Energy-dependent base editing and correction of mutations (3)
(click to enlarge)
Alzheimer’s is tractable from lactose intolerance to diverticulitis and/or colon cancer, which progresses to Alzheimer’s in some people. Others ecologically adapt via a change in diet or reduction of social stress.
Conclusion: Theories are the cause of all pathology.
Excerpts from Energy-dependent base editing and correction of mutations (2) with a primate-specific addendum
See: From Fertilization to Adult Sexual Behavior (1996)
Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegansโฆ
The alternative splicings of pre-mRNA have since been place into the context of energy-dependent changes in microRNAs (aka pre-mRNAs), which have been linked to differentiation of all cell types in all individuals of all living genera.
See: Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription
In the cytoplasm, small RNAs can control mammalian translation by regulating the stability of mRNA. In the nucleus, small RNAs can also control transcription and splicing. The mechanisms for RNA-mediated nuclear regulation are not understood and remain controversial, hindering the effective application of nuclear RNAi and investigation of its natural regulatory roles.
The tractable changes in organized genomes can be viewed in the context of The Bull Sperm MicroRNAome and the Effect of Fescue Toxicosis on Sperm MicroRNA Expression (2014)
The link to sperm selection by human ova establishes the role of quantized energy as information in the context of the physiology of reproduction, which protects all species from the virus-driven degradation of messenger RNA.ย
In mammals, this is manifested in links from what offspring ingest to their food energy-dependent pheromone-controlled survival. See for example: MicroRNAs: Milkโs epigenetic regulators
The deficiency of exosomal miRNAs in infant formula, and the persistent uptake of milk miRNAs after the nursing period are both linked from consumption of cowโs milk to epigenetic aberrations that appear to induce adverse long-term effects on human health. It seems likely that Vitamin D fortified cow’s milk does not act as advertised with the popular slogan “Got Milk?”
ADDENDUM:
The adverse effects of microRNAs in milk link the difference between lactase persistence and lactose intolerance. Lactose intolerance is caused by a deficiency of the intestinal enzyme lactase that splits lactose into two smaller sugars, glucose and galactose, and allows lactose to be absorbed from the intestine.
See also: Approximately 65 percent of the human population has a reduced ability to digest lactose after infancy. Lactose intolerance in adulthood is most prevalent in people of East Asian descent, affecting more than 90 percent of adults in some of these communities.
The obvious link from milk ingestion to the food energy-dependent de novo creation of an enzyme that is transiently required to stabilize the organized genomes of human infants should be placed into the context of Richard P. Feyman’s claim about human idiocy.
VIDEO
Do Microbes Trigger Alzheimerโs Disease?
In light of continued failures to develop effective drugs, some researchers, such as Harvard neurobiologist Rudolph Tanzi , think itโs high time that more effort and funding go into alternative theories of the disease. โAny hypothesis about Alzheimerโs disease must include amyloid plaques, tangles, inflammationโand, I believe, infection.โ
The virus-driven degradation of messenger RNA has been linked to all pathology in all living genera. The food energy-dependent pheromone-controlled physiology of reproduction has been linked to biophysically constrained viral latency and healthy longevity via transgenerational epigenetic inheritance of all morphological and behavioral phenotypes in species from microbes to humans. The structural diversity of supercoiled DNA is the manifestation of changes in base pairs that link changes in the microRNA/messenger RNA balance from RNA editing to fixation of amino acid substitutions that differentiate all cell types. The virus-driven degradation of messenger RNA prevents differentiation, which is how it is linked from infection to amyloid plaques, tangles and inflammation in all diseases.
Alzheimer’s is tractable from lactose intolerance to diverticulitis and/or colon cancer, which progresses to Alzheimer’s in some people. Others ecologically adapt via a change in diet or reduction of social stress.
Conclusion: Theories are the cause of all pathology.
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RNA-mediated regulatory mechanisms link microbes to humans (3)
5 MIN READ
0
Essential pseudoscientific concepts of atheism
3 MIN READ
0
Natural cooperation and Evolution 2.0
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (5)
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (2)
4 MIN READ
0
Teaching the biologically uninformed
3 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs
9 MIN READ
0
Neo-Darwinism vs the neocortex
4 MIN READ
0
Phenols: Laws of physics meet biology
2 MIN READ
0
Stress-perturbed mitochondrial dysfunction (2)
5 MIN READ
0
Stress-perturbed mitochondrial dysfunction
4 MIN READ
0
Let there be anti-entropic light (3)
6 MIN READ
0
Models are not theories (3)
3 MIN READ
0
Too complex for the Complex Biological Systems Alliance
4 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
Virus, transposon and plasmid evolution
< 1 MIN READ
0
MicroRNA-encoded behavior
7 MIN READ
0
Can veterans and other prisoners escape pseudoscience?
2 MIN READ
0
eQTLs and ecological adaptation
< 1 MIN READ
0
Ecological speciation. Get it, theorists?
< 1 MIN READ
0
Neo-Darwinian logic is nonsense
3 MIN READ
0
Mystery machine vs model
2 MIN READ
0
Epigenetic inheritance of stress-perturbed protein folding
2 MIN READ
0
Non-mainstream scientist shares Nobel prize in Medicine
3 MIN READ
0
Metaphysical science vs theory
4 MIN READ
0
Hijacked light energy and vertebrate pathology
4 MIN READ
0
Exosomes and the RNA-mediated future of medicine
5 MIN READ
0
From fertilization to RNA-mediated events and back
2 MIN READ
0
Genome sequencing, cadherins, and quantum consciousness
6 MIN READ
0
Thermodynamic constraints did not evolve
3 MIN READ
0
Riding the wrong direction
3 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
MicroRNA – controlled ecological adaptations
5 MIN READ
0
microRNAs and memory: Why trust a theory?
2 MIN READ
0
microRNAs, glycosylation, and genomes
4 MIN READ
0
Unknown mechanisms and conclusions
2 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Appetite for ingesting theories (raw)
< 1 MIN READ
0
Missing a fact: microRNAs are genomic biomarkers
4 MIN READ
1
Targeting theories to fight disease
2 MIN READ
0
Five years of Ferguson
2 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Protein isoforms do not evolve
3 MIN READ
0
How to find a “holy grail” under your nose
3 MIN READ
0
MicroRNAs and the exposome (2)
< 1 MIN READ
0
MicroRNAs and the exposome
5 MIN READ
0
RNA-mediated silencing of a chromosome
3 MIN READ
0
Amino acid-dependent cell type differentiation
8 MIN READ
0
Silencing genes and serious scientists
3 MIN READ
0
Nutrient-dependent microRNAs control cell types
6 MIN READ
0
MicroRNAs and memory
< 1 MIN READ
0
Viruses and ecologically adapted animals
2 MIN READ
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Anti-entropic solar energy
5 MIN READ
0
Correctly modeling biological energy
2 MIN READ
0
Questions about life’s diversity
21 MIN READ
0
UV-light mutations and gene loss (not gain)
5 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
Two types of microRNA are not double agents
2 MIN READ
0
What about birds?
5 MIN READ
0
Implicating microRNAs in cancer
2 MIN READ
0
Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs
2 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
An epigenetic trap (the prequel)
5 MIN READ
0
Nutritional epigenetics, exercise, and immune system integrity
4 MIN READ
0
The biologically-based origin of the mammalian placenta (2)
6 MIN READ
0
Are viruses microRNAs? (2)
5 MIN READ
0
Are viruses microRNAs?
3 MIN READ
0
RNA-protein interactions reveal biophysical to ecological landscapes
2 MIN READ
0
From Hydra to humans vs a Lakatosian research program
4 MIN READ
0
Dual genomes: exposing the evolution industry
5 MIN READ
0
Epigenetic pharmacology and RNA-mediated transciptional landscapes
3 MIN READ
0
More than a bag of chemicals?
2 MIN READ
0
RNA eclipses the importance of DNA to cell type differentiation
4 MIN READ
0
Pharmacogenomics
3 MIN READ
0
From deep time into real time: What evolutionary processes?
10 MIN READ
0
Itโs cell type differention, not cell fate determination (2)
3 MIN READ
0
Are evolutionary theorists 'nob ends'?
5 MIN READ
2
No understanding of biodiversity
2 MIN READ
0
Behavioral ecology: please continue to believe in our fantasies
3 MIN READ
0
Color vision refutes the evolutionary dogma of gene duplication
4 MIN READ
0
Genomic surveillance ends our world of RNA-mediated ecological adaptations
2 MIN READ
0
Systems biology and memory disorders
3 MIN READ
0
RNA-mediated cell type differentiation and behavior
3 MIN READ
0
Metabolism, fixation, health or neurodegerative disorder
2 MIN READ
0
Genotype, observed phenotype, and distinctly disordered behaviors
3 MIN READ
0
RNA-mediated ecological adaptation is not evolution
2 MIN READ
0
Exploding genomes and chromosomal rearrangements via RNA-mediated events
2 MIN READ
0
Behavior (2): All responses are RNA-mediated not genetically-determined
4 MIN READ
0
A relatively young branch of science called epigenetics
4 MIN READ
0
Baby talk: More misrepresentations of ecological adaptations
2 MIN READ
0
Comparing divergent model organisms
2 MIN READ
1
Order and disorder: Ecological adaptations not mutations
6 MIN READ
0
microRNAs and species relationships
3 MIN READ
0
Cell-type differentiation
2 MIN READ
0
The wrong picture of our evolution
4 MIN READ
0
96 fixed amino acid substitutions, not 96 genes
6 MIN READ
0
Alternative splicings (very technical)
2 MIN READ
0
Pheromone-controlled thermodynamics and cancer
2 MIN READ
0
Alzheimer's, microRNAs, and olfaction
< 1 MIN READ
0
Pheromones and cancer
4 MIN READ
0
Sex differences in Alzheimer's and everything else
2 MIN READ
0
Diet epigenetically effects development of the primate brain
< 1 MIN READ
0
The Epigenetics of Drug Development and Cholesterol Levels
< 1 MIN READ
0
Bee research, human sweet perception, human pheromones, and metabolic disorders
< 1 MIN READ
0
Epigenetics of food odors, nutrition, and pheromones
< 1 MIN READ
0