#SFN2019 to 2012: Hiding the facts (2)
(click to enlarge)
Polycomb repressive complex 1: Regulators of neurogenesis from embryonic to adult stage extends our 1996 claims in From Fertilization to Adult Sexual Behavior to all ethnic diversity in morphology and behavior via alternative splicings of pre-mRNAs.
The term use began to change from pre-mRNAs to microRNAs. I learned that from the abstract of a presentation at SFN 2012, and followed up on the presentation with others who were presenting posters that mentioned microRNAs.
I had already presented during the 2012 ancillary meeting of the Society for Social Neuroscience Presentation. That is why the term microRNA interested me. I asked if microRNAs were the link to all downstream effects on cell type differentiation, and the speaker said “That’s what we have learned during the past ten years.”
See why that fact is important. This is what I presented in 2012:
Poster A15, Thursday, October 11, 6:30 – 8:00 pm, Grand Ballroom D, Hilton Riverside Hotel
Human pheromones and nutrient chemicals: epigenetic effects on ecological, social, and neurogenic niches that affect behavior.
Background: The 2007 iteration of the FDA Critical Path Initiative (FDACPI) is a systems biology approach to disease prevention and pharmacogenomics. It stresses the need to examine healthy behavioral development by including interactions among the evolved gene, cell, tissue, organ, organ-system pathway. This pathway links the epigenetic effects of nutrient chemicals and pheromones directly to the organization and activation of behavior in species from honeybees to humans.
The 2011 American Society of Addiction Medicine (ASAM) Public Policy Statement: Definition of Addiction dictates the integration of the FDACPIs neuroscientific principles of epigenetic cause and effect, which are required to understand differences between genetically predisposed brain disease, naturally occurring variations of behavioral development, and choice. These neuroscientific principles include focus on how sensory input influences behavior.
ASAM specifically mentions food and sex along with drugs and alcohol. Each of these influences chemically conditions changes in hormones and in behavioral responses.
Study design: Nutrient chemical signals are associated with food odors. Pheromones are chemical signals associated with social odors and sex differences. We incorporated what is currently known about the ability of chemical signals to condition behavior. This conditioning occurs via epigenetic effects that calibrate and standardize the molecular biology of intracellular signal transduction and stochastic gene expression, which controls the feedback loops of developmental processes required for movement, ingestion, reproduction, and the diversification of species from microbes to man.
Method: Pre-existing, adaptively evolved, nutrition dependent, hormone-driven, cyclic peak fertility in fourteen women was assessed by a non-invasive measure of luteinizing hormone (LH). During a double-blind social construct, the women were exposed for fifteen minutes to a man who had applied either a control mixture (n=7), or a mixture of androstenol/androsterone (n=7). Both mixtures contained the same masking odor. Summary: Evaluated video recordings of interactions showed increased flirtatious behaviors of women, which were statistically attributed to the effect of androstenol on LH and the unconscious affect of androsterone. Measures of self-reported increased attraction correlated with the increased flirtatious behaviors.
Conclusions: Across species comparisons of epigenetic effects on nutrition dependent and hormone-driven invertebrate and vertebrate social and sexual behavior indicate that the androstenol/androsterone mixture contains pheromones, which may increase opportunities for properly timed reproductive sexual behavior. Neuroscientifically established epigenetic effects of sensory input on hormones that affect behavior suggest that this mixture of human pheromones causes changes in ecotypically organized neural pathways that directly link nutrient chemicals and social niches to 1) neurogenic niches; 2) the molecular biology of evolved neural circuitry; 3) genetically predisposed physiological changes, and to 4) unconscious affects on behavior in species from invertebrates to mammals. The molecular biology is conserved and transgenerational epigenetic inheritance establishes the pre-existing genetic variation. Our results tentatively extend epigenetic effects on intracellular signaling, gene expression, hormones, and unconscious affects on behavior, which are due to food odors and pheromones in insects, to socioaffective neuroscience in people despite pre-existing genetic variation and phenotypic differences in nutrition dependent hormone-driven development of the brain, and differences in the development of social and sexual behaviors.
Summary of our facts about human pheromones:
It subsequently became clear that microRNAs were the link from pre-existing genetic variation to all phenotypic differences in the nutrient-dependent hormone-driven development of the brain, and differences in the development of social and sexual behaviors.
Food energy-dependent pheromone-controlled biophysically constrained viral latency has since been linked from the light-activated assembly of the microRNA-RNA-peptide nanocomplex to every aspect of biodiversity across kingdoms.
Obfuscaton
What happened with the term pre-mRNA when it was changed to microRNA obfuscated pattern recognition with use of older non-descriptive terms such as ‘polycomb repressive complex’ instead of ‘microRNA-RNA-peptide nanocomplex’ which has also been referred to as the ‘Skp1/cullin/F-box (SCF) complex.’
The different names for the same nanocomplex have been linked to healthy longevity or to cancer via use of the terms such as ‘spasmolytic polypeptide-expressing metaplasia’ in the context of transthiolation, a fundamental biological reaction that is utilized by many enzymes such as the light-activated ubiquitin-conjugating enzyme, cdc34.
But, only the names have changed. The facts link light-activated microRNA biogenesis from the Creation of enzymes to all biodiversity on Earth. MicroRNA biogenesis is required to biophysically constrain viral latency, which is required for the genesis of all biophysically constrained biodiversity.
I reiterate. For confirmation of the facts, which have not changed, see these presentations during the 2019 Annual Meeting of the Society for Neuroscience
683.03. Hypothalamic microRNA-7 regulates energy homeostasis in vivo
552.08. MicroRNA regulation of inhibitory synaptic plasticity
642.23. Behavioral characterization of mice deficient for the mammal-specific microRNA 379-410 cluster
649.08. Profiling of neuronal and microglial argonaute-2 bound microrna during epileptogenesis and in chronic epilepsy reveals cell-type specific contribution to disease
036.07. Regulation of brain synapses and behaviour by miR-138
734.26. Unique blockage of host RNAi machinery by the zika virus capsid in fetal NSCs and mouse model
076.22. A rodent model of early life stress (ELS) associated with altered miRNA expression in rat hypothalamus
126.20. Specific microRNAs (miRNAs) play major roles in human diseases
236.07. Profiling brain-derived exosomes in the prefrontal-cortex of individuals with major depressive disorder
602.01. Odor preference training in week-old rat pups is associated with changes in protein and non-protein coding messenger ribonucleic acids in odor-encoding mitral cells
602.05. Synaptogenesis and neuronal activation dependent on MeCP2/CaMK2A phosphorylation signaling pathway
640.12. Micrornas and histone deacetylase inhibition mediated differentiation of human mesenchymal stem cells into neuronal lineage
704.03. Isoform analysis of blood transcriptomic biomarkers for depression in human lymphocytes and hippocampal tissue
628.04. Programmable modulation of extracellular vesicles
736.15. Spatio temporal dynamics of miRNA mediated regulation of local protein synthesis
and
776.21. Blood microRNAs as biomarkers for stress susceptibility or resiliency and treatment response
In Patented Creation vs Evolution of Disease (9), I wrote
For the historical perspective on works from E. J. NESTLER, see: Transgenerational Epigenetic Contributions to Stress Responses: Fact or Fiction? 3/25/16
Despite the two extremes of disbelief versus wild speculation, there is growing evidence for at least some contribution of epigenetic regulation—perhaps achieved by miRNAs—in mediating part of the ability of parental behavioral experience to influence stress vulnerability in their offspring.
Growing evidence has turned into overwhelming evidence that energy-dependent biophysically constrained microRNA-mediated viral latency is required for the the transgenerational epigenetic inheritance of healthy longevity.
The take home message from the 2019 Annual Meeting of the Society for Neuroscience should be something the helps biologically uninformed theorists and other science idiots accept the facts that link nutrient stress and or social stress to all pathology via the works of Bruce S. McEwen.
Moving forward. See: Bruce McEwen et al.
018.08. Role of the ventral hippocampal circuit in generating and regulating cognitive responses to stress and a novel antidepressant
The ventral hippocampal circuit has emerged as a target for the responses to stress and antidepressant action, including the rapid actions of the novel glutamatergic agent acetyl-L-carnitine (LAC). Previous research has shown that chronic stress causes bot…
240.27. Oxycodone injections not paired with conditioned place preference have little effect on the hippocampal opioid system in female and male rats
…changes in the hippocampal opioid system that would promote opioid-associative learning processes do not occur with administration of oxycodone alone, and instead must be paired with CPP.
240.28. Sex and chronic stress differentially alter phosphorylated mu and delta opioid receptor levels in the rat hippocampus following oxycodone conditioned place preference
240.29 / W1 – Sex differences in the mRNA expression of opioid peptides and receptors in the rat hippocampus
…sex-dependent changes in opioid-associated genes and receptors in the hippocampus following CIS are paralleled with an inability for males, but not females, to acquire conditioned place preference (CPP) to mu-agonist oxycodone. Here, RNAScope in situ hybridization was used to determine if the expression of hippocampal opioid peptides and receptors is altered in unstressed (US) and CIS estrus female and male rats.
293.04. Divergent roles of astrocytic versus neuronal glutamate transporter EAAT2 deficiency on cognition and overlap with aging and Alzheimer’s molecular signatures
594.22. What happens to the infant during maltreatment? Stress targets hippocampus but stress with mother targets amygdala and social behavior
675.16 / P5 – Individual differences in aggression mediated by temporal changes in cytokine signaling in the dorsal raphe nucleus
These data also supports an involvement of endogenous IL-1β in aggressive behaviors, however, the source of IL-1β in the dorsal raphe nucleus is still not clear and requires further investigation.
636.04 – Transcriptional profiling of the stressed hippocampus: Does sex make a difference?
This favors the use of big data to probe dissimilar gene functions that underlie sex-specific endophenotypes in animal models of stress.
769.02 / Q8 – Estrogen receptor beta agonists block slow-onset angiotensin II hypertension and reduce NMDA receptor-signaling in paraventricular neurons in female mice at an early stage of accelerated ovarian failure
These results suggest that heightened NMDA receptor signaling in ERβ-expressing PVN neurons contributes to the susceptibility of peri-AOF mice to the hypertensive actions of AngII. These findings provide preclinical evidence supporting a therapeutic window of opportunity for estrogen-based management of hypertension as women transition through menopause.
Want more on the same topic?
Swipe/Drag Left and Right To Browse Related Posts:
Biophotonically charged life (2)
2 MIN READ
0
Epistemic corruption (6)
4 MIN READ
0
RNAi 2002 to AI 2021 (9)
2 MIN READ
0
Orchestrated death: Aeon
2 MIN READ
0
Natural selection for adaptation (8)
4 MIN READ
0
microRNA-mediated election cycles (4)
4 MIN READ
0
Quantum biology vs atheism (2)
< 1 MIN READ
0
Quantum Darwinism (6)
2 MIN READ
0
Quantum Darwinism (3)
3 MIN READ
0
Life or death facts about theories (4)
3 MIN READ
0
Creationism, Communism and Corruption (2)
2 MIN READ
0
Creationism, Communism and Corruption (1)
2 MIN READ
0
Protonated RNA interference vs stupid theories (4)
< 1 MIN READ
0
From optoribogenetics to HelioRiboGenetics (5)
< 1 MIN READ
0
Coherently organized healthy longevity (4)
2 MIN READ
0
pH-dependent viral latency (4)
3 MIN READ
0
The tipping point (revisited): 100K (1)
4 MIN READ
0
Magic traits vs biophysical constraints (1)
3 MIN READ
0
From Wuhan to you (4)
2 MIN READ
0
Richard Axel refutes theistic evolution
2 MIN READ
0
MicroRNA-mediated healthy longevity (3)
3 MIN READ
0
The tipping point (revisited): 95K (5)
< 1 MIN READ
0
The tipping point (revisited): 95K (3)
5 MIN READ
0
Virus-driven sympatric speciation (1)
2 MIN READ
0
Patented Creation vs Evolution of Disease (8)
3 MIN READ
0
Trans-kingdom RNA interactions (3)
3 MIN READ
0
Lewis Thomas (revisited): 90K (7)
3 MIN READ
0
Brokered regulatory leverage: Breaking Bad (2)
7 MIN READ
0
The tipping point (revisited): 90K (1)
4 MIN READ
0
Bastardized health care (7)
3 MIN READ
0
Food energy-as-information, and consciousness
4 MIN READ
0
pH, amino acids, and health: Effects of sunlight and well wishes
2 MIN READ
0
Abiogenesis vs microRNA biogenesis (3)
3 MIN READ
0
Abiogenesis vs microRNA Biogenesis (1)
3 MIN READ
0
The tipping point (revisited): 87K (3)
4 MIN READ
0
The tipping point (revisited): 87K (1)
6 MIN READ
0
The eternal significance of microRNA biogenesis (3)
3 MIN READ
0
Tasting light links energy from creation to adaptation (3)
2 MIN READ
0
Systems biology vs pseudoscientific nonsense
4 MIN READ
0
Preprints obfuscate facts (2)
4 MIN READ
0
RNA processing and disease 2019 (1)
2 MIN READ
0
Ecological adaptation vs neo-Darwinian nonsense (1)
2 MIN READ
0
Blood music orchestrates human life (3)
3 MIN READ
0
Autophagy automagically prevents cancer (2)
2 MIN READ
0
Phytoremediation, Microbiome and CRISPR (1)
3 MIN READ
0
Light-activated continuous environmental tracking (1)
5 MIN READ
0
The tipping point (revisited): 82,000 publications (1)
3 MIN READ
0
The tipping point (revisited): 82,000 publications (4)
4 MIN READ
0
Viral latency vs deadly paleoanthropology (1)
4 MIN READ
0
Light and life at base pair resolution (7)
2 MIN READ
0
Light and life at base pair resolution (4)
4 MIN READ
0
Light and life at base pair resolution (1)
2 MIN READ
0
Hide and seek with science facts (8)
2 MIN READ
0
I can’t fix stupid (3)
3 MIN READ
0
Bottom-up biology
3 MIN READ
0
SfN’s 2018 trap set for Democrats
2 MIN READ
0
10,000 reasons to believe in biophysical constraints (3)
3 MIN READ
0
10,000 reasons to believe in biophysical constraints (2)
6 MIN READ
0
Michael Bloomberg for President (NOT) in 2020
2 MIN READ
0
Creation vs evolution of ribonucleotide removal strategies (2)
2 MIN READ
0
Quantized energy-dependent microRNA-mediated autophagy (2)
< 1 MIN READ
0
Quantized energy-dependent mTORC1 and autophagy
3 MIN READ
0
The concept of a species (4)
2 MIN READ
0
Laws of biology vs no laws of physics
3 MIN READ
0
MicroRNA-mediated alternative splicing (revisited)
4 MIN READ
0
Biologically uninformed science idiot: Self-defense (3)
5 MIN READ
0
Biologically uninformed science idiot: Self-defense (2)
3 MIN READ
0
From quantum physics to quantum souls (4)
8 MIN READ
0
The origin of information (5,4,3,2,1)
3 MIN READ
0
The eternal significance of microRNAs (10)
5 MIN READ
0
Environmental selection is natural selection (2)
2 MIN READ
0
Environmental selection is natural selection
3 MIN READ
0
Laws of Biology / Rules of Life
3 MIN READ
0
Part 3: Light-controlled cell biology (revisited)
3 MIN READ
0
Polymaths and paradigm shifts: From Asimov to Bear (5)
5 MIN READ
0
Polymaths and paradigm shifts: from Asimov to Bear (4)
6 MIN READ
0
Conceptual critique: Innateness vs the death gene (1)
5 MIN READ
0
Diet-driven RNA interference and mental health (4)
8 MIN READ
0
Subatomic: From thermophiles to humans (3)
3 MIN READ
0
A reversible TCA cycle in a thermophile (3)
4 MIN READ
0
A reversible TCA cycle in a thermophile (2)
3 MIN READ
0
Anti-entropic sunlight: Schrödinger’s Creationist Secret? (4)
8 MIN READ
0
The MicroRNAome Strikes Back: A Sokalian hoax (1)
4 MIN READ
0
Autophagy is the antiphage defense strategy (2)
4 MIN READ
0
Enzyme-constrained interethnic diversity (8)
< 1 MIN READ
0
Enzyme-constrained interethnic biodiversity (5)
4 MIN READ
0
The “walking fish” walks straight from quantum physics to quantum souls
6 MIN READ
0
Darwinian adaptation: a clear evolutionary trail?
4 MIN READ
0
Agilent technology and energy-dependent autophagy
8 MIN READ
0
Elsevier fails to support the concept of autophagy
4 MIN READ
0
From Autophagy.pro (transitions)
4 MIN READ
0
The overwhelming ignorance of sex researchers (2)
4 MIN READ
0
Energy-dependent base editing and correction of mutations (2)
9 MIN READ
0
Mouse morphs and primate diversity in 50 years
7 MIN READ
0
Exposing the 2nd Law to more ridicule (1)
6 MIN READ
0
Vulgar Antagonists vs Quantum Effects
3 MIN READ
0
Reporting new scientific truths is not allowed in the USA (2)
6 MIN READ
0
Light-activated error-free DNA repair (4)
3 MIN READ
0
A null mutation and healthy longevity?
4 MIN READ
0
Natural selection for racism and all pathology
6 MIN READ
0
Pheromones biophysically constrain RNA-mediated biodiversity (1)
5 MIN READ
0
The next reformation: 500 years too late? (1)
< 1 MIN READ
0
The next reformation: 500 years too late? (2)
2 MIN READ
0
From base editing to RNA editing (2)
7 MIN READ
0
Until death: Virus-driven failure of multisensory integration (3)
4 MIN READ
0
Energy-dependent structure and function: Until death (5)
4 MIN READ
0
Energy-dependent structure and function: Until death (3)
3 MIN READ
0
Energy-dependent structure and function: Until death (2)
5 MIN READ
0
Energy-dependent structure and function: Until death (1)
4 MIN READ
0
Until death: Virus-driven failure of multisensory integration (1)
4 MIN READ
0
Predicting who wins the 2017 Nobel Prizes
4 MIN READ
0
Evolutionary theories of epigenetic drift (3)
8 MIN READ
0
Evolution outside the context of “the light of evolution”
6 MIN READ
0
Sexual communication signals: New Insights!
10 MIN READ
0
Human Idiocy: The failure to link energy from electrons to ecosystems
19 MIN READ
0
Your indifference is killing you and others
5 MIN READ
0
Your indifference is killing you and others (4)
4 MIN READ
0
Robert Sapolsky’s legacy of atheistic pseudoscientific nonsense
4 MIN READ
0
Automagical protein creation sans energy
9 MIN READ
0
Evolutionary congruence (losers) vs ecological adaptation (winners)
3 MIN READ
0
New Testament Book Cover Refutes Theistic Evolution
7 MIN READ
0
Energy-dependent physical and biophysical constraints (10)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (8)
5 MIN READ
0
Energy-dependent physical and biophysical constraints (7)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (5)
7 MIN READ
0
Energy-dependent physical and biophysical constraints (3)
2 MIN READ
0
The emergence of light as energy from a life-giving star (2)
2 MIN READ
0
Milk-derived miRNAs, circulating microRNAs, DNA repair, and embryonic viability
2 MIN READ
0
MicroRNAs GnRH and the failure of sex research
7 MIN READ
0
God’s shrinking role in salvation (2)
5 MIN READ
0
Food energy-dependent cell type differentiation (2)
10 MIN READ
0
Food energy-dependent epigenetic adaptation (3)
3 MIN READ
0
Food energy-dependent epigenetic adaptation (2)
< 1 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (3)
5 MIN READ
0
Energy as information and constrained endogenous RNA interference (4)
7 MIN READ
0
Draining the academic swamp of parasites
3 MIN READ
0
Virus-driven downsizing of the human brain (4)
2 MIN READ
0
Open Science: Closed to facts about microRNAs
6 MIN READ
0
Functionally interdependent editing and methylation
4 MIN READ
0
Cytosis: Biology Content
7 MIN READ
0
Harvard researchers support young earth creationism
< 1 MIN READ
0
Ab initio cell wall invention, emergence, and evolution (2)
8 MIN READ
0
Energy is information. Objections over ruled. You’re fired!
7 MIN READ
0
Dobzhansky 1973 and precision medicine (5)
3 MIN READ
0
Dobzhansky 1973 and precision medicine
6 MIN READ
0
Mutations: the “driving force” behind human brain complexity?
6 MIN READ
0
Mutations: the "driving force" behind human brain complexity?
6 MIN READ
0
Science journalists or paid propagandists? (2)
3 MIN READ
0
Energy-dependent hydrogen bonds in supercoiled DNA
7 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016
12 MIN READ
0
Bird-brained theorists
< 1 MIN READ
0
Energy-dependent self-organization and self repair
8 MIN READ
0
Explorers who do not know what is known (2)
6 MIN READ
0
Energy-dependent de novo creation and neurogenesis
7 MIN READ
0
Theories vs facts about polycombic adaptation
3 MIN READ
0
Tasting light links energy from creation to adaptation
9 MIN READ
0
Combating evolution: Battlefield medicine vs politicized science
6 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Optogenetics: Let there be virucidal light!
2 MIN READ
0
Energy-dependent maternal-to-zygotic transition
6 MIN READ
1
Epigenetically effected energy-dependent fluorescence
5 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (3)
< 1 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (2)
2 MIN READ
0
From precis to pre-mRNA and proof of concept in F1, F2, F3
6 MIN READ
0
From Precis to Proof in 6000 years (2)
5 MIN READ
0
From Precis to Proof in 6000 years
9 MIN READ
0
Coulombic interactions facilitate polycombic adaptation
5 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (3)
< 1 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (2)
3 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
Demoncrats fight polycombic ecological adaptation
4 MIN READ
0
Biological evolution as a philosophy, not a science
6 MIN READ
0
Hypothesis free pseudoscience vs facts (5)
6 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Anthetical conclusions (2)
5 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
0
Biophysically constrained cell type differentiation
3 MIN READ
0
From angstroms to ecosystems
7 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
Model vs theory: Progress report!
8 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
Cracking the Olfactory Code?
5 MIN READ
0
Modelling life scientifically: RNA-mediated events
12 MIN READ
0
Energy-dependent RNA methylation (6)
9 MIN READ
0
Thermotolerance and longevity (2)
3 MIN READ
0
Energy-dependent biodiversity
5 MIN READ
0
The tipping point? 50, 000 publications (2)
2 MIN READ
0
Countdown to Genetics and Genomics
< 1 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
Half truths support theories without facts
4 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Virus-driven disorder prevention and health promotion
6 MIN READ
0
RNA-mediated DNA modifications
5 MIN READ
0
Bringing RNA back to epigenetics (20 years later)
11 MIN READ
0
Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
0
The Light and Darkness of “Evolution 2.0”
11 MIN READ
0
Will modern human populations adapt to the Zika virus?
5 MIN READ
0
Organic Compounds and the Miracle of Smell and Taste
7 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (5)
10 MIN READ
0
Eugene V. Daev: Chronology
10 MIN READ
0
Juvenile hormone links atoms to ecosystems
3 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
Amino acid substitutions, stress, and human behavior
3 MIN READ
0
Finding peace and π in the light of H bond energy (2)
8 MIN READ
0
Assumptions prove ignorance
5 MIN READ
0
Life history transitions and RNA-mediated survial
2 MIN READ
0
Researchers rename, reshuffle, and reveal their ignorance
3 MIN READ
0
Essential pseudoscientific concepts of atheism
3 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (2)
4 MIN READ
0
Neo-Darwinism vs the neocortex
4 MIN READ
0
Cell type differentiation: atoms to ecosystems
2 MIN READ
0
MicroRNA-encoded behavior
7 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Controled Stem Cell Expansion
3 MIN READ
0
Human pheromone deniers: What’s next?
5 MIN READ
0
700 million years of evolution?
5 MIN READ
0
Mystery machine vs model (3)
2 MIN READ
0
Preventing genomic entropy
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Creating genes and species
3 MIN READ
0
Thermotolerance and Longevity
57 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
Ecology replaces the extended evolutionary synthesis
4 MIN READ
0
The stability of organized genomes (2)
5 MIN READ
0
Hematopoiesis and practopoiesis
4 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Riding the wrong direction
3 MIN READ
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
Unconscious affect (revisited)
2 MIN READ
0
Olfactory perception of genetic information
2 MIN READ
2
RNA-mediated development (2)
< 1 MIN READ
0
Ignoring top-down causation
2 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Viruses and the human-like microbiome
3 MIN READ
0
Appetite for ingesting theories (raw)
< 1 MIN READ
0
One amino acid substitution, genes, and brain activity
3 MIN READ
0
A lighting requirement for life
11 MIN READ
3
Ignoring systems complexity (it’s too complicated)
3 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
How to find a “holy grail” under your nose
3 MIN READ
0
Effect and affect of a single base-pair change
4 MIN READ
0
RNA-mediated silencing of a chromosome
3 MIN READ
0
Re-inventing a completely new thing
4 MIN READ
0
Feedback loops link insects to human brains
2 MIN READ
0
DNA Methylation and organized genomes
7 MIN READ
0
Methylation maintains cell type differences
3 MIN READ
0
Viruses and ecologically adapted animals
2 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Behavior (4): All responses are RNA-mediated in birds
4 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
Walk towards the light
< 1 MIN READ
0
Two types of microRNA are not double agents
2 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
Imagining that data historically supports evolutionary theory
7 MIN READ
0
Military combat training to fight disease (2)
3 MIN READ
0
Epigenetic effects of viruses on cellular homeostasis (2)
2 MIN READ
0
An epigenetic trap (the sequel)
10 MIN READ
0
All of "like kind" in the (bigger) family
6 MIN READ
1
Environment epigenetically shapes the immune system
3 MIN READ
0
Amino acid homeostasis for a Happy New Year!
6 MIN READ
0
From Hydra to humans vs a Lakatosian research program
4 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
Atoms to ecosystems: Evolutionary theory vs the coelacanth
6 MIN READ
0
Jumping back: Science or Pseudoscience? (2)
2 MIN READ
0
Extensive molecular evidence vs ridiculous theories
2 MIN READ
0
Dual genomes: exposing the evolution industry
5 MIN READ
0
One test of bioenergetic health?
2 MIN READ
0
Thermodynamic constraints and ecological adaptations sans evolution
6 MIN READ
0
Eliminating correlations from evolutionary ecology
6 MIN READ
0
The key to science: experimental evidence
5 MIN READ
0
Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
0
More than a bag of chemicals?
2 MIN READ
0
Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
0
Making sense of quotes scattered across disciplines
2 MIN READ
0
De novo DNA methylation?
3 MIN READ
0
We need pattern recognition, not a prologue
6 MIN READ
0
Pharmacogenomics
3 MIN READ
0
Sexual differentiation of cell types in plants
2 MIN READ
0
From deep time into real time: What evolutionary processes?
10 MIN READ
0
No understanding of biodiversity
2 MIN READ
0
Understanding physical forces of ecological variation and adaptation
< 1 MIN READ
0
Eliminating evolutionary theory
3 MIN READ
0
Unassailable evidence vs assumptions
4 MIN READ
0
Forces of "Nature" limit dissemination of information
4 MIN READ
0
Systems biology and memory disorders
3 MIN READ
0
RNA-mediated cell type differentiation and behavior
3 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Physics denied; pseudoscientific nonsense accepted
2 MIN READ
0
Ecological variation and niche construction: 1, 2, 3
6 MIN READ
0
Epigenetically-effected metabolic shifts and ecological adaptations
3 MIN READ
0
Evolving DNA before RNA
4 MIN READ
0
Did our adapted mind evolve? (Revisited)
2 MIN READ
0
Did our adapted mind evolve?
6 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Miracles are not miracles to evolutionary theorists
2 MIN READ
0
Seemingly futile cycles are not thermodynamically futile
3 MIN READ
0
Do bacterial proteins evolve?
3 MIN READ
0
Memory of repression and memory of behavior
2 MIN READ
0
Quantum physics meets Evolutionary Psychology News
2 MIN READ
0
A molecular visualizer of worthwhile molecular biology
2 MIN READ
0
RNA-mediated events found everywhere
2 MIN READ
0
Some neuroscientists think a mutation led to human language development
< 1 MIN READ
0
RNA-mediated ecological adaptation is not evolution
2 MIN READ
0
Exploding genomes and chromosomal rearrangements via RNA-mediated events
2 MIN READ
0
Evolutionary heritage or ecological adaptation? Racism versus reality
4 MIN READ
0
Insect homology and diversity attributed to mutations
2 MIN READ
0
Comparing divergent model organisms
2 MIN READ
1
A microRNA-mediated mechanism that is epigenetically inherited
2 MIN READ
0
Epimutations: Attacking pseudoscientific dogmas
4 MIN READ
0
Order and disorder: Ecological adaptations not mutations
6 MIN READ
0
microRNAs differentiate neuronal cell types
3 MIN READ
0
microRNAs and species relationships
3 MIN READ
0
Drunks and Monkeys: Pseudoscientific nonsense
2 MIN READ
0
The quantum biology of consciousness
3 MIN READ
0
Behavior is receptor-mediated
10 MIN READ
0
Genes and Race: Human History?
2 MIN READ
0
Nutrition, pheromones and cancer (2)
2 MIN READ
0
Ecologically linked adapted ants and brains
2 MIN READ
0
Chromosomal rearrangements and ecological adaptations
4 MIN READ
0
The wrong picture of our evolution
4 MIN READ
0
Jay R. Feierman
3 MIN READ
0
Don't tell the Creationists
2 MIN READ
0
Social experiences epigenetically effect gene networks
2 MIN READ
0
Nutrient-dependent pheromone-controlled stickleback evolution
2 MIN READ
0
Functional coding variants are not mutations
2 MIN READ
0
Understanding the role of mutations and evolution
4 MIN READ
0
Evolution: innovations may have non-adaptive origins (sans mutations)
2 MIN READ
0
Pheromones and cancer
4 MIN READ
0
Are pheromones responsible for human body odour assessment?
2 MIN READ
0
Understanding evolution, adaptation, and phenotype
2 MIN READ
0
Nutrient-dependent / pheromone-controlled social structure
2 MIN READ
0
Hormones effect sensitivity to androsterone
2 MIN READ
0
A “new” view of evolution sans mutations
< 1 MIN READ
0
Epistasis as the primary factor in molecular evolution
4 MIN READ
0
Darwin was wrong
2 MIN READ
0
Epigenetic maintenance of transcription / neuronal migration
2 MIN READ
0
Epigenetics and evolutionary success
< 1 MIN READ
0
Adaptive evolution: Genetic selection against some disorders
3 MIN READ
0
Epigenetic effects underlie sexual preferences IV
< 1 MIN READ
0
Music to our ears and song in birds: a common sense approach
2 MIN READ
0
A mathematical model of phenotypic cause, effects on genes, and affects on behavior
2 MIN READ
0
Non random adaptive evolution
< 1 MIN READ
0
A newly discovered hypothalamic neurogenic niche in the brain
< 1 MIN READ
0
FDA: Just says NO — to ineffective drugs with side effects
< 1 MIN READ
0
Random mutations theory and pervasive mosaic evolution (the brain)
2 MIN READ
0
Random mutations theory and pervasive mosaic evolution (the body)
2 MIN READ
0
Is there a model for that?
3 MIN READ
0
One of the clearest examples of epigenetic effects
< 1 MIN READ
0
The challenges of a Darwinian approach to anything
3 MIN READ
0
MicroRNA binds messenger RNA: Adaptive Evolution
< 1 MIN READ
0
A key mutational event? More story-telling. Olfaction modulates vision.
4 MIN READ
0
A key mutational event? That’s not very likely.
3 MIN READ
0
Desmond Morris Syndrome: No selective advantage
2 MIN READ
0
Fatal attractions: a fear of pheromones
2 MIN READ
0
Consequences and Evolution: The Cause That Works Backwards
4 MIN READ
0
Genetic Influences on Epigenetically Effected Disease
2 MIN READ
0
Forum discussions: the most complained about member (866 words)
3 MIN READ
0
Creation vs Evolution: Expression of a newly found gene
2 MIN READ
0
Sex differences in Alzheimer's and everything else
2 MIN READ
0
Sex differences in Alzheimer’s and everything else
2 MIN READ
0
The Knowing Nose: Chemical Signals Communicate Human Emotions
< 1 MIN READ
0
The logic of gene regulatory networks
3 MIN READ
0
Human Pheromones: Epigenetic Effects of Odors and Their Affects on Behavior
2 MIN READ
0
Creating new genes (and controlling diversity)
2 MIN READ
0
How Species Diversify
2 MIN READ
0
Waiting “forever” for something to happen for the “first” time
2 MIN READ
0
The end of random mutations theory
2 MIN READ
0
Epigenetic effects of viruses on cellular homeostasis
< 1 MIN READ
0
The same neural mechanisms are at work in worms and humans
2 MIN READ
0
The neuroscience of sexual attractions
2 MIN READ
0
A “new” form of natural selection?
2 MIN READ
0
Human pheromones: epigenetic effects
< 1 MIN READ
0
Pheromonemotionally speaking
2 MIN READ
0
Human pheromones: another attempt to change the concept
3 MIN READ
0
Nobel laureate challenges psychologists to clean up their act
2 MIN READ
0
Playing with breasts (e.g, with a new THEORY of why only heterosexual men love them)
3 MIN READ
0
Epigenetic effects on stochastic gene expression and evolutionary psychology
2 MIN READ
0
“Just-So” stories vs scientific explanations
2 MIN READ
0
Adaptive evolution or not: cone receptors in the eye vs odor receptors
2 MIN READ
0
More complicated than 1-2-3
2 MIN READ
0
Bio-CHEMICAL complexity
< 1 MIN READ
0
What to do with research results: Warning!
2 MIN READ
0
Mischaracterizations of adaptive evolution by psychologists and biologists
2 MIN READ
0
Did we descend from lottery winners (Part 2)
2 MIN READ
0
Did we descend from lottery winners or due to adaptive evolution
2 MIN READ
0
Human pheromones and the epigenetic effects of isolation
2 MIN READ
0
Unconscious affects on incalculable genomic interactions
3 MIN READ
0
ENCODE: extant vs extinct species and a clash of world views
4 MIN READ
0
Human pheromones: an epigenetic continuum from microbes to mammals
3 MIN READ
0
Pheromones, Reciprocity, and Prosocial Behavior
3 MIN READ
0
Is the language of God the god problem? (1530 words)
6 MIN READ
0
Envisioning, hindsight bias, plagiarism, or cheating
3 MIN READ
0
The Epigenetics of Drug Development and Cholesterol Levels
< 1 MIN READ
0
Woefully ignorant politicians and popular science
2 MIN READ
0
Pheromones and multicellularity
< 1 MIN READ
0
Epigenetic alterations due to stress
< 1 MIN READ
0
Epigenetic effects on the evolution of behavior
2 MIN READ
0
Human pheromones and autism spectrum disorders
2 MIN READ
0
Human pheromones, the social brain and simple math computations
2 MIN READ
0
Chemical signaling may shed light on how the brain reacts to its environment
2 MIN READ
0
Children’s healthy diets lead to healthier IQ
< 1 MIN READ
0
More bird-brained behavior
2 MIN READ
0
Human pheromones are like sugar (and spice)
< 1 MIN READ
0
Niche construction: ecological, social, neurogenic, and socio-cognitive
2 MIN READ
0
Human pheromones in business strategy
< 1 MIN READ
0
Human pheromones, social deprivation, and brain growth
< 1 MIN READ
0
Human Pheromones and Free Will: a response to Gazzaniga
2 MIN READ
0
Nutrient mixture and memory in patients with early Alzheimer’s
< 1 MIN READ
0
Human pheromones and multi-level selection
< 1 MIN READ
0
Bee research, human sweet perception, human pheromones, and metabolic disorders
< 1 MIN READ
0
Human pheromones and inner conflict about evolution (1102 words)
4 MIN READ
0
Receptor-mediated biological cause and effect
2 MIN READ
0
Human pheromones and the viruses that make us
2 MIN READ
0
A detailed model of physical reality and natural selection (722 words)
3 MIN READ
0
Evolution of the nervous system: conserved GnRH
< 1 MIN READ
0
Human Pheromones and Comparative Epigenomics
2 MIN READ
0
Aging Is Recorded in Our Genes
2 MIN READ
0
Human Pheromone Facts and the Out of Africa Theory
3 MIN READ
0
ecological social neurogenic niche
2 MIN READ
0
Smelling the difference between young and old
< 1 MIN READ
0
Human pheromones and the visual appeal of other people (Part Four)
3 MIN READ
0
A thought experiment
3 MIN READ
0
No New Neurons for Smell?
2 MIN READ
0
Bickering theorists: opinions about selfish genes and group selection
2 MIN READ
1
Human pheromones: Olfaction, odor receptors, learning, memory, mood, brains and behavior
< 1 MIN READ
0
A nutrient chemical and pheromone-dependent neurogenic niche
2 MIN READ
0
Passing On Stress
2 MIN READ
0
Human pheromone- and nutrient-dependent brain development and behavior
2 MIN READ
0
Human pheromones and the visual appeal of other people (Part Three)
2 MIN READ
0
Human pheromones and the visual appeal of other people (Part Two)
2 MIN READ
0
Human pheromones and the visual appeal of other people (Part one)
2 MIN READ
0
Human Pheromones and Consilience
2 MIN READ
0
More than speculation: adaptive evolution in species from microbes to man
2 MIN READ
0
Pattern recognition: How rational is that?
2 MIN READ
0
Human Pheromones and Common Scents: Plants and Perfume
< 1 MIN READ
0
Creation vs Evolution? Pre-existing genetic variation, not random mutation
2 MIN READ
0
Human pheromones and your immune system
< 1 MIN READ
0
People select specific fragrances that suit their individual body odor
< 1 MIN READ
0
Food odors and social odors
2 MIN READ
0
No fooling; visual appeal is not determined by what we see
2 MIN READ
0
A fallacious leap? Ancestral and derived traits
3 MIN READ
0
Modeling odor processing in microbes, mice, and mankind
2 MIN READ
0
Human Pheromones in Socioaffective Neuroscience & Psychology
2 MIN READ
0
Pheromones and the “Bruce effect” in wild or domesticated horses and primates
2 MIN READ
0
They are what they eat, and so are we
2 MIN READ
0
How memory works
2 MIN READ
0
History of intelligence (550 words)
2 MIN READ
0
How could antibiotics alleviate symptoms of schizophrenia?
2 MIN READ
0
A Preoccupation With Modesty…
2 MIN READ
0
Creation of different species without physical barriers (Part Two)
2 MIN READ
0
Pheromones: from microbes to man
< 1 MIN READ
0
The biology of behavior: Seeing more clearly
< 1 MIN READ
0
Explaining a good theory
< 1 MIN READ
0
Researchers Investigate Epigenetic Patterns In Multiple Conditions
< 1 MIN READ
0
Genes not culture drive humans forward (an antithetical approach)
< 1 MIN READ
0
Creation of different species without physical barriers (Part One)
< 1 MIN READ
0
Effects of pheromones on menstrual synchrony and a gay man
2 MIN READ
0
Did viruses make mammals communicate with pheromones?
2 MIN READ
0
Do Pheromones Play a Role in Our Sex Lives: Scientific American
< 1 MIN READ
0
The cause of colony collapse could be a message for all of us
< 1 MIN READ
0
Human Pheromones: 2010 Powerpoint slides and 2011 poster presentation
2 MIN READ
0
Is Love in the Air? Human Pheromones and Axillary Chemistry by George Preti
3 MIN READ
0
Epigentics and the baby connectome
2 MIN READ
0
Cookbook chemistry: food odors and hormones
< 1 MIN READ
0
Epigenetics and the connectome
2 MIN READ
0
Human pheromones and food odors
< 1 MIN READ
0
Pheromones and food odors add more than just color to your world
4 MIN READ
0
Misrepresentations of biologically based cause and effect:
3 MIN READ
0
The Perversion of Science by Evolutionary Psychologists
5 MIN READ
0
Pheromones and the Evolution of Drug Resistance
< 1 MIN READ
0
Human skull study causes evolutionary headache
< 1 MIN READ
0
Docosahexaenoic acid and autism: praying for hope, or preying on hope
< 1 MIN READ
0
Timing is key in the proper wiring of the brain: study
2 MIN READ
0
Behavioral epigenetics
2 MIN READ
0
Cause and effect in biology
< 1 MIN READ
0
Baiting evolutionary psychologists and others who damn religion
3 MIN READ
0
Human pheromones provide clues to personality
< 1 MIN READ
0
Progress in brain research (e.g., starting over)
< 1 MIN READ
0
Baiting the behaviorist(s)
3 MIN READ
0
Theory versus biological facts: Mental modules and models for behavior
2 MIN READ
0
Androstenone odor is less unpleasant for some women
< 1 MIN READ
0
How pheromones work (in 57 words or more)
< 1 MIN READ
0
The Demise of Guys
< 1 MIN READ
0
Pheromones and detectable odors
2 MIN READ
0
Pheromone-enhanced behavior in sexually inexperienced females
2 MIN READ
0
The “yuck” factor: aversion to social odors?
2 MIN READ
0
Avian ‘Axe effect’ attracts attention of females and males
2 MIN READ
0
The Mind’s Eyes: Mindful modeling of brain directed behavior
2 MIN READ
0
Human pheromones: social odors and food odors
< 1 MIN READ
0
Honeybees, food odors, and perfume
< 1 MIN READ
0
Pheromones and a realistic model of sexual differentiation
3 MIN READ
0
Avian recognition of human faces
< 1 MIN READ
0
Human Pheromones Affect Women's Behavior
2 MIN READ
0
A lesser role for olfaction and pheromones in humans?
1 MIN READ
0
Creating a Myth
< 1 MIN READ
0
Study results: Human pheromones influence human behavior
2 MIN READ
0
Pheromones in birds, other mammals, and us
< 1 MIN READ
0
The great pheromone myth revisited (including biological factors in the development of sexuality)
4 MIN READ
0
The great pheromone myth revisited (including biological factors in the development of sexuality)
4 MIN READ
0
Social selection: genetic contribution of viruses to life on earth
< 1 MIN READ
0
Wikipedia comments by James V. Kohl
5 MIN READ
0
Excellent new book about pheromones
< 1 MIN READ
0
Study design| Psychophysics experiment | Perspective on conditioning
< 1 MIN READ
0
Adrenarche and odor preferences
2 MIN READ
0
For ethologists: Observation does not trump molecular biology
2 MIN READ
0
Human Pheromones and The Philosophy of Science
2 MIN READ
0
Natural scent of women linked to increased testosterone and seduction
< 1 MIN READ
0
Genes, Hormones, and Behavior (for other scientists)
4 MIN READ
0
Love at first sight: Selective breeding, pheromones, and Divine intervention
3 MIN READ
0
A fundamental attribution error: Love at first sight
3 MIN READ
0
Human Pheromones
< 1 MIN READ
0
Pheromones and olfaction in the birds and the bees: from yeasts to you
2 MIN READ
0
Pheromones and Physiology: Faculty of 1000: Naturally Selected
2 MIN READ
0
Debunking the myth of pheromones
< 1 MIN READ
0
Tears and fears of pheromones
2 MIN READ
0
Exotic Pheromones and Concentrates
2 MIN READ
0
Marketing vs. the truth about human pheromones
2 MIN READ
0
Human Pheromones, The Scent of Eros, and Cultural Evolution
< 1 MIN READ
0
Molecular biology and social science theory
2 MIN READ
0
Epigenetics, science fiction, and scientific fact
2 MIN READ
0
Results: increased flirtatious behavior and self-reported attraction
2 MIN READ
0
Pheromones and sexual behavior in birds
< 1 MIN READ
0
Is it what he or she sees in you, or is it your pheromones?
2 MIN READ
0
Product comparisons and human pheromone sciences
3 MIN READ
0
Conditioning of the human pair bond by human pheromones
< 1 MIN READ
0
Conditioned sexual arousal to odor
2 MIN READ
0
Scent signals
< 1 MIN READ
0
Men perspire, women glow
< 1 MIN READ
0
Pheromones and signature mixtures
2 MIN READ
0
Comparative biology of pheromonal communication
< 1 MIN READ
1
Food preferences and mate preferences
< 1 MIN READ
0
Presentation on Human Pheromones delivered on August 3, 2010
2 MIN READ
0
Sold on the human VNO?
< 1 MIN READ
0
Effects of pheromones attributed to touch (in mice)
< 1 MIN READ
0
How pheromones work by James V. Kohl
2 MIN READ
0
Pheromones of pregnant women effect prolactin in men
< 1 MIN READ
0
Another book author's comment on "The Great Pheromone Myth"
< 1 MIN READ
0
An attempt to change the concept
< 1 MIN READ
0
Luteinizing hormone, sex, and smell (18 years later)
2 MIN READ
0
