Chemogenetic kinetics (7): DHA vs consensus (4)

By: James V. Kohl | Published on: September 30, 2019

Mammalian Y RNAs are modified at discrete guanosine residues with N-glycans 9/30/19

…mammalian cells use RNA as a third scaffold for glycosylation in the secretory pathway.

…RNA glycosylation depends on the canonical N-glycan biosynthetic machinery within the ER/Golgi luminal spaces.

…these findings suggest the existence of a ubiquitous interface of RNA biology and glycobiology suggesting an expanded role for glycosylation beyond canonical lipid and protein scaffolds.

Facts about glycosylated RNA can be linked to detailed mechanisms of how Peroxiredoxin 1 Protects Telomeres from Oxidative Damage and Preserves Telomeric DNA for Extension by Telomerase 1/20/16

The detailed mechansims were reported as: Aging and cancer: An enzyme protects chromosomes from oxidative damage 12/20/16

EPFL scientists have identified a protein that caps chromosomes during cell division and protect them from oxidative damage and shortening, which are associated with aging and cancer.

The Creation of the enzyme, which was reported as if it was like other proteins, except that it protects chromosomes from oxidative damage was presciently presented in the context of McEwen et al., (1964)

Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation”

The synthesis of RNA in isolated thymus nuclei is ATP dependent.

The connection from the Creation of the sun’s anti-entropic virucidal energy on contact with water to the physiology of reproduction via the light-activated assembly of the microRNA-RNA-peptide nanocomplex should be perfectly clear. Enzymes do not create themselves. That fact makes all other claims made by biologically uninformed science idiots the target for ridicule by all molecular biologists.

The findings of this trial indicate an association between short-term change in LTL [Leukocyte Telomere Length] and concomitant change in plasticity of the left precuneus extending to the posterior cingulate cortex. This result contributes to the evidence that LTL changes more dynamically on the individual level than previously thought.

Reported as: Cellular aging is linked to structural changes in the brain 9/26/19

“Across systems, our biological aging appears to change more quickly than we thought. Indices of aging can vary together significantly in just three months,” says Puhlmann. If the telomeres changed in length, this was associated with structural changes in the brain. In a period when participants’ telomeres lengthened during the study, it was also more likely that their cortex had thickened at the same time. On the other hand, telomere shortening was associated with reductions of gray matter. This association occurred specifically in a brain region called the precuneus, which is a central metabolic and connectional hub.

Viruses steal the energy that cell types need to link differentiation from the central metabolic and connectional hub to the functional structure of the brain. Ridiculous claims about mutation-driven evolution and global warming can be placed into the context of already dysfunctional brains in the skulls of theorists.

Simply put, the snake-centric theory of functional primate brain evolution has not been supported, but

Isbell calls these findings “the first neuroscientific support” for her snake-centric evolutionary theory.

For comparison, there is support for claims about how the dysfunctional brains of theorists developed.

See: Projected declines in global DHA availability for human consumption as a result of global warming 9/12/19

Docosahexaenoic acid (DHA) is an essential, omega-3, long-chain polyunsaturated fatty acid that is a key component of cell membranes and plays a vital role in vertebrate brain function. The capacity to synthesize DHA is limited in mammals, despite its critical role in neurological development and health.

They linked the virus-driven degradation of cell membranes from cells in the brain to archaea and L-forms, which are the last vestiges of energy-dependent biophysically constrained Creation.

The question arose:

Do we know which amino acids or conditions that support or enhance their growth/production?

I said: Yes. Changes in the link viral replication from the degradation of messenger RNA to all pathology via the transgenerational epigenetic inheritance of mutations caused by amino acid substitutions in viruses that prevent cell type differentiation in all cell types.

See for comparison:

There’s so much to learn with this new technology too being that viruses are 10x all other living things on this snow globe called earth!!

I wrote: That claim is common among biologically uninformed science idiots who have failed to follow the extant literature that led to this presentation by Nobel Laureate (chemistry) Bernard Feringa. The Future of Chemistry – Schrödinger at 75:The Future of Biology
Amy Proal @microbeminded2 wrote:

James you’re first person on here I’m going to block. Your comments are confusing people and have nothing to do with my actual research

I wrote: Thanks. I get that a lot. Each time I expose someone who has fallen behind the extant literature on energy-dependent biophysically constrained viral latency via RNA interference, they tend to run away and hide by blocking me. I saw this coming from you starting a few weeks ago.
I added: Had @microbeminded2 learned what @microRNApro knows about biophysically constrained viral latency, she would not be forced to hide from the facts and make claims about the importance of so-called new findings.
See: