Enzyme-constrained interethnic biodiversity (3)

By: James V. Kohl | Published on: January 9, 2018

Excerpt: Understanding a “correlational mechanism” is like understanding mutation-driven evolution. You have a mutation. You have evolution. Thus, you understand the simple-minded magic of the correlation. No energy-dependent molecular mechanisms are required.
For comparison: Enzyme-constrained interethnic biodiversity is exemplified in Amish populations in the United States of America. Obviously, interethnic difference in genes matter.
See: Low cancer incidence rates in Ohio Amish (2009) Why Don’t The Amish Get Cancer? (2016)
See also: A null mutation in SERPINE1 protects against biological aging in humans (2017)
Reported as: An Internal Fountain of Youth: Why These Amish Live Longer And Healthier

Amish with this mutation also have significantly less diabetes and lower fasting insulin levels.

“The findings astonished us because of the consistency of the anti-aging benefits across multiple body systems,” said Dr. Douglas Vaughan, the lead author of the paper who has been studying PAI-1 for almost 30 years.

See also: Diabetes and Alzheimer’s correlation mechanism understood!
Understanding a “correlational mechanism” is like understanding mutation-driven evolution. You have a mutation. You have evolution. Thus, you understand the simple-minded magic of the correlation. No energy-dependent molecular mechanisms are required.
For comparison, see: Aerobic Glycolysis in the Human Brain Is Associated with Development and Neotenous Gene Expression
The article links imaging to the required molecular mechanisms of behavioral development. Finally,  all serious scientists can move forward as they should have been doing for more than a decade since Panksepp et al (2002) published Comparative approaches in evolutionary psychology: molecular neuroscience meets the mind. His group won the same award that my group won for publication in 2001 of: Human pheromones: integrating neuroendocrinology and ethology.
Comparative approaches start with the creation of quantized energy and link it to aerobic glycolysis. Clearly, all serious scientists have been following the experimental evidence that led to publication of: Redefining neuroendocrinology: Epigenetics of brain-body communication over the life course (November 15, 2017) by Bruce McEwen and Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology (November 24, 2017), which was co-authored by Bruce McEwen.
Brain-body communication is food energy-dependent. The obvious link from the virus-driven degradation of messenger RNA to mutations and all pathology via gene losses has since led to the end of the hunt for drugs to treat some neurodegenerative diseases. See Enzyme-constrained interethnic biodiversity (6)
Unfortunately, even though Bruce McEwen set the stage for achieving world peace in the context of interethnic biodiversity, he did not win the 2017 Nobel Peace Prize as I predicted he would.
See: Predicting who wins the 2017 Nobel Prizes

Bruce McEwen has since helped others to link nutrient-stress and social stress from the virus-driven degradation of messenger RNA to amino acid substitutions in the context of the physiology of pheromone-controlled reproduction. For example, the substitution of one amino acid in the cell types of mammals protects them from the virus-driven energy theft that links amino acid substitutions in viruses to all pathology. McEwen’s works are the only known works of a serious scientist who has continued to refute the pseudoscientific nonsense touted by neo-Darwinian theorists since before 1964.

Indeed, most people who are not yet dead, probably do not know how people like Bruce McEwen have linked food energy-dependent “Interethnic Genetic Similarities and Differences” to world peace.
But see: Living in a Genetic World: How Learning About Interethnic Genetic Similarities and Differences Affects Peace and Conflict
Reported as: For groups in conflict, genes matter 

“In conflict contexts, we often see attempts to emphasize genetic differences between groups. We saw that in Rwanda. We saw that in Bosnia,” Kimel said. “One thing we suggest in the paper is that groups like International Crisis Watch and Genocide Watch should go on heightened alert when they see this kind of rhetoric in conflict contexts.”

The paper also cites popular media reports on the genetic differences between groups with a history of conflict. Such articles are cause for concern, Kimel said, because they often fail to mention just how genetically similar humans are.

The similarities in all humans have been linked to interethnic differences in only two genes via publication of Brief report: Geographic variation in EGFR mutation frequency in lung adenocarcinoma may be explained by interethnic genetic variation. I reiterate: The full article can be downloaded from :


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