Denying Creation via RNA-directed DNA methylation

By: James V. Kohl | Published on: November 22, 2017
Denying Creation via RNA-directed DNA methylation(click to enlarge)

Summary: Epigenetic mechanisms did not evolve.  DNA methylation is food energy-dependent and RNA-directed. Phenotypes are not fixed by genetics. The food energy-dependent RNA-directed DNA methylation of all organized genomes is biophysically constrained by the metabolism of food to pheromones, which control the physiology of food-dependent reproduction.

On the day after he posted content on the refutation of Karl Popper’s nonsense and the pseudoscientific nonsense touted in every aspect of neo-Darwinian theory, antagonist Jay Feierman posted this to the Human Ethology group:

See: Chapter 27 – Evolution of Epigenetic Mechanisms in Animals and Their Role in Speciation

DNA methylation is involved in gene regulation, silencing of transposons, imprinting, polyphenism, and consolidation of speciation. It may even act as a driver of evolution via stochastic developmental and environmentally induced epigenotype diversification, transgenerational inheritance of epigenetic patterns with phenotypic effects, and differential selection and genetic fixation of these phenotypes.

Epigenetic mechanisms did not evolve. DNA methylation is food energy-dependent and RNA-directed. Phenotypes are not fixed by genetics. The food energy-dependent RNA-directed DNA methylation of all organized genomes is biophysically constrained by the metabolism of food to pheromones, which control the physiology of food-dependent reproduction. Food and pheromones typically biophysically constrain all virus-driven pathology. That allows ecological variation to be linked to ecological adaptation via transgenerational epigenetic inheritance in species from microbes to humans.
See: RNA-directed DNA methylation: an epigenetic pathway of increasing complexity
Simply put, increasing complexity does not automagically evolve. It is biophysically constrained by what organisms eat (i.e., food energy.)See also: RNA-mediated epigenetic regulation of gene expression

Jay Feierman‘s efforts to prevent the dissemination of accurate information about biophysically constrained biologically-based food energy-dependent RNA-mediated cause and effect have led to the unnecessary suffering and premature death of millions during the past 2 decades since I personally presented to him (at a conference) the model that has since been linked to all healthy longevity in all species. (His only question was “What about birds?”)

Rarely have I seen anyone display the lack of regard for biodiversity and for human life that Jay Feierman has included in his examples of “human idiocy.” His posts about the “Evolution of Epigenetic Mechanisms” and posts about the evolution of anything else should long ago have been the “last straw” for all serious scientists. And yet, it seems that no one can stop people like Jay Feierman.

For comparison, the late Charles Manson supposedly claimed: “I am the devil.” If true, in my opinion, another devil is alive and well and his name is Jay Feierman.

Search this domain for: RNA-directed DNA methylation or for RNA-mediated DNA methylation to find hundreds of blog posts that appear to attest to the devilish treachery of people like Jay R. Feierman. If you find one blog post that does not attest to his human idiocy and his treachery, please let me know. I may owe him an apology.

See also, this Google search: RNA mediated, which attests to the facts about why this is currently the top-ranked domain.

Feierman’s other posts to the Human Ethology Group on 11/20/17 include:

Formal Epistemology and Cartesian Skepticism: In Defense of Belief in the Natural World
Eleven Telomere, Epigenetic Clock, and Biomarker-Composite Quantifications of Biological Aging: Do They Measure the Same Thing?
Give one species the task to come up with a theory that spans them all: what good can come out of that?
A soft selective sweep during rapid evolution of gentle behaviour in an Africanized honeybee
Variability in Fitness Effects Can Preclude Selection of the Fittest
Does it always pay to defend one’s nest? A case study in African penguin

Throughout the animal kingdom, individual variation in reproductive success is commonly observed, even under similar environmental conditions. However, the mechanisms behind such differences remain unclear.

The mechanisms are energy-dependent and RNA-mediated. Feierman’s “bird-brained” nonsense takes us back to this example of food energy-dependent pheromone-controlled transgenerational epigenetic inheritance of morphology and behavior in a bird species, see: Estrogen receptor α polymorphism in a species with alternative behavioral phenotypes (2014)
For a direct attack on my accurate representations, see: One crank dies, another rises to take his place
In the context of A third of Americans don’t believe in evolution, I wrote:

Ecological adaptation occurs via the epigenetic effects of nutrients on alternative splicings of pre-mRNA which result in amino acid substitutions that differentiate all cell types of all individuals of all species. The control of the differences in cell types occurs via the metabolism of the nutrients to chemical signals that control the physiology of reproduction.
These facts do not refute evolution; they simply refute the ridiculous theory of mutation-initiated natural selection that most people here were taught to believe is the theory of evolution.
That theory is far too ridiculous to be anything but a joke in the context of biological-based increasing organismal complexity. But here, we have lots of jokers, don’t we? The proof of ecological variation that appears to refute the theory of evolution, which actually refutes itself, is that ecological adaptations occur too fast for mutations to compete with them as a source of anything but diseases and disorders.

For comparison, see the comment by Jay R. Feierman on my model:

7/25/13 Jay R. Feierman:

Variation is not nutrient availability and the something that is doing the selecting is not the individual organism. A feature of an educated person is to realize what they do not know. Sadly, you don’t know that you have an incorrect understanding [of] Darwinian biological evolution.

My model was published as a refutation of neo-Darwinian evolution. Nutrient-dependent/pheromone-controlled adaptive evolution: a model

No one has ever attempted to refute Darwinian evolution. Darwin reasserted the claim that others must start with his “conditions of life.” They are nutrient-dependent and pheromone-controlled. Anyone who has ever started with natural selection is as foolish as Darwin knew they would be.

See also:  To Each His Own: Every human brain is far more unique, adaptable, and vulnerable than ever suspected.

In “Advancing Techniques Reveal the Brain’s Impressive Diversity,” Rusty Gage and two of his postdocs, Sara Linker and Tracy Bedrosian, describe nonvisual methods for delving ever deeper into neurons—analyzing not just what you see, but what you get by performing genome sequencing and transcriptional, posttranscriptional, posttranslational, and epigenetic analyses on single cells.

My comment:

The virus-driven degradation of messenger RNA has been linked to the destruction of all food energy-dependent pheromone-controlled biophysically constrained ecosystems in species from microbes to humans.
But  Researchers reveal new details on aged brain, Alzheimer’s and dementia
only recently

…revealed a surprising relationship between dementia and decreased quality of RNA—a key player in gene expression—in the more aged brain.

Obviously, something has gone horribly wrong. Serious scientists can now simply recommend that everyone older than 10 play the game Cytosis.

A board game taking place inside a human cell! Players compete to build enzymes, hormones and receptors and fend off attacking Viruses!

Anyone older than 10 can then dismiss the claims of people like Rusty Gage about ecology and simply link what organisms eat from ecological variation to ecological adaptation via the physiology of pheromone-controlled reproduction, or link the virus-driven degradation of messenger RNA from mutations to all pathology.

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2 MIN READ
1
Predictable idiosyncratic evolved convergence
3 MIN READ
0
The natural success of RNAi and failed treatment
7 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy (2)
6 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy
3 MIN READ
0
Life is energy-dependent task management (2)
3 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
Hypothesis free pseudoscience vs facts (5)
6 MIN READ
0
Hypothesis free pseudoscience vs facts (4)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (1)
5 MIN READ
0
Base pairs, olfaction and RNA thermometers
4 MIN READ
0
Chromatin: The structure of DNA (2)
8 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
DNA repair via junk DNA (2)
5 MIN READ
0
The Aquatic Ape / Waterside Ape divergence
6 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
Linking RNA structure to function
3 MIN READ
0
Protecting 4 billion people from virus-driven entropy
< 1 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Antithetical conclusions (4)
3 MIN READ
0
Anthetical conclusions (2)
5 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
GC-rich neo-Darwinian train wreck
5 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (3)
< 1 MIN READ
0
Biophysically constrained cell type differentiation
3 MIN READ
0
Virus-driven downsizing of the human brain (3)
4 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity
4 MIN READ
0
The Origin of Information (2)
6 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution
6 MIN READ
0
RNA-mediated programming of E.coli
< 1 MIN READ
0
Did “Nature” kill Steve Jobs? (2)
6 MIN READ
0
Virus-driven downsizing of the human brain (2)
< 1 MIN READ
0
RNA methylation (revisited)
< 1 MIN READ
0
Innate immunity and multiplexing
7 MIN READ
0
Amino acids and virus penetration
3 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
Model vs theory: Progress report!
8 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
Cracking the Olfactory Code?
5 MIN READ
0
RNA methylation, behavior, and disease
6 MIN READ
0
Modelling life scientifically: RNA-mediated events
12 MIN READ
0
Energy-dependent RNA methylation (8)
4 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (6)
9 MIN READ
0
Energy-dependent RNA methylation (3)
10 MIN READ
0
Energy-dependent RNA methylation (2)
5 MIN READ
0
Energy-dependent RNA methylation (1)
6 MIN READ
0
Thermotolerance and longevity (2)
3 MIN READ
0
Magic, Miracle, or Molecular Mechanism (3)
2 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
MicroRNAs and/or QTLs: Who buried what?
2 MIN READ
0
RNA splicing, genetic variation, and disease
2 MIN READ
0
From nothing to life and death everywhere
5 MIN READ
0
Molecular Diagnostics: What is unprotected life (4)
2 MIN READ
0
Molecular Diagnostics: What is unprotected life? (2)
7 MIN READ
0
Virus-driven sex differences?
2 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Virus-driven disorder prevention and health promotion
6 MIN READ
0
Jay R. Feierman: twenty years of antagonism
5 MIN READ
0
Energy dependent RNA-mediated immunity (5)
4 MIN READ
0
Science vs semantics
4 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9 MIN READ
0
Bacteria see the light and they adapt
7 MIN READ
0
The Light and Darkness of “Evolution 2.0”
11 MIN READ
0
Neuroscience Virtual Event vs AAAS Symposium
3 MIN READ
0
Despicable fools?
4 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (6)
7 MIN READ
0
The radical pair mechanism of ecological speciation
3 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs (4)
4 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
Another failed rescue attempt
5 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Ecological genomics: teleophobes respond (too late)
10 MIN READ
0
Ecological law, cooperation, and DNA repair
4 MIN READ
0
Finding peace and π in the light of H bond energy (2)
8 MIN READ
0
RNA methylation, RNA-directed DNA methylation, learning and memory
3 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Epigenetic (re)programming of behavior (3)
5 MIN READ
0
Perry Marshall: too much information for atheist PZ Myers
3 MIN READ
0
Assumptions prove ignorance (2)
5 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
Did Dobzhansky see the UV light of creation?
10 MIN READ
0
Does metabolism link beneficial mutations to cancer?
10 MIN READ
0
RNA-mediated theory killers (4)
9 MIN READ
0
Ecological adaptations you cannot live without
6 MIN READ
0
RNA-mediated regulatory mechanisms link microbes to humans (3)
5 MIN READ
0
RNA-mediated theory killers (2)
8 MIN READ
0
RNA-mediated theory killers
6 MIN READ
0
Natural cooperation and Evolution 2.0
6 MIN READ
0
A million dollar paradox?
2 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (4)
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (5)
4 MIN READ
0
Sulfated steroids and RNA-mediated identity codes
< 1 MIN READ
0
Neo-Darwinism vs the neocortex
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair
2 MIN READ
0
Life and death predicted by DNA methylation
3 MIN READ
0
Phenols: Laws of physics meet biology
2 MIN READ
0
Plasma created by sunlight and RNA–mediated epigenetic heredity
2 MIN READ
0
Behavioral Immune System model
4 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Neuroplasticity
4 MIN READ
0
Sensationalizing no new mechanism
2 MIN READ
0
Models are not theories (3)
3 MIN READ
0
Designing, engineering, and protecting biodiversity
3 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
700 million years of evolution?
5 MIN READ
0
Biophysically constrained or unconstrained?
2 MIN READ
0
RNA-mediated retrotransposon-mediated biodiversity
3 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Nutrient-dependent RNA-directed DNA methylation
5 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
Metaphysical science vs theory
4 MIN READ
0
Hijacked light energy and vertebrate pathology
4 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
A 5-10K comparison of design principles to evolution
3 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Exosomes and the RNA-mediated future of medicine
5 MIN READ
0
Somatic hypermutation vs RNA-mediated events
2 MIN READ
0
From fertilization to RNA-mediated events and back
2 MIN READ
0
Phytochemical link from the sun to cell types
2 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
The “great filter” is an epigenetic trap
4 MIN READ
0
Information and communication (2)
6 MIN READ
0
Information and communication
2 MIN READ
0
Unraveling evolutionary pseudoscience
2 MIN READ
0
From “Blood Music” to Evolution 2.0
5 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
Viruses, amino acids, and somatic cell types (3)
9 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
Big Bang Cosmology vs Reality
< 1 MIN READ
0
RNA-mediated morphological AND behavioral phenotypes
2 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Riding the wrong direction
3 MIN READ
0
Decreased phenotypic variation: Faith in Facts
7 MIN READ
1
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
Is SUMOylation RNA-directed DNA methylation? (revisited)
4 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
“Evolution” of sex differences?
2 MIN READ
0
Is SUMOylation RNA-directed DNA methylation?
2 MIN READ
0
Theorists: No rational thinking allowed
2 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Viruses and the human-like microbiome
3 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
Scientists lose. A sci-fi author gains credibility
2 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Protein isoforms do not evolve
3 MIN READ
0
Tissue type variation and expression of genes
< 1 MIN READ
0
Chance mutations — not natural selection
5 MIN READ
0
Physics, chemistry, light, and life
2 MIN READ
0
An epigenetic mark links algae, worms, and flies
2 MIN READ
0
Pathology constrains X-linked evolution
2 MIN READ
0
MicroRNAs and invasive phenotypes
< 1 MIN READ
0
Deeply ingrained thoughts
< 1 MIN READ
0
Viruses and ecologically adapted animals
2 MIN READ
0
Correctly modeling ecological adaptation
4 MIN READ
0
Behavior (4): All responses are RNA-mediated in birds
4 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
What about birds?
5 MIN READ
0
RNA directed DNA methylation and cell types
4 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
Nutritional epigenetics, exercise, and immune system integrity
4 MIN READ
0
What if Darwin was not still dead?
2 MIN READ
0
How fast can evolutionary theory be changed?
5 MIN READ
0
Sneaking up from behind (2)
3 MIN READ
0
All of "like kind" in the (bigger) family
6 MIN READ
1
Environment epigenetically shapes the immune system
3 MIN READ
0
ISHE's human ethology group
2 MIN READ
0
Jumping back: Science or Pseudoscience? (2)
2 MIN READ
0
Jumping back: Science or Pseudoscience?
6 MIN READ
0
Glycine and GnRH: Am I being pedantic?
4 MIN READ
0
Extensive molecular evidence vs ridiculous theories
2 MIN READ
0
Dual genomes: exposing the evolution industry
5 MIN READ
0
RNA-mediated events and "The Theory of Everything"
4 MIN READ
0
RNA-mediated species specificity
2 MIN READ
0
Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
0
Biologists puzzled by evolved RNAs and decaying DNA
6 MIN READ
0
Complex behaviors of cell types in cancer
6 MIN READ
0
From deep time into real time: What evolutionary processes?
10 MIN READ
0
In theory, or supported by experimental evidence?
5 MIN READ
0
It’s cell type differention, not cell fate determination (2)
3 MIN READ
0
Are evolutionary theorists 'nob ends'?
5 MIN READ
2
ALPHA GENOMIX
7 MIN READ
2
No excuses: Creation and the meaning of organismal complexity
7 MIN READ
0
No understanding of biodiversity
2 MIN READ
0
Understanding physical forces of ecological variation and adaptation
< 1 MIN READ
0
2014 and 2004 Nobel Prize in Medicine
3 MIN READ
0
RNA-mediated genetic engineering (Part 2)
3 MIN READ
0
RNA-mediated events are not a matter of faith
2 MIN READ
0
Color vision refutes the evolutionary dogma of gene duplication
4 MIN READ
0
Unassailable evidence vs assumptions
4 MIN READ
0
RNA-mediated cell type differentiation and behavior
3 MIN READ
0
Physics denied; pseudoscientific nonsense accepted
2 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Mathematical model: microRNA and epigenetic regulation
2 MIN READ
0
Quantum physics meets Evolutionary Psychology News
2 MIN READ
0
RNA-mediated species diversification from microbes to primates
3 MIN READ
0
Genotype, observed phenotype, and distinctly disordered behaviors
3 MIN READ
0
Is the problem an internet echo or Feierman's ethics?
2 MIN READ
0
Behavior (2): All responses are RNA-mediated not genetically-determined
4 MIN READ
0
Insect homology and diversity attributed to mutations
2 MIN READ
0
Behavior is receptor-mediated
10 MIN READ
0
Genes and Race: Human History?
2 MIN READ
0
Nutrition, pheromones and cancer (2)
2 MIN READ
0
Darwinian theories vs Darwin's facts
2 MIN READ
0
Jay R. Feierman
3 MIN READ
0
Pheromones and cancer
4 MIN READ
0
A flawed model: no tripartate synapse in the adult brain
3 MIN READ
0
A “new” view of evolution sans mutations
< 1 MIN READ
0
Epigenetic effects underlie sexual preferences II
3 MIN READ
0
Human pheromones determine our social behavior (REJECTED)
3 MIN READ
0
Mischaracterizations of adaptive evolution by psychologists and biologists
2 MIN READ
0
Creation of different species without physical barriers (Part One)
< 1 MIN READ
0
Did viruses make mammals communicate with pheromones?
2 MIN READ
0
Human Pheromones and The Philosophy of Science
2 MIN READ
0