I can’t fix stupid (3)

By: James V. Kohl | Published on: November 26, 2018

Summary: Energy-dependent amino acid substitutions prevent the evolution of virus-driven pathology.
See also my responses to Theorists Debate How ‘Neutral’ Evolution Really Is
Correction added on Nov. 9: The original version of this article misstated the key input required by the neutral model.

…figuring out exactly how — and how much — selection is inexorably shaping our genomes after all.

It’s 90% selection for energy-dependent biophysically constrained viral latency. See: Virus-mediated archaeal hecatomb in the deep seafloor
See also: Alzheimer’s disease: mounting evidence that herpes virus is a cause (2018)
Alzheimer’s disease could be caused by herpes virus, warn experts (2016)

We are saying there is incontrovertible evidence that Alzheimer’s Disease has a dormant microbial component. We can’t keep ignoring all of the evidence.

I am saying that most people continue to ignore all the evidence.
For a recent summary of all the evidence, see Olfaction Warps Visual Time Perception
The pheromones of species from microbes to humans biophysically constrain viral latency.
This was the next thing I read morning: Could consciousness all come down to the way things vibrate? (November 9, 2018)

Our resonance theory of consciousness attempts to provide a unified framework that includes neuroscience, as well as more fundamental questions of neurobiology and biophysics, and also the philosophy of mind. It gets to the heart of the differences that matter when it comes to consciousness and the evolution of physical systems.

It is all about vibrations, but it’s also about the type of vibrations and, most importantly, about shared vibrations.

See for comparison: The vibrational theory of olfaction for the win (October 31, 2017)

…he and his co-authors delve into more of the specifics of olfactory receptors, including particular amino acid motifs, metal binding capacities, and disulphide bridge redox status. It turns out that amino acid side chains alone frequently pull off some rather interesting electron transfer effects without the need for fancy co-enzymes or prosthetic groups. Although there are only a few cases in which this has been proposed, we can take a brief anecdotal look at how this mechanism operates in other proteins.

For instance:

…an intrinsic covalently-bonded chromophore is spontaneously constructed from the side chains of the tripeptide Ser65-Tyr66-Gly67.

If you have been taught to believe in the spontaneous construction of any functional structure, you may be even less intelligent than Jay R. Feierman, Tam Hunt, Jonathan Schooler, and  John Hewitt.
They are the losers who will continue to contribute to more unnecessary suffering and premature deaths. They regurgitate pseudoscientific nonsense (Jay R. Feierman) and the losers (Tam Hunt, Jonathan Schooler) try to pretend they have not always been losers.
See: Kalevi Kull: Censorship & Royal Society Evo Event

Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge. — Kalevi Kull

John Hewitt simply blocks the dissemination of information that conflicts with his ridiculous theories. Clearly it takes a team of ignorant theorists to prevent others from linking feedback loops from odors and pheromones to biophysically constrained viral latency until others have been convinced that naturally occurring RNA interference is worth the cost they will be forced to pay for it. .
See: Landmark RNAi drug gets off to a slow start in sales, but Alnylam calls for patience
This exemplifies the cost of electing Democrats.
Onpattro will have an list price of $450,000 per patient per year for the average patient.
See: Alnylam Prices First Gene Silencing Drug At $450,000 Per Patient, But Offers Money-Back Guarantee
See for comparison: Get Well in the RNAi Way-RNAi, A Billion Dollar Baby in Therapy
Naturally occurring RNAi protects all organized genomes from the virus-driven degradation of messenger RNA that links mutations to all pathology at every level of biological organization.
It was  Patented by Church et al: as RNA-Guided Human Genome Engineering

Be a patient patient and try to pay for what most people will find is unaffordable treatment. You will probably become bankrupt before most people learn that naturally occurring RNA interference protects all organized genomes from the virus-driven degradation of messenger RNA, which links mutations to all pathology at every level of biological organization (from angstroms to ecosystems).

Watch for the next attempt to daze and confuse you after reading Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems
See also the obfuscation at the: Twitterbot for microRNA papers and TwitterBot for eQTL papers
Remember Russian bots were used to sow divisions on vaccines, researchers say
and see: Donald Trump Declares Flu Shots Are “Virtually Totally Ineffective”

I’ve seen a lot of reports that the last flu shot is virtually totally ineffective.

Do you want to know why flu shots are virtually totally ineffective?

Viruses do not evolve.

See: Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution

Koel et al. (p. 976) show that major antigenic change can be caused by single amino acid substitutions.

Energy-dependent amino acid substitutions prevent the evolution of virus-driven pathology.

See also: Virus-breaking in Tulips and works on the tobacco mosaic virus.

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