Enzyme-constrained interethnic diversity (7)

By: James V. Kohl | Published on: January 15, 2018

Summary:  I suspect that John Hewitt will soon publish an article on the energy-dependent creation of microRNAs and enzymes. He is most likely to link the virus-driven theft of quantized energy as information to all pathology without challenging pseudoscientists and other science journalists to revise their ridiculous claims about mutation-driven evolution.
Digital medicine, on its way to being just plain medicine

There are already nearly 30,000 peer-reviewed English-language scientific journals, producing an estimated 2.5 million articles a year.

Until recently, no published works linked the creation of the sun’s anti-entropic virucidal energy from ATP to the creation of RNA and biophysically constrained viral latency.
But see: EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation January 15, 2018

“Loss of EXD2 results in defective mitochondrial translation, impaired respiration, reduced ATP production…” and “…aberrant association of messenger RNAs with the mitochondrial ribosome.

Exonuclease 3′ –5′ domain-containing 2 (EXD2) is a mitochondrial ribonuclease. A ribonuclease is a type of nuclease that catalyzes the degradation of RNA into smaller components such as microRNAs. A nuclease is an enzyme capable of cleaving the phosphodiester bonds between monomers of nucleic acids. EXD2 is required for mitoribosome integrity and efficient mitochondrial translation.
See: The Excitable Mitochondria by John Hewitt, who brought the article on EXD2 to my attention in his tweets. The link from energy-dependent changes in EXD2 to homeostasis predicts the link from reduced ATP production to the virus-driven degradation of EXD2 to the aberrant associations that link mutations in messenger RNA to all pathology. I suspect that John Hewitt will soon publish an article on the energy-dependent creation of microRNAs and enzymes. He is most likely to link the virus-driven theft of quantized energy as information to all pathology without challenging pseudoscientists and other science journalists to revise their ridiculous claims about mutation-driven evolution. Challenging your peers leads to your elimination from consideration. Your peers cannot rise to the ocassion and meet the challenge, so they must ignore you.
As I finalize this series on enzyme-constrained interethnic diversity, I also offer information from my largely ignored FB posts on the anniversary dates indicated:
January 10, 2017

The scent of eros: mysteries of odor in human sexuality

“This is science at its best, with adventure, ideas, and lots of facts”. — Helen Fisher

“A treasure hunt through history, literature, and scientific data”. — Gina Ogden

On pages 160-162 of “The Scent of Eros” (1995/2002) we linked race and ethnicity to all biodiversity via the same model of biologically-based cause and effect. It is still the only valid model.

What exactly do people think was still being debated about the fact that all organisms must eat to reproduce, or that pheromones control the physiology of reproduction in all living genera?

How could race and ethnicity not be aspects of a valid model of biologically-based cause and effect unless pseudoscientists convinced you to believe in mutation-driven evolution?

January 10, 2016

This serves as a reminder to all sex researchers. Most of them understand nothing about how RNA-mediated sex differences in cell types are linked to sex differences in #behavior by nutrient-dependent amino acid substitutions.
They refused to accept the fact that the pheromone-controlled physiology of reproduction and chromosomal rearrangements link the molecular epigenetics of cell type differentiation in all cell types of all individuals of all species from microbes to humans.

Xistential crisis: Discovery shows there’s more to the story in silencing X chromosomes
Xist is widely believed to be both necessary and sufficient for X silencing,” … “We for the first time show that it’s not sufficient, that there have to be other factors, on the X-chromosome itself, that activate Xist and then cooperate with Xist RNA to silence the X-chromosome.
An example of how 20 years of ignorance about RNA-mediated cell type differentiation leads to “NEW” discoveries.
From Fertilization to Adult Sexual Behavior 1996
Genomic-imprinting is also manifest in specific parts of the X-inactivation region’s related XIST gene. Here male- and female-specific methyl-group patterns participate in X-inactivation in females and also in the preferential inactivation of the paternal X in human placentae of female concepti (Harrison, 1989; Monk, 1995). This process indicates that tissues of the early conceptus can sense and react differentially to epigenetic sexual dimorphisms on the female conceptus’ own two X chromosomes. Furthermore, variations of X-inactivation patterns often account for traits discordance in monozygotic twin females. In other words, they are often found to have nonidentical patterns of X-inactivation, yielding differing expression of noticeable X-linked traits (Machin, 1996).
January 10, 2017

The anniversary of an attack on science.

Odious Christianity
Ray Comfort

Professor PZ Myers hates Christianity. Nor is he a big fan of my good friend, Ken Ham.
In writing about his hatred, PZ unwittingly showed his hand when he said,

“I reject his notion of sin — the idea that there is some kind of divine law against which we can transgress — but humanists do not deny that we can do wrong and we can do harm. We think we should do better, not to appease some vengeful deity, but because it improves our lives and helps make those around us happier and better able to live up to their potential. We certainly do accept that death is inevitable, but not because we are wicked — the wicked often seem to flourish while the good may die young. Are we to measure the virtue of human beings by their longevity? Charles Manson is 82, and surely destined to join the saints in heaven, while every infant death must open a chute directly to hell for its wicked soul.”
His hatred is perfectly in line with the Bible:
“Because the carnal mind is enmity against God; for it is not subject to the law of God, nor indeed can be” (Romans 8:7).
PZ is unashamedly godless (a state the Bible refers to as “carnal”), and so his mind is at “enmity” against God. That means he is in a continual state of hostility towards his Creator. That certainly is true. Even though he doesn’t believe that He exists, but he contemptuously hates the very thought of “a god.”
But look at the pinpoint accuracy of the Scriptures:
“…for it [our carnal mind] is not subject to the law of God, nor indeed can be.”
His hatred is directed at the “law of God,”–the moral Law (the Ten Commandments).
PZ is like a criminal who hates the police, not because of who they are individually, but because of what they represent. They stand for the law–that which is right and good, and that is offensive to someone who loves and lives for crime.
PZ’s railings about his loved ones dying is tragic, but peripheral. They are not the main reason why he is angry.
His anger is primarily at God and His Law, because he doesn’t like being told what to do. Like you and I before we came to Christ, he loves his sin, and he who loves the darkness hates the light.
I’m not sure why PZ called Charles Manson “wicked,” when his atheistic worldview doesn’t allow for anyone to be “wicked.”
Or could it simply be that Manson transgressed the moral Law, which says “You shall not kill,” and PZ intuitively knows that, because of his God-given knowledge of right and wrong (see Romans 2:15).
It’s actually heartening to see him using his moral compass. If he would put down his weapons and study how God’s moral compass is infinitely higher, he may rethink his rejection of “The soul who sins, shall die.”
This is because every death is sobering evidence of the truth of that verse.
You can see PZ in action in our movie “Evolution vs God” (over 2 million views) at www.FullyFreeFilms.com
P.S. PZ hates the movie.

January 10, 2017

How Your Toxic Boss Is Hurting Your Mental Health

Get out before the DNA damage is irreparable.

I do not have a boss. But the stress of attempting to interest others in what is known about how biologically-based cause and effect must be linked to interethnic similarities and differences may prevent some further attempts to explain how DNA damage is biophysically constrained in the context of naturally occurring RNA interference and viral latency.
November 27, 2017 See: Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks
Reported on November 29, 2017 as: RNA takes over control of DNA break repair

Now, a study shows that following the formation of DNA double-strand breaks, bidirectional transcription events adjacent to the break generate small RNAs that trigger the DNA damage response by local RNA:RNA interactions.

The RNA:RNA interactions are energy-dependent and they link the creation of microRNAs to the creation of enzymes, receptors, and hormones that protect organized genomes from virus-driven energy theft and all pathology.  But they are not just RNA:RNA interactions. The interactions among microRNAs and messenger RNA link food energy and the pheromone-controlled physiology of reproduction to all biodiversity on Earth without the pseudoscientific nonsense touted by biologically uninformed theorists and science journalists such as Ed Yong and Carl Zimmer.


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