MicroRNA-mediated alternative splicing (revisited)

By: James V. Kohl | Published on: June 7, 2018

Building one molecule from a reservoir of two atoms reported as: Cold chemistry with two atoms.
They linked differences in the energy of photons from two different wavelengths of light, 700 nm and 976 nm, to the creation of the molecule NaCs*. They were able to detect molecule formation in the context of atom loss and NaCs* vibrational levels near the dissociation threshold. Detecting resonances that have not been previously observed appears to be the link from quantum physics to quantum chemistry and the link from quantum biology to quantum souls.
A PubMed search for “microRNA” returns more than 73,000 additional works that typically use the current term. MicroRNAs (formerly known as pre-mRNAs) are linked from the quantized energy-dependent creation of all biodiversity via the physiology of pheromone-controlled reproduction, which is manifested in the morphological and in the behavioral phenotypes of all living genera.
See for contrast: RNA components of the spliceosome regulate tissue- and cancer-specific alternative splicing

…we systematically tested the hypothesis that endogenous variation in snRNA [small nuclear RNAs] levels confers regulatory capacity on these RNAs.

The creation of sunlight links the creation of endogenous substrates to the creation of the RNA components that these authors claim regulates tissue- and cancer-specific alternative splicing.  The light-activated endogenous substrates must be placed into the context of food energy-dependent pheromone-controlled biophysical constrained viral latency to bring their representations of top-down causation into compliance with the extant literature used to support “The Science Behind the Game” (for ages 10+) “Cytosis
The cell biology game links the quantized energy-dependent creation of ATP to the microRNA-mediated alternative splicings, which these researchers place into the context of pre-mRNAs. (Pre-mRNAs are now also called microRNAs.)
See: microRNA-mediated regulation of splicing factors SRSF1, SRSF2 and hnRNP A1 in context of their alternatively spliced 3’UTRs
See also: Systematic evaluation of isoform function in literature reports of alternative splicing

My tweet (May 23, 2018) : Our 1996 Hormones and Behavior review, we linked food energy-dependent microRNA-mediated alternative splicings to all biodiversity via the physiology of reproduction.

See also: RNA components of the spliceosome regulate tissue- and cancer-specific alternative splicing
My Tweet: (June 7, 2018)

RNA components of the spliceosome regulate tissue- and cancer-specific alternative splicing https://www.biorxiv.org/content/early/2018/05/21/326983 “… endogenous variation in snRNA [small nuclear RNAs] levels confers regulatory capacity on these RNAs.” They link microRNAs to viral latency and all biodiversity.

The readily perceived problem with preprints posted to to the Cold Springs Harbor Laboratory biology preprint server Biorxiv is the underlying history of ignorance manifested in misrepresentations of scientific creationism like this: Nature’s masterpiece: the brain

A major contributor to what we know so far about life science is Jim Watson, who just turned 90 years old. He and his wife, Liz, have been devoted to CSHL for 50 of those years. In 1953, when Jim was only 24, his explanation of the structure of DNA was touted as the discovery of the secret of life. Even he could not have envisioned how much has been revealed since. I hope you find the advances described herein inspiring.

Very few serious scientists accepted the claims of James Watson. Most seem to have realized that the link from the creation of the sun’s anti-entropic energy is the secret of life.
See: What is Life? with the forward by Roger Penrose who co-authored with George F.R. Ellis and Stephen Hawking. Penrose wrote on (8 August 1991):

How often do we still hear that quantum effects can have little relevance in the study of biology, or even that we eat food in order to gain energy?

For a historical perspective on the lack of scientific progress that can be directly attributed to ridiculous representations of the energy-independent static DNA double helix (i.e., outside the context of what is known about quantized energy-dependent supercoiled DNA), see our section on molecular epigenetics in From Fertilization to Adult Sexual Behavior (1996)

Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegans (Adler and Hajduk, 1994; de Bono, Zarkower, and Hodgkin, 1995; Ge, Zuo, and Manley, 1991; Green, 1991; Parkhurst and Meneely, 1994; Wilkins, 1995; Wolfner, 1988). That similar proteins perform functions in humans suggests the possibility that some human sex differences may arise from alternative splicings of otherwise identical genes.

To move forward see: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems (2018) and wait for presentations during Schrödinger at 75 – The Future of Biology – September 2018. 
In the same month, the scheduled release of the game “Subatomic” will help others age 10+ to bring their ridiculous theories current via the use of terms that link quantum physics to quantum biology.
Other tweets: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems
See for comparison: “…photodetectors capture the light created when a neutrino interacts with an atomic nucleus.” Apparently, the light that was captured by the photodetectors created itself via the interaction.
If the captured light did not create itself via the interaction, it makes sense to watch as these speakers link quantized energy (i.e., sunlight) to the creation of microRNAs and messenger RNAs, which biophysically constrain viral latency.
RegenDbase: a comparative database of noncoding RNA regulation of tissue regeneration circuits across multiple taxa. 
“… a systems-level analysis of tissue regeneration genetic circuits across injury and animal models and addresses the growing need to understand how noncoding RNAs influence these changes in gene expression.”
What don’t you understand about quantized energy-dependent RNA-mediated changes in gene expression? See: What is Life? (1944)  “…we eat food in order to gain energy?” – Roger Penrose (1991)
Luca Turin wrote
This explanation of the Laplace Transform by Steven Smith https://www.dspguide.com/ch32.htm is so… transcendentally good that it makes you feel maybe even quantum field theory would be as clear as day if this particular genius put his mind to it.
My reply: What isn’t clear? See: Building one molecule from a reservoir of two atoms Signaling is quantized energy-dependent and biophysically constrained by the physiology of reproduction in the context of olfaction and pheromones at this level of examination…
Add: …and every other level of examination.

Notify of
Inline Feedbacks
View all comments

Want more on the same topic?

Swipe/Drag Left and Right To Browse Related Posts: