Sunlight, hydrophobicity and biodiversity (3)

By: James V. Kohl | Published on: August 13, 2019

Ed Yong sneaks up from behind with A New Clue to How Life Originated 8/12/19

Mice hint at how people’s emotional trauma may affect the biology of their children—and their children’s children.

The article recapitulates the claims made about how energy-dependent changes in angstroms to ecosystems in all living genera biophysically constrain viral latency. The scent of a predator is linked to the development of spiky, armored heads in water fleas. But the detailed links from food odors and pheromones to the physiology of reproduction and all morphological and behavioral phenotypes in species from microbes to humans are buried in the commentaries by experts. Some of them know that the deleterious epigenetic changes are reversible.
That means other researchers are deliberately avoiding telling the masses about food energy-dependent pheromone-controlled biophysical constraints on changes in base pairs linked to the EDAR V370A amino acid substitution in the mouse to human model of how sunlight is linked from hydrophobicity in supercoiled DNA to all biodiversity.
See: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18 and Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk 4/23/18

The frequency of the human-specific EDAR V370A allele appears to be uniquely elevated in North and East Asian and New World populations due to a bout of positive selection…

The positive selection was linked from naturally occurring RNA interference (RNAi) to the prevention of all virus-driven pathology in this patent.
RNA-Guided Human Genome Engineering 

5. Repetitive elements or endogenous viral elements can be targeted with engineered Cas+gRNA systems in microbes, plants, animals, or human cells to reduce deleterious transposition or to aid in sequencing or other analytic genomic/transcriptomic/proteomic/diagnostic tools (in which nearly identical copies can be problematic).

The patent application was the subject of Get Well in the RNAi Way-RNAi, A Billion Dollar Baby in Therapy (2015)

The technique of gene silencing also called as RNA interference (RNAi) keeps our hopes alive….

 Apart from the delivery, the design, stability and degradation of RNAi based effective molecules appears to be the major lime light to challenge the conventional drug safety concerns and ensures to be the most powerful gene recovery in future which execute billion dollar business hope.

First RNAi Therapy Approved by FDA 8/10/18

By infusing lipid nanoparticles filled with short interfering RNAs into the liver, transcripts for the aberrant protein are blocked from translation.

Remember: Prebiotic amino acids bind to and stabilize prebiotic fatty acid membranes was published on 8/12/19, which was the same day that Ed Yong ignored everything known to serious scientists about biophysically constrained viral latency in A New Clue to How Life Originated.
He, and others like him, have also ignored this fact from Past 5,000 years prolific for changes to human genome 11/28/12

The findings confirm their earlier work suggesting that the majority of variants, including potentially harmful ones, were picked up during the past 5,000–10,000 years.

That fact links natural selection for food energy-dependent pheromone-controlled codon optimality to biophysically constrained healthy longevity in species from microbes to humans without inventing more pseudoscientific nonsense about how we evolved from bacteria during the past 3.5 to 4 billion years.
See also: Genome-Wide Study Reveals a Novel Regulatory Pathway: Translation Affects mRNA Stability in a Codon-Dependent Manner (video) 6/26/19

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