The eternal significance of microRNAs (1) – revisited
(click to enlarge)
I have never been forced to revisit a blog post on the day after it was posted, until now. The Scientist has misrepresented everything known to all serious scientists about the eternal significance of microRNAs in:
Sweet Tooth Gene Tied to Less Body Fat
“These results suggest that FGF21 has pleiotropic effects, with separate effects on macronutrient intake to those on body shape and blood pressure,” the authors write in their report.
My comment to The Scientist
See All About that Base (Meghan Trainor Parody) 12/10/14 from the Zechiedrich lab and their 2015 published work: Structural diversity of supercoiled DNA
A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure is an open access publication.
The authors link one food energy-dependent change in a base pair from rs838133, which is an A/G/T single-nucleotide variation on human chromosome 19, to biophysically constrained viral latency and healthy longevity in the mouse-primate-human model of pheromone-controlled reproduction.
In that model, and in all model organisms feedback loops link what organisms eat to all morphological and behavioral diversity. See: Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems
The atoms to ecosystems model of sympatric speciation refutes neo-Darwinian pseudoscentific nonsense by linking rs3827760, also known as 1540T/C, 370A, V370A, or Val370Ala, from a SNP in the ectodysplasin A receptor EDAR gene on chromosome 2 to conserved morphological and behavioral phenotypes in mice and humans.
My past comments to The Scientist may be removed before others can see how my 500+ comments have continued to attest to the facts about sympatric speciation since the time that Eugene Garfield posted his comment about “The Scent of Eros: Mysteries of Odor in Human Sexuality. See “Scent of a Book Deal” (1995)
We made a deal with the editor at Continuum Publishing to include an attestation to mutations and evolution. I mentioned that to the late Eugene Garfield at the time I met with him in Minot, ND during a conference he funded in its entirety. His friend William Turner and I were among the few people who knew that Gene was present. He kept a low profile so that he could listen and learn.
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0
The Mind’s Eyes (revisited)
10 MIN READ
0
Cracking the Olfactory Code?
5 MIN READ
0
RNA methylation, behavior, and disease
6 MIN READ
0
Energy-dependent RNA methylation (10)
4 MIN READ
0
Energy-dependent RNA methylation (8)
4 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (6)
9 MIN READ
0
Energy-dependent RNA methylation (5)
3 MIN READ
0
Energy-dependent RNA methylation (3)
10 MIN READ
0
Energy-dependent RNA methylation (2)
5 MIN READ
0
Energy-dependent RNA methylation (1)
6 MIN READ
0
Secular humanism and ecoterrorism
4 MIN READ
0
War Games: False Flag Terrorism
5 MIN READ
0
Energy-dependent biodiversity (3)
7 MIN READ
0
Energy-dependent biodiversity (2)
2 MIN READ
0
The tipping point? 50,000 publications (3)
6 MIN READ
0
The tipping point? 50, 000 publications (2)
2 MIN READ
0
Neo-Darwinism failed in 1995
3 MIN READ
0
Countdown to Genetics and Genomics
< 1 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
RNA splicing, genetic variation, and disease
2 MIN READ
0
Wasted Templeton Funding (3)
2 MIN READ
0
Wasted Templeton Funding (2)
2 MIN READ
0
Millions of water molecules vs years of evolution
2 MIN READ
0
A bumper crop of virus-infected weeds and people
2 MIN READ
0
Molecular Diagnostics: What is unprotected life (4)
2 MIN READ
0
Molecular Diagnostics: What is unprotected life (3)
5 MIN READ
0
Molecular Microbial Ecology
8 MIN READ
0
Molecular Diagnostics: What is unprotected life? (2)
7 MIN READ
0
Molecular Diagnostics: What is unprotected life?
2 MIN READ
0
Ricki Lewis’ Time Machine (4)
8 MIN READ
0
Creating and/or programming the immune system
< 1 MIN READ
0
Half truths support theories without facts
4 MIN READ
0
Ricki Lewis’ Time Machine (3)
5 MIN READ
0
Creating nutrient-dependent life with enough genes to survive
3 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Virus-driven disorder prevention and health promotion
6 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Do not miss the misrepresentations
2 MIN READ
0
Energy dependent RNA-mediated immunity (3)
8 MIN READ
0
RNA-mediated DNA modifications
5 MIN READ
0
Science vs semantics
4 MIN READ
0
From angstroms to ecosystems and entropy
2 MIN READ
0
Bacteria see the light and they adapt (2)
5 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
0
Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA
2 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (7)
5 MIN READ
0
Organic Compounds and the Miracle of Smell and Taste
7 MIN READ
0
Neuroscience Virtual Event vs AAAS Symposium
3 MIN READ
0
Cancer: Evolution 2.0’s Blind Spot
13 MIN READ
0
Ricki Lewis’ Time Machine (2)
6 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
Juvenile hormone links atoms to ecosystems
3 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Ecological genomics: teleophobes respond (too late)
10 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
Amino acid substitutions, stress, and human behavior
3 MIN READ
0
RNA methylation, RNA-directed DNA methylation, learning and memory
3 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Assumptions prove ignorance (2)
5 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
Assumptions prove ignorance
5 MIN READ
0
Neo-Darwinian sink testing
2 MIN READ
0
NORAD: air defense and defense against genomic entropy
7 MIN READ
0
Life history transitions and RNA-mediated survial
2 MIN READ
0
Did Dobzhansky see the UV light of creation?
10 MIN READ
0
RNA-mediated theory killers (6) (7) (8) (9) (10)
5 MIN READ
0
Manufacturing fossil “evidence”
4 MIN READ
0
RNA-mediated theory killers (4)
9 MIN READ
0
RNA-mediated theory killers (5)
2 MIN READ
0
RNA-mediated theory killers (3)
7 MIN READ
0
RNA-mediated theory killers
6 MIN READ
0
Natural cooperation and Evolution 2.0
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
0
Organization of biological sequences
2 MIN READ
0
Virally derived RNA molecules and cell types
2 MIN READ
0
Positive feedback loops and epigenetic traps
2 MIN READ
0
Stress-perturbed mitochondrial dysfunction (2)
5 MIN READ
0
Behavioral Immune System model
4 MIN READ
0
Stress-perturbed mitochondrial dysfunction
4 MIN READ
0
Sensationalizing no new mechanism
2 MIN READ
0
Too complex for the Complex Biological Systems Alliance
4 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
Virus, transposon and plasmid evolution
< 1 MIN READ
0
Conserved molecular mechanisms
< 1 MIN READ
0
Models are not theories (2)
2 MIN READ
0
Models are not theories (1)
2 MIN READ
0
Can veterans and other prisoners escape pseudoscience?
2 MIN READ
0
Unraveling the secrets of RNA-mediated events
2 MIN READ
0
Ecological speciation. Get it, theorists?
< 1 MIN READ
0
Designing, engineering, and protecting biodiversity
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Neo-Darwinian logic is nonsense
3 MIN READ
0
FREE* SAMPLE: Histone modification
4 MIN READ
0
Biophysically constrained or unconstrained?
2 MIN READ
0
Mutated mitochondrial genes vs Supercoiled DNA
2 MIN READ
0
Mystery machine vs medical intelligence
2 MIN READ
0
Molecule of life vs animal experiments
< 1 MIN READ
0
Keep the gay gene theory?
< 1 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Information and communication (2)
6 MIN READ
0
Unraveling evolutionary pseudoscience
2 MIN READ
0
Rs3827760 is Val370Ala and EDARV370A
3 MIN READ
0
Viruses, amino acids, and somatic cell types
4 MIN READ
0
Ignoring top-down causation
2 MIN READ
0
MicroRNAs and the exposome
5 MIN READ
0
RNA-mediated silencing of a chromosome
3 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
Methylation maintains cell type differences
3 MIN READ
0
2 genes in 2 species (too expensive and too insignificant)
11 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Mimicking claims and ignoring facts
4 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
What if Darwin was not still dead?
2 MIN READ
0
Military combat training to fight disease (2)
3 MIN READ
0
From Hydra to humans vs a Lakatosian research program
4 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
Chemical ecology and RNA-mediated control of DNA loops
< 1 MIN READ
0
Jumping back: Science or Pseudoscience? (2)
2 MIN READ
0
Extensive molecular evidence vs ridiculous theories
2 MIN READ
0
Meaningful dialogue, anonymous fools and idiot minions
4 MIN READ
0
Sackler Colloquium: Effects or AFFECTS on Behavior
2 MIN READ
0
Systems biology and memory disorders
3 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
microRNAs differentiate neuronal cell types
3 MIN READ
0
