Energy-dependent cellular communication
(click to enlarge)
Communication shapes sensory response in multicellular networks
Significance
Cells routinely sense and respond to their environment, and they also communicate with each other. Exactly how communication impacts sensing remains poorly understood. We study a population of fibroblast cells that responds to a chemical stimulus (ATP) and communicates by molecule exchange. Combining experiments and mathematical modeling, we find that cells exhibit calcium oscillations in response to not only the ATP stimulus but also, increased cell–cell communication. Our results show that, when cells are together, their sensory responses reflect not just the stimulus level but also, the degree of communication within the population.
Reported as: Research outlines cellular communication processes that make life possible
In light of these developments, our results suggest that cell density, via gap junctional communication and nonlinear signaling dynamics, can impact cellular function, similar to so-called dynamical quorum sensing (46–48).
Quorum sensing is nutrient energy-dependent and pheromone-controlled via epigenetic links to RNA-mediated amino acid substitutions and cell type differentiation in all living genera. They link energy-dependent cellular communication in all living genera to the ability of a baseball player to hit a pitch via links to the de novo creation of photoceptors. The creation of all receptors is energy-dependent and occurs only in the context of the creation of odor receptors.
Their results can be placed into the context of the de novo creation of G protein-coupled receptors (GPCRs), which links chemotaxis and phototaxis to energy-dependent biologically-based cause and effect. In that context, virus-driven energy theft links mutations to all pathology.
They have killed all neo-Darwinian theories with experimental evidence that links Einstein’s math to Schrodinger’s physics and Dobzhansky’s claims about amino acid substitutions. RNA-mediated amino acid substitutions link chemotaxis and phototaxis to energy-dependent fixation of cell type differences in all cell types of all individuals of all living genera.
See also:
A Billion Genes and Not One Beneficial Mutation
His lab experience with protein folds leads him to the empirically supported conclusion that the sequence space for proteins (and the genes that encode them) is so fantastically large that blind search is hopelessly inadequate to find the good variants. And since natural selection cannot invent things, that’s all it has to work with. Remember, mutations are random. Finding good mutations is far less probable in a blind search than throwing a dart blindfolded from space and hitting a pre-specified target one millimeter in diameter. When the search space is “fantastically large,” adding more darts won’t help. You run into physical limits of time and energy cost.
Codon identity regulates mRNA stability and translation efficiency during the maternal-to-zygotic transition
The amino acid optimality code (Fig 6) provides an alternative perspective on sequence changes between paralogs in evolution and human disease.
Natural selection for energy-dependent codon usage and RNA-mediated protein folding chemistry has since linked two earlier reports to all cell type differentiation in all individuals of all living genera.
… viral latency is responsible for life-long pathogenesis and mortality risk…
The anti-entropic force of virucidal ultraviolet light (UV) links guanine–cytosine (G⋅C) Watson–Crick base pairing from hydrogen-atom transfer in DNA base pairs in solution to supercoiled DNA, which protects the organized genomes of all living genera from virus-driven entropy. For example, protection of DNA from permanent UV damage occurs in the context of photosynthesis and nutrient-dependent RNA-directed DNA methylation, which links RNA-mediated amino acid substitutions to DNA repair. In the context of thermodynamic cycles of protein biosynthesis and degradation, DNA repair enables the de novo creation of G protein coupled receptors (GPCRs). Olfactory receptor genes are GPCRs. The de novo creation of olfactory receptor genes links chemotaxis and phototaxis from foraging behavior to social behavior in species from microbes to humans. Foraging behavior links ecological variation to ecological adaptation in the context of this atoms to ecosystems model of biophysically constrained energy-dependent RNA-mediated protein folding chemistry. Protein folding chemistry links nutrient-dependent microRNAs from microRNA flanking sequences to energy transfer and cell type differentiation in the context of adhesion proteins, and supercoiled DNA that protects all organized genomes from virus-driven entropy.
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0
Sudden death indel polymorphism
4 MIN READ
0
Anti-entropic virucidal energy as information
10 MIN READ
0
Bio-functional information
3 MIN READ
0
Bird-brained theorists
< 1 MIN READ
0
Expunging the distinguished public
2 MIN READ
0
Explorers who do not know what is known (2)
6 MIN READ
0
Explorers who do not know what is known
4 MIN READ
0
Energy-dependent natural translational selection
4 MIN READ
0
Autophagy is the antiphage defense strategy
3 MIN READ
0
Energy-dependent de novo creation and neurogenesis (2)
5 MIN READ
0
Energy-dependent de novo creation and neurogenesis
7 MIN READ
0
Theories vs facts about polycombic adaptation
3 MIN READ
0
Tasting light links energy from creation to adaptation
9 MIN READ
0
Politicized science: The demise of RNA-mediated.com?
3 MIN READ
0
Combating evolution: Battlefield medicine vs politicized science
6 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Metabolic Phenotyping Research
2 MIN READ
0
Phylogenetic similarity sans energy
2 MIN READ
0
Happy biophysically constrained Thanksgiving (in the USA)
3 MIN READ
0
De novo gene creation: Ignoring the experimental evidence
7 MIN READ
0
Energy-dependent coulombic, autophagic, polycombic healthy longevity
4 MIN READ
0
Light, behavior and autophagy, a gender-specific risk factor
4 MIN READ
0
Controlled amino acid treatment of all pathology
4 MIN READ
0
Energy-dependent purifying selection / autophagy (2)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (3)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (4)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (5)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (6)
3 MIN READ
0
Energy-dependent purifying selection / autophagy
2 MIN READ
0
Optogenetics: Let there be virucidal light!
2 MIN READ
0
Base pairs, amino acids and phenotypes
10 MIN READ
0
Survivors of RNA-mediated terrorism
5 MIN READ
0
RNA-mediated terrorism
< 1 MIN READ
0
Building delicious base pairs in class. It’s elementary Watson and Crick
3 MIN READ
0
Building delicious base pairs in class. It's elementary Watson and Crick
3 MIN READ
0
RNA-mediated “repurposing” is autophagy
2 MIN READ
0
RNA-mediated "repurposing" is autophagy
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (8)
4 MIN READ
0
Energy-dependent maternal-to-zygotic transition
6 MIN READ
1
Virus-driven mutation or amino acid substitution
5 MIN READ
0
Epigenetically effected energy-dependent fluorescence (2)
6 MIN READ
0
Epigenetically effected energy-dependent fluorescence
5 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (7)
3 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (5)
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (3)
< 1 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (2)
2 MIN READ
0
From precis to pre-mRNA and proof of concept in F1, F2, F3
6 MIN READ
0
From Precis to Proof in 6000 years (2)
5 MIN READ
0
From Precis to Proof in 6000 years
9 MIN READ
0
Coulombic interactions facilitate polycombic adaptation
5 MIN READ
0
Top-down adaptation vs bottom-up evolution
6 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (3)
< 1 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (2)
3 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
Demoncrats fight polycombic ecological adaptation
4 MIN READ
0
Polycombic ecological adaptation as a science, not a theory
3 MIN READ
0
Biological evolution as a philosophy, not a science
6 MIN READ
0
Attacking Young Earth Creationists
5 MIN READ
0
80 years of causal analysis (1936 – 2016)
11 MIN READ
0
The human virome (revisited)
4 MIN READ
0
Carl Woese was wrong
2 MIN READ
0
The natural success of RNAi and failed treatment
7 MIN READ
0
Pheromone-controlled autophagy
4 MIN READ
0
Hecatombic evolution VS polycombic ecological adaptation
3 MIN READ
0
Virus-mediated hecatombic evolution
2 MIN READ
0
Hecatombic evolution via oncocers and oncohistones
9 MIN READ
0
Did evolution autophosphorylate your kinases? (2)
5 MIN READ
1
Did evolution autophosphorylate your kinases?
5 MIN READ
1
Nutrient-dependent autophagy
3 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy (2)
6 MIN READ
0
The last RNA-mediated theory killer (2)
7 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy
3 MIN READ
0
Life is energy-dependent task management (4)
2 MIN READ
0
Life is energy-dependent task management (2)
3 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
Hypothesis free pseudoscience vs facts (5)
6 MIN READ
0
Hypothesis free pseudoscience vs facts (4)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (3)
3 MIN READ
0
Hypothesis free pseudoscience vs facts (2)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (1)
5 MIN READ
0
The last RNA-mediated theory killer
< 1 MIN READ
0
Base pairs, olfaction and RNA thermometers
4 MIN READ
0
Chromatin: The structure of DNA (2)
8 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
A working model of “captured” genes
6 MIN READ
0
DNA repair via junk DNA (2)
5 MIN READ
0
The Aquatic Ape / Waterside Ape divergence
6 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
Displays of ecological adaptation (2)
3 MIN READ
0
DNA repair via junk DNA (1)
5 MIN READ
0
Displays of ecological adaptation
2 MIN READ
0
Unconstrained mutations, Zika virus, Kallmann’s syndrome
4 MIN READ
0
Linking RNA structure to function
3 MIN READ
0
Exosomes, Inflammatory Disease, Pathogenesis, Treatment
< 1 MIN READ
0
How did the innate immune system evolve?
4 MIN READ
0
The Aquatic Ape: New evidence?
4 MIN READ
0
Plant microRNAs slow virus-driven aging
3 MIN READ
0
Protecting 4 billion people from virus-driven entropy
< 1 MIN READ
0
Increased soil pH and nutrient availability
4 MIN READ
0
Lawless evolution: No physics
4 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Antithetical conclusions (7)
3 MIN READ
0
Antithetical conclusions (5)
4 MIN READ
0
Antithetical conclusions (6)
3 MIN READ
0
Anthetical conclusions (2)
5 MIN READ
0
Anthetical conclusions
3 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
RNAi: From magic bullet to billion dollar baby
4 MIN READ
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
Pseudoscientists ignore what serious scientists prove
6 MIN READ
0
GC-rich neo-Darwinian train wreck
5 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (3)
< 1 MIN READ
0
Biophysically constrained cell type differentiation
3 MIN READ
0
From angstroms to ecosystems
7 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
Virus-driven downsizing of the human brain (3)
4 MIN READ
0
Do weak bosons evolve into leptons?
4 MIN READ
0
Q and A: Energy-dependent cell type differentiation
10 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
The end of neo-Darwinism
5 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity
4 MIN READ
0
The Origin of Information (2)
6 MIN READ
0
Did “Nature” kill Steve Jobs? (3)
10 MIN READ
0
Funding the Human Genome Project-Write
2 MIN READ
0
RNA-mediated programming of E.coli
< 1 MIN READ
0
Did “Nature” kill Steve Jobs? (2)
6 MIN READ
0
Did “Nature” kill Steve Jobs?
3 MIN READ
0
Virus-driven downsizing of the human brain (2)
< 1 MIN READ
0
RNA methylation (revisited)
< 1 MIN READ
0
Placing boundaries where none exist
< 1 MIN READ
0
Virus-driven downsizing of the human brain
2 MIN READ
0
MicroRNAs and sexual orientation
8 MIN READ
0
RNA methylation, learning, memory and behavior,
< 1 MIN READ
0
Innate immunity and multiplexing
7 MIN READ
0
RNA methylation (2)
7 MIN READ
0
Amino acids and virus penetration
3 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
RNA methylation
2 MIN READ
0
Model vs theory: Progress report!
8 MIN READ
0
Masters of deception about nature (2)
7 MIN READ
0
Masters of deception about nature
8 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
Cracking the Olfactory Code?
5 MIN READ
0
RNA methylation, behavior, and disease
6 MIN READ
0
Modelling life scientifically: RNA-mediated events
12 MIN READ
0
Energy-dependent RNA methylation (9)
2 MIN READ
0
Energy-dependent RNA methylation (10)
4 MIN READ
0
Energy-dependent RNA methylation (8)
4 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (6)
9 MIN READ
0
Energy-dependent RNA methylation (5)
3 MIN READ
0
Energy-dependent RNA methylation (4)
5 MIN READ
0
Energy-dependent RNA methylation (3)
10 MIN READ
0
Energy-dependent RNA methylation (2)
5 MIN READ
0
Energy-dependent RNA methylation (1)
6 MIN READ
0
Secular humanism and ecoterrorism
4 MIN READ
0
Thermotolerance and longevity (2)
3 MIN READ
0
War Games: False Flag Terrorism (2)
4 MIN READ
0
War Games: False Flag Terrorism
5 MIN READ
0
Virus-driven energy theft: definition?
5 MIN READ
0
Energy-dependent biodiversity (4)
4 MIN READ
0
The tipping point? 50,000 publications (4)
3 MIN READ
0
Energy-dependent biodiversity (3)
7 MIN READ
0
Energy-dependent biodiversity (2)
2 MIN READ
0
The tipping point? 50,000 publications (3)
6 MIN READ
0
The tipping point? 50, 000 publications
4 MIN READ
0
Neo-Darwinism failed in 1995
3 MIN READ
0
Countdown to Genetics and Genomics
< 1 MIN READ
0
Magic, Miracle, or Molecular Mechanism (2)
8 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (5)
6 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
Wasted Templeton Funding (4)
3 MIN READ
0
MicroRNAs and/or QTLs: Who buried what?
2 MIN READ
0
RNA splicing, genetic variation, and disease
2 MIN READ
0
Wasted Templeton Funding (3)
2 MIN READ
0
Wasted Templeton Funding (2)
2 MIN READ
0
Millions of water molecules vs years of evolution
2 MIN READ
0
From nothing to life and death everywhere
5 MIN READ
0
Magic, Miracle, or Molecular Mechanism?
10 MIN READ
0
Molecular Diagnostics: What is unprotected life (4)
2 MIN READ
0
Molecular Diagnostics: What is unprotected life (3)
5 MIN READ
0
Molecular Diagnostics: What is unprotected life? (2)
7 MIN READ
0
Molecular Diagnostics: What is unprotected life?
2 MIN READ
0
Virus-driven sex differences?
2 MIN READ
0
Ricki Lewis’ Time Machine (4)
8 MIN READ
0
Creating and/or programming the immune system
< 1 MIN READ
0
YEC compared to Perry Marshall’s opinions
4 MIN READ
0
Creating nutrient-dependent life with enough genes to survive
3 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Virus-driven disorder prevention and health promotion
6 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Jay R. Feierman: twenty years of antagonism
5 MIN READ
0
Energy dependent RNA-mediated immunity (6)
5 MIN READ
0
Do not miss the misrepresentations
2 MIN READ
0
Energy dependent RNA-mediated immunity (5)
4 MIN READ
0
Energy dependent RNA-mediated immunity (4)
6 MIN READ
0
Energy-dependent RNA-mediated immunity (1)
10 MIN READ
0
Science vs semantics
4 MIN READ
0
Bacteria see the light and they adapt (2)
5 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands (2)
3 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
0
Bringing RNA back to epigenetics (20 years later)
11 MIN READ
0
Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9 MIN READ
0
Bacteria see the light and they adapt
7 MIN READ
0
The Light and Darkness of “Evolution 2.0”
11 MIN READ
0
Will modern human populations adapt to the Zika virus?
5 MIN READ
0
Models of scientific literacy
3 MIN READ
0
Organic Compounds and the Miracle of Smell and Taste
7 MIN READ
0
Cancer: Evolution 2.0’s Blind Spot
13 MIN READ
0
Despicable fools?
4 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (5)
10 MIN READ
0
The radical pair mechanism of ecological speciation
3 MIN READ
0
Brain evolution?
< 1 MIN READ
0
Center stage RNA-mediated events (since 1996)
3 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
Another failed rescue attempt
5 MIN READ
0
Juvenile hormone links atoms to ecosystems
3 MIN READ
0
Stress-induced energy-dependent DNA repair
4 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Ecological genomics: teleophobes respond (too late)
10 MIN READ
0
Intelligent RNAs vs evolved genes
2 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
Amino acid substitutions, stress, and human behavior
3 MIN READ
0
Finding peace and π in the light of H bond energy (2)
8 MIN READ
0
MicroRNA-mediated RNA epigenetics
2 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Perry Marshall: too much information for atheist PZ Myers
3 MIN READ
0
Epigenetic (re)programming of behavior (2)
6 MIN READ
0
Assumptions prove ignorance (2)
5 MIN READ
0
Neo-Darwinian sink testing
2 MIN READ
0
NORAD: air defense and defense against genomic entropy
7 MIN READ
0
Life history transitions and RNA-mediated survial
2 MIN READ
0
Did Dobzhansky see the UV light of creation?
10 MIN READ
0
RNA-mediated theory killers (6) (7) (8) (9) (10)
5 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs (3)
3 MIN READ
0
Manufacturing fossil “evidence”
4 MIN READ
0
RNA-mediated theory killers (4)
9 MIN READ
0
Ecological adaptations you cannot live without
6 MIN READ
0
RNA-mediated regulatory mechanisms link microbes to humans (3)
5 MIN READ
0
RNA-mediated theory killers (2)
8 MIN READ
0
Natural cooperation and Evolution 2.0
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (4)
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (5)
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
0
Teaching the biologically uninformed
3 MIN READ
0
MicroRNAs vs Red Queen hypothesis
4 MIN READ
0
Innovative Neurotechnologies Link Sunlight to Precision Medicine
4 MIN READ
0
Sulfated steroids and RNA-mediated identity codes
< 1 MIN READ
0
RNA-mediated everything
4 MIN READ
0
Neo-Darwinism vs the neocortex
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair
2 MIN READ
0
Virally derived RNA molecules and cell types
2 MIN READ
0
Positive feedback loops and epigenetic traps
2 MIN READ
0
Stress-perturbed mitochondrial dysfunction (2)
5 MIN READ
0
Stress-perturbed mitochondrial dysfunction
4 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Neuroplasticity
4 MIN READ
0
Sensationalizing no new mechanism
2 MIN READ
0
Too complex for the Complex Biological Systems Alliance
4 MIN READ
0
More re-evolved functional structures?
2 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
Rediscovering quantum behavior
2 MIN READ
0
Conserved molecular mechanisms
< 1 MIN READ
0
Models are not theories (2)
2 MIN READ
0
MicroRNA-encoded behavior
7 MIN READ
0
Can veterans and other prisoners escape pseudoscience?
2 MIN READ
0
RNA central and RNA-mediated.com
6 MIN READ
0
Ecological speciation. Get it, theorists?
< 1 MIN READ
0
Designing, engineering, and protecting biodiversity
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Human pheromone deniers: What’s next?
5 MIN READ
0
700 million years of evolution?
5 MIN READ
0
RNA-mediated retrotransposon-mediated biodiversity
3 MIN READ
0
Mystery machine vs model (2)
2 MIN READ
0
Mystery machine vs model
2 MIN READ
0
Mystery machine vs medical intelligence
2 MIN READ
0
Epigenetic inheritance of stress-perturbed protein folding
2 MIN READ
0
Preventing genomic entropy
4 MIN READ
0
Molecule of life vs animal experiments
< 1 MIN READ
0
Cancer: forward and reverse
2 MIN READ
0
Energy and evolution: another opinion?
2 MIN READ
0
Bird watchers and RNAs in cancers
2 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Viruses come alive: Tree of life pseudoscience
6 MIN READ
0
Hijacked light energy and vertebrate pathology
4 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
The creation and activation of GPCRs
4 MIN READ
0
A 5-10K comparison of design principles to evolution
3 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
From fertilization to RNA-mediated events and back
2 MIN READ
0
Genome sequencing, cadherins, and quantum consciousness
6 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Creating genes and species
3 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
Thermotolerance and Longevity
57 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
The “great filter” is an epigenetic trap
4 MIN READ
0
Information and communication (2)
6 MIN READ
0
Eibi Nevo gets it wrong
3 MIN READ
0
Rs3827760 is Val370Ala and EDARV370A
3 MIN READ
0
From “Blood Music” to Evolution 2.0
5 MIN READ
0
Protosuns, prebiotic molecules, proteins, and people
4 MIN READ
0
Ecological speciation vs revised evolutionary syntheses
6 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
Light -induced nucleic acid-mediated gene duplication?
< 1 MIN READ
0
The stability of organized genomes
5 MIN READ
0
Viruses, amino acids, and somatic cell types (3)
9 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
Viruses, amino acids, and somatic cell types
4 MIN READ
0
RNA-mediated terms of virus-induced en-deer-ment
2 MIN READ
0
Hematopoiesis and practopoiesis
4 MIN READ
0
RNA-mediated morphological AND behavioral phenotypes
2 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Is photic-zone ribosomal diversity linked to all biodiversity?
2 MIN READ
0
Riding the wrong direction
3 MIN READ
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
MicroRNA – controlled ecological adaptations
5 MIN READ
0
Celebrating independence from ridiculous theories
3 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
Unconscious affect (revisited)
2 MIN READ
0
Amino acid substitutions are not mutations
2 MIN READ
0
What I cannot create I eliminate from discussion
3 MIN READ
0
Creating and maintaining the human virome
2 MIN READ
0
Uniquely epigenomic gene regulation
2 MIN READ
0
Living the life that randomness created? (Sarcasm alert)
3 MIN READ
0
microRNAs, glycosylation, and genomes
4 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Viruses and the human-like microbiome
3 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
Tweaking the story to fit the theory
5 MIN READ
0
Appetite for ingesting theories (raw)
< 1 MIN READ
0
I forgot. How do mutations cause evolution?
4 MIN READ
0
One amino acid substitution, genes, and brain activity
3 MIN READ
0
Batch effect vs epigenetic effects
3 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
Bee-birthed epigenetics and primate cell types
5 MIN READ
0
A lighting requirement for life
11 MIN READ
3
Vitamin B3 and DNA repair
4 MIN READ
0
Ignoring systems complexity (it’s too complicated)
3 MIN READ
0
Computing via phosphorylation and fixation
3 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Protein isoforms do not evolve
3 MIN READ
0
Tissue type variation and expression of genes
< 1 MIN READ
0
From gut bacteria to breast milk and back
5 MIN READ
0
Viruses in gut microbes
4 MIN READ
0
How to find a “holy grail” under your nose
3 MIN READ
0
Linking the origin of birds to dinosaurs
< 1 MIN READ
0
Epigenetics vs the fossil record
4 MIN READ
0
An epigenetic mark links algae, worms, and flies
2 MIN READ
0
Thermodynamics and protein folding landscapes
2 MIN READ
0
RNA-mediated cell types and precision medicine
5 MIN READ
0
DNA Methylation and organized genomes
7 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
The Darwin Code by Greg Bear
13 MIN READ
0
Nutrient-dependent RNA interference
4 MIN READ
0
A genetic variant refutes neo-Darwinism
6 MIN READ
0
The miRNA/mRNA balance: a suboptimal strategy?
2 MIN READ
0
Nutrient-dependent microRNAs control cell types
6 MIN READ
0
Life: conserved ion and amino acid transporters
3 MIN READ
0
Deeply ingrained thoughts
< 1 MIN READ
0
Methylation maintains cell type differences
3 MIN READ
0
Creating nothing but a theory
4 MIN READ
0
Viruses and ecologically adapted animals
2 MIN READ
0
2 genes in 2 species (too expensive and too insignificant)
11 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Anti-entropic solar energy
5 MIN READ
0
Correctly modeling biological energy
2 MIN READ
0
Questions about life’s diversity
21 MIN READ
0
Virus-driven origin of life
2 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
Two types of microRNA are not double agents
2 MIN READ
0
What about birds?
5 MIN READ
0
RNA directed DNA methylation and cell types
4 MIN READ
0
Implicating microRNAs in cancer
2 MIN READ
0
Reverse phosphorylation
7 MIN READ
0
RNA-mediated repurposing in microbes and adaptations in primate brains
2 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
From 3-D to epigenetically-effected 4-D genome make-up
5 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
An epigenetic trap (the prequel)
5 MIN READ
0
Imagining that data historically supports evolutionary theory
7 MIN READ
0
The anti-entropic force of "Nature"
2 MIN READ
0
Nutritional epigenetics, exercise, and immune system integrity
4 MIN READ
0
Military combat training to fight disease (2)
3 MIN READ
0
Atoms to ecosystems is not almost a molecular ecology
3 MIN READ
0
Epigenetic effects of viruses on cellular homeostasis (2)
2 MIN READ
0
Quantum physics, quantum biology, and quantum consciousness
4 MIN READ
0
Biological energy and a microbiome model of a light-driven time machine
3 MIN READ
0
The biologically-based origin of the mammalian placenta (2)
6 MIN READ
0
Quantum Superpositions: let there be light
4 MIN READ
0
Are viruses microRNAs? (2)
5 MIN READ
0
Are viruses microRNAs?
3 MIN READ
0
Sneaking up from behind (2)
3 MIN READ
0
Sneaking up from behind
4 MIN READ
0
Quantum entanglement, mass, and biomass
4 MIN READ
0
Physicists: Desperate Acts
16 MIN READ
0
An epigenetic trap (the sequel)
10 MIN READ
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Mute points: most are afraid to mention them
6 MIN READ
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All of "like kind" in the (bigger) family
6 MIN READ
1
Environment epigenetically shapes the immune system
3 MIN READ
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Beneficial microbes kill beneficial mutations
4 MIN READ
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Constrained evolution is ecological adaptation
5 MIN READ
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A single amino acid substitution differentiates cell types of E. coli
3 MIN READ
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Unconstrained evolutionary innovability
4 MIN READ
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Mutagenesis: Replacing facts with theories
5 MIN READ
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ISHE's human ethology group
2 MIN READ
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From Hydra to humans vs a Lakatosian research program
4 MIN READ
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Unified nutritional and molecular mechanisms
9 MIN READ
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The future of physics predicts no future for evolutionary theory
3 MIN READ
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Model organisms: the birds and the bees
3 MIN READ
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Chemical ecology and RNA-mediated control of DNA loops
< 1 MIN READ
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Jumping back: Science or Pseudoscience? (2)
2 MIN READ
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Jumping back: Science or Pseudoscience?
6 MIN READ
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Single-cell level assay of protein biosynthesis and degradation
2 MIN READ
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Glycine and GnRH: Am I being pedantic?
4 MIN READ
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Dual genomes: exposing the evolution industry
5 MIN READ
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Meaningful dialogue, anonymous fools and idiot minions
4 MIN READ
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RNA-mediated events and "The Theory of Everything"
4 MIN READ
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Sackler Colloquium: Effects or AFFECTS on Behavior
2 MIN READ
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Eliminating correlations from evolutionary ecology
6 MIN READ
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RNA-mediated species specificity
2 MIN READ
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Are mutations beneficial?
4 MIN READ
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The key to science: experimental evidence
5 MIN READ
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Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
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There’s a model for that!
5 MIN READ
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Biologists puzzled by evolved RNAs and decaying DNA
6 MIN READ
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More than a bag of chemicals?
2 MIN READ
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Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
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Making sense of quotes scattered across disciplines
2 MIN READ
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Intelligent viruses and cancers?
10 MIN READ
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De novo DNA methylation?
3 MIN READ
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RNA eclipses the importance of DNA to cell type differentiation
4 MIN READ
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We need pattern recognition, not proclamations
3 MIN READ
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Sexual differentiation of cell types in plants
2 MIN READ
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A model of MHC 'evolution'
2 MIN READ
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From deep time into real time: What evolutionary processes?
10 MIN READ
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In theory, or supported by experimental evidence?
5 MIN READ
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Are evolutionary theorists 'nob ends'?
5 MIN READ
2
ALPHA GENOMIX
7 MIN READ
2
No excuses: Creation and the meaning of organismal complexity
7 MIN READ
0
Nutrient-dependent gene duplication in plants (but not animals?)
4 MIN READ
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Evolutionary theorists and evolutionary theists live under rocks
< 1 MIN READ
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No understanding of biodiversity
2 MIN READ
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Understanding physical forces of ecological variation and adaptation
< 1 MIN READ
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Eliminating evolutionary theory
3 MIN READ
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Behavioral ecology: please continue to believe in our fantasies
3 MIN READ
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2014 and 2004 Nobel Prize in Medicine
3 MIN READ
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RNA-mediated events: chromosomal rearrangements and genomic rearrangements
2 MIN READ
2
RNA-mediated genetic engineering (Part 3)
< 1 MIN READ
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RNA-mediated genetic engineering (Part 2)
3 MIN READ
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RNA-mediated genetic engineering
2 MIN READ
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RNA-mediated events are not a matter of faith
2 MIN READ
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Color vision refutes the evolutionary dogma of gene duplication
4 MIN READ
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Forces of "Nature" limit dissemination of information
4 MIN READ
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Genomic surveillance ends our world of RNA-mediated ecological adaptations
2 MIN READ
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Systems biology and memory disorders
3 MIN READ
0
RNA-mediated cell type differentiation and behavior
3 MIN READ
0
Different physical locations and different molecular mechanisms of health and disease
2 MIN READ
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Metabolism, fixation, health or neurodegerative disorder
2 MIN READ
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Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
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Physics denied; pseudoscientific nonsense accepted
2 MIN READ
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Ecological variation and niche construction: 1, 2, 3
6 MIN READ
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Evolving DNA before RNA
4 MIN READ
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Stop evolutionary theorists. Kill cancers
3 MIN READ
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De novo gene Creation sans evolution of genes via mutations
4 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Miracles are not miracles to evolutionary theorists
2 MIN READ
0
Mathematical model: microRNA and epigenetic regulation
2 MIN READ
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Seemingly futile cycles are not thermodynamically futile
3 MIN READ
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“Kardashians” in science
< 1 MIN READ
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Can epigenetic inheritance occur without concurrent changes in morphology AND behavior?
3 MIN READ
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Memory of repression and memory of behavior (2)
< 1 MIN READ
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Memory of repression and memory of behavior
2 MIN READ
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Quantum physics meets Evolutionary Psychology News
2 MIN READ
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Nutrient-dependent pheromone-controlled exercise-induced physiques
< 1 MIN READ
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Watching and waiting for more retractions
2 MIN READ
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RNA-mediated species diversification from microbes to primates
3 MIN READ
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RNA-mediated events found everywhere
2 MIN READ
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RNA-mediated ecological adaptation is not evolution
2 MIN READ
0
Exploding genomes and chromosomal rearrangements via RNA-mediated events
2 MIN READ
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Behavior (2): All responses are RNA-mediated not genetically-determined
4 MIN READ
0
Behavior: The first response is RNA-mediated not genetically-determined
3 MIN READ
0
Nutrient-dependent erythropoiesis and anemia
6 MIN READ
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Evolutionary heritage or ecological adaptation? Racism versus reality
4 MIN READ
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Biophysically constrained beginnings of RNA and DNA
4 MIN READ
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Baby talk: More misrepresentations of ecological adaptations
2 MIN READ
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Comparing divergent model organisms
2 MIN READ
1
A microRNA-mediated mechanism that is epigenetically inherited
2 MIN READ
0
Epimutations: Attacking pseudoscientific dogmas
4 MIN READ
0
Order and disorder: Ecological adaptations not mutations
6 MIN READ
0
microRNAs differentiate neuronal cell types
3 MIN READ
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microRNAs and species relationships
3 MIN READ
0
Drunks and Monkeys: Pseudoscientific nonsense
2 MIN READ
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The quantum biology of consciousness
3 MIN READ
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Behavior is receptor-mediated
10 MIN READ
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Genes and Race: Human History?
2 MIN READ
0
Soft atheism: a case for Creation
< 1 MIN READ
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Nutrition, pheromones and cancer (2)
2 MIN READ
0
MiRNAs methylation and ecological adaptation sans mutations
2 MIN READ
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Not focused and self-aggrandizing
2 MIN READ
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Cell-type differentiation
2 MIN READ
0
Darwinian theories vs Darwin's facts
2 MIN READ
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96 fixed amino acid substitutions, not 96 genes
6 MIN READ
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Don't tell the Creationists
2 MIN READ
0
Targeting a cancer gene
2 MIN READ
0
Social experiences epigenetically effect gene networks
2 MIN READ
0
Pheromone-controlled thermodynamics and cancer
2 MIN READ
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Your comment is awaiting moderation
2 MIN READ
0
Nutrient-dependent pheromone-controlled stickleback evolution
2 MIN READ
0
Functional coding variants are not mutations
2 MIN READ
0
Mirror neurons and microRNA: theory vs biological facts
4 MIN READ
0
Understanding the role of mutations and evolution
4 MIN READ
0
Pheromones and cancer
4 MIN READ
0
Nutrient-dependent / pheromone-controlled social structure
2 MIN READ
0
A flawed model: no tripartate synapse in the adult brain
3 MIN READ
0
Evolved development of olfactory systems
2 MIN READ
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Epigenetics and metabolism converge with pheromone production
2 MIN READ
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Behavioral epigenetics in ecological context
2 MIN READ
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Epigenetic maintenance of transcription / neuronal migration
2 MIN READ
0
Epigenetics and evolutionary success
< 1 MIN READ
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Thinking about what we know (or not)
2 MIN READ
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Epigenetic effects underlie sexual preferences II
3 MIN READ
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One of the clearest examples of epigenetic effects
< 1 MIN READ
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Epigenetic effects underlie sexual preferences (duh, and food preferences)
2 MIN READ
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Epigenetic effects on chromatin and regulatation of gene expression (in Archaea?)
2 MIN READ
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The genetics myth meets the great pheromone myth
2 MIN READ
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Genetic Influences on Epigenetically Effected Disease
2 MIN READ
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Human Pheromones: Epigenetic Effects on Hormones and Their Affects on Behavior
3 MIN READ
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Creation vs Evolution: Expression of a newly found gene
2 MIN READ
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Epistasis: Epigenetic effects of nutrient chemicals and their metabolism to pheromones
< 1 MIN READ
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The logic of gene regulatory networks
3 MIN READ
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Creating new genes (and controlling diversity)
2 MIN READ
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Epigenetic effects of viruses on cellular homeostasis
< 1 MIN READ
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Diet epigenetically effects development of the primate brain
< 1 MIN READ
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Human pheromones determine our social behavior (REJECTED)
3 MIN READ
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Human pheromones: epigenetic effects
< 1 MIN READ
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Human pheromones: another attempt to change the concept
3 MIN READ
0
Human pheromones and the fusiform fooled you area for face recognition
3 MIN READ
0
The Missing Transgenerational Epigenetic Links
2 MIN READ
0
Society for Social Neuroscience Presentation scheduled 10/11/12
2 MIN READ
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Epigenetic effects on stochastic gene expression and evolutionary psychology
2 MIN READ
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The Ghost in Your Genes – BBC Horizon
< 1 MIN READ
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Embracing galaxy-wide, cellular, and brain complexity
2 MIN READ
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Insect to human cognition
2 MIN READ
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More complicated than 1-2-3
2 MIN READ
0
What to do with research results: Warning!
2 MIN READ
0
Mischaracterizations of adaptive evolution by psychologists and biologists
2 MIN READ
0
Human pheromones and the epigenetic effects of isolation
2 MIN READ
0
Transgenerational epigenetic inheritance of sexual orientation
2 MIN READ
0
Natural selection and the behavior of whole organisms
< 1 MIN READ
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Natural Selection and the Complexity of the Genome
2 MIN READ
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Human pheromones: an epigenetic continuum from microbes to mammals
3 MIN READ
0
Biological facts constrain proponents of random mutations theory
2 MIN READ
0
Pheromones, Reciprocity, and Prosocial Behavior
3 MIN READ
0
Is the language of God the god problem? (1530 words)
6 MIN READ
0
The Epigenetics of Drug Development and Cholesterol Levels
< 1 MIN READ
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Woefully ignorant politicians and popular science
2 MIN READ
0
Epigenetic alterations due to stress
< 1 MIN READ
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Epigenetic effects on the evolution of behavior
2 MIN READ
0
Children’s healthy diets lead to healthier IQ
< 1 MIN READ
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Transgenerational epigenetic inheritance via nutrient chemicals
1 MIN READ
0
Human pheromones and IQ via neurogenic and socio-cognitive niche construction
2 MIN READ
0
Human pheromones, nutrition, DNA, epigenetics
2 MIN READ
0
Where is the love?
3 MIN READ
0
Human Pheromones and Comparative Epigenomics
2 MIN READ
0
Smelling the difference between young and old
< 1 MIN READ
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Human pheromones and the visual appeal of other people (Part Four)
3 MIN READ
0
A thought experiment
3 MIN READ
0
Human pheromones: Olfaction, odor receptors, learning, memory, mood, brains and behavior
< 1 MIN READ
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A nutrient chemical and pheromone-dependent neurogenic niche
2 MIN READ
0
Human Pheromones: The smell of the scientific universe expanding
< 1 MIN READ
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More than speculation: adaptive evolution in species from microbes to man
2 MIN READ
0
Human Pheromones in Socioaffective Neuroscience & Psychology
2 MIN READ
0
Exercise Alters Epigenetics
2 MIN READ
0
Researchers Investigate Epigenetic Patterns In Multiple Conditions
< 1 MIN READ
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Genes not culture drive humans forward (an antithetical approach)
< 1 MIN READ
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Epigenetic ‘memory’ key to nature versus nurture
< 1 MIN READ
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Study results: Human pheromones affect women’s behavior
< 1 MIN READ
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Honeybees, food odors, and perfume
< 1 MIN READ
0
Study results: Human pheromones influence human behavior
2 MIN READ
0
Molecular biology and social science theory
2 MIN READ
0