Sunlight: the essence of precision medicine and world peace

By: James V. Kohl | Published on: March 10, 2017

See for review: The essence of precision medicine
See for comparison:
We not only reject Trump’s values and policies, we also renew our commitment to a future where both the church and the academy will foster attitudes and actions so that human beings and the whole of creation can thrive. We join our hearts, our minds, our voices, and our actions with those of religious believers–Christians, Jews, Muslims, and
people of all faiths, as well as with secular people of good conscience, to resist the present destructive politics in our country and to seek reversal of their destructive consequences here and around the world.

This is unadulterated nonsense. Trump’s policies are clearly designed to protect us from the media-industrial complex that pervades the ivory towers of all pseudoscientists.

The “complex” has metaphorically choked the life out of millions of people who have needlessly suffered and prematurely died from virus-driven energy theft.

Anyone who signs this could potentially be convicted of sedition. Sorry if this warning is too late for those who may be the first to pay for their sins of ignorance.

See also: Viruses can Stimulate Photosynthesis in Bacteria  The ignorance overwhelms every discipline as it is included in everything that links the anti-entropic virucidal energy of sunlight to cell type differentiation and healthy longevity in all genera. Photosynthesis protects supercoiled DNA from virus-driven energy theft, and they report that fact as if viruses created the sun.

See also: L-form bacteria, cell walls and the origins of life

There is no mention of the energy-dependent origins of life and no mention of endogenous RNA interference, but they link

1) Invention of cell wall
2) Emergence of Archaea
3) Evolutionary development

That’s the magic of evolutionary development. First the cell wall is invented and then species emerge so that their emergence can be linked to their evolutionary develoment. For comparison, the works of all serious scientists link the virus-driven hecatombic evolution of all pathology to the destruction of the cell wall, which obviously was created to protect the supercoiled DNA from the threat of virus-driven energy theft.

The reverse logic is typical of theorists who do not understand why I claim that energy is information.

See for comparison: UV light activates 43 genes when DNA is damaged from The 2000 T. H. Morgan Medal Essay: H. J. Muller and the Nature of the Gene

The “nature” of the gene can now be compared to what is known about the energy-dependent de novo creation of genes  For example, a recent search for the termmicroRNA” returned a link to this published work. “Genetic 3’UTR variation is associated with human pigmentation characteristics and sensitivity to sunlight

One energy-dependent 3’UTR variation links sensitivity to the anti-entropic virucidal energy of sunlight to the physiology of reproduction in species from microbes to humans via microRNA flanking sequences and hydrogen-atom transfer in DNA base pairs in solution. Everything currently known to serious scientists appears to link endogenous RNA interference to healthy longevity. All experimental evidence of biologically-based facts also links virus-driven energy theft to all pathology.
My conclusion seems warranted. The energy-dependent de novo creation of genes links precision medicine to world peace by removing any religious views from the context of facts about creation.
For example, the newest member of my RNA-mediated FB group is from Turkey, which is where the Islamic creationist who wrote this book is gaining a large following. The Miracles of Smell and Taste
If the differences between Islam and Christianity can be linked from sunlight to the energy-dependent de novo creation of all biodiversity, could the similarities in the Abrahamic religions prevail? If so, I would use the similarities to link creation to the weekend resurrection of the bacterial flagellum in P. fluorescens, which gets its name from its innate ability to use light as a source of food energy?
See: Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system

…this system enables us to understand the adaptive process in detail at the genetic and phenotypic level. We identified a tractable model for gene network evolution and observed…

This “tractable model” is important enough to be viewed in context of this claim about the genetic networks in E. coli.
See: Biodiversity is autocatalytic

…the metabolic network of Escherichia coli forms a large autocatalytic set of close to 1800 reactions (Sousa et al., 2015). As far as we know, this is the first formal proof that living organisms (or at least essential parts thereof) are indeed autocatalytic sets.

As far as I know, there is no such thing as an autocatalytic set. If all 1800 reactions are not energy-dependent, they must arise automagically in the context of virus-driven energy theft and genomic entropy. If not, pseudoscientists must expect serious scientists to believe in claims like this: Physicists make the case that our brains’ learning is controlled by entropy
The fact that RNA methylation links energy-dependent learning and memory to the survival of all living genera via the physiology of pheromone-controlled reproduction seems to be unimportant to journalists like Fiona Macdonald who also wrote this article.
We Just Got More Evidence That The 2 Human ‘Sex Pheromones’ Don’t Actually Exist

“My major concern with the experiments in this study is that they were not rigorously designed and conducted,” Zhou explained.

Martha McClintock, a behavioural neuroscientist at the University of Chicago in Illinois, who wasn’t involved in this research and has been the driving force behind promoting AND and EST as pheromones, also told Science that the effect of the two chemicals could be more subtle than we’re currently expecting.

“There’s no doubt that this compound, even in tiny amounts, affects how the brain functions,” she added.

How much of an effect on hormones could be linked to the affect of a pheromone behavior?
See for comparison: In Battle for Real Estate, a Disordered Protein Wins Out

“Discovering CITED2’s ability to win these battles is a paradigm shift,” said Wright, senior author of the new study.

The new study suggests that it may be more efficient to mimic nature’s own response and use a CITED2-like drug to knock HIF-1α away.

The paradigm shift can be viewed in the context of how “nature” used intrinsically disordered proteins to achieve the biophysically constrained nutrient energy-dependent stability of pheromone-controlled supercoiled DNA. The nature of the response must be linked to the transgenerational epigenetic inheritance of all morphological and behavioral phenotypes in all living genera. That fact provides comic relief for serious scientists who understand how much pseudoscientific nonsense these authors included in a peer-reviewed publication in “Nature”
If you have a subscription, see: Hypersensitive termination of the hypoxic response by a disordered protein switch and watch for more reports on the “nature” and the magic of emergence and evolution of energy-dependent endogenous RNA interference and RNA-mediated cell type differentiation, which must link amino acid substitutions and chromosomal inheritance to all biophysically constrained biodiversity.
See also: Structural diversity of supercoiled DNA
See also: RNA Structural Modules Control the Rate and Pathway of RNA Folding and Assembly
These authors claim that nature may have harnessed the ability to generate kinectically controlled alternative RNA structures such as riboswitches, which change the dominant pathway of chemistry folding to fit the response that links single nucleotide changes from RNA-mediated protein folding pathways to the structure and function of RNAs via ‘deconstruction and reconstitution.’ They suggest the magic of ‘deconstruction and reconstitution.’ is a viable strategy for understanding how the overwhelming systems complexity of molecular mechanisms links complex RNA structures to conformational transitions, which they do not seem to realize are energy-dependent and biophysically constrained.
See also: Why Evolution Is Ageist

Currently, Martin’s lab is searching for genes that maintain homeostasis. His hypothesis is that something occurs to these cells later in life that increases the molecular “drift” of old age that results in cell-to-cell variation. “This drift might take on a life of its own after the reproductive age,” Martin says, “And if you get drift outside of a certain window of homeostasis, it’s possible you can’t come back.”

Homeostasis is energy-dependent and it is maintained by supercoiled DNA. Nothing about healthy longevity compare to pathology occurs outside the context of energy-dependent changes in the microRNA/messenger RNA balance.
See for examples: Nutrient-dependent/pheromone-controlled adaptive evolution: a model

…the epigenetic ‘tweaking’ of the immense gene networks that occurs via exposure to nutrient chemicals and pheromones can now be modeled in the context of the microRNA/messenger RNA balance, receptor-mediated intracellular signaling, and the stochastic gene expression required for nutrient-dependent pheromone-controlled adaptive evolution. The role of the microRNA/messenger RNA balance (Breen, Kemena, Vlasov, Notredame, & Kondrashov, 2012; Duvarci, Nader, & LeDoux, 2008; Griggs et al., 2013; Monahan & Lomvardas, 2012) in adaptive evolution will certainly be discussed in published works that will follow.

There are now more than 58,000 published works on microRNAs. This was published yesterday: Monitoring integrity and localization of modified single-stranded RNA oligonucleotides using ultrasensitive fluorescence methods.

The lifetime of the RNA in the cells could be explained by a balance between release of the oligonucleotides from endosomes, degradation by RNases and subsequent depletion from the cells.

The energy-dependent lifetime of messenger RNA links microRNAs to cell type stability via RNA-mediated amino acid substitutions in supercoiled DNA. Measuring fluorescence is an indicator of the differentiation of all cell types in all individuals of all living genera. Virus-driven energy theft links the degradation of messenger RNA to all pathology.

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