Sudden death indel polymorphism
(click to enlarge)
An insertion/deletion polymorphism within 3’UTR of RYR2 modulates sudden unexplained death risk in Chinese populations.
…different alleles of rs10692285 could alter the local structure of RYR2 mRNA and microRNA (miRNA) binding.
See for comparison: Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant
The differences between the 370A knockin mouse phenotypes and those of loss- and gain-of-function models emphasize the advantage of a more accurate mouse model.
In this study an adaptive variant links the mouse model to a modern human population via changes in the microRNA/messenger RNA balance. The adaptive variant is referred to as rs3827760, but it is also known as 1540T/C, 370A or Val370Ala.
It is an energy-dependent single nucleotide polymorphism in the ectodysplasin A receptor EDAR gene on chromosome 2. Reporting it as the Val370Ala amino acid substitution links the energy-dependent change in the base pair to the biophysically constrained pheromone-controlled fixation of the amino acid substitution via the physiology of reproduction, which links autophagy to supercoiled DNA and all energy-dependent biodiversity in all living genera.
Simply put, the supercoiled DNA protects all organized genomes from virus-driven entropy. Supercoiled DNA is the “energy as information-dependent” source of all biodiversity. See for details:
What is life when it is not protected from virus driven entropy
Abstract:
The anti-entropic force of virucidal ultraviolet light links guanine–cytosine (G⋅C) Watson–Crick base pairing from hydrogen-atom transfer in DNA base pairs in solution to supercoiled DNA, which protects the organized genomes of all living genera from virus-driven entropy. For example, protection of DNA from permanent UV damage occurs in the context of photosynthesis and nutrient-dependent RNA-directed DNA methylation, which links RNA-mediated amino acid substitutions to DNA repair. In the context of thermodynamic cycles of protein biosynthesis and degradation, DNA repair enables the de novo creation of G protein coupled receptors (GPCRs). Olfactory receptor genes are GPCRs. The de novo creation of olfactory receptor genes links chemotaxis and phototaxis from foraging behavior to social behavior in species from microbes to humans. Foraging behavior links ecological variation to ecological adaptation in the context of this atoms to ecosystems model of biophysically constrained energy-dependent RNA-mediated protein folding chemistry. Protein folding chemistry links nutrient-dependent microRNAs from microRNA flanking sequences to energy transfer and cell type differentiation in the context of adhesion proteins, and supercoiled DNA that protects all organized genomes from virus-driven entropy.
Antagonist Peter Berean repeatedly asserts that energy is not information. He has invented the term bio-functional information in an attempt to continue linking mutations to evolution, which is what was done in: Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant.
For contrast, An insertion/deletion polymorphism within 3’UTR of RYR2 modulates sudden unexplained death risk in Chinese populations links virus-driven energy theft to the pathology via loss of function associated with the insertion/deletion (indel) polymorphism. The energy-dependent polymorphism links different alleles of rs10692285 from amino acid substitutions in viruses to sudden unexplained death risk in Chinese populations. There is no mention of the fact that the amino acid substitutions that stabilize viruses would otherwise link an energy-dependent amino acid substitution from a single base pair to cell type differentiation in the sudden death-causing cells.
That fact can be viewed in the context of my model and these two reports:
1) Structural diversity of supercoiled DNA (supercoiling)
2) Structural Dynamics and Mechanochemical Coupling in DNA Gyrase (negative supercoiling)
See also: Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants
Reported as: Past 5,000 years prolific for changes to human genome
Of 1.15 million single-nucleotide variants found among more than 15,000 protein-encoding genes, 73% in arose the past 5,000 years, the researchers report.
On average, 164,688 of the variants — roughly 14% — were potentially harmful, and of those, 86% arose in the past 5,000 years. “There’s so many of [variants] that exist that some of them have to contribute to disease,” says Akey
Once again, we see that theorists must learn the difference between an energy-dependent RNA-mediated amino acid substitution and a mutation before they can grasp the levels of complexity that must be integrated into models of biophysically constrained energy-dependent biodiversity.
The problem that most theorists have with the concept of energy as information is due to the fact that they do not know the difference between an energy-dependent amino acid substitution and a mutation, which is caused by virus-driven energy theft.
See: Virus-driven mutation or amino acid substitution
Pseudoscientists invented a theory based on de Vries definition of mutation, and more theories were added in the absence of experimental evidence that could link top-down causation to cell type differentiation in all genera. Instead of energy-dependent cell type differentiation, we got this:
For comparison, see: Mutation-Driven Evolution
Excerpt:
Mutation… includes nucleotide substitution, insertion/deletion, segmental gene duplication, genomic duplication, changes in gene regulatory systems, transposition of genes, horizontal gene transfer, etc.
My comment: The definition above links mutations to any change in any genome.
See for comparison: Updates of the HbVar database of human hemoglobin variants and thalassemia mutations
Excerpt:
Single nucleotide substitutions or indels [insertions/deletions] can lead to several hemoglobin variants owing to amino acid replacements, while molecular defects [mutations] in either regulatory or coding regions of the human HBA2, HBA1, HBB or HBD genes can minimally or drastically reduce their expression, leading to α-, β- or δ-thalassemia, respectively.
My comment: The facts about nutrient energy-dependent amino acid substitutions link hemoglobin variants from ecological adaptation to healthy longevity and the facts also link molecular defects from mutations to the pathology of α-, β- or δ-thalassemia, respectively. It would be difficult to include facts about biophysically constrained energy dependent cell type differentiation in the context of any other model that links amino acid substitutions to healthy longevity and links mutations to all pathology in all living genera.
Unfortunately, some medical laboratory scientists are still not getting the message about the difference between a mutation and fixation of an amino acid substitution.
See also the attacks on my credibility and my model in this discussion attempt, which drew participation and more antagonism from the group’s administrators, John L. Leonard and Peter Berean.
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5 MIN READ
0
Mouse morphs and primate diversity in 50 years
7 MIN READ
0
Two retractions of human idiocy
2 MIN READ
0
Exposing the 2nd Law to more ridicule (1)
6 MIN READ
0
Vulgar Antagonists vs Quantum Effects
3 MIN READ
0
Reporting new scientific truths is not allowed in the USA
3 MIN READ
0
Who created your virus-driven death gene? (1)
5 MIN READ
0
Light-activated error free DNA repair (2)
8 MIN READ
0
MicroRNAs and the Cassandra syndrome (revisited)
4 MIN READ
0
Achromobacter and killer theories
2 MIN READ
0
Eutrophication and phosphorylated biodiversity
6 MIN READ
0
Eating electrons and excreting degraded energy
3 MIN READ
0
Pheromones biophysically constrain RNA-mediated biodiversity (1)
5 MIN READ
0
Pheromones biophysically constrain base editing and RNA editing
3 MIN READ
0
From base editing to RNA editing (5)
< 1 MIN READ
0
The next reformation: 500 years too late? (1)
< 1 MIN READ
0
The next reformation: 500 years too late? (2)
2 MIN READ
0
From base editing to RNA editing
2 MIN READ
0
Cryo-EM: More than a suggestion
< 1 MIN READ
0
Long-term adaptation replaces evolution (3)
6 MIN READ
0
Long-term adaptation replaces evolution (2)
2 MIN READ
0
Exome Sequencing Impact in Routine Care
4 MIN READ
0
Losers: Rediscovering an epigenetic key (2)
8 MIN READ
0
Losers: rediscovering an epigenetic key
2 MIN READ
0
Virulence: Out of stock
2 MIN READ
0
Faith in evolution: Paleontology as a molecular science
5 MIN READ
0
Energy-dependent structure and function: Until death (5)
4 MIN READ
0
Energy-dependent structure and function: Until death (3)
3 MIN READ
0
Energy-dependent structure and function: Until death (2)
5 MIN READ
0
Energy-dependent structure and function: Until death (1)
4 MIN READ
0
Until death: Virus-driven failure of multisensory integration (2)
6 MIN READ
0
Biophysically constrained intelligence vs human idiocy
4 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (7)
4 MIN READ
0
Entertaining yourself to death
6 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (6)
5 MIN READ
0
Criticisms of a validated model
9 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (5)
2 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (4)
4 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (3)
2 MIN READ
0
Predicting who wins the 2017 Nobel Prizes
4 MIN READ
0
Caught in an epigenetic trap: flag waving consequences
< 1 MIN READ
0
Dispelling the ignorance of theorists
4 MIN READ
0
Sci-Hub vs limits on the dissemination of information
6 MIN READ
0
Inventing “Transcriptome Trajectory Turning Points”
2 MIN READ
0
Optogenetics replaces fMRI but not pseudoscientific nonsense
2 MIN READ
0
Science vs Secularism: Molecular Mechanisms or Math?
6 MIN READ
0
Methylation and the Innate Immune System
< 1 MIN READ
0
Sexual communication signals: New Insights!
10 MIN READ
0
Quantum physics, Patrick Bateson, and neo-Darwinian nonsense
3 MIN READ
0
Host-derived creation of all pathology (2 of 2)
9 MIN READ
0
God vs host-derived creation of virus-driven pathology (2)
4 MIN READ
0
God vs host-derived creation of virus-driven pathology
6 MIN READ
0
Stem cells do not create themselves
3 MIN READ
0
Pseudoscientists hate what science explains! (3)
4 MIN READ
0
Your indifference is killing you and others
5 MIN READ
0
Your indifference is killing you and others (3)
4 MIN READ
0
Your indifference is killing you and others (4)
4 MIN READ
0
Robert Sapolsky’s legacy of atheistic pseudoscientific nonsense
4 MIN READ
0
Automagical protein creation sans energy
9 MIN READ
0
Solar analemma with a total solar eclipse
2 MIN READ
0
The Origin of Information (4)
4 MIN READ
0
Can protein folding chemistry be understood by theorists?
5 MIN READ
0
Evolutionary congruence (losers) vs ecological adaptation (winners)
3 MIN READ
0
Pattern recognition vs evolutionary processes (revisited)
7 MIN READ
0
Energy-dependent physical and biophysical constraints (10)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (9)
3 MIN READ
0
Energy-dependent physical and biophysical constraints (8)
5 MIN READ
0
Energy-dependent physical and biophysical constraints (6)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (5)
7 MIN READ
0
Energy-dependent physical and biophysical constraints (4)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (3)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (2)
4 MIN READ
0
Energy-dependent physical and biophysical constraints (1)
5 MIN READ
0
Cell type assembly and the space-time continuum
2 MIN READ
0
Richard P. Feynman refuted theistic evolution
5 MIN READ
0
Epigenetic effects of stress by Bruce McEwen (2)
3 MIN READ
0
The emergence of light as energy from a life-giving star (2)
2 MIN READ
0
The emergence of light as energy from a life-giving star
11 MIN READ
2
God’s shrinking role in salvation (3)
9 MIN READ
0
God's shrinking role in salvation (3)
9 MIN READ
0
MicroRNAs GnRH and the failure of sex research
7 MIN READ
0
God’s shrinking role in salvation (2)
5 MIN READ
0
Food energy-dependent cell type differentiation (2)
10 MIN READ
0
Hard Science vs the neo-Darwinian “magic box”
9 MIN READ
0
Infections and age change the odor of wine and people
4 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models (4)
2 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models
7 MIN READ
0
Food energy-dependent epigenetic adaptation (3)
3 MIN READ
0
Food energy-dependent epigenetic adaptation (2)
< 1 MIN READ
0
Food energy-dependent epigenetic adaptation
11 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (6)
8 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (5)
4 MIN READ
0
Cytosis in the light of evolution
5 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (4)
2 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (3)
5 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability
8 MIN READ
0
UV light and non-coding RNA
2 MIN READ
0
Nothing evolved into all biodiversity on Earth
4 MIN READ
0
Energy as information and constrained endogenous RNA interference (4)
7 MIN READ
0
What energy source do proteins prefer?
6 MIN READ
0
Energy-dependent microRNA biogenesis
4 MIN READ
0
Draining the academic swamp of parasites
3 MIN READ
0
The death of human ethology via ecology
7 MIN READ
0
Ignoring peer review, ATP, and microRNA biosynthesis
5 MIN READ
0
Food and pheromone-constrained healthy longevity
2 MIN READ
0
The death of CRISPR; long live endogenous RNAi
5 MIN READ
0
Dispensing with all pseudoscientific nonsense about evolution (1)
5 MIN READ
0
Virus-driven downsizing of the human brain (4)
2 MIN READ
0
Feng Zhang refutes theistic evolution
4 MIN READ
0
Open Science: Closed to facts about microRNAs
6 MIN READ
0
Viruses in pathogenic variants disrupt alternative splicings (2)
3 MIN READ
0
Viruses in pathogenic variants disrupt alternative splicings
2 MIN READ
0
Respiration-dependent endogenous RNA interference
4 MIN READ
0
Epigenetically-effected nucleosome repositioning sheds Dobzhansky’s light on evolution
3 MIN READ
0
Synthetic RNA-based switches
2 MIN READ
0
Sunlight bursts the social bubble of physics and math
3 MIN READ
0
Functionally interdependent editing and methylation
4 MIN READ
0
Cytosis: Biology Content
7 MIN READ
0
Light-activated feedback loops vs self-organization of ecosystems
7 MIN READ
0
Harvard researchers support young earth creationism
< 1 MIN READ
0
Cytosis: A Cell Biology Board Game
< 1 MIN READ
0
Sal Giardina: apologetics revisited
8 MIN READ
0
Life in your UV light-constrained galaxy
5 MIN READ
0
Who will kill the billion dollar baby? Bill Gates or Donald Trump
3 MIN READ
0
Food for thought: Penrose v Ellis (3)
4 MIN READ
0
Thinking about energy is not radical re-thinking
6 MIN READ
0
Food for thought: Penrose v Ellis (1)
5 MIN READ
0
Magnussen’s “Faith fools” keep the faith
3 MIN READ
0
Energy-dependent pheromone-controlled entropy (3)
2 MIN READ
0
Energy-dependent pheromone-controlled entropy (4)
3 MIN READ
0
Proof: Sunlight is energy as information
< 1 MIN READ
0
Energy-dependent pheromone-controlled entropy (2)
6 MIN READ
0
Sunlight: the essence of precision medicine and world peace
6 MIN READ
0
The essence of precision medicine: drug targets or healthy longevity?
4 MIN READ
0
The essence of precision medicine
4 MIN READ
0
Ab initio cell wall invention, emergence, and evolution (2)
8 MIN READ
0
Allen Institute confirms food energy is information
6 MIN READ
0
RNA-mediated adult learning, memory, and neurogenesis
3 MIN READ
0
Energy-dependent allelic imbalances, viruses, and pathology
3 MIN READ
0
Ab initio cell wall invention, emergence, and evolution (1)
2 MIN READ
0
Biologically uninformed biologists fight back and lose
3 MIN READ
0
Theistic evolutionists fight back and lose (3)
4 MIN READ
0
Theistic evolutionists fight back and lose (2)
4 MIN READ
0
Theistic evolutionists fight back and lose
4 MIN READ
0
Young earth creationists refute theistic evolution
3 MIN READ
0
Charles Darwin refutes theistic evolution
2 MIN READ
0
Bill Gates refutes theistic evolution (prequel)
2 MIN READ
0
Bill Gates refutes theistic evolution (sequel)
8 MIN READ
0
Bill Gates refutes theistic evolution
4 MIN READ
0
Emily Witkin refutes theistic evolution
2 MIN READ
0
Wikipedia refutes theistic evolution
4 MIN READ
0
RNA editing refutes theistic evolution
4 MIN READ
0
Serious scientists refute theistic evolution again
3 MIN READ
0
Pseudoscientists fail to refute theistic evolution
4 MIN READ
0
Stuart Kauffman refutes theistic evolution
3 MIN READ
0
May the anti-entropic force of sunlight be with you
4 MIN READ
0
Francis S. Collins refutes theistic evolution
6 MIN READ
0
Energy is information. Objections over ruled. You’re fired!
7 MIN READ
0
Happy Darwin Day (2017)
4 MIN READ
0
George Church refutes theistic evolution (3)
5 MIN READ
0
George Church refutes theistic evolution (2)
2 MIN READ
0
George Church refutes theistic evolution
5 MIN READ
0
Natural selection for codon optimality and quantum viruses
5 MIN READ
0
Physicists: Desperate Acts (revisited)
6 MIN READ
0
Energy as information and constrained endogenous RNA interference (3)
4 MIN READ
0
Virus-driven energy theft and premature death
3 MIN READ
0
Fighting for virus-driven pathology
5 MIN READ
0
ATP-dependent creation of RNA
2 MIN READ
0
Dobzhansky 1973 and precision medicine (5)
3 MIN READ
0
Atomic theory vs facts about hydrogen-atom transfer
4 MIN READ
0
Dobzhansky 1973 and Precision Medicine (2)
5 MIN READ
0
Trump’s appeal to common sense (2)
3 MIN READ
0
Science journalists or paid propagandists? (4)
6 MIN READ
0
Another failed attempt to address the malaria challenge
2 MIN READ
0
Dobzhansky 1973 and precision medicine
6 MIN READ
0
Twisted theories and weaponized facts
3 MIN READ
0
Autophagy: from pre-mRNAs to microRNAs, enhancers, QTLs et al.
6 MIN READ
0
Chirality, nutritional epigenetics, autophagy, and ethnicity
< 1 MIN READ
0
Mutations: the “driving force” behind human brain complexity?
6 MIN READ
0
Mutations: the "driving force" behind human brain complexity?
6 MIN READ
0
Science journalists or paid propagandists? (3)
6 MIN READ
0
Critical values expose virus-driven energy theft (2)
4 MIN READ
0
Theorists sell hidden energy (2)
4 MIN READ
0
Critical values expose virus-driven energy theft
6 MIN READ
0
Theorists sell hidden energy
3 MIN READ
0
Anti-entropic energy and the “Music of Life”
3 MIN READ
0
Anti-entropic energy and the "Music of Life"
3 MIN READ
0
Evolved patterns of brain stimulation
3 MIN READ
0
Chirality is reality
6 MIN READ
0
Energy-dependent hydrogen bonds in supercoiled DNA
7 MIN READ
0
Energy-dependent chirality
6 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5 MIN READ
0
Vietnam Veterans and others with glioblastoma
3 MIN READ
0
Energy-dependent sensory maps (1996-2016)
5 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016
12 MIN READ
0
Energy-dependent oscillating gene networks organize life
4 MIN READ
0
2016 obfuscated facts about energy as information
5 MIN READ
0
More refutations of neo-Darwinian nonsense
7 MIN READ
0
Dietary lutein and pheromone-controlled brain development
4 MIN READ
0
Re-inventing mutation-driven evolution (2)
4 MIN READ
0
Re-inventing mutation-driven evolution
3 MIN READ
0
Anti-entropic virucidal energy as information
10 MIN READ
0
Bio-functional information
3 MIN READ
0
Bird-brained theorists
< 1 MIN READ
0
Expunging the distinguished public
2 MIN READ
0
Explorers who do not know what is known (2)
6 MIN READ
0
Explorers who do not know what is known
4 MIN READ
0
Autophagy is the antiphage defense strategy
3 MIN READ
0
Energy-dependent de novo creation and neurogenesis (2)
5 MIN READ
0
Energy-dependent de novo creation and neurogenesis
7 MIN READ
0
Theories vs facts about polycombic adaptation
3 MIN READ
0
Tasting light links energy from creation to adaptation
9 MIN READ
0
Politicized science: The demise of RNA-mediated.com?
3 MIN READ
0
Combating evolution: Battlefield medicine vs politicized science
6 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Metabolic Phenotyping Research
2 MIN READ
0
Phylogenetic similarity sans energy
2 MIN READ
0
Happy biophysically constrained Thanksgiving (in the USA)
3 MIN READ
0
De novo gene creation: Ignoring the experimental evidence
7 MIN READ
0
Energy-dependent coulombic, autophagic, polycombic healthy longevity
4 MIN READ
0
Light, behavior and autophagy, a gender-specific risk factor
4 MIN READ
0
Controlled amino acid treatment of all pathology
4 MIN READ
0
Energy-dependent purifying selection / autophagy (2)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (3)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (4)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (5)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (6)
3 MIN READ
0
Energy-dependent purifying selection / autophagy
2 MIN READ
0
Optogenetics: Let there be virucidal light!
2 MIN READ
0
Theorists struggle with the concept of autophagy
2 MIN READ
0
Base pairs, amino acids and phenotypes
10 MIN READ
0
Survivors of RNA-mediated terrorism
5 MIN READ
0
Building delicious base pairs in class. It’s elementary Watson and Crick
3 MIN READ
0
Building delicious base pairs in class. It's elementary Watson and Crick
3 MIN READ
0
RNA-mediated “repurposing” is autophagy
2 MIN READ
0
RNA-mediated "repurposing" is autophagy
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (8)
4 MIN READ
0
Energy-dependent maternal-to-zygotic transition
6 MIN READ
1
Virus-driven mutation or amino acid substitution
5 MIN READ
0
Epigenetically effected energy-dependent fluorescence (2)
6 MIN READ
0
Epigenetically effected energy-dependent fluorescence
5 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (7)
3 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (5)
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (4)
< 1 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (3)
< 1 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (2)
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution
< 1 MIN READ
0
From precis to pre-mRNA and proof of concept in F1, F2, F3
6 MIN READ
0
From Precis to Proof in 6000 years (2)
5 MIN READ
0
From Precis to Proof in 6000 years
9 MIN READ
0
Coulombic interactions facilitate polycombic adaptation
5 MIN READ
0
Top-down adaptation vs bottom-up evolution
6 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (3)
< 1 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (2)
3 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
Polycombic ecological adaptation as a science, not a theory
3 MIN READ
0
Attacking Young Earth Creationists
5 MIN READ
0
Olfactory receptor pseudo-pseudogenes
2 MIN READ
0
80 years of causal analysis (1936 – 2016)
11 MIN READ
0
Energy-dependent polycombic ecological adaptation
21 MIN READ
0
Did evolution autophosphorylate your kinases? (3)
2 MIN READ
1
Predictable idiosyncratic evolved convergence
3 MIN READ
0
The human virome (revisited)
4 MIN READ
0
Carl Woese was wrong
2 MIN READ
0
The natural success of RNAi and failed treatment
7 MIN READ
0
Pheromone-controlled autophagy
4 MIN READ
0
Virus-mediated hecatombic evolution
2 MIN READ
0
Hecatombic evolution via oncocers and oncohistones
9 MIN READ
0
Did evolution autophosphorylate your kinases?
5 MIN READ
1
Nutrient-dependent autophagy
3 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy (2)
6 MIN READ
0
The last RNA-mediated theory killer (2)
7 MIN READ
0
Asking the right questions (2)
3 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy
3 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
Hypothesis free pseudoscience vs facts (5)
6 MIN READ
0
Hypothesis free pseudoscience vs facts (4)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (1)
5 MIN READ
0
The last RNA-mediated theory killer
< 1 MIN READ
0
Base pairs, olfaction and RNA thermometers
4 MIN READ
0
Chromatin: The structure of DNA (2)
8 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Consciousness is simply food rearranged
2 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
A working model of “captured” genes
6 MIN READ
0
DNA repair via junk DNA (2)
5 MIN READ
0
The Aquatic Ape / Waterside Ape divergence
6 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
Displays of ecological adaptation (2)
3 MIN READ
0
DNA repair via junk DNA (1)
5 MIN READ
0
Displays of ecological adaptation
2 MIN READ
0
Virus-driven energy theft causes cancer
2 MIN READ
0
Linking RNA structure to function
3 MIN READ
0
Exosomes, Inflammatory Disease, Pathogenesis, Treatment
< 1 MIN READ
0
How did the innate immune system evolve?
4 MIN READ
0
The Aquatic Ape: New evidence?
4 MIN READ
0
Plant microRNAs slow virus-driven aging
3 MIN READ
0
Increased soil pH and nutrient availability
4 MIN READ
0
Energy-dependent cellular communication
3 MIN READ
0
Lawless evolution: No physics
4 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Virus-driven energy theft: honeybee model
3 MIN READ
0
Antithetical conclusions (7)
3 MIN READ
0
Antithetical conclusions (5)
4 MIN READ
0
Anthetical conclusions (2)
5 MIN READ
0
Anthetical conclusions
3 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
RNAi: From magic bullet to billion dollar baby
4 MIN READ
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
Pseudoscientists ignore what serious scientists prove
6 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
Virus-driven downsizing of the human brain (3)
4 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
The end of neo-Darwinism
5 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity
4 MIN READ
0
The Origin of Information (2)
6 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution
6 MIN READ
0
Funding the Human Genome Project-Write
2 MIN READ
0
RNA-mediated programming of E.coli
< 1 MIN READ
0
Virus-driven downsizing of the human brain (2)
< 1 MIN READ
0
Virus-driven downsizing of the human brain
2 MIN READ
0
MicroRNAs and sexual orientation
8 MIN READ
0
Innate immunity and multiplexing
7 MIN READ
0
Amino acids and virus penetration
3 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
RNA methylation
2 MIN READ
0
Masters of deception about nature (2)
7 MIN READ
0
Masters of deception about nature
8 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
Cracking the Olfactory Code?
5 MIN READ
0
RNA methylation, behavior, and disease
6 MIN READ
0
Energy-dependent RNA methylation (10)
4 MIN READ
0
Energy-dependent RNA methylation (8)
4 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (5)
3 MIN READ
0
Energy-dependent RNA methylation (3)
10 MIN READ
0
Energy-dependent RNA methylation (2)
5 MIN READ
0
Energy-dependent RNA methylation (1)
6 MIN READ
0
Secular humanism and ecoterrorism
4 MIN READ
0
War Games: False Flag Terrorism
5 MIN READ
0
Energy-dependent biodiversity (4)
4 MIN READ
0
Energy-dependent biodiversity (3)
7 MIN READ
0
Energy-dependent biodiversity (2)
2 MIN READ
0
Energy-dependent biodiversity
5 MIN READ
0
The tipping point? 50,000 publications (3)
6 MIN READ
0
Neo-Darwinism failed in 1995
3 MIN READ
0
Countdown to Genetics and Genomics
< 1 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (2)
7 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
Wasted Templeton Funding (4)
3 MIN READ
0
RNA splicing, genetic variation, and disease
2 MIN READ
0
Wasted Templeton Funding (3)
2 MIN READ
0
Wasted Templeton Funding (2)
2 MIN READ
0
Millions of water molecules vs years of evolution
2 MIN READ
0
A bumper crop of virus-infected weeds and people
2 MIN READ
0
Molecular Diagnostics: What is unprotected life (4)
2 MIN READ
0
Molecular Diagnostics: What is unprotected life (3)
5 MIN READ
0
Molecular Microbial Ecology
8 MIN READ
0
Molecular Diagnostics: What is unprotected life? (2)
7 MIN READ
0
Molecular Diagnostics: What is unprotected life?
2 MIN READ
0
Ricki Lewis’ Time Machine (4)
8 MIN READ
0
Creating and/or programming the immune system
< 1 MIN READ
0
Half truths support theories without facts
4 MIN READ
0
YEC compared to Perry Marshall’s opinions
4 MIN READ
0
Ricki Lewis’ Time Machine (3)
5 MIN READ
0
Creating nutrient-dependent life with enough genes to survive
3 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Virus-driven disorder prevention and health promotion
6 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Jay R. Feierman: twenty years of antagonism
5 MIN READ
0
Do not miss the misrepresentations
2 MIN READ
0
Energy dependent RNA-mediated immunity (3)
8 MIN READ
0
RNA-mediated DNA modifications
5 MIN READ
0
Science vs semantics
4 MIN READ
0
From angstroms to ecosystems and entropy
2 MIN READ
0
Bacteria see the light and they adapt (2)
5 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
0
Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA
2 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (7)
5 MIN READ
0
The Light and Darkness of “Evolution 2.0”
11 MIN READ
0
Organic Compounds and the Miracle of Smell and Taste
7 MIN READ
0
Neuroscience Virtual Event vs AAAS Symposium
3 MIN READ
0
Cancer: Evolution 2.0’s Blind Spot
13 MIN READ
0
Ricki Lewis’ Time Machine (2)
6 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Virus-perturbed alternative splicings
3 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (5)
10 MIN READ
0
The radical pair mechanism of ecological speciation
3 MIN READ
0
Center stage RNA-mediated events (since 1996)
3 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
Stress-induced energy-dependent DNA repair
4 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Ecological genomics: teleophobes respond (too late)
10 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
Amino acid substitutions, stress, and human behavior
3 MIN READ
0
MicroRNA-mediated RNA epigenetics
2 MIN READ
0
RNA methylation, RNA-directed DNA methylation, learning and memory
3 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Assumptions prove ignorance (2)
5 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
Assumptions prove ignorance
5 MIN READ
0
Neo-Darwinian sink testing
2 MIN READ
0
NORAD: air defense and defense against genomic entropy
7 MIN READ
0
Life history transitions and RNA-mediated survial
2 MIN READ
0
Did Dobzhansky see the UV light of creation?
10 MIN READ
0
Researchers rename, reshuffle, and reveal their ignorance
3 MIN READ
0
RNA-mediated theory killers (6) (7) (8) (9) (10)
5 MIN READ
0
Manufacturing fossil “evidence”
4 MIN READ
0
RNA-mediated theory killers (4)
9 MIN READ
0
RNA-mediated theory killers (5)
2 MIN READ
0
RNA-mediated theory killers (3)
7 MIN READ
0
RNA-mediated theory killers (2)
8 MIN READ
0
RNA-mediated theory killers
6 MIN READ
0
Natural cooperation and Evolution 2.0
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (4)
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
0
Sulfated steroids and RNA-mediated identity codes
< 1 MIN READ
0
RNA-mediated everything
4 MIN READ
0
Neo-Darwinism vs the neocortex
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair
2 MIN READ
0
Nutrient-dependent trophic analogs
3 MIN READ
0
Organization of biological sequences
2 MIN READ
0
Virally derived RNA molecules and cell types
2 MIN READ
0
Positive feedback loops and epigenetic traps
2 MIN READ
0
Stress-perturbed mitochondrial dysfunction (2)
5 MIN READ
0
Behavioral Immune System model
4 MIN READ
0
Stress-perturbed mitochondrial dysfunction
4 MIN READ
0
Understanding cell type differentiation
3 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Neuroplasticity
4 MIN READ
0
Sensationalizing no new mechanism
2 MIN READ
0
Too complex for the Complex Biological Systems Alliance
4 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
Virus, transposon and plasmid evolution
< 1 MIN READ
0
Models are not theories (2)
2 MIN READ
0
Models are not theories (1)
2 MIN READ
0
Can veterans and other prisoners escape pseudoscience?
2 MIN READ
0
Unraveling the secrets of RNA-mediated events
2 MIN READ
0
RNA central and RNA-mediated.com
6 MIN READ
0
Ecological speciation. Get it, theorists?
< 1 MIN READ
0
Designing, engineering, and protecting biodiversity
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Controled Stem Cell Expansion
3 MIN READ
0
Neo-Darwinian logic is nonsense
3 MIN READ
0
FREE* SAMPLE: Histone modification
4 MIN READ
0
700 million years of evolution?
5 MIN READ
0
Biophysically constrained or unconstrained?
2 MIN READ
0
Mutated mitochondrial genes vs Supercoiled DNA
2 MIN READ
0
RNA-mediated retrotransposon-mediated biodiversity
3 MIN READ
0
Mystery machine vs model (2)
2 MIN READ
0
Mystery machine vs medical intelligence
2 MIN READ
0
Preventing genomic entropy
4 MIN READ
0
Molecule of life vs animal experiments
< 1 MIN READ
0
Energy and evolution: another opinion?
2 MIN READ
0
Keep the gay gene theory?
< 1 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Exosomes and the RNA-mediated future of medicine (2)
< 1 MIN READ
0
Multi-omic analysis features (SNPs, miRNA)
3 MIN READ
0
Phytochemical link from the sun to cell types
2 MIN READ
0
Genome sequencing, cadherins, and quantum consciousness
6 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
A “new” code enables ecological adaptation
4 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
The “great filter” is an epigenetic trap
4 MIN READ
0
Rs3827760 is Val370Ala and EDARV370A
3 MIN READ
0
From “Blood Music” to Evolution 2.0
5 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
Epimutation.com: a domain of confusion
8 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Picornaviruses moving between primates (or not)
2 MIN READ
0
Riding the wrong direction
3 MIN READ
0
Decreased phenotypic variation: Faith in Facts
7 MIN READ
1
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
Becoming biologically informed (2)
3 MIN READ
0
Is SUMOylation RNA-directed DNA methylation? (revisited)
4 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
The sum of our RNA-mediated parts
2 MIN READ
0
Amino acid substitutions are not mutations
2 MIN READ
0
RNA-mediated development (2)
< 1 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Physicians who practice evolutionary medicine?
3 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Viruses and the human-like microbiome
3 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
One amino acid substitution, genes, and brain activity
3 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
Missing a fact: microRNAs are genomic biomarkers
4 MIN READ
1
Ignoring systems complexity (it’s too complicated)
3 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
The microbiome, pharmacogenetics, and privacy
< 1 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Tissue type variation and expression of genes
< 1 MIN READ
0
From gut bacteria to breast milk and back
5 MIN READ
0
MicroRNAs and the exposome (2)
< 1 MIN READ
0
Effect and affect of a single base-pair change
4 MIN READ
0
RNA-mediated silencing of a chromosome
3 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
Amino acid-dependent cell type differentiation
8 MIN READ
0
A genetic variant refutes neo-Darwinism
6 MIN READ
0
Silencing genes and serious scientists
3 MIN READ
0
The miRNA/mRNA balance: a suboptimal strategy?
2 MIN READ
0
Nutrient-dependent microRNAs control cell types
6 MIN READ
0
MicroRNAs and memory
< 1 MIN READ
0
Graphic misrepresentations of ecological adaptation
2 MIN READ
0
Too many targets for theories
3 MIN READ
0
Creating nothing but a theory (2)
4 MIN READ
0
Creating nothing but a theory
4 MIN READ
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Mimicking claims and ignoring facts
4 MIN READ
0
Correctly modeling ecological adaptation
4 MIN READ
0
Questions about life’s diversity
21 MIN READ
0
Virus-driven origin of life
2 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
Walk towards the light
< 1 MIN READ
0
Two types of microRNA are not double agents
2 MIN READ
0
Epigenetics Skeptism
5 MIN READ
0
Is DNA-directed transcription RNA-mediated?
2 MIN READ
0
What about birds?
5 MIN READ
0
Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs
2 MIN READ
0
Reverse phosphorylation
7 MIN READ
0
RNA-mediated repurposing in microbes and adaptations in primate brains
2 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
From 3-D to epigenetically-effected 4-D genome make-up
5 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
Atheism: Arrogant, useless, and divisive ignorance
7 MIN READ
0
Military combat training to fight disease (2)
3 MIN READ
0
RNA-mediated epigenetic modification via DNA-methylation
4 MIN READ
0
Are viruses microRNAs? (2)
5 MIN READ
0
Sneaking up from behind
4 MIN READ
0
All of “like kind” (Part 2)
2 MIN READ
0
Environment epigenetically shapes the immune system
3 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
Jumping back: Science or Pseudoscience? (2)
2 MIN READ
0
Single-cell level assay of protein biosynthesis and degradation
2 MIN READ
0
Biologists puzzled by evolved RNAs and decaying DNA
6 MIN READ
0
SNPs and millions of small variations in the human genome
3 MIN READ
0
More than a bag of chemicals?
2 MIN READ
0
Achiral GnRH: no prophesy, just prediction
9 MIN READ
0
Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
0
RNA eclipses the importance of DNA to cell type differentiation
4 MIN READ
0
RNA-mediated genetic engineering (Part 2)
3 MIN READ
0
RNA-mediated genetic engineering
2 MIN READ
0
Genomic surveillance ends our world of RNA-mediated ecological adaptations
2 MIN READ
0
RNA-mediated cell type differentiation and behavior
3 MIN READ
0
Metabolism, fixation, health or neurodegerative disorder
2 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Physics denied; pseudoscientific nonsense accepted
2 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Quantum physics meets Evolutionary Psychology News
2 MIN READ
0
RNA-mediated events found everywhere
2 MIN READ
0
Some neuroscientists think a mutation led to human language development
< 1 MIN READ
0
Behavior (3): All responses are RNA-mediated in bees
3 MIN READ
0
Behavior: The first response is RNA-mediated not genetically-determined
3 MIN READ
0
Biophysically constrained beginnings of RNA and DNA
4 MIN READ
0
A microRNA-mediated mechanism that is epigenetically inherited
2 MIN READ
0
Order and disorder: Ecological adaptations not mutations
6 MIN READ
0
microRNAs differentiate neuronal cell types
3 MIN READ
0
microRNAs and species relationships
3 MIN READ
0
Drunks and Monkeys: Pseudoscientific nonsense
2 MIN READ
0
Another powerful refutation of mutation-initiated natural selection
4 MIN READ
0
The new light of chromosomal rearrangements
3 MIN READ
0
Chromosomal rearrangements and ecological adaptations
4 MIN READ
0
96 fixed amino acid substitutions, not 96 genes
6 MIN READ
0
Pheromone-controlled thermodynamics and cancer
2 MIN READ
0
Seeds of life: astrobiological theory and mutations theory
3 MIN READ
0
Alzheimer's, microRNAs, and olfaction
< 1 MIN READ
0
Constraints on mutational drift
< 1 MIN READ
0
Epigenetic effects underlie sexual preferences IV
< 1 MIN READ
0
The hormone-miRNA axis, life span, and sexual orientation
3 MIN READ
0
MicroRNA binds messenger RNA: Adaptive Evolution
< 1 MIN READ
0
Disorders of development: altered microRNA / messenger RNA balance
< 1 MIN READ
0
Evolution at work sans random mutations
2 MIN READ
0
Sex differences in Alzheimer's and everything else
2 MIN READ
0
