MicroRNA-mediated feedback loops (3)
(click to enlarge)DNA Methylation: Timekeeper of Biological Age
Cellular senescence, telomere shortening, and changes in gene expression have been well documented to contribute to the aging process. Recently, researchers have found that epigenetic changes, such as the presence of methyl groups in close proximity to CpG dinucleotides located near a gene’s promoter, correlate with age. Technological advances, including microarray analysis and next-generation sequencing, have clarified the relationship between DNA methylation and aging, to the point that such phenomena may even be used to predict one’s chronological age. For a detailed look at the biology of human aging and the dynamics of DNA methylation, The Scientist is bringing together a panel of experts to share their research, to discuss how the epigenome influences aging, and to highlight the approaches scientists are taking to study the possibility of targeting epigenetic modifications for therapeutic intervention. Attendees will learn how the epigenome controls aging from renowned experts in our interactive setting.
Yesterday was the last good day any theorist ever had.
DNA methylation is quantized energy-dependent and RNA-mediated. That means the creation of the sun has now been linked from microRNA biogenesis to the physiology of pheromone-controlled reproduction and biophysically constrained viral latency.
Unless something goes wrong, viral latency ensures healthy longevity. Most people make choices that ensure the onset of virus-driven pathology in the context of the degradation of their messenger RNA.
Most people do not know that naturally occurring RNA interference repairs the virus-driven damage to DNA via RNA-directed DNA methylation.
Most people do not know that because pseudoscientists will not tell them the truth.Besides, when the truth is told, most people will not listen. They will suffer unnecessarily and die prematurely for that reason, and only that reason.
The theme of this tweet and this blog post is “Don’t be like most people.”
Most people will ignore the MicroRNA-mediated feedback loops theme