From base editing to RNA editing (8)

By: James V. Kohl | Published on: December 28, 2017

(click to enlarge)

Excerpt:

See: Quantum Vacuum Dynamics, Coherence, Superluminal Photons and Hypercomputation in Brain Microtubules

Finally, these theorists attempt to link the speed of light on contact with water (Darwin’s “conditions of life”) to all biophysically constrained biodiversity.

Researchers find potential path to repair multiple sclerosis-damaged nerves December 26, 2017

Multiple sclerosis is an autoimmune, neurodegenerative disease, characterized by distinct disabilities affecting walking, vision, and cognition, to name a few. MS patients differ markedly from each other regarding which disability affects them the most. Inflammation strips the myelin coating from nerve cell extensions, called axons, and connections at the ends of nerves, called synapses, are lost, together disrupting signaling and eventually causing permanent disability depending on where this occurs.

See: microRNA multiple sclerosis
The virus-driven theft of quantized energy has been linked from the degradation of messenger RNA to the inflammation and all pathology. Food energy has been linked to error-free DNA repair of virus-driven damage to organized genomes and pheromone-controlled ecological adaptations in all living genera.
For a historical perspective see:

Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer’s disease (2013)

Nutrient-dependent/pheromone-controlled adaptive evolution: a model (2013)

Yesterday, I brought my model current in this blog post: From nitrogen atoms to ecosystems in all living genera December 27, 2017
See also:

Helpful intestinal bacteria counteracts tendency to depression December 27, 2017

The rats that did not receive probiotics had an increased number of white blood cells in their brain tissue, which can be a sign of chronic inflammation, and is also seen in the fatty tissues and livers of overweight people and diabetics. The researchers did not find the elevated amounts of white blood cells in the brains of the rats with probiotics in their drinking water. “This may indicate that one of the things the probiotics do is work to reprogramme the immune system.

“The Kreb’s cycle or tricarboxylic acid cycle, which takes place in the mitochondria, is the fundamental pathway that generates cellular energy and, recently, mutations in genes that produce key metabolites have been implicated in neurodegeneration and cancer,” said first author Berrak Ugur, a graduate student in the Bellen lab.

For comparison, see: Deep Reads: How I learnt to love population genetics December 21, 2017
It is difficult to understand why anyone would want to make claims about population genetics, since virtually all prior claims have been debunked or dismissed by serious scientists.
Here is an exception:

Role of the Visual Experience-Dependent Nascent Proteome in Neuronal Plasticity December 27, 2017

…de novo synthesis of machinery that regulates RNA splicing and protein translation is required for experience-dependent plasticity.

The magic of de novo synthesis can be linked to population genetics since there is no need for quantized energy or for biophysical constraints on viral latency. The proteome is “nascent” and experience-dependent leaning is somehow linked from visual input to the functional structure of supercoiled DNA and all pheromone-controlled biodiversity in species from microbes to humans.
Nascent definition: “beginning to exist or develop” (aka automagical creation)
Outside the context of automagical creation, creationists have resurrected their claims from this past summer, as if no scientific progress had been made.

#8 of Our Top Stories of 2017: Theorist Concedes, Evolution “Avoids” Questions December 25, 2017

They ignore the fact that the cell biology game “Cytosis” is available to teach anyone 10+ years of age how to protect their organized genome from the virus-driven degradation of messenger RNA that links mutations to all pathology.
It seems clear that they want to keep the evolutionary time frame but abandon all evolutionary processes. But, they also seem to think that makes sense — or that it may make sense to others who are biologically uninformed theorists.
This makes sense. Biological wires carry electricity thanks to special amino acids March 12, 2013
Passive/Aggressive antagonist, Jon Lieff, mentioned this on December 26, 2017: Many more bacteria have electrically conducting filaments December 8, 2017
See for comparison to what is known about physically constrained energy: Biogenic non-crystalline U(IV) revealed as major component in uranium ore deposits
This was reported in the context of biophysically constrained energy.
See: Biologists discover electric bacteria that eat pure electrons rather than sugar, redefining the tenacity of life July 18, 2014

“This is huge. What it means is that there’s a whole part of the microbial world that we don’t know about.”

The ability of bacteria to eat electrons, reproduce, and to create uranium isotopes could be linked from quantized energy as information to all biodiversity on Earth via the physiology of pheromone-controlled reproduction, if pseudoscientists would acknowledge the facts about the food energy-dependent fixation of amino acid substitutions.

Simply put, amino acid substitutions protect all organized genomes from the virus-driven degradation of messenger RNA. That fact clearly refutes all claims that have ever been made by neo-Darwinian theorists who must now place their claims into the context of ecological variation and species-specific cell type specific ecological adaptations.
See also: Electrically conductive pili from pilin genes of phylogenetically diverse microorganisms September 5, 2017
Reported December 8, 2017 as: Many more bacteria have electrically conducting filaments

In recent years, the UMass Amherst microbiologists and physicists working with Geobacter species developed a hypothesis for how its e-pili are able to conduct electric current based on the presence of aromatic amino acids in the pilin subunits. They have used this characteristic — a high density of aromatic amino acids and a lack of substantial aromatic-free gaps along pilin chains — to select candidate pili genes from other microorganisms, including many difficult-to-culture microorganisms.

If their hypothesis includes any aspect of what others have reported in the context of ridiculous neo-Darwinian theories, they may report that the aromatic amino acids in the pilin subunits created themselves and then evolved into the food energy-dependent pheromone-controlled amino acid substitutions that stabilize the organized genomes of all living genera.
It is that level of nonsense that has been replaced with facts and the facts are included in new theories. It is time for the neo-Darwinists to admit that none of their ridiculous claims were supported by experimental evidence of biologically-based cause and effect. The levels of complexity that must now be examined make the nonsense touted by neo-Darwinists irrelevant.
See: Quantum Vacuum Dynamics, Coherence, Superluminal Photons and Hypercomputation in Brain Microtubules
Finally, these theorists attempt to link the speed of light on contact with water (Darwin’s “conditions of life”) to all biophysically constrained biodiversity.

…a confined field of faster than light photons field of suitable wavelength can arises from a spontaneous phase transition of the QED quantum vacuum occurring in the water contained inside the microtubules inner volume. It has been shown that, in the water trapped inside microtubules, there exist the conditions for the formation of a macroscopic coherent quantum state…

The interaction between water and ions is omnipresent in biological processes related to enzymes, ion channels and protein folding. Every new piece of knowledge gives greater insight into how life works.

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From base editing to RNA editing (8)

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