Kohl and Francoeur at 25 (3)
(click to enlarge)
Bacteriophages promote bacterial infection by directly triggering a maladaptive anti-viral immune response. In the absence of nutrient-dependent pheromone-controlled physiology of reproduction in bacteria the virus-driven degradation of messenger RNA is linked to all pathology in species from microbes to humans via the Virus-mediated archaeal hecatomb in the deep seafloor for comparison to the link to healthy longevity via Eukaryotic plankton diversity in the sunlit ocean.
Someone wrote:
“…this paper shows it will be important to see if this phenomena extends to lytic phage which are preferred for phage therapy over temperate phage like these. More studies of how phage interact with the immune system are definitely needed!
More than 84,000 studies of energy-dependent microRNA-mediated cell type differentiation detail the interactions across species from microbes to humans in the context of what was presented as science fiction in 1999 and 2003. See: Reactivation of a dormant message signals the dawn of a new humanity (1999) and Living with the Neanderthals (2003)
Someone else wrote:
Agreed! I am extremely excited to see the increase in research regarding the interactions between phages and the immune system. Definitely an important hurdle in phage therapy research
I responded :
You have earned the title of ‘total snow flake’ by ignoring the extant literature that links the light-activated assembly of the microRNA-RNA-peptide #nanocomplex to biophysically constrained viral latency via the weekend resurrection of the flagellum in P. fluorescens.
Difference in the role that P. aeruginosa plays as an opportunistic human pathogen compared to the plant pathogen P. syringae , and the soil bacterium P. putida link the light-activated assembly of the miRNA-RNA-peptide-nanocomplex to the weekend resurrection of the bacterial flagellum in the plant growth-promoting P. fluorescens via fixation of two amino acid substitutions.
See: Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system
Reported as Life finds a way
VIDEO
The amino acid substitutions that are linked to the weekend resurrection of the bacterial flagellum are referred to as mutations, and few people realize what that means. It means that the evolution of a functional structure with irreducible complexity occurred within 96 hours. More importantly, it occurred via what is known to all serious scientists about links from light to plant growth and the growth of food to the pheromone-controlled physiology of reproduction in species from microbes to humans.
See: The Viruses That Eavesdrop on Their Hosts
The viruses/bacteriophages/phages are biophysically constrained by the creation of:
1) anti-entropic virucidal light
2) ATP
3) enzymes
4) microRNAs
5) RNA
6) amino acids
7) peptides
8) the immune system in bacteria
and
9) the immune system of mammals
See also: Really cool mechanism of a #temperate #phage interacting with the mammalian immune system. Look forward to see the next story! Important to note that many pathogens encode prophages contributing to virulence (less exotic mechanisms). Very rich history in Salmonella for example.
The ability of biologically uninformed theorists to link everything known about biophysically constrained viral latency to the immune system of mammals and then change the focus from the history of Pseudomonas to the history of Salmonella exemplifies human idiocy.
See for comparison: Learning from Bacteria about Natural Information Processing
Schrodinger focusing on ecological variation in the energy, matter, and thermodynamic imbalances. He proposed that life required the consumption of energy, but used the term negative entropy. Consumption requires information processing systems and at least two thermodynamic elements. The outer membrane of the cell must sense the environment before the cell can extract energy as information. Until the information is extracted it is latent embedded information.
By latent information we refer to data embedded in the environment that, once processed cognitively, initiates change in the organism’s function or behavior. Information induces changes; hence it can be used to generate an internal condensed description (model or usable information) of the environment, which guides the organism’s functioning.
By removing the context of energy as information that biophysically constrains viral latency, the authors of Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection take us back to a time when the definition of mutation began to replace the creation of sunlight (energy as information) as the link from fluorescence in P. fluorescens to plant growth and from what organisms eat to their pheromone-controlled physiology of reproduction and healthy longevity via the transgenerational epigenetic inheritance of all morphological and behavioral phenotypes.
See also: This Week in Photonics: Mediating Quantum Information Exchange; Levitating Objects with Light; More (3/28/2019)
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4 MIN READ
0
2018 March for Science vs microRNAs
7 MIN READ
0
The eternal significance of microRNAs (1)
< 1 MIN READ
0
Sympatric Speciation vs pseudosceintific nonsense (4)
2 MIN READ
0
Complexity: Routes and Patterns (4)
< 1 MIN READ
0
RNA-mediated nutritional psychiatry (2)
2 MIN READ
0
RNA-mediated nutritional psychiatry
4 MIN READ
0
Nick Lane refutes theistic evolution (1)
5 MIN READ
0
Polymaths and paradigm shifts: From Asimov to Bear (5)
5 MIN READ
0
Polymaths and paradigm shifts: from Asimov to Bear (1)
5 MIN READ
0
Carl Zimmer refutes theistic evolution (2)
2 MIN READ
0
Ecological adaptation: A new definition of heredity (3)
4 MIN READ
0
Creating biophysically constrained viral latency (2)
2 MIN READ
0
Light-activated carbon fixation did not evolve (4)
7 MIN READ
0
How to biophysically constrain the flu virus (1)
4 MIN READ
0
Cryo-EM: Linking spatial and conformational constraints
9 MIN READ
0
A reversible TCA cycle in a thermophile (3)
4 MIN READ
0
A mental health problem at the highest level (3)
7 MIN READ
0
Diet-driven RNA interference and mental health (3)
4 MIN READ
0
Anti-entropic sunlight: Schrödinger’s Creationist Secret? (3)
6 MIN READ
1
Anti-entropic sunlight: Schrödinger’s Creationist Secret? (2)
4 MIN READ
0
BiondVax Universal Flu Vaccine Patent
4 MIN READ
0
The MicroRNAome Strikes Back: A Sokalian hoax (5)
6 MIN READ
0
The MicroRNAome Strikes Back: A Sokalian hoax (3)
4 MIN READ
0
The MicroRNAome Strikes Back: A Sokalian hoax (2)
6 MIN READ
0
A mental health problem at the highest level (2)
3 MIN READ
0
Diet-driven RNA interference and cancer prevention (3)
6 MIN READ
0
Enzyme-constrained interethnic diversity (8)
< 1 MIN READ
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Enzyme-constrained interethnic diversity (7)
6 MIN READ
0
Enzyme-constrained interethnic biodiversity (1)
5 MIN READ
0
The “walking fish” walks straight from quantum physics to quantum souls (4)
11 MIN READ
0
The “walking fish” walks straight from quantum physics to quantum souls (2)
3 MIN READ
0
A Mathematical Model Links Quantum Physics to Quantum Souls (1)
6 MIN READ
0
From base editing to RNA editing (6)
8 MIN READ
0
Darwinian adaptation: a clear evolutionary trail?
4 MIN READ
0
Agilent technology and energy-dependent autophagy
8 MIN READ
0
Narcissistic egomaniacal and deadly denial of autophagy
6 MIN READ
0
The overwhelming ignorance of sex researchers (2)
4 MIN READ
0
Energy-dependent base editing and correction of mutations (2)
9 MIN READ
0
Trashing the 2nd Law
7 MIN READ
0
The overwhelming ignorance of sex researchers
5 MIN READ
0
Two retractions of human idiocy
2 MIN READ
0
Reporting new scientific truths is not allowed in the USA
3 MIN READ
0
MicroRNAs and the Cassandra syndrome (revisited)
4 MIN READ
0
A null mutation and healthy longevity?
4 MIN READ
0
Light-activated error free DNA repair
5 MIN READ
0
Achromobacter and killer theories
2 MIN READ
0
Eutrophication and phosphorylated biodiversity
6 MIN READ
0
The next reformation: 500 years too late? (1)
< 1 MIN READ
0
The next reformation: 500 years too late? (2)
2 MIN READ
0
From base editing to RNA editing (2)
7 MIN READ
0
Cryo-EM: More than a suggestion
< 1 MIN READ
0
Exome Sequencing Impact in Routine Care
4 MIN READ
0
Virulence: Out of stock
2 MIN READ
0
Energy-dependent structure and function: Until death (5)
4 MIN READ
0
Entertaining yourself to death
6 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (2)
4 MIN READ
0
Sci-Hub vs limits on the dissemination of information
6 MIN READ
0
Evolutionary theories of epigenetic drift
2 MIN READ
0
Host-derived creation of all pathology (2 of 2)
9 MIN READ
0
God vs host-derived creation of virus-driven pathology
6 MIN READ
0
Your indifference is killing you and others (4)
4 MIN READ
0
Robert Sapolsky’s legacy of atheistic pseudoscientific nonsense
4 MIN READ
0
Energy-dependent physical and biophysical constraints (10)
8 MIN READ
0
God’s shrinking role in salvation (2)
5 MIN READ
0
MicroRNAs light up life
7 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models (5)
5 MIN READ
0
Food energy-dependent epigenetic adaptation (2)
< 1 MIN READ
0
The Virus-Driven Suicide March for Science
5 MIN READ
0
Viruses in pathogenic variants disrupt alternative splicings (2)
3 MIN READ
0
Respiration-dependent endogenous RNA interference
4 MIN READ
0
Food for thought: Penrose v Ellis (3)
4 MIN READ
0
Magnussen’s “Faith fools” keep the faith
3 MIN READ
0
The essence of precision medicine
4 MIN READ
0
Allen Institute confirms food energy is information
6 MIN READ
0
RNA-mediated adult learning, memory, and neurogenesis
3 MIN READ
0
Theistic evolutionists fight back and lose
4 MIN READ
0
Bill Gates refutes theistic evolution (sequel)
8 MIN READ
0
Bill Gates refutes theistic evolution
4 MIN READ
0
Happy Darwin Day (2017)
4 MIN READ
0
George Church refutes theistic evolution
5 MIN READ
0
Energy-dependent hydrogen bonds in supercoiled DNA
7 MIN READ
0
Energy-dependent chirality
6 MIN READ
0
Vietnam Veterans and others with glioblastoma
3 MIN READ
0
Energy-dependent sensory maps (1996-2016)
5 MIN READ
0
Re-inventing mutation-driven evolution (2)
4 MIN READ
0
Energy-dependent coulombic, autophagic, polycombic healthy longevity
4 MIN READ
0
Energy-dependent purifying selection / autophagy (3)
2 MIN READ
0
Energy-dependent purifying selection / autophagy
2 MIN READ
0
Epigenetically effected energy-dependent fluorescence
5 MIN READ
0
80 years of causal analysis (1936 – 2016)
11 MIN READ
0
The natural success of RNAi and failed treatment
7 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
How did the innate immune system evolve?
4 MIN READ
0
The Aquatic Ape: New evidence?
4 MIN READ
0
Protecting 4 billion people from virus-driven entropy
< 1 MIN READ
0
Lawless evolution: No physics
4 MIN READ
0
Antithetical conclusions (7)
3 MIN READ
0
RNAi: From magic bullet to billion dollar baby
4 MIN READ
0
GC-rich neo-Darwinian train wreck
5 MIN READ
0
From angstroms to ecosystems
7 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
The end of neo-Darwinism
5 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity
4 MIN READ
0
Did “Nature” kill Steve Jobs? (3)
10 MIN READ
0
Did “Nature” kill Steve Jobs? (2)
6 MIN READ
0
Did “Nature” kill Steve Jobs?
3 MIN READ
0
Placing boundaries where none exist
< 1 MIN READ
0
Innate immunity and multiplexing
7 MIN READ
0
RNA methylation (2)
7 MIN READ
0
Masters of deception about nature (2)
7 MIN READ
0
Cracking the Olfactory Code?
5 MIN READ
0
Energy-dependent RNA methylation (9)
2 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (6)
9 MIN READ
0
Energy-dependent RNA methylation (5)
3 MIN READ
0