The tipping point (revisited) 90K (4)

By: James V. Kohl | Published on: August 20, 2019

Three recently published articles sow the seeds of discontent linked to the social media storm of complaints about celebrity pseudoscientist, Neil deGrasse Tyson.
Could the Big Bang be Wrong? 6/15/19
New tactics clash on speed of expanding universe 7/26/19
Twitter slams Neil deGrasse Tyson for ‘tasteless’ tweet about mass shootings: ‘Lost all respect for you 8/4/19
Energy-dependent biophysically constrained viral latency was linked from the sense of smell in bacteria to our visual perception of energy and mass across the time space continuum in Olfaction Warps Visual Time Perception 3/17/17
Everything known to serious scientists about the light-activated creation of microRNAs and the role they play as the endogenous substrates that link what organisms eat to healthy longevity across kingdoms has been bastardized via the tactical use of terms and misrepresentations of energy-dependent top-down causation.
For example, The concept of QTLs has been overhyped by biologically uninformed theorists since the time that microRNAs were referred to as pre-mRNAs in our 1996 review of RNA interference, which biophysically constrains viral latency.
See: From Fertilization to Adult Sexual Behavior (1996)
See for comparison: GWAS hints at pleiotropic roles for FLOWERING LOCUS T in flowering time and yield-related traits in canola 8/6/19

Complementary QTL and eQTL mapping studies, conducted in an Australian doubled haploid population, also detected consistent genomic regions close to the FT paralogs associated with flowering time and yield-related traits.

For comparison: Ecologically relevant mating cues (sometimes known as “magic traits” [2,6]) are now predicted to be widespread in nature [6,7], and the last few years have seen considerable progress in our understanding of their genetic basis. 2/17/19
See also: A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers 8/8/19
While Mediator plays a key role in eukaryotic transcription, little is known about its mechanism of action.
The creation of anti-entropic virucidal light is the microRNA-mediated “Mediator,” and all serious scientists know it.
See: Eukaryotic plankton diversity in the sunlit ocean 5/22/15

Diversity emerged at all taxonomic levels… and among twice as many other deep-branching lineages of unappreciated importance in plankton ecology studies. Most eukaryotic plankton biodiversity belonged to heterotrophic protistan groups, particularly those known to be parasites or symbiotic hosts.

The fact that sunlight biophysically constrains viral latency links the energy-dependent pheromone-controlled physiology of reproduction to sympatric speciation in all hosts.
But see: Enhancer Features that Drive Formation of Transcriptional Condensates 8/8/19

Enhancers are DNA elements that are bound by transcription factors (TFs), which recruit coactivators and the transcriptional machinery to genes.

Reported as: Study furthers radically new view of gene control 8/8/19

“This study provides a fundamentally important new approach to deciphering how the ‘dark matter’ in our genome functions in gene control,” says Richard Young, an MIT professor of biology and member of the Whitehead Institute.

I reiterate: Kepler’s Forgotten Ideas about Symmetry Could Explain Spiral Galaxies Without the Need for Dark Matter 8/8/19
The fact that no “dark matter” has ever been found suggests claims that it is involved in gene control makes the physicists, chemists and molecular biologists appear to be fools if they have not yet linked the sun’s anti-entropic virucidal energy from the physiology of reproduction to all biodiversity. It is time to ask the so-called experts:

  1. What is the difference between complementary QTLs and eQTLs…
  2. …for comparison to the role that “Mediator” plays a key role in eukaryotic transcription?
  3. How do the DNA elements called enhancers drive the formation of supercoiled DNA, which protects all organized genome from the virus-driven degradation of messenger RNA?
  4. Why was the term non-homologous end joining invented after all serious scientists had linked alternative splicings of pre-mRNAs (aks microRNAs) to all biodiversity on Earth via the physiology of reproduction and naturally occurring RNA interference?

Further attempts to bury the answers in articles like this one should be met with contempt.

Comprehensive scanning mutagenesis of human retrotransposon LINE-1 identifies motifs essential for function 8/6/19

We provide comprehensive information on the regions most critical to retrotransposition. This resource will guide future studies of intermolecular interactions that form with RNA, proteins and target DNA throughout the L1 life cycle.

ICYMI: All functional structures are energy-dependent at every level of biological organization. Viruses steal the energy. See All about that base.
See: These two photos (taken 12-hours apart on 8/7/19) link the sun’s anti-entropic virucidal energy to biophysically constrained viral latency in all living genera via microRNA-mediated controlled changes in QTLs. They allow you to compare the Americanism background to Australianism

On 8/8/19, I gave Ethan Siegel the chance to apologize for his displays of overwhelming ignorance, which led to claims about dark energy in organized human genomes. That pseudoscientific nonsense links his pseudoscientific nonsense from the virus-driven degradation of messenger RNA to mass killings and suicides via energy-dependent changes in one base pair and one amino acid substitution, COMT Val158Met. The viruses steal the energy, which is the cause of all diseases.
James Kohl: Waiting for you to admit how wrong you have been about “dark matter.”
Starts With A Bang Do your trolling elsewhere, James. I do not exist for you to take your anger out on
See for comparison: Feynman on food energy  (video) and The Dynamical Emergence of Biology From Physics: Branching Causation via Biomolecules

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