From E. coli to monkeys and mankind: Theories vs models (4)
Tagging and un tagging occurs at Ser214, Thr231 and Ser262 at least in order to attach to microtubules in good neurons along the axon highways. Interactions of these affect the PSD as well such as Ser212/Thr214, Ser202/Thr205, and Thr231 by altering the tau interaction with the PSD.
Tau is called a “microtubule associated protein”, one of many stabilizing and regulating the vast amount of shapes that microtubules form. The gene that makes tau is called MAPT for microtubule-associated protein tau gene.
Tau is also important in the nucleus. It binds to RNA by electro chemical interactions and it may also help stabilize RNA and DNA structures in the nucleus, as well as microtubules. It is possible that this interaction with RNA is part of the problem that forms aggregates of abnormal tau. One of the tau variants (4R) is better at helping microtubules.
J.A. Parker and John Hewitt are among the others who will recognize the degree of plagiarism in this blog post by Jon Lieff. Both journalists have reported either directly, or indirectly, on the link from virus-driven energy theft to pathology. For example J.A. Parker specifically linked the virus-driven damage to energy-dependent changes in microtubules and damage to quantum souls.
That fact forces all plagiarists to reinvent their ridiculous theories at the same time they try to include obvious facts about how nutrient energy-dependent RNA-mediated amino acid substitutions in supercoiled DNA protect all organized genomes from the virus-driven degradation of messenger RNA.
Jon Lieff writes about tagging and untagging, which occurs at Ser214, Thr231, and Ser262 to obfuscate the fact that “tagging” is energy-dependent and RNA-mediated. The tagging is RNA-directed DNA methylation and untagging is linked from virus-driven energy theft to the degradation of messenger RNA in all organized genomes. When viruses steal the energy that links amino acid substitutions to cell type differentiation, the degradation of messenger RNA links mutations to all pathology.
The magnitude of deception that continues to link the plagiarism to failed efforts to prevent or effectively treat all pathology is increasing. That suggests the plagiarists recognize the facts, which is why they must continue to obfuscate them for as long as is humanly possible.
In a few more months, we will see the the plagiarist’s time has run out. The cell biology game Cytosis will eliminate all the games played by theorists because their games do not start with the creation of energy-dependent microRNAs. Until then, follow the scientific progress here.
Current approaches to the neurosciences are naïve and often misguided. Contemporary researchers are hopelessly enthusiastic about computer simulations, wiring diagrams or connectomes, and brain activity maps.
…the genomes of two independent gene therapy recipients had sustained more than 1,500 single-nucleotide mutations and more than 100 larger deletions and insertions. None of these DNA mutations were predicted by computer algorithms that are widely used by researchers to look for off-target effects.
See for comparison: Physicists Claim the Soul Exists in a Quantum State After Death
Richard P. Feynman presciently predicted that theoretical physicists would be surprised to learn how quantized energy is linked to quantum souls in the context of how supercoiled DNA is created and maintained during times of ecological variation that must be linked from amino acid substitutions to ecological adaptations.
See also: Quantum Souls youtube channel