Epigenetic effects of stress by Bruce McEwen (2)
(click to enlarge)
Summary:
…rapid mRNA turnover starts with the energy-dependent de novo creation of microRNAs and ends with the virus-driven degradation of messenger RNA, which links mutations to all pathology.
See also: Epigenetic effects of stress by Bruce McEwen (1)
Summary:
In the early 1990’s, Bruce McEwen inspired my life’s works, which link the epigenetic effects of nutrient-stress and/or social stress to the fact that RNA biosynthesis is ATP-dependent. That fact helped all serious scientists link the virus-driven energy theft of quantized energy to the degradation of messenger RNA, which links mutations to all pathology.
Pseudoscientists refuse to accept that fact.
New research uncovers the secrets of photosynthesis that could help develop computer technology
Energy and charge transfer is what drives photosynthesis and any solar-to-chemical or electrical-to-chemical energy conversion.
That fact links the anti-entropic virucidal energy of sunlight from the de novo creation of microRNAs to all biodiversity. Bruce McEwen published on the role that microRNAs play in: Characterization of the vulnerability to repeated stress in Fischer 344 rats: possible involvement of microRNA-mediated down-regulation of the glucocorticoid receptor (2008)
We also identified that microRNA (miR)-18a inhibited translation of GR mRNA in cultured neuronal cells and that increased expression of miR-18a in the PVN was observed in F344 rats compared with SD rats. These strain differences in GR protein levels were not found in the hippocampus and prefrontal cortex, and the expression of miR-18a was much lower in these brain regions than in the PVN. Our results suggest that F344 rats could be a useful animal model for studying vulnerability to repeated stress, and that miR-18a-mediated down-regulation of GR translation may be an important factor to be considered in susceptibility to stress-related disorders.
See also: Early Life Stress Enhances Behavioral Vulnerability to Stress through the Activation of REST4-Mediated Gene Transcription in the Medial Prefrontal Cortex of Rodents (2010)
Figure 3.
Expression analyses of mRNAs of RE-1-containing genes and brain-enriched pre-microRNAs in the mPFC of the maternally separated rats. A, B, The expression of mRNAs (A) and pre-microRNAs (B) of a variety of RE-1-containing genes in the mPFC of AFR, HMS15, and HMS180 rats at P14 were quantified by Q-PCR (n = 6 for all groups). C, D, The expression of mature microRNAs in the mPFC of AFR, HMS15, and HMS180 rats at P14 were quantified by Northern blotting analysis (n = 5–6 for each group). E, The mRNA and pre-microRNA expression of RE-1-containing genes in the mPFC of adult AFR, HMS15, and HMS180 rats were quantified by Q-PCR (n = 6 for all groups). *p < 0.05.
Bruce McEwen subsequently linked what is known about energy-dependent changes in single nucleotide polymorphisms to effects of hormones on behavior in mice and humans via a food energy-dependent biophysically constrained amino acid substitution.
See: Stress dynamically regulates behavior and glutamatergic gene expression in hippocampus by opening a window of epigenetic plasticity (2015)
Excitatory amino acids play a key role in both adaptive and deleterious effects of stressors on the brain, and dysregulated glutamate homeostasis has been associated with psychiatric and neurological disorders. Here, we elucidate mechanisms of epigenetic plasticity… In WT mice after CRS and in unstressed mice with a BDNF loss-of-function allele (BDNF Val66Met), we show that the epigenetic activator of histone acetylation, P300, plays a pivotal role in the dynamic up- and down-regulation of mGlu2 in hippocampus via histone-3-lysine-27-acetylation (H3K27Ac) when acute stressors are applied. These hippocampal responses reveal a window of epigenetic plasticity that may be useful for treatment of disorders in which glutamatergic transmission is dysregulated.
See also: Multiplexed gene control reveals rapid mRNA turnover (open access)
The rapid mRNA turnover starts with the energy-dependent de novo creation of microRNAs and ends with the virus-driven degradation of messenger RNA, which links mutations to all pathology.
“Sometimes it is hard to believe that scientists could have unknowingly worked with methods that produce inconsistent results for almost 30 years”, says Becskei.
The synthesis of RNA in isolated thymus nuclei is ATP dependent.
The fact that some researchers still do not know that the synthesis of RNA is energy-dependent makes it impossible for them to link virus-driven energy theft from the degradation of messenger RNA to mutations and all pathology in all living genera.
It will soon become “child’s play” for anyone over 10 years old. See: Cytosis: A Cell Biology Board Game
A board game taking place inside a human cell! Players compete to build enzymes, hormones and receptors and fend off attacking Viruses!
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Your indifference is killing you and others (4)
4 MIN READ
0
Automagical protein creation sans energy
9 MIN READ
0
Solar analemma with a total solar eclipse
2 MIN READ
0
The Origin of Information (4)
4 MIN READ
0
Can protein folding chemistry be understood by theorists?
5 MIN READ
0
Irreconcilable differences: food energy vs de novo assembly
2 MIN READ
0
New Testament Book Cover Refutes Theistic Evolution
7 MIN READ
0
Energy-dependent physical and biophysical constraints (10)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (9)
3 MIN READ
0
Energy-dependent physical and biophysical constraints (8)
5 MIN READ
0
Energy-dependent physical and biophysical constraints (7)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (6)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (5)
7 MIN READ
0
Energy-dependent physical and biophysical constraints (4)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (2)
4 MIN READ
0
Energy-dependent physical and biophysical constraints (1)
5 MIN READ
0
Cell type assembly and the space-time continuum
2 MIN READ
0
Richard P. Feynman refuted theistic evolution
5 MIN READ
0
Epigenetic effects of stress by Bruce McEwen (1)
9 MIN READ
1
The emergence of light as energy from a life-giving star
11 MIN READ
2
God’s shrinking role in salvation (3)
9 MIN READ
0
God's shrinking role in salvation (3)
9 MIN READ
0
MicroRNAs GnRH and the failure of sex research
7 MIN READ
0
God’s shrinking role in salvation
8 MIN READ
0
Hard Science vs the neo-Darwinian “magic box”
9 MIN READ
0
Infections and age change the odor of wine and people
4 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models (5)
5 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models
7 MIN READ
0
Food energy-dependent epigenetic adaptation (3)
3 MIN READ
0
Food energy-dependent epigenetic adaptation (2)
< 1 MIN READ
0
Food energy-dependent epigenetic adaptation
11 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (5)
4 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (3)
5 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability
8 MIN READ
0
What energy source do proteins prefer?
6 MIN READ
0
Energy-dependent microRNA biogenesis
4 MIN READ
0
Draining the academic swamp of parasites
3 MIN READ
0
The death of human ethology via ecology
7 MIN READ
0
Ignoring peer review, ATP, and microRNA biosynthesis
5 MIN READ
0
Dispensing with all pseudoscientific nonsense about evolution (1)
5 MIN READ
0
Dispensing with March for Science Dispatches (2)
2 MIN READ
0
Dispensing with March for Science Dispatches (1)
2 MIN READ
0
Virus-driven downsizing of the human brain (4)
2 MIN READ
0
Open Science: Closed to facts about microRNAs
6 MIN READ
0
What is life without sunshine?
2 MIN READ
0
Viruses in pathogenic variants disrupt alternative splicings (2)
3 MIN READ
0
Respiration-dependent endogenous RNA interference
4 MIN READ
0
Epigenetically-effected nucleosome repositioning sheds Dobzhansky’s light on evolution
3 MIN READ
0
Cytosis: Gameplay Runthrough
3 MIN READ
0
Synthetic RNA-based switches
2 MIN READ
0
Sunlight bursts the social bubble of physics and math
3 MIN READ
0
Functionally interdependent editing and methylation
4 MIN READ
0
Cytosis: Biology Content
7 MIN READ
0
Light-activated feedback loops vs self-organization of ecosystems
7 MIN READ
0
Harvard researchers support young earth creationism
< 1 MIN READ
0
Cytosis: A Cell Biology Board Game
< 1 MIN READ
0
Sal Giardina: apologetics revisited
8 MIN READ
0
Virulence and your UTI
2 MIN READ
0
Life in your UV light-constrained galaxy
5 MIN READ
0
Food for thought: Penrose v Ellis (3)
4 MIN READ
0
Thinking about energy is not radical re-thinking
6 MIN READ
0
Magnussen’s “Faith fools” keep the faith
3 MIN READ
0
Energy-dependent pheromone-controlled entropy (3)
2 MIN READ
0
Energy-dependent pheromone-controlled entropy (4)
3 MIN READ
0
Proof: Sunlight is energy as information
< 1 MIN READ
0
Energy-dependent pheromone-controlled entropy (1)
4 MIN READ
0
Sunlight: the essence of precision medicine and world peace
6 MIN READ
0
The essence of precision medicine: drug targets or healthy longevity?
4 MIN READ
0
Ab initio cell wall invention, emergence, and evolution (2)
8 MIN READ
0
RNA-mediated adult learning, memory, and neurogenesis
3 MIN READ
0
Energy-dependent allelic imbalances, viruses, and pathology
3 MIN READ
0
Ab initio cell wall invention, emergence, and evolution (1)
2 MIN READ
0
Biologically uninformed biologists fight back and lose
3 MIN READ
0
Theistic evolutionists fight back and lose (2)
4 MIN READ
0
Theistic evolutionists fight back and lose
4 MIN READ
0
Young earth creationists refute theistic evolution
3 MIN READ
0
Emily Witkin refutes theistic evolution
2 MIN READ
0
Wikipedia refutes theistic evolution
4 MIN READ
0
RNA editing refutes theistic evolution
4 MIN READ
0
Pseudoscientists fail to refute theistic evolution
4 MIN READ
0
Stuart Kauffman refutes theistic evolution
3 MIN READ
0
Francis S. Collins refutes theistic evolution
6 MIN READ
0
Happy Darwin Day (2017)
4 MIN READ
0
George Church refutes theistic evolution (3)
5 MIN READ
0
George Church refutes theistic evolution (2)
2 MIN READ
0
George Church refutes theistic evolution
5 MIN READ
0
Natural selection for codon optimality and quantum viruses
5 MIN READ
0
Physicists: Desperate Acts (revisited)
6 MIN READ
0
Energy as information and constrained endogenous RNA interference (3)
4 MIN READ
0
Fighting for virus-driven pathology
5 MIN READ
0
Dobzhansky 1973 and precision medicine (5)
3 MIN READ
0
Dobzhansky 1973 and precision medicine (4)
5 MIN READ
0
Dobzhansky 1973 and Precision Medicine (2)
5 MIN READ
0
Trump’s appeal to common sense (2)
3 MIN READ
0
Science journalists or paid propagandists? (4)
6 MIN READ
0
Dobzhansky 1973 and precision medicine
6 MIN READ
0
Twisted theories and weaponized facts
3 MIN READ
0
Autophagy: from pre-mRNAs to microRNAs, enhancers, QTLs et al.
6 MIN READ
0
Mutations: the “driving force” behind human brain complexity?
6 MIN READ
0
Mutations: the "driving force" behind human brain complexity?
6 MIN READ
0
Science journalists or paid propagandists? (2)
3 MIN READ
0
Critical values expose virus-driven energy theft (2)
4 MIN READ
0
Critical values expose virus-driven energy theft
6 MIN READ
0
Theorists sell hidden energy
3 MIN READ
0
Anti-entropic energy and the “Music of Life”
3 MIN READ
0
Anti-entropic energy and the "Music of Life"
3 MIN READ
0
Chirality is reality
6 MIN READ
0
Energy-dependent hydrogen bonds in supercoiled DNA
7 MIN READ
0
Energy-dependent chirality (2)
3 MIN READ
0
Energy-dependent chirality
6 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5 MIN READ
0
Vietnam Veterans and others with glioblastoma
3 MIN READ
0
Energy-dependent sensory maps (1996-2016)
5 MIN READ
0
Energy-dependent oscillating gene networks organize life
4 MIN READ
0
2016 obfuscated facts about energy as information
5 MIN READ
0
More refutations of neo-Darwinian nonsense
7 MIN READ
0
Sudden death indel polymorphism
4 MIN READ
0
Anti-entropic virucidal energy as information
10 MIN READ
0
Bio-functional information
3 MIN READ
0
Bird-brained theorists
< 1 MIN READ
0
Explorers who do not know what is known
4 MIN READ
0
Energy-dependent natural translational selection
4 MIN READ
0
Autophagy is the antiphage defense strategy
3 MIN READ
0
Energy-dependent de novo creation and neurogenesis
7 MIN READ
0
Theories vs facts about polycombic adaptation
3 MIN READ
0
Tasting light links energy from creation to adaptation
9 MIN READ
0
Politicized science: The demise of RNA-mediated.com?
3 MIN READ
0
Combating evolution: Battlefield medicine vs politicized science
6 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Metabolic Phenotyping Research
2 MIN READ
0
Happy biophysically constrained Thanksgiving (in the USA)
3 MIN READ
0
De novo gene creation: Ignoring the experimental evidence
7 MIN READ
0
Energy-dependent coulombic, autophagic, polycombic healthy longevity
4 MIN READ
0
Light, behavior and autophagy, a gender-specific risk factor
4 MIN READ
0
Controlled amino acid treatment of all pathology
4 MIN READ
0
Energy-dependent purifying selection / autophagy (2)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (3)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (4)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (5)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (6)
3 MIN READ
0
Energy-dependent purifying selection / autophagy
2 MIN READ
0
Optogenetics: Let there be virucidal light!
2 MIN READ
0
Base pairs, amino acids and phenotypes
10 MIN READ
0
Survivors of RNA-mediated terrorism
5 MIN READ
0
RNA-mediated terrorism
< 1 MIN READ
0
Building delicious base pairs in class. It’s elementary Watson and Crick
3 MIN READ
0
Building delicious base pairs in class. It's elementary Watson and Crick
3 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (8)
4 MIN READ
0
Energy-dependent maternal-to-zygotic transition
6 MIN READ
1
Virus-driven mutation or amino acid substitution
5 MIN READ
0
Epigenetically effected energy-dependent fluorescence (2)
6 MIN READ
0
Epigenetically effected energy-dependent fluorescence
5 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (7)
3 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (5)
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (4)
< 1 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (3)
< 1 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (2)
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution
< 1 MIN READ
0
From precis to pre-mRNA and proof of concept in F1, F2, F3
6 MIN READ
0
From Precis to Proof in 6000 years
9 MIN READ
0
Coulombic interactions facilitate polycombic adaptation
5 MIN READ
0
Top-down adaptation vs bottom-up evolution
6 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (2)
3 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
Polycombic ecological adaptation as a science, not a theory
3 MIN READ
0
Biological evolution as a philosophy, not a science
6 MIN READ
0
Attacking Young Earth Creationists
5 MIN READ
0
Did evolution autophosphorylate your kinases? (3)
2 MIN READ
1
Predictable idiosyncratic evolved convergence
3 MIN READ
0
The human virome (revisited)
4 MIN READ
0
The natural success of RNAi and failed treatment
7 MIN READ
0
Pheromone-controlled autophagy
4 MIN READ
0
Hecatombic non-specific mutation-driven evolution
5 MIN READ
0
Virus-mediated hecatombic evolution
2 MIN READ
0
Hecatombic evolution via oncocers and oncohistones
9 MIN READ
0
Did evolution autophosphorylate your kinases? (2)
5 MIN READ
1
Nutrient-dependent autophagy
3 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy (2)
6 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy
3 MIN READ
0
Life is energy-dependent task management (2)
3 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
Hypothesis free pseudoscience vs facts (5)
6 MIN READ
0
Hypothesis free pseudoscience vs facts (4)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (2)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (1)
5 MIN READ
0
Chromatin: The structure of DNA (2)
8 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
A working model of “captured” genes
6 MIN READ
0
DNA repair via junk DNA (2)
5 MIN READ
0
The Aquatic Ape / Waterside Ape divergence
6 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
Displays of ecological adaptation (2)
3 MIN READ
0
DNA repair via junk DNA (1)
5 MIN READ
0
Unconstrained mutations, Zika virus, Kallmann’s syndrome
4 MIN READ
0
Linking RNA structure to function
3 MIN READ
0
How did the innate immune system evolve?
4 MIN READ
0
The Aquatic Ape: New evidence?
4 MIN READ
0
Protecting 4 billion people from virus-driven entropy
< 1 MIN READ
0
Energy-dependent cellular communication
3 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Antithetical conclusions (7)
3 MIN READ
0
Antithetical conclusions (5)
4 MIN READ
0
Anthetical conclusions (2)
5 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
RNAi: From magic bullet to billion dollar baby
4 MIN READ
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
Pseudoscientists ignore what serious scientists prove
6 MIN READ
0
GC-rich neo-Darwinian train wreck
5 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (3)
< 1 MIN READ
0
Biophysically constrained cell type differentiation
3 MIN READ
0
Virus-driven downsizing of the human brain (3)
4 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
The end of neo-Darwinism
5 MIN READ
0
The Origin of Information (2)
6 MIN READ
0
Funding the Human Genome Project-Write
2 MIN READ
0
RNA-mediated programming of E.coli
< 1 MIN READ
0
Did “Nature” kill Steve Jobs? (2)
6 MIN READ
0
Did “Nature” kill Steve Jobs?
3 MIN READ
0
Virus-driven downsizing of the human brain (2)
< 1 MIN READ
0
MicroRNAs and sexual orientation
8 MIN READ
0
RNA methylation, learning, memory and behavior,
< 1 MIN READ
0
Innate immunity and multiplexing
7 MIN READ
0
RNA methylation (2)
7 MIN READ
0
Amino acids and virus penetration
3 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
Model vs theory: Progress report!
8 MIN READ
0
Masters of deception about nature (2)
7 MIN READ
0
Masters of deception about nature
8 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
Cracking the Olfactory Code?
5 MIN READ
0
RNA methylation, behavior, and disease
6 MIN READ
0
Modelling life scientifically: RNA-mediated events
12 MIN READ
0
Energy-dependent RNA methylation (9)
2 MIN READ
0
Energy-dependent RNA methylation (10)
4 MIN READ
0
Energy-dependent RNA methylation (8)
4 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (3)
10 MIN READ
0
Energy-dependent RNA methylation (2)
5 MIN READ
0
Energy-dependent RNA methylation (1)
6 MIN READ
0
War Games: False Flag Terrorism
5 MIN READ
0
Energy-dependent biodiversity (3)
7 MIN READ
0
Energy-dependent biodiversity
5 MIN READ
0
The tipping point? 50, 000 publications
4 MIN READ
0
Countdown to Genetics and Genomics
< 1 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
Wasted Templeton Funding (4)
3 MIN READ
0
Magic, Miracle, or Molecular Mechanism?
10 MIN READ
0
Molecular Diagnostics: What is unprotected life (3)
5 MIN READ
0
Molecular Diagnostics: What is unprotected life? (2)
7 MIN READ
0
Molecular Diagnostics: What is unprotected life?
2 MIN READ
0
Half truths support theories without facts
4 MIN READ
0
Ricki Lewis’ Time Machine (3)
5 MIN READ
0
Creating nutrient-dependent life with enough genes to survive
3 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Energy-dependent purpose vs teleophobic telorexia
12 MIN READ
0
Virus-driven disorder prevention and health promotion
6 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Jay R. Feierman: twenty years of antagonism
5 MIN READ
0
Energy dependent RNA-mediated immunity (6)
5 MIN READ
0
Energy dependent RNA-mediated immunity (5)
4 MIN READ
0
Energy dependent RNA-mediated immunity (4)
6 MIN READ
0
Energy dependent RNA-mediated immunity (3)
8 MIN READ
0
Science vs semantics
4 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands (2)
3 MIN READ
0
Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9 MIN READ
0
Bacteria see the light and they adapt
7 MIN READ
0
The Light and Darkness of “Evolution 2.0”
11 MIN READ
0
Neuroscience Virtual Event vs AAAS Symposium
3 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Virus-perturbed alternative splicings
3 MIN READ
0
The radical pair mechanism of ecological speciation
3 MIN READ
0
Center stage RNA-mediated events (since 1996)
3 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs (4)
4 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
Another failed rescue attempt
5 MIN READ
0
Stress-induced energy-dependent DNA repair
4 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Ecological genomics: teleophobes respond (too late)
10 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
Amino acid substitutions, stress, and human behavior
3 MIN READ
0
Finding peace and π in the light of H bond energy (2)
8 MIN READ
0
MicroRNA-mediated RNA epigenetics
2 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Epigenetic (re)programming of behavior (3)
5 MIN READ
0
Perry Marshall: too much information for atheist PZ Myers
3 MIN READ
0
Epigenetic (re)programming of behavior (2)
6 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
Neo-Darwinian sink testing
2 MIN READ
0
Did Dobzhansky see the UV light of creation?
10 MIN READ
0
Does metabolism link beneficial mutations to cancer?
10 MIN READ
0
RNA-mediated theory killers (5)
2 MIN READ
0
RNA-mediated theory killers (3)
7 MIN READ
0
RNA-mediated regulatory mechanisms link microbes to humans (3)
5 MIN READ
0
Nutrient-dependent trophic analogs (2)
6 MIN READ
0
RNA-mediated theory killers (2)
8 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (4)
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (5)
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
0
Teaching the biologically uninformed
3 MIN READ
0
MicroRNAs vs Red Queen hypothesis
4 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs
9 MIN READ
0
Neo-Darwinism vs the neocortex
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair
2 MIN READ
0
Nutrient-dependent trophic analogs
3 MIN READ
0
Virally derived RNA molecules and cell types
2 MIN READ
0
Plasma created by sunlight and RNA–mediated epigenetic heredity
2 MIN READ
0
Positive feedback loops and epigenetic traps
2 MIN READ
0
Stress-perturbed mitochondrial dysfunction (2)
5 MIN READ
0
Understanding cell type differentiation
3 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Sensationalizing no new mechanism
2 MIN READ
0
Too complex for the Complex Biological Systems Alliance
4 MIN READ
0
More re-evolved functional structures?
2 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
Conserved molecular mechanisms
< 1 MIN READ
0
Models are not theories (2)
2 MIN READ
0
Designing, engineering, and protecting biodiversity
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Controled Stem Cell Expansion
3 MIN READ
0
Neo-Darwinian logic is nonsense
3 MIN READ
0
700 million years of evolution?
5 MIN READ
0
Biophysically constrained or unconstrained?
2 MIN READ
0
RNA-mediated retrotransposon-mediated biodiversity
3 MIN READ
0
Mystery machine vs model (2)
2 MIN READ
0
Mystery machine vs model
2 MIN READ
0
Epigenetic inheritance of stress-perturbed protein folding
2 MIN READ
0
Preventing genomic entropy
4 MIN READ
0
Checkpoint checkmate: viruses lose if conditions of life win
< 1 MIN READ
0
Cancer: forward and reverse
2 MIN READ
0
Energy and evolution: another opinion?
2 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Virucidal effects on ecological speciation
5 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
The bug in the “holy grail” of evolution
4 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Viruses come alive: Tree of life pseudoscience
6 MIN READ
0
Hijacked light energy and vertebrate pathology
4 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
A 5-10K comparison of design principles to evolution
3 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Pathology: Eating and breathing viruses
2 MIN READ
0
Exosomes and the RNA-mediated future of medicine (3)
2 MIN READ
0
Exosomes and the RNA-mediated future of medicine
5 MIN READ
0
Multi-omic analysis features (SNPs, miRNA)
3 MIN READ
0
From fertilization to RNA-mediated events and back
2 MIN READ
0
Phytochemical link from the sun to cell types
2 MIN READ
0
Genome sequencing, cadherins, and quantum consciousness
6 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
A “new” code enables ecological adaptation
4 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
The “great filter” is an epigenetic trap
4 MIN READ
0
Information and communication (2)
6 MIN READ
0
Unraveling evolutionary pseudoscience
2 MIN READ
0
Rs3827760 is Val370Ala and EDARV370A
3 MIN READ
0
From “Blood Music” to Evolution 2.0
5 MIN READ
0
Olfaction & the octopus and human genomes (2)
4 MIN READ
0
Ecology replaces the extended evolutionary synthesis
4 MIN READ
0
The stability of organized genomes (4)
3 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
Epimutation.com: a domain of confusion
8 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
Viruses, amino acids, and somatic cell types
4 MIN READ
0
Big Bang Cosmology vs Reality
< 1 MIN READ
0
Hematopoiesis and practopoiesis
4 MIN READ
0
RNA-mediated morphological AND behavioral phenotypes
2 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Riding the wrong direction
3 MIN READ
0
Decreased phenotypic variation: Faith in Facts
7 MIN READ
1
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
The RNA-mediated sum of our parts
2 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
Amino acid substitutions are not mutations
2 MIN READ
0
“First” evidence
5 MIN READ
0
What I cannot create I eliminate from discussion
3 MIN READ
0
RNA-mediated development
2 MIN READ
0
Creating and maintaining the human virome
2 MIN READ
0
microRNAs, glycosylation, and genomes
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Viruses and the human-like microbiome
3 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
I forgot. How do mutations cause evolution?
4 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
Missing a fact: microRNAs are genomic biomarkers
4 MIN READ
1
Scientists lose. A sci-fi author gains credibility
2 MIN READ
0
Computing via phosphorylation and fixation
3 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Tissue type variation and expression of genes
< 1 MIN READ
0
From gut bacteria to breast milk and back
5 MIN READ
0
Chance mutations — not natural selection
5 MIN READ
0
Physics, chemistry, light, and life
2 MIN READ
0
Epigenetics vs the fossil record
4 MIN READ
0
An epigenetic mark links algae, worms, and flies
2 MIN READ
0
Pathology constrains X-linked evolution
2 MIN READ
0
Re-inventing a completely new thing
4 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
The Darwin Code by Greg Bear
13 MIN READ
0
Genetic chimerism and ecological adaptation
4 MIN READ
0
A genetic variant refutes neo-Darwinism
6 MIN READ
0
MicroRNAs and invasive phenotypes
< 1 MIN READ
0
The miRNA/mRNA balance: a suboptimal strategy?
2 MIN READ
0
Life: conserved ion and amino acid transporters
3 MIN READ
0
Deeply ingrained thoughts
< 1 MIN READ
0
Graphic misrepresentations of ecological adaptation
2 MIN READ
0
Methylation maintains cell type differences
3 MIN READ
0
Creating nothing but a theory (2)
4 MIN READ
0
Creating nothing but a theory
4 MIN READ
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Anti-entropic solar energy
5 MIN READ
0
Correctly modeling biological energy
2 MIN READ
0
Correctly modeling ecological adaptation
4 MIN READ
0
Virus-driven origin of life
2 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
Walk towards the light
< 1 MIN READ
0
Epigenetics Skeptism
5 MIN READ
0
What about birds?
5 MIN READ
0
Virus-driven cell type differentiation
2 MIN READ
0
RNA directed DNA methylation and cell types
4 MIN READ
0
Implicating microRNAs in cancer
2 MIN READ
0
Reverse phosphorylation
7 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
An epigenetic trap (the prequel)
5 MIN READ
0
Atheism: Arrogant, useless, and divisive ignorance
7 MIN READ
0
Nutritional epigenetics, exercise, and immune system integrity
4 MIN READ
0
What if Darwin was not still dead?
2 MIN READ
0
Military combat training to fight disease (2)
3 MIN READ
0
RNA-mediated epigenetic modification via DNA-methylation
4 MIN READ
0
How fast can evolutionary theory be changed?
5 MIN READ
0
Are viruses microRNAs? (2)
5 MIN READ
0
Are viruses microRNAs?
3 MIN READ
0
Sneaking up from behind (2)
3 MIN READ
0
Physicists: Desperate Acts
16 MIN READ
0
All of "like kind" in the (bigger) family
6 MIN READ
1
Environment epigenetically shapes the immune system
3 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
A single amino acid substitution differentiates cell types of E. coli
3 MIN READ
0
Jumping back: Science or Pseudoscience? (2)
2 MIN READ
0
Glycine and GnRH: Am I being pedantic?
4 MIN READ
0
Dual genomes: exposing the evolution industry
5 MIN READ
0
Meaningful dialogue, anonymous fools and idiot minions
4 MIN READ
0
RNA-mediated species specificity
2 MIN READ
0
Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
0
Biologists puzzled by evolved RNAs and decaying DNA
6 MIN READ
0
Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
0
Complex behaviors of cell types in cancer
6 MIN READ
0
RNA eclipses the importance of DNA to cell type differentiation
4 MIN READ
0
We need pattern recognition, not proclamations
3 MIN READ
0
In theory, or supported by experimental evidence?
5 MIN READ
0
It’s cell type differention, not cell fate determination (2)
3 MIN READ
0
Are evolutionary theorists 'nob ends'?
5 MIN READ
2
ALPHA GENOMIX
7 MIN READ
2
No excuses: Creation and the meaning of organismal complexity
7 MIN READ
0
Nutrient-dependent gene duplication in plants (but not animals?)
4 MIN READ
0
Evolutionary theorists and evolutionary theists live under rocks
< 1 MIN READ
0
No understanding of biodiversity
2 MIN READ
0
2014 and 2004 Nobel Prize in Medicine
3 MIN READ
0
RNA-mediated events: chromosomal rearrangements and genomic rearrangements
2 MIN READ
2
RNA-mediated genetic engineering (Part 2)
3 MIN READ
0
RNA-mediated genetic engineering
2 MIN READ
0
RNA-mediated events are not a matter of faith
2 MIN READ
0
Color vision refutes the evolutionary dogma of gene duplication
4 MIN READ
0
Unassailable evidence vs assumptions
4 MIN READ
0
Genomic surveillance ends our world of RNA-mediated ecological adaptations
2 MIN READ
0
Different physical locations and different molecular mechanisms of health and disease
2 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Physics denied; pseudoscientific nonsense accepted
2 MIN READ
0
Evolving DNA before RNA
4 MIN READ
0
Stop evolutionary theorists. Kill cancers
3 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Mathematical model: microRNA and epigenetic regulation
2 MIN READ
0
Can epigenetic inheritance occur without concurrent changes in morphology AND behavior?
3 MIN READ
0
Quantum physics meets Evolutionary Psychology News
2 MIN READ
0
Nutrient-dependent pheromone-controlled exercise-induced physiques
< 1 MIN READ
0
RNA-mediated species diversification from microbes to primates
3 MIN READ
0
Some neuroscientists think a mutation led to human language development
< 1 MIN READ
0
Behavior: The first response is RNA-mediated not genetically-determined
3 MIN READ
0
Evolutionary heritage or ecological adaptation? Racism versus reality
4 MIN READ
0
Insect homology and diversity attributed to mutations
2 MIN READ
0
Biophysically constrained beginnings of RNA and DNA
4 MIN READ
0
The quantum biology of consciousness
3 MIN READ
0
Genes and Race: Human History?
2 MIN READ
0
Ecologically linked adapted ants and brains
2 MIN READ
0
Darwinian theories vs Darwin's facts
2 MIN READ
0
Chromosomal rearrangements and ecological adaptations
4 MIN READ
0
Pheromone-controlled thermodynamics and cancer
2 MIN READ
0
Nutrient-dependent pheromone-controlled stickleback evolution
2 MIN READ
0
Understanding the role of mutations and evolution
4 MIN READ
0
Pheromones and cancer
4 MIN READ
0
More than speculation: adaptive evolution in species from microbes to man
2 MIN READ
0
