Light and life at base pair resolution (6)
(click to enlarge)Conclusion: If Nick MacKnight fails to link thermodynamic cycles of protein biosynthesis and degradation to heat-stress linked viral replication in corals via what is known about the virus-driven degradation of messenger RNA, the Society for Integrative and Comparative Biology may never recover from the pseudoscientific nonsense touted by Billie J. Swalla and others such as LL Moroz who believe in neo-Darwinian theories.
For contrast viral replication and the degradation of messenger RNA have linked mutations to all pathology.
See: miR-18a reactivates the Epstein-Barr virus through defective DNA damage response and promotes genomic instability in EBV-associated lymphomas
Taken together, these results indicate that DNA-damaging agents and host microRNAs play roles in EBV reactivation. Our study supported the interplay between host cell DDR, environmental genotoxic stress and EBV.
Although ultraviolet light has been linked from genotoxic stress (aka DNA damage) to mutations and pathology, only recently has the anti-entropic virucidal energy of sunlight been linked from microRNA biogenesis in plants to DNA repair and biophysically constrained viral latency in all living genera via the physiology of pheromone-controlled reproduction in insects.
Now, mounting evidence attests to the fact that all pathology can be prevented via diet-driven changes in microRNA biogenesis.
For example, Newly knighted cancer scientist Mel Greaves explains why a cocktail of microbes could give protection against disease
…the disease has nothing to with power lines or nuclear fuel reprocessing stations, as has been suggested in the past [along with other ridiculous suggestions made by conspiracy theorists], but is caused by a double whammy of interacting prenatal and environmental events…
The interacting events are food energy-dependent and microRNA-mediated in the context of the transgenerational epigenetic inheritance of healthy longevity or pathology. The virus-driven degradation of messenger RNA causes the mutations that have been linked to all diseases at all ages.
Once again, we see that people will listen to an expert who touts a ridiculous theory of mutation-driven cause, and fail to ask “What causes the mutation?”
See also: Evidence of Plant-encoded miRNAs in Green Peach Aphid (Myzus persicae) Gut (2019 meeting presentation abstract)
Our results provide foundational evidence for the regulation of aphid gene expression by plant-encoded miRNAs. This knowledge both advances understanding of cross-kingdom gene regulation in plants and insects, and expands understanding of the regulatory interactions surrounding aphid feeding.
For a historical perspective, see: Aphid amino acid transporter regulates glutamine supply to intracellular bacterial symbionts (2014)
The amino acid transporters that regulate the supply of energy in bacterial symbionts are biophysically constrained by food energy and pheromones that regulate the physiology of reproduction in species from microbes to humans.
The energy-dependent creation of ATP, microRNAs, enzymes and the sense of smell in bacteria is required to link changes in angstroms to ecosystems. Without the creation of the sun’s anti-entropic virucidal energy, pseudoscientists and so-called science journalists cannot get from the Virus-mediated archaeal hecatomb in the deep seafloor to Eukaryotic plankton diversity in the sunlit ocean
But see: Caribbean Coral Species Differ in Susceptibility and Immune Response to White Plague Disease (Meeting abstract)
Weighted Gene Correlation Network Analysis was applied to infer the relationship between gene expression profiles and white plague exposure, infection, and tissue loss and relevant modules of gene networks were identified as significantly correlated.
Nick MacKnight et al., appear to be ready to present more than inferences and correlations.
He wrote: https://twitter.com/NickMacKnight/status/1080538664042680320
Teaching the pups and my lady about the phenotypic, gene regulation, and microbial variance across 7 Caribbean #coral species when exposed to White Plague Disease in preparation for my SICB talk on Jan 4th at 9:30 am, Room 13! @SICBtweets
I asked: https://twitter.com/microRNApro/status/1080542694840127488
Do you think the bacterial disease is caused by bacteriophages? If so, have you linked the virus-driven degradation of messenger RNA to all pathology in all living genera, yet? If not, see: Virus-mediated archaeal hecatomb in the deep seafloor
I'm well-educated in that context with 40 yrs experience in the medical laboratory. I co-authored this 1996 review. https://t.co/6dCuuvOP1y From Fertilization to Adult Sexual Behavior
Have you seen: Eukaryotic plankton diversity in the sunlit ocean https://t.co/AOzSunvy1L— James V. Kohl (@microRNApro) January 3, 2019
Be careful to not surprise anyone too much. They may become enemies. For example, Billie J. Swalla banned me from participation on FB SICB after my comments on the claim that "…we were unable to experimentally detect microRNAs…" https://t.co/sSR8v7pOYa. https://t.co/0vkO003V8u
— James V. Kohl (@microRNApro) January 2, 2019
With others she wrote: "… data are consistent with the hypothesis that ctenophore neural systems… evolved independently from those in other animals." Food energy-dependent biophysically constrained viral latency prevents hecatombic evolution via polycombic adaptations.
— James V. Kohl (@microRNApro) January 2, 2019
The problem arose in claims from LL Moroz and others because the claims were inconsistent with my model. Polese et al., 2015 had already cited Kohl (2013), which was a refutation of neo-Darwinism. See "Role of olfaction in Octopus vulgaris reproduction" https://t.co/WrWtXfXcNF
— James V. Kohl (@microRNApro) January 2, 2019
Since then, publication of Olfaction Warps Visual Time Perception and Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems have made Swalla and others look even more foolish.
If Nick MacKnight fails to link thermodynamic cycles of protein biosynthesis and degradation to heat-stress linked viral replication in corals via what is known about the virus-driven degradation of messenger RNA, the Society for Integrative and Comparative Biology may never recover from the pseudoscientific nonsense touted by Billie J. Swalla and others such as LL Moroz, who will almost undoubtedly continue to tout neo-Darwinian theories.
