Losers: rediscovering an epigenetic key

(click to enlarge)
Epigenetic mechanisms modulate differences in Drosophila foraging behavior
Little is known about how genetic variation and epigenetic marks interact to shape differences in behavior.
Reported as: An epigenetic key to unlock behavior change October 16, 2017
“One of the big questions in the Child & Brain Development program over the years has been how experience gets embedded in our biology and the mechanisms for that,” says Sokolowski.
See for comparison: See Brain on stress: How the social environment gets under the skin (2012)
Brain circuits are plastic and remodeled by stress to change the balance between anxiety, mood control, memory, and decision making. Such changes may have adaptive value in particular contexts, but their persistence and lack of reversibility can be maladaptive.
Adaptations are energy-dependent and biophysically constrained by the pheromone-controlled physiology of reproduction in all living genera.
Food energy links epigenetic effects on hormones to the affect of hormones on behavior.
See: The authors note that on page 17184, right column, first paragraph, line 4, “effect” should instead appear as “affect.”
See for comparison:
Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge. — Kalevi Kull
Sokolowski’s group is a group of losers. They failed to link food energy to biophysically constrained viral latency via the pheromone-controlled physiology of reproduction.
See: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964)
The synthesis of RNA in isolated thymus nuclei is ATP dependent.
See for comparison: From Fertilization to Adult Sexual Behavior
Molecular epigenetics. It is now understood that certain genes undergo a process called “genomic or parental imprinting.” Early in embryonic development attached methyl groups become removed from most genes. Several days later, methyl groups are reattached in appropriate sites. Fascinatingly, some such genes reestablish methylation patterns based upon whether the chromosomal segment carrying the gene came from maternal or paternal chromosomes. These sexually dimorphic patterns are labeled genomic or parental imprinting, and these imprintings are inheritable but non-genetic modifications of specific genes (Razin and Shemer, 1995; Reik, 1989; Surani, 1991; Zuccotti and Monk, 1995).
Imprinting is food energy-dependent and biophysically constrained by RNA-directed DNA methylation in the context of the pheromone-controlled physiology of reproduction.
See also: Species of Drosophila (1972)
Because species have distinct food and microhabitat preferences, conspecific individuals meet more often than individuals of different species. More widespread and more potent than this ecological isolation is ethological (behavioral, sexual) isolation.
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5 MIN READ
0
The Aquatic Ape / Waterside Ape divergence
6 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
Displays of ecological adaptation (2)
3 MIN READ
0
DNA repair via junk DNA (1)
5 MIN READ
0
Linking RNA structure to function
3 MIN READ
0
Exosomes, Inflammatory Disease, Pathogenesis, Treatment
< 1 MIN READ
0
How did the innate immune system evolve?
4 MIN READ
0
The Aquatic Ape: New evidence?
4 MIN READ
0
Increased soil pH and nutrient availability
4 MIN READ
0
Energy-dependent cellular communication
3 MIN READ
0
Lawless evolution: No physics
4 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Antithetical conclusions (7)
3 MIN READ
0
Antithetical conclusions (5)
4 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
RNAi: From magic bullet to billion dollar baby
4 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
Pseudoscientists ignore what serious scientists prove
6 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
The end of neo-Darwinism
5 MIN READ
0
The Origin of Information (2)
6 MIN READ
0
Funding the Human Genome Project-Write
2 MIN READ
0
Virus-driven downsizing of the human brain (2)
< 1 MIN READ
0
Virus-driven downsizing of the human brain
2 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
Masters of deception about nature (2)
7 MIN READ
0
Masters of deception about nature
8 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
Energy-dependent RNA methylation (8)
4 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (5)
3 MIN READ
0
Energy-dependent RNA methylation (3)
10 MIN READ
0
Energy-dependent RNA methylation (2)
5 MIN READ
0
Energy-dependent RNA methylation (1)
6 MIN READ
0
War Games: False Flag Terrorism
5 MIN READ
0
Virus-driven energy theft: definition?
5 MIN READ
0
Energy-dependent biodiversity (4)
4 MIN READ
0
Energy-dependent biodiversity (2)
2 MIN READ
0
Neo-Darwinism failed in 1995
3 MIN READ
0
Countdown to Genetics and Genomics
< 1 MIN READ
0
Wasted Templeton Funding (4)
3 MIN READ
0
RNA splicing, genetic variation, and disease
2 MIN READ
0
Creating and/or programming the immune system
< 1 MIN READ
0
YEC compared to Perry Marshall’s opinions
4 MIN READ
0
Creating nutrient-dependent life with enough genes to survive
3 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Jay R. Feierman: twenty years of antagonism
5 MIN READ
0
Energy dependent RNA-mediated immunity (3)
8 MIN READ
0
Science vs semantics
4 MIN READ
0
From angstroms to ecosystems and entropy
2 MIN READ
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9 MIN READ
0
Nutrient-dependent RNA-mediated cause and effect
3 MIN READ
0
Neuroscience Virtual Event vs AAAS Symposium
3 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (5)
10 MIN READ
0
The radical pair mechanism of ecological speciation
3 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Ecological genomics: teleophobes respond (too late)
10 MIN READ
0
MicroRNA-mediated RNA epigenetics
2 MIN READ
0
RNA-mediated theory killers (5)
2 MIN READ
0
RNA-mediated theory killers (2)
8 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair
2 MIN READ
0
Stress-perturbed mitochondrial dysfunction (2)
5 MIN READ
0
Understanding cell type differentiation
3 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Neuroplasticity
4 MIN READ
0
Too complex for the Complex Biological Systems Alliance
4 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
Models are not theories (2)
2 MIN READ
0
Controled Stem Cell Expansion
3 MIN READ
0
Biophysically constrained or unconstrained?
2 MIN READ
0
RNA-mediated retrotransposon-mediated biodiversity
3 MIN READ
0
Mystery machine vs model (2)
2 MIN READ
0
Energy and evolution: another opinion?
2 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Multi-omic analysis features (SNPs, miRNA)
3 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
Rs3827760 is Val370Ala and EDARV370A
3 MIN READ
0
From “Blood Music” to Evolution 2.0
5 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
Epimutation.com: a domain of confusion
8 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Riding the wrong direction
3 MIN READ
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Viruses and the human-like microbiome
3 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
From gut bacteria to breast milk and back
5 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
Graphic misrepresentations of ecological adaptation
2 MIN READ
0
Creating nothing but a theory (2)
4 MIN READ
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4 MIN READ
0
Virus-driven origin of life
2 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
Walk towards the light
< 1 MIN READ
0
What about birds?
5 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
Atheism: Arrogant, useless, and divisive ignorance
7 MIN READ
0
Military combat training to fight disease (2)
3 MIN READ
0
RNA-mediated epigenetic modification via DNA-methylation
4 MIN READ
0
Environment epigenetically shapes the immune system
3 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
0
RNA eclipses the importance of DNA to cell type differentiation
4 MIN READ
0
RNA-mediated genetic engineering (Part 2)
3 MIN READ
0
RNA-mediated genetic engineering
2 MIN READ
0
Genomic surveillance ends our world of RNA-mediated ecological adaptations
2 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Physics denied; pseudoscientific nonsense accepted
2 MIN READ
0
Quantum physics meets Evolutionary Psychology News
2 MIN READ
0
Some neuroscientists think a mutation led to human language development
< 1 MIN READ
0
Behavior: The first response is RNA-mediated not genetically-determined
3 MIN READ
0