Human Idiocy: The failure to link energy from electrons to ecosystems

For example, the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla.

The food energy-dependent pheromone-controlled physiology of reproduction has now been linked from the the sense of smell in bacteria to prevention of cancer and the prevention of neurodegenerative diseases via changes in microRNAs.

Variable potentials for thermalized light and coupled condensates

They indirectly link the creation of light to energy as information.
Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression
They link energy as information from vitamin C to RNA-mediated DNA repair and cancer treatment.

The laws of attraction: Pheromones don’t lie, fruit fly research suggests

They link the metabolism of food energy to the physiology of pheromone-controlled reproduction in all living genera.
Olfaction Warps Visual Time Perception
They link the energy-dependent de novo creation of G-protein coupled receptors from the sense of smell in bacteria to our visual perception of mass and energy in the context of what is known about biophysically constrained energy-dependent protein folding chemistry and the time-space continuum.
See also: Species of Drosophila (1972) and Nothing in Biology Makes Any Sense Except in the Light of Evolution (1973)
In 1972 and in 1973, Dobzhansky linked “so called” electrons to the “so-called” alpha chains of hemoglobin in 3 different primate species via one amino acid substitution.

For example, the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla.

The food energy-dependent pheromone-controlled physiology of reproduction has now been linked from the the sense of smell in bacteria to prevention of cancer and the prevention of neurodegenerative diseases.
See: Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis
See also: Docosahexaenoic acid–mediated, targeted and sustained brain delivery of curcumin microemulsion
See also: Formulation and evaluation of anti-suicidal nasal spray of Thyrotropin releasing hormone
See also: Uncovering robust patterns of microRNA co-expression across cancers using Bayesian Relevance Networks
See also: Challenging the Modern Synthesis: Adaptation, Development, and Inheritance
Pattern recognition is limited among theorists who have not challenged the Modern Synthesis by presenting a model of how ecological variation must be linked to the physiology of reproduction and ecological adaptation. Successes and failures are detailed in this series of interviews.
Video interview about the death of Robin Williams
Superbugs, Bacteriophages and Phage Therapy: An Interview with James Kohl
Food Energy-Dependent Cell Type Differentiation Refutes Theory of Evolution
How to Treat Cancer as a Disorder of Energy Transfer
Charles Darwin Taught Conditions of Life, Not Mutations
Quantized Energy Links Olfaction from Angstroms to Ecosystems Part 1
Quantized Energy Links Olfaction from Angstroms to Ecosystems Part 2

Conclusion:

As an activist she interviewed once told her, she said, “‘Action is the antidote to despair.’”

See for comparison:   The major antigenic changes of the influenza virus are primarily caused by a single amino acid near the receptor binding site.

See my comment, which was removed from “Science,” but not from The Atlantic:

The Quest to End the Flu

See also: “Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution”

The idea of biophysical constraints seems antithetical to the idea of nature somehow selecting mutations that cause amino acid substitutions. However, I am not a biophysicist or evolutionary theorist.

The problem may be my focus on nutrient-dependent receptor-mediated amino acid substitutions in species from bacteria to humans (non-viral organisms). Since I am not a virologist or physicist, I’m not sure that the laws of physics apply to viruses and their replication.

If they do, natural selection for random mutations is not likely to result in amino acid substitutions because the thermodynamics of changes in organism-level thermoregulation preclude such randomness. Stability of protein biosynthesis and degradation that probably depends on protein folding must somehow be controlled. Besides, I don’t know how random mutations in viruses could be naturally selected for inclusion in the human virome (or in the virome of any organism capable of thermoregulating its thermodynamic intercellular signaling).

If the Second Law of Thermodynamics does not apply to viruses, which means the chemical bonds that enable the amino acid substitutions can form at random and somehow be naturally selected, the details of biophysical constraints in this article seems out of place, since I do not think in terms of constrained random mutations and natural selection in mutation-driven evolution.

Hopefully, someone with a background in biophysics will address my confusion in case others are confused. In addition, I wonder if the consequences of understanding the evolutionary mechanisms that govern viruses extend to consequences important to understanding the evolution of species from bacteria to humans via constrained random mutations and natural selection?

Men Who Eat More Fruits And Veggies Smell More Attractive To Women

“We’ve known for a while that odor is an important component of attractiveness, especially for women,” Ian Stephen, who helped conduct the small study, said in a recent interview with NPR. “Women basically found that men who ate more vegetables smelled nicer.”

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See also, this attempt to discuss what I have learned about pheromones and biophysically constrained healthy longevity for comparison to virus-driven pathology on my personal FB page.

James Kohl