Feierman's ethics?
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RNA-mediated ecological adaptation is not evolution
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Exploding genomes and chromosomal rearrangements via RNA-mediated events
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Mechanisms that are not understood increase clarity
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Evolutionary heritage or ecological adaptation? Racism versus reality
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Insect homology and diversity attributed to mutations
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Biophysically constrained beginnings of RNA and DNA
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Comparing divergent model organisms
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A microRNA-mediated mechanism that is epigenetically inherited
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Epimutations: Attacking pseudoscientific dogmas
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Order and disorder: Ecological adaptations not mutations
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microRNAs differentiate neuronal cell types
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microRNAs and species relationships
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Drunks and Monkeys: Pseudoscientific nonsense
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The quantum biology of consciousness
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Behavior is receptor-mediated
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Genes and Race: Human History?
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Ecologically linked adapted ants and brains
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Darwinian theories vs Darwin's facts
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Chromosomal rearrangements and ecological adaptations
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The wrong picture of our evolution
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Jay R. Feierman
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Don't tell the Creationists
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Targeting a cancer gene
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Pulses of olfactory/pheromonal input
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Social experiences epigenetically effect gene networks
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Evolution: innovations may have non-adaptive origins (sans mutations)
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Nutrient-dependent / pheromone-controlled social structure
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Epistasis as the primary factor in molecular evolution
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Epigenetic maintenance of transcription / neuronal migration
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Epigenetic effects underlie sexual preferences IV
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A newly discovered hypothalamic neurogenic niche in the brain
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MicroRNA binds messenger RNA: Adaptive Evolution
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Sex differences in Alzheimer's and everything else
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Sex differences in Alzheimer’s and everything else
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The logic of gene regulatory networks
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Creating new genes (and controlling diversity)
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The end of random mutations theory
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Epigenetic effects of viruses on cellular homeostasis
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Human pheromones: epigenetic effects
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Nobel laureate challenges psychologists to clean up their act
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“Just-So” stories vs scientific explanations
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Human pheromones and the epigenetic effects of isolation
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Natural selection and the behavior of whole organisms
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Natural selection: New insights are unlikely
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Human pheromones: an epigenetic continuum from microbes to mammals
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The Epigenetics of Drug Development and Cholesterol Levels
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Epigenetic alterations due to stress
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Human pheromones and autism spectrum disorders
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Human pheromones, the social brain and simple math computations
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Children’s healthy diets lead to healthier IQ
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Human pheromones and IQ via neurogenic and socio-cognitive niche construction
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Human pheromones, nutrition, DNA, epigenetics
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Niche construction: ecological, social, neurogenic, and socio-cognitive
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Human pheromones in business strategy
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Human pheromones, social deprivation, and brain growth
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Human Pheromones and Free Will: a response to Gazzaniga
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Nutrient mixture and memory in patients with early Alzheimer’s
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Human pheromones and multi-level selection
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Bee research, human sweet perception, human pheromones, and metabolic disorders
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Human pheromones and the viruses that make us
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A detailed model of physical reality and natural selection (722 words)
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Evolution of the nervous system: conserved GnRH
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Human Pheromones and Comparative Epigenomics
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Aging Is Recorded in Our Genes
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Human Pheromone Facts and the Out of Africa Theory
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Smelling the difference between young and old
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Human pheromones and the visual appeal of other people (Part Four)
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A thought experiment
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No New Neurons for Smell?
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A nutrient chemical and pheromone-dependent neurogenic niche
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Human pheromone- and nutrient-dependent brain development and behavior
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Human pheromones and the visual appeal of other people (Part Two)
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Human Pheromones in Socioaffective Neuroscience & Psychology
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The cause of colony collapse could be a message for all of us
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Human Pheromones: 2010 Powerpoint slides and 2011 poster presentation
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Epigentics and the baby connectome
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Misrepresentations of biologically based cause and effect:
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Cause and effect in biology
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Baiting evolutionary psychologists and others who damn religion
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The Demise of Guys
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Pheromones and detectable odors
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The “yuck” factor: aversion to social odors?
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Human pheromones: social odors and food odors
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Pheromones and a realistic model of sexual differentiation
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A lesser role for olfaction and pheromones in humans?
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Creating a Myth
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Social selection: genetic contribution of viruses to life on earth
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Pheromones and Physiology: Faculty of 1000: Naturally Selected
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Molecular biology and social science theory
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Presentation on Human Pheromones delivered on August 3, 2010
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