Bottom-up biology
(click to enlarge)
A special issue of Nature extends examples of human idiocy touted by biologically uninformed theorists to claims about: Bottom-up biology
How is that a multitude of different molecules within a lipid envelope all come together to carry out the basic functions required to sustain organisms? Conventionally, biologists have worked from the top down to dissect how components in cells interact in their natural environment. But now technical advances are allowing researchers to take a different tack: using engineering principles to reconstruct biological processes from the bottom up. This special issue explores the potential and possible limits of bottom-up cell biology.
The special issue obfuscates the fact that the creation of energy must be linked from top-down causation to energy-dependent bottom-up cause and effect.
Focus on the benefits of building life’s systems from scratch (11/7/18)
Top down involves a decomposition process. So although a researcher can make a career out of unpicking the workings of a cellular machine such as a ribosome or mitochondrion, the starting point for such projects has always been the role of these structures in existing cells. The work is directed by the context in which it originated and into which it will fold back once complete.
No serious scientist starts with the role of these structures in existing cells. Serious scientists link energy as information from the physiology of reproduction to biophysically constrained cell type differentiation via feedback loops.
How biologists are creating life-like cells from scratch (11/7/18)
Almost anything life-like requires cellular energy, usually in the form of ATP. And although this can be added from the outside to feed a synthetic system, many biologists working on bottom-up approaches argue that a true synthetic cell should have its own power plant, something similar to an animal cell’s mitochondrion or a plant’s chloroplast, both of which make ATP.
Cytosis for ages 10+ starts with ATP and links the creation of energy to the creation of RNA and all biodiversity via claims from 1964.
Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation”
The synthesis of RNA in isolated thymus nuclei is ATP dependent.
Which biological systems should be engineered? (11/6/18)
Engineering a ‘minimal chassis’ that is capable of sustained gene expression and functional homeostasis would be an invaluable starting point for building synthetic cells that produce proteins, form tissues and remain viable for months to years. This would require detailed understanding and incorporation of metabolic pathways, trafficking systems and nuclear import and export — an admittedly tall order.
Order Subatomic and Cytosis
Learn what others ages 10+ have learned about metabolic pathways, trafficking systems and nuclear import and export.
Cell parts to complex processes, from the bottom up (11/6/18)
…changes in the size and shape of encapsulated compartments — manipulations that are easy in microfabricated systems, but not in living cells — have revealed roles for these parameters in controlling the oscillatory behaviour of proteins involved in cell division2 and the sizes of organelles3.
The oscillatory behavior of proteins is energy-dependent and it has been linked from olfaction to the physiology of reproduction and all biophysically constrained biodiversity in: Olfaction Warps Visual Time Perception
Cellular stretch reveals superelastic powers (10/31/18)
Latorre and colleagues’ work has revealed a more complex relationship between cell size and the forces that cells experience than was previously appreciated. Future studies should attempt to unravel the mechanisms that enable cells to enter a state of superelasticity and to recover from high levels of deformation. Now that we know cell shape is not an appropriate proxy for assessing cellular tension, it will be crucial to develop ways to accurately monitor tension levels in tissues, so as to better understand the factors that influence tissue shape.
Cellular stretch must be viewed in the context of energy-dependent supercoiled DNA and the virus-driven degradation of messenger RNA that links negative supercoiling to mutations and all pathology.
Active superelasticity in three-dimensional epithelia of controlled shape
Fundamental biological processes are carried out by curved epithelial sheets that enclose a pressurized lumen. How these sheets develop and withstand three-dimensional deformations has remained unclear. Here we combine measurements of epithelial tension and shape with theoretical modelling to show that epithelial sheets are active superelastic materials
See: MicroRNA-based regulation of epithelial–hybrid–mesenchymal fate determination (2013)
Reported as MicroRNA
The researchers discovered that there was an intermediate function, which is termed a “ternary,” or three-way switch. This function relates to the fact that ZEB has the ability to turn itself on due to a positive feedback system. This allows a cell to keep intermediate levels of all four proteins required for the switch. Ben-Jacob notes that the hybrid, or partially on-off state, also supports cancer metastasis by enabling collective cell migration and by imparting stem-cell properties that help migrating cancer cells evade the immune system and anticancer therapies.
Want more on the same topic?
Swipe/Drag Left and Right To Browse Related Posts:
Pea protein, p53 and cancer prevention (7)
2 MIN READ
0
The bioweapons cartel (10)
< 1 MIN READ
0
Whistleblowers found: dead or alive (8)
2 MIN READ
0
Whistleblowers found: dead or alive (1)
3 MIN READ
0
NGS vs 5th generation warfare (10)
5 MIN READ
0
miRNA-mediated preditions (7)
3 MIN READ
0
miRNA-mediated predictions (4)
2 MIN READ
0
miRNA-mediated preditions (1)
< 1 MIN READ
0
Minimal level of conflict (10)
5 MIN READ
0
Minimal level of conflict (7)
2 MIN READ
0
Minimal level of conflict (6)
2 MIN READ
0
Minimal level of conflict (4)
2 MIN READ
0
Minimal level of conflict (2)
2 MIN READ
0
Biorealism (10)
< 1 MIN READ
0
Biorealism (9)
< 1 MIN READ
0
Biorealism (7)
< 1 MIN READ
0
Biorealism (6)
2 MIN READ
0
Total recall 6000 years (6)
2 MIN READ
0
Total recall 6000 years (3)
2 MIN READ
0
Total recall 6000 years (1)
3 MIN READ
0
Censorship of perception (5)
3 MIN READ
0
Censorship of perception (4)
< 1 MIN READ
0
Censorship of perception (3)
3 MIN READ
0
Biogeochemical is geopolitical (7)
2 MIN READ
0
Biogeochemical is geopolitical (6)
2 MIN READ
0
Patenting the sun (8)
7 MIN READ
0
Patenting the sun (6)
4 MIN READ
0
Patenting the sun (5)
3 MIN READ
0
Patenting the sun (3)
2 MIN READ
0
Positive as a proton (1)
2 MIN READ
0
WHO broke the breakthrough (7)
< 1 MIN READ
0
miRNA-mediated epigenetic effects (7)
< 1 MIN READ
0
The devil is in the dirt (10)
4 MIN READ
0
The devil is in the dirt (9)
< 1 MIN READ
0
The devil is in the dirt (5)
2 MIN READ
0
The devil is in the dirt (2)
2 MIN READ
0
The devil is in the dirt (1)
2 MIN READ
0
The tipping point (revisited): 151K
2 MIN READ
0
Scientism, Atheism and Theology (7)
< 1 MIN READ
0
Scientism, Atheism & Theology (3)
< 1 MIN READ
0
Pheromone-regulated genetic processes (7)
< 1 MIN READ
0
The physics of existence (5)
2 MIN READ
0
Biophotonically charged life (4)
2 MIN READ
0
Biophotonically charged life (2)
2 MIN READ
0
Codon optimality vs systemic fraud (5)
6 MIN READ
0
Epistemic corruption (9)
2 MIN READ
0
RNA-mediated silencing (10)
4 MIN READ
0
RNA-mediated silencing (8)
2 MIN READ
0
Photonics in Forensics (4)
4 MIN READ
0
microRNA-mediated biodiversity (10)
3 MIN READ
0
microRNA-mediated biodiversity (9)
< 1 MIN READ
0
microRNA-mediated biodiversity (2)
2 MIN READ
0
Orchestrated death: Aeon
2 MIN READ
0
Orchestrated death: Francis S. Collins (2)
4 MIN READ
0
Orchestrated death: Philip C. Ball
2 MIN READ
0
microRNA-mediated election cycles (3)
3 MIN READ
0
microRNA-mediated replication timing (2)
2 MIN READ
0
Quantum biology vs atheism (2)
< 1 MIN READ
0
Defeating Disease and Communism (2)
3 MIN READ
0
Defeating Disease and Communism (1)
< 1 MIN READ
0
Pheromones protect us from viruses (2)
1 MIN READ
0
Racist fascism vs individual liberty (1)
3 MIN READ
0
From optoribogenetics to HelioRiboGenetics (5)
< 1 MIN READ
0
Coherently organized healthy longevity (1)
4 MIN READ
0
pH-dependent viral latency (6)
5 MIN READ
0
CDC’s ignorance: from roots to shoots (3)
4 MIN READ
0
The tipping point (revisited): 100K (3)
3 MIN READ
0
The tipping point (revisited): 100K (2)
5 MIN READ
0
The tipping point (revisited): 100K (1)
4 MIN READ
0
Virus-driven reduction of RNA polymerase II occupancy in hosts (1)
2 MIN READ
0
Richard Axel refutes theistic evolution
2 MIN READ
0
Viral microRNA-mediated pathology (2)
3 MIN READ
0
MicroRNA-mediated healthy longevity (3)
3 MIN READ
0
Bruce McEwen’s retrovirus legacy (2)
< 1 MIN READ
0
A microRNA-mediated healthy New Year! Thank God (2)
6 MIN READ
0
Light-activated PTEN-dependent viral latency (1)
4 MIN READ
0
microRNA-mediated prevention of diseases (1)
2 MIN READ
0
The tipping point (revisited): 95K (1)
< 1 MIN READ
0
Biological Function of Autophagy (2)
7 MIN READ
0
Biological Function of Autophagy (1)
2 MIN READ
0
MicroRNAs biophysically constrain Virus-driven pathology (5)
4 MIN READ
0
MicroRNA-mediated hypoxia vs cancer (2)
3 MIN READ
0
The tipping point (revisited): 93K (1)
4 MIN READ
0
#SFN2019 to 2012: Hiding the facts (2)
6 MIN READ
0
Multigenerational epigenetic inheritance (2)
3 MIN READ
0
Patented Creation vs Evolution of Disease (8)
3 MIN READ
0
Patented Creation vs Evolution of Disease (2)
3 MIN READ
0
MicroRNA-mediated, since 1964 (2)
3 MIN READ
0
Chemogenetic kinetics (1): Creation
3 MIN READ
0
Nutrient-dependent Pheromone-controlled cures (3)
4 MIN READ
0
Brokered regulatory leverage: Breaking Bad (1)
5 MIN READ
0
Sunlight, hydrophobicity and biodiversity (3)
5 MIN READ
0
The tipping point (revisited): 90K (1)
4 MIN READ
0
The tipping point (revisited): 89K (5)
4 MIN READ
0
The tipping point (revisited): 89K (4)
3 MIN READ
0
Relatable not debatable (1)
4 MIN READ
0
pH, amino acids, and health: Effects of sunlight and well wishes
2 MIN READ
0
Abiogenesis vs microRNA biogenesis (3)
3 MIN READ
0
The tipping point (revisited): 87K (1)
6 MIN READ
0
The tipping point (revisited): Big Data (2)
2 MIN READ
0
Ecological Adaptations: From Angstroms to Ecosystems (1)
4 MIN READ
0
Combating ignorance to fight disease (1)
4 MIN READ
0
Gamification of creationism (1)
4 MIN READ
0
Biophysical constraints on RNA synthesis (1)
9 MIN READ
0
Preprints obfuscate facts (2)
4 MIN READ
0
RNA processing and disease 2019 (1)
2 MIN READ
0
Ecological adaptation vs neo-Darwinian nonsense (2)
8 MIN READ
0
Blood music orchestrates human life (3)
3 MIN READ
0
Phytoremediation, Microbiome and CRISPR (3)
5 MIN READ
0
Phytoremediation, Microbiome and CRISPR (1)
3 MIN READ
0
Light-activated continuous environmental tracking (2)
3 MIN READ
0
The tipping point (revisited): 82,000 publications (2)
6 MIN READ
0
The tipping point (revisited): 82,000 publications (1)
3 MIN READ
0
Light and life at base pair resolution (10)
4 MIN READ
0
Dating rocks or mating for biodiversity?
6 MIN READ
0
Light and life at base pair resolution (9)
4 MIN READ
0
Light and life at base pair resolution (7)
2 MIN READ
0
Code Biology vs Predatory Publishing (2)
2 MIN READ
0
Two photon-linked biodiversity (4)
2 MIN READ
0
Two photon-linked biodiversity (3)
2 MIN READ
0
From microRNA.pro to quantumsouls.pro (1)
4 MIN READ
0
Hide and seek with science facts (8)
2 MIN READ
0
Hide and seek with science facts (1)
4 MIN READ
0
I can’t fix stupid (3)
3 MIN READ
0
10,000 reasons to believe in biophysical constraints (3)
3 MIN READ
0
10,000 reasons to believe in biophysical constraints (2)
6 MIN READ
0
War Games: False Flag Terrorism (4)
3 MIN READ
0
Creating an enzyme that kills theories (1)
< 1 MIN READ
0
Michael Bloomberg for President (NOT) in 2020
2 MIN READ
0
Quantized energy-dependent microRNA-mediated autophagy (2)
< 1 MIN READ
0
The concept of a species (3)
4 MIN READ
0
Laws of Biology vs no Laws of Physics (2)
3 MIN READ
0
Laws of biology vs no laws of physics
3 MIN READ
0
MicroRNA-mediated alternative splicing (revisited)
4 MIN READ
0
Corporate owned microRNA-mediated biodiversity
< 1 MIN READ
0
Animal welfare vs human ethology
4 MIN READ
0
Biologically uninformed science idiot: Self-defense (2)
3 MIN READ
0
The origin of information (5,4,3,2,1)
3 MIN READ
0
ATP and RNA-mediated chromosomal stability
3 MIN READ
0
Ecological adaptations vs the randomness of evolution (3)
4 MIN READ
0
Abiogenesis vs microRNA biogenesis (2)
7 MIN READ
0
The eternal significance of microRNAs (1)
< 1 MIN READ
0
Sympatric Speciation vs pseudosceintific nonsense (4)
2 MIN READ
0
NSF’s parrot and other parrots
2 MIN READ
0
Nick Lane refutes theistic evolution (1)
5 MIN READ
0
Conceptual critique: Innateness vs the death gene (2)
5 MIN READ
0
A reversible TCA cycle in a thermophile (3)
4 MIN READ
0
A reversible TCA cycle in a thermophile (2)
3 MIN READ
0
A mental health problem at the highest level (3)
7 MIN READ
0
Diet-driven RNA interference and mental health (3)
4 MIN READ
0
Anti-entropic sunlight: Schrödinger’s Creationist Secret? (3)
6 MIN READ
1
The MicroRNAome Strikes Back: A Sokalian hoax (9)
4 MIN READ
0
The MicroRNAome Strikes Back: A Sokalian hoax (4)
5 MIN READ
0
The MicroRNAome Strikes Back: A Sokalian hoax (3)
4 MIN READ
0
The tipping point (revisted): 69,000 publications
4 MIN READ
0
Diet-driven RNA interference and cancer prevention (3)
6 MIN READ
0
Enzyme-constrained interethnic diversity (8)
< 1 MIN READ
0
Enzyme-constrained interethnic diversity (7)
6 MIN READ
0
Interethnic genetic similarities and differences (2)
4 MIN READ
0
Quantized energy-dependent viral trophism
4 MIN READ
0
The “walking fish” walks straight from quantum physics to quantum souls
6 MIN READ
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (7)
4 MIN READ
0
Darwinian adaptation: a clear evolutionary trail?
4 MIN READ
0
The overwhelming ignorance of sex researchers (2)
4 MIN READ
0
Energy-dependent base editing and correction of mutations (2)
9 MIN READ
0
Exposing the 2nd Law to more ridicule (1)
6 MIN READ
0
Reporting new scientific truths is not allowed in the USA (2)
6 MIN READ
0
Denying Creation via RNA-directed DNA methylation
4 MIN READ
0
Light-activated error-free DNA repair (4)
3 MIN READ
0
A null mutation and healthy longevity?
4 MIN READ
0
Light-activated error free DNA repair
5 MIN READ
0
Eutrophication and phosphorylated biodiversity
6 MIN READ
0
A mental health problem at the highest level
2 MIN READ
0
Natural selection for racism and all pathology
6 MIN READ
0
Pheromones biophysically constrain RNA-mediated biodiversity (1)
5 MIN READ
0
From base editing to RNA editing (5)
< 1 MIN READ
0
The next reformation: 500 years too late? (1)
< 1 MIN READ
0
The next reformation: 500 years too late? (2)
2 MIN READ
0
The next reformation: 500 years too late? (3)
5 MIN READ
0
From base editing to RNA editing (2)
7 MIN READ
0
Cryo-EM: More than a suggestion
< 1 MIN READ
0
Long-term adaptation replaces evolution (2)
2 MIN READ
0
Exome Sequencing Impact in Routine Care
4 MIN READ
0
Losers: rediscovering an epigenetic key
2 MIN READ
0
Virulence: Out of stock
2 MIN READ
0
Until death: Virus-driven failure of multisensory integration (3)
4 MIN READ
0
Energy-dependent structure and function: Until death (5)
4 MIN READ
0
Energy-dependent structure and function: Until death (3)
3 MIN READ
0
Energy-dependent structure and function: Until death (2)
5 MIN READ
0
Energy-dependent structure and function: Until death (1)
4 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (7)
4 MIN READ
0
Until death: Virus-driven failure of multisensory integration (1)
4 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (6)
5 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (4)
4 MIN READ
0
Predicting who wins the 2017 Nobel Prizes
4 MIN READ
0
Life and death via chemical effects on photosynthesis
8 MIN READ
0
Dispelling the ignorance of theorists
4 MIN READ
0
Sci-Hub vs limits on the dissemination of information
6 MIN READ
0
Science vs Secularism: Molecular Mechanisms or Math?
6 MIN READ
0
Pseudoscientists hate what science explains!
3 MIN READ
0
Robert Sapolsky’s legacy of atheistic pseudoscientific nonsense
4 MIN READ
0
Automagical protein creation sans energy
9 MIN READ
0
Solar analemma with a total solar eclipse
2 MIN READ
0
The Origin of Information (4)
4 MIN READ
0
Can protein folding chemistry be understood by theorists?
5 MIN READ
0
Energy-dependent physical and biophysical constraints (10)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (8)
5 MIN READ
0
Energy-dependent physical and biophysical constraints (3)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (1)
5 MIN READ
0
Epigenetic effects of stress by Bruce McEwen (2)
3 MIN READ
0
The emergence of light as energy from a life-giving star (2)
2 MIN READ
0
The emergence of light as energy from a life-giving star
11 MIN READ
2
God’s shrinking role in salvation (3)
9 MIN READ
0
God's shrinking role in salvation (3)
9 MIN READ
0
MicroRNAs GnRH and the failure of sex research
7 MIN READ
0
Food energy-dependent cell type differentiation (2)
10 MIN READ
0
Hard Science vs the neo-Darwinian “magic box”
9 MIN READ
0
Infections and age change the odor of wine and people
4 MIN READ
0
Food energy-dependent epigenetic adaptation (3)
3 MIN READ
0
Food energy-dependent epigenetic adaptation (2)
< 1 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (5)
4 MIN READ
0
Energy-dependent microRNA biogenesis
4 MIN READ
0
Draining the academic swamp of parasites
3 MIN READ
0
Dispensing with all pseudoscientific nonsense about evolution (1)
5 MIN READ
0
Virus-driven downsizing of the human brain (4)
2 MIN READ
0
Epigenetically-effected nucleosome repositioning sheds Dobzhansky’s light on evolution
3 MIN READ
0
Synthetic RNA-based switches
2 MIN READ
0
Cytosis: Biology Content
7 MIN READ
0
Cytosis: A Cell Biology Board Game
< 1 MIN READ
0
Life in your UV light-constrained galaxy
5 MIN READ
0
Energy-dependent pheromone-controlled entropy (3)
2 MIN READ
0
Energy-dependent pheromone-controlled entropy (4)
3 MIN READ
0
Proof: Sunlight is energy as information
< 1 MIN READ
0
RNA-mediated adult learning, memory, and neurogenesis
3 MIN READ
0
Ab initio cell wall invention, emergence, and evolution (1)
2 MIN READ
0
Theistic evolutionists fight back and lose (2)
4 MIN READ
0
Theistic evolutionists fight back and lose
4 MIN READ
0
Emily Witkin refutes theistic evolution
2 MIN READ
0
Francis S. Collins refutes theistic evolution
6 MIN READ
0
Energy is information. Objections over ruled. You’re fired!
7 MIN READ
0
George Church refutes theistic evolution (3)
5 MIN READ
0
George Church refutes theistic evolution (2)
2 MIN READ
0
George Church refutes theistic evolution
5 MIN READ
0
Natural selection for codon optimality and quantum viruses
5 MIN READ
0
Mitochondria do not adapt
2 MIN READ
0
Physicists: Desperate Acts (revisited)
6 MIN READ
0
Energy as information and constrained endogenous RNA interference (3)
4 MIN READ
0
Dobzhansky 1973 and precision medicine (5)
3 MIN READ
0
Dobzhansky 1973 and precision medicine
6 MIN READ
0
Twisted theories and weaponized facts
3 MIN READ
0
Autophagy: from pre-mRNAs to microRNAs, enhancers, QTLs et al.
6 MIN READ
0
Mutations: the “driving force” behind human brain complexity?
6 MIN READ
0
Mutations: the "driving force" behind human brain complexity?
6 MIN READ
0
Science journalists or paid propagandists? (2)
3 MIN READ
0
Science journalists or paid propagandists?
5 MIN READ
0
Critical values expose virus-driven energy theft (2)
4 MIN READ
0
Critical values expose virus-driven energy theft
6 MIN READ
0
Anti-entropic energy and the “Music of Life”
3 MIN READ
0
Anti-entropic energy and the "Music of Life"
3 MIN READ
0
Chirality is reality
6 MIN READ
0
Energy-dependent hydrogen bonds in supercoiled DNA
7 MIN READ
0
Energy-dependent chirality
6 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016
12 MIN READ
0
Energy-dependent oscillating gene networks organize life
4 MIN READ
0
Anti-entropic virucidal energy as information
10 MIN READ
0
Bio-functional information
3 MIN READ
0
Bird-brained theorists
< 1 MIN READ
0
Energy-dependent self-organization and self repair
8 MIN READ
0
Autophagy is the antiphage defense strategy
3 MIN READ
0
Energy-dependent de novo creation and neurogenesis
7 MIN READ
0
Theories vs facts about polycombic adaptation
3 MIN READ
0
Tasting light links energy from creation to adaptation
9 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Metabolic Phenotyping Research
2 MIN READ
0
De novo gene creation: Ignoring the experimental evidence
7 MIN READ
0
Energy-dependent purifying selection / autophagy (6)
3 MIN READ
0
Building delicious base pairs in class. It’s elementary Watson and Crick
3 MIN READ
0
Building delicious base pairs in class. It's elementary Watson and Crick
3 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (8)
4 MIN READ
0
Energy-dependent maternal-to-zygotic transition
6 MIN READ
1
Epigenetically effected energy-dependent fluorescence (2)
6 MIN READ
0
Epigenetically effected energy-dependent fluorescence
5 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (7)
3 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (5)
2 MIN READ
0
From precis to pre-mRNA and proof of concept in F1, F2, F3
6 MIN READ
0
From Precis to Proof in 6000 years
9 MIN READ
0
Coulombic interactions facilitate polycombic adaptation
5 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (3)
< 1 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
Polycombic ecological adaptation as a science, not a theory
3 MIN READ
0
Biological evolution as a philosophy, not a science
6 MIN READ
0
Attacking Young Earth Creationists
5 MIN READ
0
Did evolution autophosphorylate your kinases? (3)
2 MIN READ
1
Predictable idiosyncratic evolved convergence
3 MIN READ
0
The natural success of RNAi and failed treatment
7 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy (2)
6 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy
3 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
Hypothesis free pseudoscience vs facts (5)
6 MIN READ
0
Hypothesis free pseudoscience vs facts (4)
5 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
The Aquatic Ape / Waterside Ape divergence
6 MIN READ
0
Linking RNA structure to function
3 MIN READ
0
Plant microRNAs slow virus-driven aging
3 MIN READ
0
Protecting 4 billion people from virus-driven entropy
< 1 MIN READ
0
Energy-dependent cellular communication
3 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Antithetical conclusions (7)
3 MIN READ
0
Antithetical conclusions (5)
4 MIN READ
0
Antithetical conclusions (4)
3 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
GC-rich neo-Darwinian train wreck
5 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (3)
< 1 MIN READ
0
Biophysically constrained cell type differentiation
3 MIN READ
0
From angstroms to ecosystems
7 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
Q and A: Energy-dependent cell type differentiation
10 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity
4 MIN READ
0
RNA-mediated programming of E.coli
< 1 MIN READ
0
Did “Nature” kill Steve Jobs? (2)
6 MIN READ
0
Virus-driven downsizing of the human brain (2)
< 1 MIN READ
0
Innate immunity and multiplexing
7 MIN READ
0
Model vs theory: Progress report!
8 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
RNA methylation, behavior, and disease
6 MIN READ
0
Modelling life scientifically: RNA-mediated events
12 MIN READ
0
Energy-dependent RNA methylation (8)
4 MIN READ
0
Energy-dependent RNA methylation (6)
9 MIN READ
0
Energy-dependent RNA methylation (2)
5 MIN READ
0
Thermotolerance and longevity (2)
3 MIN READ
0
Virus-driven energy theft: definition?
5 MIN READ
0
Energy-dependent biodiversity (4)
4 MIN READ
0
Energy-dependent biodiversity
5 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
Half truths support theories without facts
4 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Jay R. Feierman: twenty years of antagonism
5 MIN READ
0
Energy dependent RNA-mediated immunity (5)
4 MIN READ
0
Energy dependent RNA-mediated immunity (3)
8 MIN READ
0
Energy dependent RNA-mediated immunity (2)
10 MIN READ
0
Energy-dependent RNA-mediated immunity (1)
10 MIN READ
0
RNA-mediated DNA modifications
5 MIN READ
0
Science vs semantics
4 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11 MIN READ
0
Bacteria see the light and they adapt
7 MIN READ
0
The Light and Darkness of “Evolution 2.0”
11 MIN READ
0
Will modern human populations adapt to the Zika virus?
5 MIN READ
0
Models of scientific literacy
3 MIN READ
0
The radical pair mechanism of ecological speciation
3 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs (4)
4 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
Another failed rescue attempt
5 MIN READ
0
Juvenile hormone links atoms to ecosystems
3 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Ecological genomics: teleophobes respond (too late)
10 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Perry Marshall: too much information for atheist PZ Myers
3 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
Assumptions prove ignorance
5 MIN READ
0
NORAD: air defense and defense against genomic entropy
7 MIN READ
0
Did Dobzhansky see the UV light of creation?
10 MIN READ
0
Manufacturing fossil “evidence”
4 MIN READ
0
RNA-mediated theory killers (3)
7 MIN READ
0
RNA-mediated regulatory mechanisms link microbes to humans (3)
5 MIN READ
0
Essential pseudoscientific concepts of atheism
3 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (4)
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair
2 MIN READ
0
Plasma created by sunlight and RNA–mediated epigenetic heredity
2 MIN READ
0
Stress-perturbed mitochondrial dysfunction
4 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Sensationalizing no new mechanism
2 MIN READ
0
Fossils vs cell types and the brain
3 MIN READ
0
Designing, engineering, and protecting biodiversity
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Controled Stem Cell Expansion
3 MIN READ
0
Human pheromone deniers: What’s next?
5 MIN READ
0
700 million years of evolution?
5 MIN READ
0
RNA-mediated retrotransposon-mediated biodiversity
3 MIN READ
0
Mystery machine vs model (2)
2 MIN READ
0
Energy and evolution: another opinion?
2 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Microbes to humans 2015 Nobel Prize
2 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Viruses come alive: Tree of life pseudoscience
6 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
A Darwinian pediatrician and expected life span
2 MIN READ
0
A 5-10K comparison of design principles to evolution
3 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Exosomes and the RNA-mediated future of medicine
5 MIN READ
0
From fertilization to RNA-mediated events and back
2 MIN READ
0
Phytochemical link from the sun to cell types
2 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
A “new” code enables ecological adaptation
4 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
The “great filter” is an epigenetic trap
4 MIN READ
0
Information and communication (2)
6 MIN READ
0
Unraveling evolutionary pseudoscience
2 MIN READ
0
From “Blood Music” to Evolution 2.0
5 MIN READ
0
Ecology replaces the extended evolutionary synthesis
4 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
Viruses, amino acids, and somatic cell types
4 MIN READ
0
Big Bang Cosmology vs Reality
< 1 MIN READ
0
Hematopoiesis and practopoiesis
4 MIN READ
0
Koonin: viruses killed neo-Darwinism
3 MIN READ
0
RNA-mediated morphological AND behavioral phenotypes
2 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Riding the wrong direction
3 MIN READ
0
Decreased phenotypic variation: Faith in Facts
7 MIN READ
1
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
Olfactory perception of genetic information
2 MIN READ
2
Nutrient stress-induced RNA-mediated pathology
< 1 MIN READ
0
RNA-mediated development (2)
< 1 MIN READ
0
Creating and maintaining the human virome
2 MIN READ
0
Ignoring top-down causation
2 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Viruses and the human-like microbiome
3 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
One amino acid substitution, genes, and brain activity
3 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
A lighting requirement for life
11 MIN READ
3
Scientists lose. A sci-fi author gains credibility
2 MIN READ
0
Computing via phosphorylation and fixation
3 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Tissue type variation and expression of genes
< 1 MIN READ
0
Chance mutations — not natural selection
5 MIN READ
0
How to find a “holy grail” under your nose
3 MIN READ
0
Physics, chemistry, light, and life
2 MIN READ
0
An epigenetic mark links algae, worms, and flies
2 MIN READ
0
Thermodynamics and protein folding landscapes
2 MIN READ
0
RNA-mediated silencing of a chromosome
3 MIN READ
0
Pathology constrains X-linked evolution
2 MIN READ
0
Feedback loops link insects to human brains
2 MIN READ
0
DNA Methylation and organized genomes (2)
10 MIN READ
0
DNA Methylation and organized genomes
7 MIN READ
0
Amino acid-dependent cell type differentiation
8 MIN READ
0
Origin of life and cancer (1,2,3)
2 MIN READ
0
MicroRNAs and invasive phenotypes
< 1 MIN READ
0
Silencing genes and serious scientists
3 MIN READ
0
The miRNA/mRNA balance: a suboptimal strategy?
2 MIN READ
0
Deeply ingrained thoughts
< 1 MIN READ
0
Too many targets for theories
3 MIN READ
0
Methylation maintains cell type differences
3 MIN READ
0
Creating nothing but a theory
4 MIN READ
0
Viruses and ecologically adapted animals
2 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Anti-entropic solar energy
5 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
Two types of microRNA are not double agents
2 MIN READ
0
Epigenetics Skeptism
5 MIN READ
0
Is DNA-directed transcription RNA-mediated?
2 MIN READ
0
RNA directed DNA methylation and cell types
4 MIN READ
0
Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs
2 MIN READ
0
Reverse phosphorylation
7 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
From 3-D to epigenetically-effected 4-D genome make-up
5 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
Nutritional epigenetics, exercise, and immune system integrity
4 MIN READ
0
What if Darwin was not still dead?
2 MIN READ
0
How fast can evolutionary theory be changed?
5 MIN READ
0
Biological energy and a microbiome model of a light-driven time machine
3 MIN READ
0
Sneaking up from behind (2)
3 MIN READ
0
An epigenetic trap (the sequel)
10 MIN READ
0
All of "like kind" in the (bigger) family
6 MIN READ
1
Environment epigenetically shapes the immune system
3 MIN READ
0
Beneficial microbes kill beneficial mutations
4 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
Unconstrained evolutionary innovability
4 MIN READ
0
Mutagenesis: Replacing facts with theories
5 MIN READ
0
Amino acid homeostasis for a Happy New Year!
6 MIN READ
0
From Hydra to humans vs a Lakatosian research program
4 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
Chemical ecology and RNA-mediated control of DNA loops
< 1 MIN READ
0
Jumping back: Science or Pseudoscience? (2)
2 MIN READ
0
Jumping back: Science or Pseudoscience?
6 MIN READ
0
Glycine and GnRH: Am I being pedantic?
4 MIN READ
0
Extensive molecular evidence vs ridiculous theories
2 MIN READ
0
Dual genomes: exposing the evolution industry
5 MIN READ
0
Sackler Colloquium: Effects or AFFECTS on Behavior
2 MIN READ
0
Thermodynamic constraints and ecological adaptations sans evolution
6 MIN READ
0
Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
0
Biologists puzzled by evolved RNAs and decaying DNA
6 MIN READ
0
SNPs and millions of small variations in the human genome
3 MIN READ
0
Making sense of quotes scattered across disciplines
2 MIN READ
0
Complex behaviors of cell types in cancer
6 MIN READ
0
We need pattern recognition, not a prologue
6 MIN READ
0
Sexual differentiation of cell types in plants
2 MIN READ
0
In theory, or supported by experimental evidence?
5 MIN READ
0
It’s cell type differention, not cell fate determination (2)
3 MIN READ
0
No excuses: Creation and the meaning of organismal complexity
7 MIN READ
0
No understanding of biodiversity
2 MIN READ
0
Behavioral ecology: please continue to believe in our fantasies
3 MIN READ
0
2014 and 2004 Nobel Prize in Medicine
3 MIN READ
0
RNA-mediated genetic engineering (Part 2)
3 MIN READ
0
RNA-mediated events are not a matter of faith
2 MIN READ
0
Color vision refutes the evolutionary dogma of gene duplication
4 MIN READ
0
Unassailable evidence vs assumptions
4 MIN READ
0
Forces of "Nature" limit dissemination of information
4 MIN READ
0
Metabolism, fixation, health or neurodegerative disorder
2 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Physics denied; pseudoscientific nonsense accepted
2 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Mathematical model: microRNA and epigenetic regulation
2 MIN READ
0
Quantum physics meets Evolutionary Psychology News
2 MIN READ
0
A molecular visualizer of worthwhile molecular biology
2 MIN READ
0
RNA-mediated species diversification from microbes to primates
3 MIN READ
0
Insect homology and diversity attributed to mutations
2 MIN READ
0
The quantum biology of consciousness
3 MIN READ
0
Genes and Race: Human History?
2 MIN READ
0
Don't tell the Creationists
2 MIN READ
0
Social experiences epigenetically effect gene networks
2 MIN READ
0
Functional coding variants are not mutations
2 MIN READ
0
Understanding the role of mutations and evolution
4 MIN READ
0
Hormones effect sensitivity to androsterone
2 MIN READ
0
Music to our ears and song in birds: a common sense approach
2 MIN READ
0
The challenges of a Darwinian approach to anything
3 MIN READ
0
How Species Diversify
2 MIN READ
0
The same neural mechanisms are at work in worms and humans
2 MIN READ
0
Evolutionarily innovative DNA mistakes?
< 1 MIN READ
0
Epigenetic effects on the evolution of behavior
2 MIN READ
0
Human pheromones and the definition of life
2 MIN READ
0
Human pheromones and inner conflict about evolution (1102 words)
4 MIN READ
0
Human pheromones and the visual appeal of other people (Part Three)
2 MIN READ
0
Human pheromones and the visual appeal of other people (Part Two)
2 MIN READ
0
Adam’s rib: Pheromones and the adaptive evolution of human sexuality
2 MIN READ
0
A fallacious leap? Ancestral and derived traits
3 MIN READ
0
Modeling odor processing in microbes, mice, and mankind
2 MIN READ
0
Human Pheromones in Socioaffective Neuroscience & Psychology
2 MIN READ
0
The biology of behavior: Seeing more clearly
< 1 MIN READ
0
Do Pheromones Play a Role in Our Sex Lives: Scientific American
< 1 MIN READ
0
Docosahexaenoic acid and autism: praying for hope, or preying on hope
< 1 MIN READ
0
Timing is key in the proper wiring of the brain: study
2 MIN READ
0
Progress in brain research (e.g., starting over)
< 1 MIN READ
0
Avian recognition of human faces
< 1 MIN READ
0
A lesser role for olfaction and pheromones in humans?
1 MIN READ
0
Pheromones and sexual behavior in birds
< 1 MIN READ
0
