The origin of information (5,4,3,2,1)

By: James V. Kohl | Published on: May 21, 2018

Summary: These findings reveal a new GLU biosynthetic pathway, which could contribute to some of the sunlight-induced neurobehavioral changes.
The claims about new biosynthetic pathways should be placed into the context of what is known about the energy-dependent origin of all pathways.
Researchers may have solved origin-of-life conundrum

…the conditions that produce nucleic acid precursors also create the starting materials needed to make natural amino acids and lipids. That suggests a single set of [light activated] reactions could have given rise to most of life’s building blocks simultaneously.

Moderate UV Exposure Enhances Learning and Memory by Promoting a Novel Glutamate Biosynthetic Pathway in the Brain

All UV-induced metabolic, electrophysiological, and behavioral effects could be reproduced by the intravenous injection of UCA and diminished by the application of inhibitor or short hairpin RNA (shRNA) against urocanase, an enzyme critical for the conversion of UCA to GLU. These findings reveal a new GLU biosynthetic pathway, which could contribute to some of the sunlight-induced neurobehavioral changes.

Reported 5/17/18 as: Could a Dose of Sunshine Make You Smarter?

Urocanic acid can absorb UV rays and, as a result, may be able to protect skin against the sun’s harmful effects. But in the liver and other peripheral tissues, the acid is also known to be an intermediate molecule generated in the metabolic pathway that converts histidine to glutamate. Given glutamate’s role in the brain as an excitatory neurotransmitter, Xiong and his colleagues were interested to test whether the observed UV-dependent increase in urocanic acid in neurons might be coupled with increased glutamate production.

cis-urocanic acid biophysically constrains UV light. The quantized energy-dependent creation of urocanic acid links light-activated endogenous substrates in all cell types of all living genera to viral latency.
The creation of sunlight has been linked from the creation of ATP synthase, the creation of ATP, and the creation of RNA to prevention of the virus-driven degradation of messenger RNA at every level of examination. The virus-driven degradation of messenger RNA links changes in pH from mutations to all pathology.
See: pH Gradient Reversal: An Emerging Hallmark of Cancers
pH is the potential of hydrogen, which is altered by the virus-driven energy theft of quantized information. See also the effects linked from changes in pH to the creation of microRNAs and glutamate.
glutamate + microRNA
See for comparison: The energy expansions of evolution (4/28/17)

  1. The history of the life–Earth system can be divided into five ‘energetic’ epochs, each featuring the evolution of life forms that can exploit a new source of energy. These sources are: geochemical energy, sunlight, oxygen, flesh and fire. The first two were present at the start…
  2. Viruses, however, are likely to have been an important force from early in the history of life31. They act as agents of death—and by lysing cells, they would have provided additional sources of organic carbon to heterotrophs. Viruses also transport genes from one host to another, and thus may have enabled the spread of evolutionary innovations.
  3. …the likely development of a life–planet system will depend on the interplay between the planet’s cosmic situation, its intrinsic properties, and the paths that evolving life can potentially take. The example of this life–planet system suggests that the development of a flourishing, complex biosphere depends on a virtuous circle between evolving life forms and transformations of their planetary home.

Life forms do not evolve. They adapt in the context of nutrient-dependent pheromone-controlled physiology of reproduction.
See: Feedback loops link odor and pheromone signaling with reproduction
All serious scientists have linked the creation of the sun’s anti-entropic virucidal energy from the origin of information to healthy longevity via feedback loops. All biologically uninformed science idiot continue to tout the pseudoscientific nonsense of their ridiculous theories.
For comparison, see:
The origin of information (4) 8/4/17
The origin of information (3) 8/3/17
The origin of information (2) 7/28/16
The origin of information (1) 7/28/16

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