Creating an enzyme that kills theories (2)

By: James V. Kohl | Published on: October 15, 2018

Summary: These authors linked differences in the energy of two photons to the creation of enzymes and all biophysically constrained biodiversity. They do not seem to know what they did.

Unfortunately, it may not be possible to stop the Democrats from continuing to allow others to tout pseudoscientific nonsense until after the mid-term elections, in which case we may all join the Republicans and the Democrats who have died in the context of my series on War Games: False Flag Terrorism.
The War Games pit ridiculous theories against facts, like this.
Segregated encoding of spatiotemporal features in the mouse visual cortex

…provide novel insights… that might underpin distinct visual computations, such as motion and shape processing.

Visual computations are energy-dependent. The energy comes from sunlight. These authors linked differences in the energy of two photons to the creation of enzymes and all biophysically constrained biodiversity. They do not seem to know what they did. Perhaps that is why they linked their findings to motion and shape processing instead of our visual perception of energy and mass in the context of the space-time continuum.
See also:  Excitatory and inhibitory subnetworks are equally selective during decision-making and emerge simultaneously during learning

Overall, higher visual areas present segregated encoding of spatiotemporal features that might underpin distinct computations, such as processing of visual motion and shape.

Unfortunately, the claim that equally selective excitatory and inhibitory subnetworks emerge simultaneously during decision-making exemplifies human idiocy.
So does this claim attributed to Kevin J. Mitchell (see the article “The ‘Innate’ beliefs of Kevin Mitchell”:

With evolution comes variation in gene expression and this forms the foundational theory for Mitchell’s research.

See also: A universal trend of amino acid gain and loss in protein evolution

Amino acid composition of proteins varies substantially between taxa and, thus, can evolve.

For comparison, all serious scientists know that natural selection for energy-dependent codon optimality links light-activated microRNA biogenesis from the physiology of reproduction to biophysical constraints on viral latency via autophagy, which help to prevent the evolution of all pathology. Constraint-breaking mutations have been linked from the virus-driven degradation of messenger RNA to all pathology in all living genera via what is known about the Virus-mediated archaeal hecatomb in the deep seafloor

What’s missing from the ridiculous misrepresentations of biologically uninformed science idiots is this fact from Riding the Evolution Paradigm Shift With Eugene Koonin

The entire evolution of the microbial world and the virus world, and the interaction between microbes and viruses and other life forms have been left out of the Modern Synthesis…

See for comparison: [Pheromonal regulation of genetic processes: research on the house mouse (Mus musculus L.)]

A study of the influence of pheromone stressor(s) on proliferating germ and somatic cells was performed on laboratory lines of house mouse in the context of the physiological hypothesis of mutation process, proposed by M.E. Lobashev in 1947. Data from experiments are presented, and results obtained during last 10-15 years are discussed. The adaptive role of cytogenetic and other observed pheromonal effects is considered. The possible existence of interorganism systems of genetic regulation is discussed, the search for and study of which may help in more complete understanding of the regularities of functioning of genetic material.

Simply put, all serious scientists know that the epigenetic effects of food odors have been linked from the physiology of pheromone-controlled reproduction in species from microbes to mice and to all human biodiversity via feedback loops.

See: Feedback loops link odor and pheromone signaling with reproduction (2005)

See for comparison: Olfaction Warps Visual Time Perception (2018)

The behavioral gain produced by a congruent relative to an incongruent odor is accompanied by elevated neural oscillatory power around the object’s flicker frequency in the right temporal region ~150-300 ms after object onset, and is not mediated by visual awareness. In parallel, odors bias the subjective duration of visual objects without affecting one’s temporal sensitivity. These findings point to a neuronal network in the right temporal cortex that executes flexible temporal filtering of upstream visual inputs based on olfactory information. Moreover, they collectively indicate that the very process of sensory integration at the stage of object processing twists time perception, hence casting new insights into the neural timing of multisensory events.

See for contrast: A single pheromone receptor gene conserved across 400 million years of vertebrate evolution

In this study, we propose that ancV1R emerged in the common ancestor of bony vertebrates during the Silurian Period >400 million years ago (Fig. 2B), thereby shedding light on the origin of the VNO during vertebrate evolution.

Receptors do not emerge and vertebrates do not evolve during millions of years. The virus-driven degradation of messenger RNA prevents the evolution of anything except pathology in the context of  the virus-mediated degradation of messenger RNA in bacteria. The bacteria become archaea and L-forms.
I provide the link, again, to Virus-mediated archaeal hecatomb in the deep seafloor in an effort to show others how to link feedback loops from food energy-dependent pheromone-controlled viral latency to all biophysically constrained biodiversity.
Intelligent scientists will continue to link the sense of smell in bacteria to our visual perception of mass and energy in the context of the space-time continuum via The Influence of MicroRNAs on Mitochondrial Calcium

While there is still much work to be done with regards to miRNA import into the mitochondria, several groups have documented that MitomiRs can regulate [Ca2+]m entry. The potential for miRNA therapeutics is limitless, and could be applied to any disease, including Alzheimers, Parkinson’s, cancer, and heart failure, which are characterized by alterations in their MitomiR profiles.

Pseudoscientists may continue to try to link abiogenesis to the creation of the innate immune system via mitochondria, which they seem to think were automagically inserted into the cell types of most eukaryotes.
Intelligent scientists are Combating Evolution to Fight Disease at the same time that biologically uninformed science idiots like Kevin J. Mitchell tout pseudoscientific nonsense such as this:

With evolution comes variation in gene expression and this forms the foundational theory for Mitchell’s research.

Mitchell’s so-called “research” could lead to the death of us all. See for comparison: Influenza 2018-2019: Are you ready?
You cannot be ready until you have learned that food energy biophysically constrains the pheromone-controlled physiology of reproduction. Despite the ridiculous claims of biologically uninformed theorists and other idiots, “Substitutions Near the Receptor Binding Site [DO NOT] Determine Major Antigenic Change During Influenza Virus Evolution” 
Viruses steal the energy that cell types must use to adapt to ecological variation. The virus-driven degradation of messenger RNA links mutations to all pathology, which is biophysically constrained in the context of epigenetic effects on cell type differentiation.
That fact has been placed into the context by using two-photon calcium imaging and a stochastic visual stimulus to catalogued the response properties of a dense sample of 40,000 neurons in V1 and six secondary visual areas of awake mice.  See:  Segregated encoding of spatiotemporal features in the mouse visual cortex
The difference in the energy of two photons links the creation of subatomic particles from what is known about Cytosis to all biophysically contrained biodiversity via what is known about the links from particle physics to the transgenerational epigenetic inheritance of healthy longevity in species from bacteria to humans.
See: Cytosis and Subatomic
See also: A human cellular noncoding RNA activates the antiviral protein 2′–5′-oligoadenylate synthetase 1
microRNAs are noncoding RNAs that do not automagically create themselves. The creation of microRNAs is light-activated and microRNA-mediated cell type differentiation has been linked from biophysically constrained viral latency to the physiology of reproduction and all biodiversity.
See for details: 2018 Meeting Online Planner and Abstract Search
(with my emphasis)
PgmNr 129: AAV gene therapy with artificial miRNA-mediated oligodendrocyte-specific gene suppression: Implication for the treatment of Pelizaeus-Merzbacher disease with PLP1 duplication.
Their virus-driven treatment is linked to virus-driven top-down causation.

PgmNr 177: Explaining gene expression: Massively parallel in-silico testing of gene expression regulators reveals large scale patterns of shared and divergent regulation across cancers and tissues.
PgmNr 216: Integration of GWAS summary statistics and miRNA-target gene network with tissue-specific miRNA expression profile identified novel pathogenesis of complex human traits implicated in tissue specificity.
PgmNr 1777/T: Combined mRNA and microRNA NGS library prep enables a more complete characterization of cell-free RNA.
PgmNr 1867/T: miRNAs may contribute to pediatric-onset multiple sclerosis by affecting immune signaling.
PgmNr 1891/T: Alcohol abuse associated allele specific expression and regulation in human brain tissue.
PgmNr 1951/T: Vegetarian diets, circulating miRNAs and healthspan in humans.
PgmNr 1975/T: Integrative genomic analysis of microRNA transcriptional responses to malaria infection.
PgmNr 2023/T: Regulation of RUNX2 gene during evolution: Functional implications in nonsyndromic craniosynostosis patients.
PgmNr 2149/T: Dysregulation of microRNAs in DR patients in Chinese Han population.
PgmNr 2275/T: Endometrial microRNA networks associated with pelvic inflammatory disease progression.
PgmNr 1642/T: SV-INFERNO: A Spark based pipeline for INFERring the molecular mechanisms of NOncoding structural variants.
PgmNr 1816/T: Demonstration of the successful extraction, library preparation, and sequencing of RNA from exosomes from plasma/serum samples frozen from the last decade.
PgmNr 3442/T: A genome wide association study on next-generation sequencing profiled plasma miRNA levels.
PgmNr 808/T: Isoform expression signatures associated with epigenetic interactions between miRNA and DNA methylation in bladder cancer.

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