Ecological adaptation vs neo-Darwinian nonsense (5)

By: James V. Kohl | Published on: February 20, 2019

From two years ago: February 20, 2017 at 11:57 AM

The dramatic decline in page views from a peak of 2304 in October 2016 with an increase in the bounce rate has begun to run in reverse at RNA-mediated.com

I think that more people have begun to realize that every aspect of neo-Darwinian nonsense has never been supported by experimental evidence of biologically-based cause and effect. If not, the pseudoscientific nonsense may prevail, but I doubt that. I’ve posted nearly 1000 blog posts that refute theistic evolution in every way possible, but mostly by linking the sun’s anti-entropic energy to healthy longevity and by linking virus-driven energy theft from mutations to all pathology.

I founded this domain, microRNA.pro on 6/6/18,  because it became clear that every aspect of RNA-mediated cell type differentiation started with the creation of sunlight and the creation of microRNAs in plants.
See: A Quick HYL1-Dependent Reactivation of MicroRNA Production Is Required for a Proper Developmental Response after Extended Periods of Light Deprivation 7/18/18

…plants alter microRNA (miRNA) biogenesis in response to light transition.

See for review: Finding quinoa’s sweet spot to feed the world 2/19/17

Quinoa exemplifies the established links from the light-activated creation of the innate immune system to endogenous RNA interference and healthy longevity in all living genera. Healthy longevity links the nutrient energy-dependent pheromone-controlled physiology of reproduction in soil bacteria and in marine microbial life to the fertilization and adult sexual behavior of mammals via amino acid substitutions in supercoiled DNA via quorum sensing in bacteria.

See: From Fertilization to Adult Sexual Behavior (1996)

We included a section on molecular epigenetics and linked what organisms eat to the pheromone-controlled physiology of reproduction in yeasts to humans.

Update February 20, 2019

The food energy-dependent fixation of RNA-mediated amino acid substitutions has been linked from the creation of the sun’s anti-entropic virucidal energy to the nucleic acid-microRNA-peptide nanocomplex, which protects all organized genomes in all living genera from all pathology. The light-activated assembly of the nanocomplex was also linked to the cure for all cancers. That fact was reported by researchers from Israel who were attacked for making what some experts somehow determined was a false claim.

See: Experts Decry Israeli Team’s Claims That They Have Found The Cure For Cancer (1/30/19)

The cure for cancer predictably links everything under the sun to biophysically constrained viral latency in the context of the pheromone-controlled physiology of reproduction in species from marine microbes and terrestrial microbes to humans.

See: Virus-mediated archaeal hecatomb in the deep seafloor (2016) and Eukaryotic plankton diversity in the sunlit ocean (2015)

Serious scientists have always been skeptical about the claims made by neo-Darwinian theorists. They have forced theorists to evolve their neo-Darwinian pseudoscientific nonsense to include what is known about ecologically adapted Squid genomes in a bacterial world (2/19/19 – subscription required)

Animals are living in a microbial world. Bacteria, Archaea, and often eukaryotic microorganisms are ubiquitous and intimate associates of all multicellular organisms (1). Many of these microbes improve the fitness of their hosts by affecting multiple traits, including growth rates, immune function, nutrient allocation, and behavior (2). Squids are no exception in this regard. A particularly well-studied species is the bobtail squid Euprymna scolopes, which lives in a symbiotic relationship with light-producing Vibrio fischeri (3). Soon after hatching, the squid secretes mucous from a superficial epithelial field of cells. V. fischeri is selected in this mucus matrix as the sole symbiont, against the background of other environmental bacteria, before it moves into the light organ (LO) where it resides throughout the life of the host. The bacteria provide luminescence as a camouflage mechanism for their night-active hosts (4). The association between E. scolopes and V. fischeri offers a rich set of opportunities to study many aspects of symbiosis, from ecology and evolutionary biology to the molecular mechanisms underlying establishment and maintenance of a symbiotic association (5⇓–7) (Fig. 1) to the role of symbionts in driving host circadian rhythms (8). In addition to the LO, the bobtail squid uses, like some other cephalopods, an accessory nidamental gland (ANG), a female-specific organ associated with reproduction, for hosting bacterial symbionts. In contrast to the LO, which is colonized by multiple strains of a single bacteria species (V. fischeri), a more complex consortium of bacterial phylotypes colonizes the ANG, presumably to protect the eggs (9, 10).

Optimally designed ecological adaptations were placed into the context of: Bacterial Quorum-Sensing Network Architectures (8/17/09)

We argue that the Vibrio quorum-sensing systems are optimally designed to precisely translate extracellular autoinducer information into internal changes in gene expression. We describe how studies of the V. harveyi and V. cholerae quorum-sensing systems have revealed some of the fundamental mechanisms underpinning the evolution of collective behaviors.

No experimental evidence of top-down energy-dependent effects on organized genomes has ever been linked to the evolution of collective behaviors. The claims about extracellular autoinducer information obfuscate the fact that the light-activated assembly of the nucleic acid-microRNA-peptide nanocomplex link the creation of sunlight to internal changes in gene expression across kingdoms. Unfortunately, theorists tried to place the facts about nutrient-dependent pheromone-controlled quorum-sensing in bacteria back into the context of the evolution of organized genomes.

See: Symbiotic organs shaped by distinct modes of genome evolution in cephalopods (2/19/19)

Our findings suggest that the two symbiotic organs within E. scolopes originated by different evolutionary mechanisms. Transcripts expressed in these microbe-associated tissues displayed their own unique signatures in both coding sequences and the surrounding regulatory regions. Compared with other tissues, the light organ showed an abundance of genes associated with immunity and mediating light, whereas the ANG was enriched in orphan genes known only from E. scolopes. Together, these analyses provide evidence for different patterns of genomic evolution of symbiotic organs within a single host.

The ‘evidence’ from theorists and other pseudoscientists now collectively suggests that the light organ of a model cephalopod and a female-specific organ, which is associated with reproduction, in the same model cephalopod, evolved simultaneously.

Serious scientists will no doubt claim that the creation of two functional organs in the same animal represents what most intelligent people would attribute to food energy-dependent pheromone-controlled reproduction and sympatric speciation in species from microbes to cephalopod molluscs and mammals.

For comparison, the pseudoscientists and theorists are not likely to ever link the One-step co-assembly method to fabricate photosensitive peptide nanoparticles for two-photon photodynamic therapy (2/8/19) from the creation of sunlight to  Peptides as Quorum Sensing Molecules via the pheromone-controlled physiology of reproduction in bacteria despite the fact that “…the amount of autoinducer in the external environment reaches a certain level and triggers the production of the enzyme luciferase resulting in bioluminescence” in the model cephalopod mollusc.

That is why pseudoscientists failed to link bioluminescence to the production of antibiotics, the formation of biofilms, and and production of virulence factors in bacteria. Pseudoscientists cannot understand the fact that viruses in the bacteria cause the virulence. They cannot understand how researchers in Israel will use what they know about the virus-driven degradation of messenger RNA to cure cancer in the context of Retrodents: A transposon-driven burst of evolution in mice 7/30/18 and this claim Algae suggest eukaryotes get many gifts of bacteria DNA (2/1/19)


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