Cytosis in the light of evolution
(click to enlarge)
Excerpt 1 (with my emphasis)
Evolutionary Biology bring together a collection of articles exploring how evolutionary principles applied across the spectrum of biology can shed light on a diverse range of topics from molecules to ecosystems, and with a particular emphasis on human genetics, interactions with the environment, and health and disease. Selected research articles will be included in addition to invited reviews and comment.
My 2014 invited review of nutritional epigenetics was returned without review. Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems. Since then, the speed of light on contact with water has been linked to all nutrient energy pheromone-controlled biophysically constrained cell type differentiation.
My 2014 invited review of ecological adaptations in the context of nutritional epigenetics was returned without review by the guest editors of the journal “Nutrients.”
Excerpt 2 (with my emphasis)
We will consider Research manuscripts of exceptional interest on the following topics:
• Evolution of morphological change
• Understanding and treating disease in the light of evolution
• Origins of evolutionary complexity
• Human evolutionary biology in a post-genomic era
• Anthropogenic effects on evolution
• Evolutionary insights into genome variation, and vice versa
• Host-parasite interactions
• Evolutionary lessons from large-scale genomics
• Insights from ancient DNA on human origins
• Molecular mechanisms of evolution
• Applied microbial evolution
• Evolutionary ecology
• Genomics and the evolution of development
Riding the Evolution Paradigm Shift With Eugene Koonin
…the new understanding of evolution needs to integrate what we now know about viruses and virus-host interactions which, from my own perspective, has been absolutely one of the key factors of all evolution since the emergence of cells — well, actually even before the emergence of cells.
Kalevi Kull: Censorship & Royal Society Evo Event
Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge.
Excerpt 3 (with my emphasis)
Guest Editors: Brian Charlesworth, Jonathan Howard, Laurence Hurst, Philip Ingham, Alexander Johnson, Marc Kirschner, Eugene Koonin, Sean Munro.
The works of these guest editors have ignored the issues of Host-parasite interactions that serious scientists have placed into the context of the Molecular mechanisms of evolution, in attempts to find others who Combating Evolution to Fight Disease
Darwin probably anticipated the insemination of population genetics that led to the bastardization of his detailed observations in the “Modern Synthesis.” He politely insisted that ‘conditions of life’ be considered before natural selection.
There are two ‘conditions of life.’ It is nutrient-dependent and pheromone-controlled. Rosenberg and Queitsch now note the work with Dobzhansky’s rarely acknowledged claim: “I am a creationist and an evolutionist.” They also declare the need for “Deep understanding of the mechanisms that generate variation at the molecular level…”
Deep understanding of the ‘conditions of life’ does not come from theory.
Problems with the “modern synthesis” now lead us back to the facts about biologically-based cause and effect that Darwin and Dobzhansky approached with humility, which are the same biological facts that evolutionists approached with ignorance about behavioral affects and the arrogance that accompanies that ignorance. Rosenberg and Queitsch echo the sentiments of those who have been subjected to academic suppression.
Clearly, however, “nothing in evolution makes sense except in the light of biology” is not an exaggeration. It is a common sense statement about the biologically plausible genesis of functional cell types. Population genetics and evolutionary theories abandoned the biophysical constraints of ecological variation and the physiology of reproduction, which enable epigenetically-effected nutrient-dependent pheromone-controlled receptor-mediated ecological adaptations and species diversity via the complexities of protein folding and niche construction.
It’s time for biophysicists to tell theorists and pathologists how to differentiate between theories about the genesis of different cell types and the biological facts about the nutrient-dependent pheromone-controlled ecological adaptations that enable the genesis of different cell types in individuals of different species. Simply put, it’s time to stop trying to explain ecological adaptations in the context of mutations and evolution.
See also: Cytosis
A board game taking place inside a human cell! Players compete to build enzymes, hormones and receptors and fend off attacking Viruses!
Cytosis is a worker placement game that takes place inside a Human Cell! Players utilize the organelles within a cell to collect cellular resources such as mRNA from the Nucleus, Lipids from the Smooth E.R., ATP from the Mitochondria, etc. and score points when they use these resources to complete Hormones, Receptors or Enzymes! 2 to 5 Players, Ages 10 +, Plays in 50 to 75 mins – (Shipping Aug/Sept 2017 – US, EU, CA & AU will ship from WITHIN their country / region)
See also: The Interaction between Epigenetics, Nutrition and the Development of Cancer This article belongs to the Special Issue Nutritional Epigenetics, and Lynnette Ferguson was one of the guest editors who returned my invited review.
…“later life” epigenetic modifications in response to dietary intervention are the focus of this paper. The epigenetic modifications investigated include DNA methylation, histone modifications and the influence of microRNAs.
See for comparison: Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems
This atoms to ecosystems model of ecological adaptations links nutrient-dependent epigenetic effects on base pairs and amino acid substitutions to pheromone-controlled changes in the microRNA / messenger RNA balance and chromosomal rearrangements. The nutrient-dependent pheromone-controlled changes are required for the thermodynamic regulation of intracellular signaling, which enables biophysically constrained nutrient-dependent protein folding; experience-dependent receptor-mediated behaviors, and organism-level thermoregulation in ever-changing ecological niches and social niches. Nutrient-dependent pheromone-controlled ecological, social, neurogenic and socio-cognitive niche construction are manifested in increasing organismal complexity in species from microbes to man. Species diversity is a biologically-based nutrient-dependent morphological fact and species-specific pheromones control the physiology of reproduction. The reciprocal relationships of species-typical nutrient-dependent morphological and behavioral diversity are enabled by pheromone-controlled reproduction. Ecological variations and biophysically constrained natural selection of nutrients cause the behaviors that enable ecological adaptations. Species diversity is ecologically validated proof-of-concept. Ideas from population genetics, which exclude ecological factors, are integrated with an experimental evidence-based approach that establishes what is currently known. This is known: Olfactory/pheromonal input links food odors and social odors from the epigenetic landscape to the physical landscape of DNA in the organized genomes of species from microbes to man during their development.
If is not yet perfectly clear that the level of corruption in politics is paralleled by the level of corruption in academia, try to publish a refutation of neo-Darwinian pseudoscientific nonsense or a refutation of “Big Bang” cosmology. For example, I published a refutation of neo-Darwinism as a review in 2013:
See: Nutrient-dependent/pheromone-controlled adaptive evolution: a model
The facts about nutrient energy-dependent changes in microRNAs and the amino acid substitutions have since been placed into the context of the molecular mechanisms detailed by those who are combating evolution to fight disease via publication of more than 60,000 peer-reviewed journal articles that mention “microRNA“
And, In the light of evolution claims:
Evolutionary Biology bring together a collection of articles exploring how evolutionary principles applied across the spectrum of biology can shed light on a diverse range of topics from molecules to ecosystems, and with a particular emphasis on human genetics, interactions with the environment, and health and disease. Selected research articles will be included in addition to invited reviews and comment.
If evolutionary biologists were not among the most biologically uninformed theorists in the world, serious scientists who have linked energy-dependent changes in angstroms to ecosystems via supercoiled DNA would not be making fun of all pseudoscientists in this parody from the Zechiedrich lab (see: Structural diversity of supercoiled DNA).
https://youtu.be/gwy2lD1reos%20
See also: Advances in Non-Viral DNA Vectors for Gene Therapy
Viral vectors, however, have certain issues involving genome integration, the inability to be delivered repeatedly, and possible host rejection. Fortunately, development of non-viral DNA vectors has progressed steadily, especially in plasmid vector length reduction, now allowing these tools to fill in specifically where viral or other non-viral vectors may not be the best options.
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Antithetical conclusions (7)
3 MIN READ
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Antithetical conclusions (6)
3 MIN READ
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Anthetical conclusions
3 MIN READ
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RNAi: From magic bullet to billion dollar baby
4 MIN READ
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Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
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Pseudoscientists ignore what serious scientists prove
6 MIN READ
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From angstroms to ecosystems
7 MIN READ
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Food supplement or licensed immunostimulant?
6 MIN READ
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Virus-driven downsizing of the human brain (3)
4 MIN READ
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Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
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The end of neo-Darwinism
5 MIN READ
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Biophotonics, glycobiology, quantized biodiversity
4 MIN READ
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The Origin of Information (2)
6 MIN READ
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Light ‘drives’ adaptation; nothing ‘drives’ evolution
6 MIN READ
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Invisible dark matter
< 1 MIN READ
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Funding the Human Genome Project-Write
2 MIN READ
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RNA-mediated programming of E.coli
< 1 MIN READ
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Virus-driven downsizing of the human brain (2)
< 1 MIN READ
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Virus-driven downsizing of the human brain
2 MIN READ
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MicroRNAs and sexual orientation
8 MIN READ
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Innate immunity and multiplexing
7 MIN READ
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Amino acids and virus penetration
3 MIN READ
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Masters of deception about nature (2)
7 MIN READ
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The Mind’s Eyes (revisited)
10 MIN READ
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Cracking the Olfactory Code?
5 MIN READ
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RNA methylation, behavior, and disease
6 MIN READ
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Energy-dependent RNA methylation (10)
4 MIN READ
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Energy-dependent RNA methylation (8)
4 MIN READ
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Energy-dependent RNA methylation (7)
7 MIN READ
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Energy-dependent RNA methylation (5)
3 MIN READ
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Energy-dependent RNA methylation (3)
10 MIN READ
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Energy-dependent RNA methylation (2)
5 MIN READ
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Energy-dependent RNA methylation (1)
6 MIN READ
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Secular humanism and ecoterrorism
4 MIN READ
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War Games: False Flag Terrorism
5 MIN READ
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Energy-dependent biodiversity (2)
2 MIN READ
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The tipping point? 50,000 publications (3)
6 MIN READ
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Neo-Darwinism failed in 1995
3 MIN READ
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Countdown to Genetics and Genomics
< 1 MIN READ
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Energy-dependent creation and entropy
4 MIN READ
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RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
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RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
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RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
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RNA splicing, genetic variation, and disease
2 MIN READ
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Wasted Templeton Funding (3)
2 MIN READ
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Wasted Templeton Funding (2)
2 MIN READ
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Millions of water molecules vs years of evolution
2 MIN READ
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A bumper crop of virus-infected weeds and people
2 MIN READ
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Molecular Diagnostics: What is unprotected life (4)
2 MIN READ
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Molecular Diagnostics: What is unprotected life (3)
5 MIN READ
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Molecular Microbial Ecology
8 MIN READ
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Molecular Diagnostics: What is unprotected life? (2)
7 MIN READ
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Molecular Diagnostics: What is unprotected life?
2 MIN READ
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Creating and/or programming the immune system
< 1 MIN READ
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Half truths support theories without facts
4 MIN READ
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Ricki Lewis’ Time Machine (3)
5 MIN READ
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Creating nutrient-dependent life with enough genes to survive
3 MIN READ
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Confusing effects and affects of visual input
2 MIN READ
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Selective reporting of inferences: examples of pseudoscience
14 MIN READ
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Ignore the evidence: Rachel Feltman
5 MIN READ
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Virus-driven disorder prevention and health promotion
6 MIN READ
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Stress-linked population-level history dependence
5 MIN READ
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Do not miss the misrepresentations
2 MIN READ
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Energy dependent RNA-mediated immunity (3)
8 MIN READ
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RNA-mediated DNA modifications
5 MIN READ
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Science vs semantics
4 MIN READ
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From angstroms to ecosystems and entropy
2 MIN READ
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Bacteria see the light and they adapt (2)
5 MIN READ
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Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
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Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
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Creating gravity, nucleic acids, receptors, and supercoiled DNA
2 MIN READ
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Hydrogen-atom transfer in DNA base pairs (7)
5 MIN READ
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Organic Compounds and the Miracle of Smell and Taste
7 MIN READ
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Neuroscience Virtual Event vs AAAS Symposium
3 MIN READ
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Cancer: Evolution 2.0’s Blind Spot
13 MIN READ
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Ricki Lewis’ Time Machine (2)
6 MIN READ
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Blood test links atoms to ecosystems
2 MIN READ
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Teleophobes vs teleophiles: a recent history
2 MIN READ
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Ecological genomics: teleophobes respond (too late)
10 MIN READ
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Genes, orchid odors, and pheromones from blonds
5 MIN READ
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Amino acid substitutions, stress, and human behavior
3 MIN READ
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RNA methylation, RNA-directed DNA methylation, learning and memory
3 MIN READ
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Finding peace and π in the light of H bond energy
5 MIN READ
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Assumptions prove ignorance (2)
5 MIN READ
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Epigenetic (re)programming of behavior
4 MIN READ
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Assumptions prove ignorance
5 MIN READ
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Neo-Darwinian sink testing
2 MIN READ
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NORAD: air defense and defense against genomic entropy
7 MIN READ
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Life history transitions and RNA-mediated survial
2 MIN READ
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Did Dobzhansky see the UV light of creation?
10 MIN READ
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RNA-mediated theory killers (6) (7) (8) (9) (10)
5 MIN READ
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Manufacturing fossil “evidence”
4 MIN READ
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RNA-mediated theory killers (4)
9 MIN READ
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RNA-mediated theory killers (5)
2 MIN READ
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RNA-mediated theory killers (3)
7 MIN READ
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RNA-mediated theory killers
6 MIN READ
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Natural cooperation and Evolution 2.0
6 MIN READ
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A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
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Organization of biological sequences
2 MIN READ
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Virally derived RNA molecules and cell types
2 MIN READ
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Positive feedback loops and epigenetic traps
2 MIN READ
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Stress-perturbed mitochondrial dysfunction (2)
5 MIN READ
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Behavioral Immune System model
4 MIN READ
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Stress-perturbed mitochondrial dysfunction
4 MIN READ
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Sensationalizing no new mechanism
2 MIN READ
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Too complex for the Complex Biological Systems Alliance
4 MIN READ
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Receptor methylation controls behavior
2 MIN READ
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Virus, transposon and plasmid evolution
< 1 MIN READ
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Models are not theories (2)
2 MIN READ
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Models are not theories (1)
2 MIN READ
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Can veterans and other prisoners escape pseudoscience?
2 MIN READ
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Unraveling the secrets of RNA-mediated events
2 MIN READ
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Ecological speciation. Get it, theorists?
< 1 MIN READ
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Designing, engineering, and protecting biodiversity
3 MIN READ
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The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
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Skip the politics; embrace the facts
5 MIN READ
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Neo-Darwinian logic is nonsense
3 MIN READ
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FREE* SAMPLE: Histone modification
4 MIN READ
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Biophysically constrained or unconstrained?
2 MIN READ
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Mutated mitochondrial genes vs Supercoiled DNA
2 MIN READ
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Mystery machine vs medical intelligence
2 MIN READ
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Molecule of life vs animal experiments
< 1 MIN READ
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Keep the gay gene theory?
< 1 MIN READ
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Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
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