Enzyme-constrained interethnic biodiversity (6)
(click to enlarge)
See: Celgene Near Acquisition of Impact Biomedicines
Chief Executive Officer Mark Alles has pledged to look outside Celgene’s own labs for new drugs to bolster its pipeline, telling investors in October that “we look for opportunity all the time.”
The CEOs of companies like this have been looking in all the wrong places for several decades. All of “Big Pharma” is dangerously close to collapse under the weight of evidence known to serious scientists who have linked physics and chemistry to the conserved molecular mechanisms of biophysically constrained RNA-mediated cell type differentiation that protect all living genera from the virus-driven degradation of messenger RNA.
The CEOs don’t want you to be freaked out by the price tag for medications that will bankrupt the economy of the United States of America. But, quite frankly, this freaks me out.
See also: An $850,000 Price Tag on Gene Therapy Shouldn’t Freak You Out—Yet
Spark’s Luxturna was approved by the U.S. Food and Drug Administration in December for patients who have a genetic mutation in the RPE65 gene, which causes degenerative retinal disease.
The therapy, which is injected into the eye, contains millions of engineered virus particles containing correct copies of the gene. The treatment improves vision but doesn’t fully restore it.
The real test may come when Spark and other companies start winning approval to sell gene-replacement therapies for diseases like hemophilia and sickle-cell anemia, which affect tens of thousands of people in the U.S.
Spark’s inadvertently appears to claim gene-replacement therapies can prevent the virus-driven theft of messenger RNA that causes the mutation in the RPE65 gene. If so, the food energy-dependent pheromone-controlled hemoglobin S ecological adaptation will require treatment with enzymes or food supplements that increase the production of specific enzymes.
That might be the most effective treatment. However, sooner or later, people will learn that sickle-cell anemia is a food energy-dependent ecological adaptation that can be linked from one base pair change and one amino acid substitution to all other pathology. “Big Pharma” will then no longer control the economic success of the United States of America.
Indeed, this publication may drive the decline of the gene-editing component of the stock market: Identification of Pre-Existing Adaptive Immunity to Cas9 Proteins in Humans
Pre-Existing Adaptive Immunity in Humans is RNA-mediated. The facts about interethnic variation in hemoglobin molecules link pre-existing humoral and cell-mediated adaptive immune responses from Cas9 to the RNA-mediated factors that must be taken into account before the CRISPR-Cas9 system moves forward into clinical trials. The CRISPR-Cas9 system damage to human DNA caused by gene editing could be prevented by something as relatively simple as enrolling more participants in studies like this one: Nevada Health Project Participants to Gain Access to Helix Genomics Marketplace
See for comparison: Exome Sequencing Data Links ADCY3 to Severe Obesity
Loss-of-function mutations in ADCY3 cause severe obesity, according to a series of new studies in Nature Genetics.
Exome sequencing yields much more data than genotyping does and the data conclusively shows that there is no such thing as a gain-of-function mutation. That is why food energy-dependent changes in SNPs have consistently been linked to interethnic biodiversity and to differences in longevity in modern human populations like the Amish.
See also: Pfizer Ends Hunt for Drugs to Treat Alzheimer’s and Parkinson’s by Jonathan.Rockoff@wsj.com
The end of the hunt links Bruce McEwen’s works to the beginning of the search for effective treatments that must help to biophysically constrain viral latency if they are used to treat some neurodegenerative diseases.
Bruce McEwen’s works, link energy-dependent cell type differentiation from feedback loops that link olfaction to the pheromone-controlled physiology of reproduction.
Historical perspective: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” McEwen et al., (1964)
The synthesis of RNA in isolated thymus nuclei is ATP dependent.
For a practical application of facts that McEwen’s life’s works have detailed since 1964, see:
Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis
The fact that human pheromones biophysically constrain the pathology of neurodegenerative diseases has been known to all serious scientists since the time that this was published in 1994.
Pheromonal regulation of genetic processes: research on the house mouse (Mus musculus L.)
The conserved molecular mechanisms of RNA-mediated cell type differentiation have not changed since the dawn of the energy-dependent creation of ATP and RNA.
That fact was indirectly represented in New Description of the Rostral Migratory Stream in Adult Mice Brains Delineating the Starter of the Stream as an Infundibulum: A New Described Limb, by H&E and Antidoublecortin Antibody
Conclusion: The neuroblasts take different arrangement through their period of life from their site of origin to their final destination the olfactory bulb through the RMS.
The creation of the neuroblasts and their energy-dependent niche construction in the olfactory bulb is tractable to the niche creation of bacteria, which neo-Darwinian theorists seem to think occurs in the context of the evolution of functional structures such as the flagellum via a “quantum leap.”
See: Biologists Trace Evolution of Bacterial Flagellar Motors
This clear separation between primitive and sophisticated species represents a ‘quantum leap’ in evolution…
That claim represents a return to de Vries definition of mutation, which Schrodinger (1944) placed into the context of his organized thoughts about biophysically constrained biodiversity with my emphasis.
“…about forty years ago [in1902] the Dutchman de Vries discovered that… a very small number of individuals, say two or three in tens of thousands, turn up with small but ‘jump-like’ changes, the expression ‘jump-like’ not meaning that the change is so very considerable, but that there is a discontinuity inasmuch as there are no intermediate forms between the unchanged and the few changed. De Vries called that a mutation. The significant fact is the discontinuity. It reminds a physicist of quantum theory -no intermediate energies occurring between two neighbouring energy levels. He would be inclined to call de Vries’s mutation theory, figuratively, the quantum theory of biology. We shall see later that this is much more than figurative. The mutations are actually due to quantum jumps in the gene molecule.
See for comparison: Evolution of higher torque in Campylobacter-type bacterial flagellar motors (January 8, 2018)
Phylogenetic inference was made using maximum-likelihood in GARLI (v2.01.1067)23, using Jones, Taylor and Thornton (JTT) amino acid substitution rates24.
Phylogenetic inferences still seem to be based on a definition of mutation from 1902. For comparison, all serious scientists have learned that the food energy-dependent pheromone-controlled physiology of reproduction links the fixation of RNA-mediated amino acid substitutions in the cell types of all individuals of all species from biophysically constrained viral latency to all biodiversity in all living genera.
I have placed the proof of concept for my model into a series of blog posts on “Interethnic Diversity” in an attempt to help biologically uninformed theorists join serious scientists from the 21st century who are Combating Evolution to Fight Disease
Recruits are required to take intelligence tests and compete basic training with an essay on top-down causation that links the sun’s anti-entropic virucidal energy from the physiology of reproduction to all biodiversity on Earth without mention of mutation or evolution.
Recommended reading includes a monograph from Bruce McEwen about his life’s works, and one recently published work that was co-authored by Bruce McEwen:
See: Redefining neuroendocrinology: Epigenetics of brain-body communication over the life course
The details of natural biological rhythms; “allostatic overload” (as a natural part of autophagy and limits on population density);
a natural molecule acetyl-L-carnitine (LAC); our natural day-night rhythm; and natural cycles of protein biosynthesis and degradation are linked from a naturalistic rodent model to interethnic biodiversity. There is no mention of natural selection and only one mention of evolution and one mention of mutation.
See also: Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology
RNA interference links base editing from microRNA editing to the energy-dependent fixation of RNA-mediated amino acid substitutions that differentiate all cell types in all individuals of all living genera.
Bruce McEwen’s works and his advice: “Start with gene activation (in GnRH neurosecretory neurons)” led to publication of our 1996 Hormones and Behavior review of RNA-mediated cell type differentiation. We linked food energy to the pheromone-controlled physiology of reproduction and all biodiversity in species from yeasts to primates via alternative splicing of pre-mRNA.
From Fertilization to Adult Sexual Behavior
Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegans… That similar proteins perform functions in humans suggests the possibility that some human sex differences may arise from alternative splicings of otherwise identical genes.
The fact that sex differences do not evolve has since been linked to all the other differences in cell types that did not evolve. The National Microbiome Initiative has been linked to the Precision Medicine Initiative and to refutations of all the pseudoscientific nonsense that has been touted by theorists during the past few decades of stalled scientific progress.
See for another example. Epigenetic supersimilarity of monozygotic twin pairs
…we identified genomic regions at which the epigenetic similarity of monozygotic twins is substantially greater than can be explained by their genetic identity. This “epigenetic supersimilarity” apparently results from locus-specific establishment of epigenotype prior to embryo cleavage during twinning. Epigenetically supersimilar loci exhibit systemic interindividual epigenetic variation and plasticity to periconceptional environment and are enriched in sub-telomeric regions. In case-control studies nested in a prospective cohort, blood DNA methylation at these loci years before diagnosis is associated with risk of developing several types of cancer.
Reported as: Identical twins can share more than identical genes: Molecular similarity
For decades, researchers have studied genetically identical twins to estimate what proportion of disease risk is determined by one’s genes. To the extent that epigenetic supersimilarity affects risk of disease, as our results indicate, genetic risk estimates based on twin studies have been inflated.
This is how sex researchers stalled scientific progress. They failed to recognize that all molecular similarities and differences are food energy-dependent and the transgenerational epigenetic inheritance of all similarities and differences must be links from the physiology of pheromone-controlled reproduction to the energy-dependent biodiversity that is displayed in all life on Earth.
Public health bodies such as the CDC are mandated to meet the needs of all people, in all their diversity.
All diversity is food energy-dependent and biophysically constrained in the context of the pheromone-controlled physiology of reproduction, which links autophagy to viral latency. The Trump administration is clearly making an attempt to ensure that the CDC does not obfuscate the language used by serious scientists. Serious scientists know how to link physics and chemistry from molecular epigenetics to biophysically constrained viral latency by one or more RNA-mediated amino acid substitutions. The amino acid substitutions are consistently referred to as mutations in examples of human idiocy:
See: Brief report: Geographic variation in EGFR mutation frequency in lung adenocarcinoma may be explained by interethnic genetic variation The full article can be downloaded from here: https://bit.ly/2z97l9b
EDAR V370A and ABCC11 G180A are the two energy-dependent RNA-mediated amino acid substitutions that the authors refer to as mutations, which they link to interethnic genetic variation in the context of de Vries 1902 definition of mutation and A Civic Biology: Presented in Problems (1914).
pp. 195-196
Evolution of Man. – Undoubtedly there once lived upon the earth races of men who were much lower in their mental organization than the present inhabitants. If we follow the early history of man upon the earth, we find that at first he must have been little better than one of the lower animals.
p. 263
If such people were lower animals, we would probably kill them off to prevent them from spreading. Humanity will not allow this, but we do have the remedy of separating the sexes in asylums or other places and in various ways preventing intermarriage and the possibilities of perpetuating such a low and degenerate race. Remedies of this sort have been tried successfully in Europe and are now meeting with success in this country.
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Evolution outside the context of “the light of evolution”
6 MIN READ
0
Sexual communication signals: New Insights!
10 MIN READ
0
Host-derived creation of all pathology (2 of 2)
9 MIN READ
0
Host-derived creation of all pathology (1 of 2)
5 MIN READ
0
God vs host-derived creation of virus-driven pathology (2)
4 MIN READ
0
God vs host-derived creation of virus-driven pathology
6 MIN READ
0
Stem cells do not create themselves
3 MIN READ
0
Energy and neural plasticity
< 1 MIN READ
0
Your indifference is killing you and others
5 MIN READ
0
Your indifference is killing you and others (3)
4 MIN READ
0
Robert Sapolsky’s legacy of atheistic pseudoscientific nonsense
4 MIN READ
0
Automagical protein creation sans energy
9 MIN READ
0
Sunlight, phytochemicals, microRNAs and cancer
5 MIN READ
0
Solar analemma with a total solar eclipse
2 MIN READ
0
The Origin of Information (4)
4 MIN READ
0
Can protein folding chemistry be understood by theorists?
5 MIN READ
0
Evolutionary congruence (losers) vs ecological adaptation (winners)
3 MIN READ
0
Pattern recognition vs evolutionary processes (revisited)
7 MIN READ
0
New Testament Book Cover Refutes Theistic Evolution
7 MIN READ
0
Energy-dependent physical and biophysical constraints (9)
3 MIN READ
0
Energy-dependent physical and biophysical constraints (7)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (5)
7 MIN READ
0
Energy-dependent physical and biophysical constraints (4)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (3)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (1)
5 MIN READ
0
Epigenetic effects of stress by Bruce McEwen (2)
3 MIN READ
0
Epigenetic effects of stress by Bruce McEwen (1)
9 MIN READ
1
God’s shrinking role in salvation (3)
9 MIN READ
0
God's shrinking role in salvation (3)
9 MIN READ
0
MicroRNAs GnRH and the failure of sex research
7 MIN READ
0
God’s shrinking role in salvation (2)
5 MIN READ
0
God’s shrinking role in salvation
8 MIN READ
0
Food energy-dependent cell type differentiation (2)
10 MIN READ
0
Hard Science vs the neo-Darwinian “magic box”
9 MIN READ
0
Infections and age change the odor of wine and people
4 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models (5)
5 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models (4)
2 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models (2)
6 MIN READ
0
Food energy-dependent epigenetic adaptation (3)
3 MIN READ
0
Food energy-dependent epigenetic adaptation (2)
< 1 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (5)
4 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (4)
2 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (3)
5 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (2)
5 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability
8 MIN READ
0
Nothing evolved into all biodiversity on Earth
4 MIN READ
0
Energy as information and constrained endogenous RNA interference (4)
7 MIN READ
0
What energy source do proteins prefer?
6 MIN READ
0
Energy-dependent microRNA biogenesis
4 MIN READ
0
Draining the academic swamp of parasites
3 MIN READ
0
The death of CRISPR; long live endogenous RNAi
5 MIN READ
0
Virus-driven downsizing of the human brain (4)
2 MIN READ
0
What is life without sunshine?
2 MIN READ
0
Viruses in pathogenic variants disrupt alternative splicings (2)
3 MIN READ
0
Epigenetically-effected nucleosome repositioning sheds Dobzhansky’s light on evolution
3 MIN READ
0
Synthetic RNA-based switches
2 MIN READ
0
Sunlight bursts the social bubble of physics and math
3 MIN READ
0
Functionally interdependent editing and methylation
4 MIN READ
0
Cytosis: Biology Content
7 MIN READ
0
Light-activated feedback loops vs self-organization of ecosystems
7 MIN READ
0
Cytosis: A Cell Biology Board Game
< 1 MIN READ
0
Sal Giardina: apologetics revisited
8 MIN READ
0
Life in your UV light-constrained galaxy
5 MIN READ
0
Who will kill the billion dollar baby? Bill Gates or Donald Trump
3 MIN READ
0
Thinking about energy is not radical re-thinking
6 MIN READ
0
Energy-dependent pheromone-controlled entropy (4)
3 MIN READ
0
The essence of precision medicine: drug targets or healthy longevity?
4 MIN READ
0
Allen Institute confirms food energy is information
6 MIN READ
0
RNA-mediated adult learning, memory, and neurogenesis
3 MIN READ
0
Energy-dependent allelic imbalances, viruses, and pathology
3 MIN READ
0
Theistic evolutionists fight back and lose (3)
4 MIN READ
0
Theistic evolutionists fight back and lose
4 MIN READ
0
Young earth creationists refute theistic evolution
3 MIN READ
0
Bill Gates refutes theistic evolution (prequel)
2 MIN READ
0
Bill Gates refutes theistic evolution (sequel)
8 MIN READ
0
Bill Gates refutes theistic evolution
4 MIN READ
0
Emily Witkin refutes theistic evolution
2 MIN READ
0
Wikipedia refutes theistic evolution
4 MIN READ
0
RNA editing refutes theistic evolution
4 MIN READ
0
Serious scientists refute theistic evolution again
3 MIN READ
0
Pseudoscientists fail to refute theistic evolution
4 MIN READ
0
Stuart Kauffman refutes theistic evolution
3 MIN READ
0
May the anti-entropic force of sunlight be with you
4 MIN READ
0
Francis S. Collins refutes theistic evolution
6 MIN READ
0
Energy is information. Objections over ruled. You’re fired!
7 MIN READ
0
Happy Darwin Day (2017)
4 MIN READ
0
George Church refutes theistic evolution (3)
5 MIN READ
0
George Church refutes theistic evolution (2)
2 MIN READ
0
Natural selection for codon optimality and quantum viruses
5 MIN READ
0
Physicists: Desperate Acts (revisited)
6 MIN READ
0
Energy as information and constrained endogenous RNA interference (3)
4 MIN READ
0
Energy as information and constrained endogenous RNA interference (2)
2 MIN READ
0
Virus-driven energy theft and premature death
3 MIN READ
0
Fighting for virus-driven pathology
5 MIN READ
0
ATP-dependent creation of RNA
2 MIN READ
0
Dobzhansky 1973 and precision medicine (5)
3 MIN READ
0
Dobzhansky 1973 and Precision Medicine (2)
5 MIN READ
0
Another failed attempt to address the malaria challenge
2 MIN READ
0
Dobzhansky 1973 and precision medicine
6 MIN READ
0
Twisted theories and weaponized facts
3 MIN READ
0
Autophagy: from pre-mRNAs to microRNAs, enhancers, QTLs et al.
6 MIN READ
0
Chirality, nutritional epigenetics, autophagy, and ethnicity
< 1 MIN READ
0
Mutations: the “driving force” behind human brain complexity?
6 MIN READ
0
Mutations: the "driving force" behind human brain complexity?
6 MIN READ
0
Science journalists or paid propagandists? (3)
6 MIN READ
0
Critical values expose virus-driven energy theft (2)
4 MIN READ
0
Theorists sell hidden energy (2)
4 MIN READ
0
Critical values expose virus-driven energy theft
6 MIN READ
0
Theorists sell hidden energy
3 MIN READ
0
Anti-entropic energy and the “Music of Life”
3 MIN READ
0
Anti-entropic energy and the "Music of Life"
3 MIN READ
0
Evolved patterns of brain stimulation
3 MIN READ
0
Chirality is reality
6 MIN READ
0
Energy-dependent chirality (2)
3 MIN READ
0
Energy-dependent chirality
6 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5 MIN READ
0
Vietnam Veterans and others with glioblastoma
3 MIN READ
0
Energy-dependent sensory maps (1996-2016)
5 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016
12 MIN READ
0
Energy-dependent oscillating gene networks organize life
4 MIN READ
0
2016 obfuscated facts about energy as information
5 MIN READ
0
More refutations of neo-Darwinian nonsense
7 MIN READ
0
Re-inventing mutation-driven evolution (2)
4 MIN READ
0
Sudden death indel polymorphism
4 MIN READ
0
Bio-functional information
3 MIN READ
0
Energy-dependent self-organization and self repair
8 MIN READ
0
Expunging the distinguished public
2 MIN READ
0
Explorers who do not know what is known (2)
6 MIN READ
0
Explorers who do not know what is known
4 MIN READ
0
Energy-dependent natural translational selection
4 MIN READ
0
Autophagy is the antiphage defense strategy
3 MIN READ
0
Energy-dependent de novo creation and neurogenesis (2)
5 MIN READ
0
Energy-dependent de novo creation and neurogenesis
7 MIN READ
0
Theories vs facts about polycombic adaptation
3 MIN READ
0
Tasting light links energy from creation to adaptation
9 MIN READ
0
Politicized science: The demise of RNA-mediated.com?
3 MIN READ
0
Combating evolution: Battlefield medicine vs politicized science
6 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Metabolic Phenotyping Research
2 MIN READ
0
Phylogenetic similarity sans energy
2 MIN READ
0
De novo gene creation: Ignoring the experimental evidence
7 MIN READ
0
Energy-dependent coulombic, autophagic, polycombic healthy longevity
4 MIN READ
0
Light, behavior and autophagy, a gender-specific risk factor
4 MIN READ
0
Controlled amino acid treatment of all pathology
4 MIN READ
0
Energy-dependent purifying selection / autophagy (2)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (3)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (4)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (5)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (6)
3 MIN READ
0
Energy-dependent purifying selection / autophagy
2 MIN READ
0
Optogenetics: Let there be virucidal light!
2 MIN READ
0
Theorists struggle with the concept of autophagy
2 MIN READ
0
Base pairs, amino acids and phenotypes
10 MIN READ
0
Survivors of RNA-mediated terrorism
5 MIN READ
0
Building delicious base pairs in class. It’s elementary Watson and Crick
3 MIN READ
0
Building delicious base pairs in class. It's elementary Watson and Crick
3 MIN READ
0
RNA-mediated “repurposing” is autophagy
2 MIN READ
0
RNA-mediated "repurposing" is autophagy
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (8)
4 MIN READ
0
Epigenetically effected energy-dependent fluorescence
5 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (7)
3 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (4)
< 1 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (3)
< 1 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (2)
2 MIN READ
0
From precis to pre-mRNA and proof of concept in F1, F2, F3
6 MIN READ
0
From Precis to Proof in 6000 years
9 MIN READ
0
Coulombic interactions facilitate polycombic adaptation
5 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
Polycombic ecological adaptation as a science, not a theory
3 MIN READ
0
Attacking Young Earth Creationists
5 MIN READ
0
80 years of causal analysis (1936 – 2016)
11 MIN READ
0
Predictable idiosyncratic evolved convergence
3 MIN READ
0
Carl Woese was wrong
2 MIN READ
0
The natural success of RNAi and failed treatment
7 MIN READ
0
Pheromone-controlled autophagy
4 MIN READ
0
Hecatombic evolution via oncocers and oncohistones
9 MIN READ
0
Did evolution autophosphorylate your kinases? (2)
5 MIN READ
1
Did evolution autophosphorylate your kinases?
5 MIN READ
1
Nutrient-dependent autophagy
3 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy (2)
6 MIN READ
0
The last RNA-mediated theory killer (2)
7 MIN READ
0
Asking the right questions (2)
3 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy
3 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
Hypothesis free pseudoscience vs facts (5)
6 MIN READ
0
Hypothesis free pseudoscience vs facts (4)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (1)
5 MIN READ
0
Base pairs, olfaction and RNA thermometers
4 MIN READ
0
Chromatin: The structure of DNA (2)
8 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
DNA repair via junk DNA (2)
5 MIN READ
0
The Aquatic Ape / Waterside Ape divergence
6 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
Displays of ecological adaptation (2)
3 MIN READ
0
Unconstrained mutations, Zika virus, Kallmann’s syndrome
4 MIN READ
0
The Aquatic Ape: New evidence?
4 MIN READ
0
Energy-dependent cellular communication
3 MIN READ
0
Lawless evolution: No physics
4 MIN READ
0
Antithetical conclusions (7)
3 MIN READ
0
Antithetical conclusions (5)
4 MIN READ
0
Antithetical conclusions (6)
3 MIN READ
0
RNAi: From magic bullet to billion dollar baby
4 MIN READ
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
0
GC-rich neo-Darwinian train wreck
5 MIN READ
0
From angstroms to ecosystems
7 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
The end of neo-Darwinism
5 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity
4 MIN READ
0
The tipping point? 50,000 publications (5)
3 MIN READ
0
RNA-mediated programming of E.coli
< 1 MIN READ
0
Did “Nature” kill Steve Jobs? (2)
6 MIN READ
0
RNA methylation (revisited)
< 1 MIN READ
0
Placing boundaries where none exist
< 1 MIN READ
0
MicroRNAs and sexual orientation
8 MIN READ
0
Innate immunity and multiplexing
7 MIN READ
0
Amino acids and virus penetration
3 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
Model vs theory: Progress report!
8 MIN READ
0
Masters of deception about nature (2)
7 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
Cracking the Olfactory Code?
5 MIN READ
0
RNA methylation, behavior, and disease
6 MIN READ
0
Energy-dependent RNA methylation (9)
2 MIN READ
0
Energy-dependent RNA methylation (6)
9 MIN READ
0
Energy-dependent RNA methylation (5)
3 MIN READ
0
Energy-dependent RNA methylation (2)
5 MIN READ
0
Secular humanism and ecoterrorism
4 MIN READ
0
War Games: False Flag Terrorism
5 MIN READ
0
The tipping point? 50, 000 publications (2)
2 MIN READ
0
The tipping point? 50, 000 publications
4 MIN READ
0
Magic, Miracle, or Molecular Mechanism (2)
8 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
Wasted Templeton Funding (4)
3 MIN READ
0
From nothing to life and death everywhere
5 MIN READ
0
Magic, Miracle, or Molecular Mechanism?
10 MIN READ
0
Molecular Diagnostics: What is unprotected life (3)
5 MIN READ
0
Molecular Diagnostics: What is unprotected life? (2)
7 MIN READ
0
Molecular Diagnostics: What is unprotected life?
2 MIN READ
0
Virus-driven sex differences?
2 MIN READ
0
Ricki Lewis’ Time Machine (4)
8 MIN READ
0
Creating and/or programming the immune system
< 1 MIN READ
0
Nutrient-dependent life vs virus-driven pathology
4 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Jay R. Feierman: twenty years of antagonism
5 MIN READ
0
Energy dependent RNA-mediated immunity (6)
5 MIN READ
0
Energy dependent RNA-mediated immunity (4)
6 MIN READ
0
Energy-dependent RNA-mediated immunity (1)
10 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9 MIN READ
0
Despicable fools?
4 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
The radical pair mechanism of ecological speciation
3 MIN READ
0
Center stage RNA-mediated events (since 1996)
3 MIN READ
0
Juvenile hormone links atoms to ecosystems
3 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
Amino acid substitutions, stress, and human behavior
3 MIN READ
0
RNA-mediated theory killers (11) (12) (13) (14) (15)
7 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Epigenetic (re)programming of behavior (3)
5 MIN READ
0
Epigenetic (re)programming of behavior (2)
6 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
NORAD: air defense and defense against genomic entropy
7 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs
9 MIN READ
0
Stress-perturbed mitochondrial dysfunction
4 MIN READ
0
Models are not theories (2)
2 MIN READ
0
Fossils vs cell types and the brain
3 MIN READ
0
Neo-Darwinian logic is nonsense
3 MIN READ
0
Human pheromone deniers: What’s next?
5 MIN READ
0
Virucidal effects on ecological speciation
5 MIN READ
0
Microbes to humans 2015 Nobel Prize
2 MIN READ
0
Metaphysical science vs theory
4 MIN READ
0
The bug in the “holy grail” of evolution
4 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Hijacked light energy and vertebrate pathology
4 MIN READ
0
New anti-entropic microbes
3 MIN READ
0
Natural selection: an anti-entropic force?
2 MIN READ
0
Information and communication (2)
6 MIN READ
0
Ecological speciation vs revised evolutionary syntheses
6 MIN READ
0
Viruses, amino acids, and somatic cell types
4 MIN READ
0
Hematopoiesis and practopoiesis
4 MIN READ
0
The pseudoscientific nonsense of behaviorists
< 1 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
An unprecedented view of genomic complexity
2 MIN READ
0
Amino acid substitutions are not mutations
2 MIN READ
0
“First” evidence
5 MIN READ
0
RNA-mediated development
2 MIN READ
0
Rejecting pseudoscientific nonsense
6 MIN READ
1
Living the life that randomness created? (Sarcasm alert)
3 MIN READ
0
Missing a fact: microRNAs are genomic biomarkers
4 MIN READ
1
Scientists lose. A sci-fi author gains credibility
2 MIN READ
0
Targeting theories to fight disease
2 MIN READ
0
Protein isoforms do not evolve
3 MIN READ
0
MicroRNAs and the exposome (2)
< 1 MIN READ
0
MicroRNAs and the exposome
5 MIN READ
0
Finding odor and taste receptors everywhere
6 MIN READ
0
Nutrient-dependent RNA interference
4 MIN READ
0
A genetic variant refutes neo-Darwinism
6 MIN READ
0
Nutrient-dependent microRNAs control cell types
6 MIN READ
0
Behavior (4): All responses are RNA-mediated in birds
4 MIN READ
0
UV-light mutations and gene loss (not gain)
5 MIN READ
0
Epigenetics Skeptism
5 MIN READ
0
Reverse phosphorylation
7 MIN READ
0
RNA-mediated repurposing in microbes and adaptations in primate brains
2 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
A single amino acid substitution differentiates cell types of E. coli
3 MIN READ
0
RNA-protein interactions reveal biophysical to ecological landscapes
2 MIN READ
0
Removing natural selection; reshaping the horse; adjusting evolutionary theory
4 MIN READ
0
Jumping back: Science or Pseudoscience?
6 MIN READ
0
Extensive molecular evidence vs ridiculous theories
2 MIN READ
0
Are mutations beneficial?
4 MIN READ
0
Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
0
Intelligent viruses and cancers?
10 MIN READ
0
We need pattern recognition, not a prologue
6 MIN READ
0
Are evolutionary theorists 'nob ends'?
5 MIN READ
2
ALPHA GENOMIX
7 MIN READ
2
No excuses: Creation and the meaning of organismal complexity
7 MIN READ
0
Nutrient-dependent gene duplication in plants (but not animals?)
4 MIN READ
0
Evolutionary theorists justify fear of the Ebola viruses
2 MIN READ
0
Evolutionary theorists and evolutionary theists live under rocks
< 1 MIN READ
0
2014 and 2004 Nobel Prize in Medicine
3 MIN READ
0
RNA-mediated events are not a matter of faith
2 MIN READ
0
Color vision refutes the evolutionary dogma of gene duplication
4 MIN READ
0
Genomic surveillance ends our world of RNA-mediated ecological adaptations
2 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Physics denied; pseudoscientific nonsense accepted
2 MIN READ
0
Ecological variation and niche construction: 1, 2, 3
6 MIN READ
0
Epigenetically-effected metabolic shifts and ecological adaptations
3 MIN READ
0
Stop evolutionary theorists. Kill cancers
3 MIN READ
0
Did our adapted mind evolve?
6 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Do bacterial proteins evolve?
3 MIN READ
0
Probable changes in connectivity
2 MIN READ
0
Memory of repression and memory of behavior (2)
< 1 MIN READ
0
Nutrient-dependent pheromone-controlled exercise-induced physiques
< 1 MIN READ
0
RNA-mediated species diversification from microbes to primates
3 MIN READ
0
RNA-mediated events found everywhere
2 MIN READ
0
Some neuroscientists think a mutation led to human language development
< 1 MIN READ
0
Is the problem an internet echo or Feierman's ethics?
2 MIN READ
0
Mechanisms that are not understood increase clarity
4 MIN READ
2
Evolutionary heritage or ecological adaptation? Racism versus reality
4 MIN READ
0
Biophysically constrained beginnings of RNA and DNA
4 MIN READ
0
Epimutations: Attacking pseudoscientific dogmas
4 MIN READ
0
Genes and Race: Human History?
2 MIN READ
0
MiRNAs methylation and ecological adaptation sans mutations
2 MIN READ
0
Darwinian theories vs Darwin's facts
2 MIN READ
0
Targeting a cancer gene
2 MIN READ
0
Social experiences epigenetically effect gene networks
2 MIN READ
0
Pheromone-controlled thermodynamics and cancer
2 MIN READ
0
Evolution: innovations may have non-adaptive origins (sans mutations)
2 MIN READ
0
Epigenetic effects underlie sexual preferences III
3 MIN READ
0
Natural selection and the behavior of whole organisms
< 1 MIN READ
0
Natural selection: New insights are unlikely
< 1 MIN READ
0
Human pheromones and IQ via neurogenic and socio-cognitive niche construction
2 MIN READ
0
Human pheromones, nutrition, DNA, epigenetics
2 MIN READ
0
Epigentics and the baby connectome
2 MIN READ
0
Epigenetics and the connectome
2 MIN READ
0
Behavioral epigenetics
2 MIN READ
0
Genes, Hormones, and Behavior (for other scientists)
4 MIN READ
0
Epigenetics, science fiction, and scientific fact
2 MIN READ
0
Presentation on Human Pheromones delivered on August 3, 2010
2 MIN READ
0