Genetic endemism: apologetics vs epigenetics (2)

By: James V. Kohl | Published on: July 8, 2019

Genome-Wide Study Reveals a Novel Regulatory Pathway: Translation Affects mRNA Stability in a Codon-Dependent Manner (6/26/19)
Ariel Bazzini supports claims of nutrient-dependent pheromone-controlled ecological adaptations that eliminate the pseudoscientific nonsense touted by neo-Darwinian theorists.
Bazzini indirectly links the creation of sunlight from
1) the creation of ATP
2) to the creation of RNA,
3) to the creation of endogenous substrates called microRNAs,
and
4) to RNA interference, which biophysically constrains viral latency.
For comparison, see: Wallaceโ€™s World: Darwin in reverseโ€”From natural selection to natural theology? (7/2/19)
Wallace presciently argued for the current scientific truth that humans had a single origin, not the nonsense about origins in more than one place and time.
See for example Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk (4/23/18)

The frequency of the human-specific EDAR V370A allele appears to be uniquely elevated in North and East Asian and New World populations due to a bout of positive selection…

The single origin perspective also was supported in: Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants, which was reported as: Past 5,000 years prolific for changes to human genome

The findings confirm their earlier work suggesting that the majority of variants, including potentially harmful ones, were picked up during the past 5,000โ€“10,000 years.

For comparison, Masatoshi Nei and a biologically uninformed antagonist, Jay R. Feierman followed neo-Darwinian theory to its nonsensical end by eliminating the teleological elements that all serious scientists linked from Darwin’s “conditions of life” to natural selection for energy-dependent codon optimality.
See: Mutation-Driven Evolution (6/14/13) and my refutation of their pseudoscientific nonsense in Nutrient-dependent/pheromone-controlled adaptive evolution: a model (6/14/13)

See for comparison:
Jay R. Feierman:

Variation is not nutrient availability and the something that is doing the selecting is not the individual organism. A feature of an educated person is to realize what they do not know. Sadly, you donโ€™t know that you have an incorrect understanding [of] Darwinian biological evolution.

Jay R. Feierman:

I am absolutely certain that if you showed this statement to any professor of biology or genetics in any accredited university anywhere in the world that 100% of them would say that โ€œRandom mutations are the substrate upon which directional natural selection actsโ€ is a correct and true statement.

The virus-driven degradation of messenger RNAย  links mutations to all pathology. That fact has been placed into the context of what is known to all serious scientists, since Wallace, about the forthcoming cure for cancer and brain dysfunctions.
All serious scientists know that the virus-driven pathology is biophysically constrained by epigenetic effects on feedback loops that link food odors and pheromones to healthy longevity.
As an aside, Wallace reportedly ‘flirted’ with the ideas of spiritualism and opposition to vaccination.

Nei eliminated spiritualism with his claim that in his view of evolution there was no need to consider teleological elements: Darwin’s “conditions of life.”

The Last Temptation: How evangelicals, once culturally confident, became an anxious minority seeking political protection from the least traditionally religious president in living memory

Protecting Christianity, Trump essentially argues, is a job for a bully.

Indeed, most evangelicals have been running and hiding from the facts of life. When the facts are ignored, the claims of serious scientists turn some humble apologists into bullies who beat back their antagonists with facts about natural selection for energy-dependent codon optimality.
See also the confirmation of Bazzini’s presentation claims about natural selection for energy-dependent codon optimality in:
The AMPK system of salmonid fishes was expanded through genome duplication and is regulated by growth and immune status in muscle (7/8/19)

…when…ATP levels are low, AMPK is activated, leading to stimulation of pathways that produce ATP…

Those pathways link the light-activated assembly of the microRNA-RNA-peptide nanocomplex to biophysically constrained viral latency.
See: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of โ€œoxidative phosphorylationโ€ (1964)

The synthesis of RNA in isolated thymus nuclei is ATP dependent.

If you failed to link the creation of anti-entropic virucidal light to all biodiversity via the physiology of reproduction in species from microbes to humans, see this for comic relief:

Remember that all serious scientists are laughing at you. It’s past time to learn why. Start with the claims of Alfred Russel Wallace and move away from the claims of neo-Darwinian theorists. They are pseudoscientists who failed to link the creation of sunlight to all biodiversity on Earth via the physiology of reproduction.


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